Zeitschrift für Naturforschung C最新文献_第5页

Frontmatter

Zeitschrift für Naturforschung C Pub Date : 2020-01-01 DOI: 10.1515/znc-2020-frontmatter1-2

引用次数: 0

The application of essential oils as a next-generation of pesticides: recent developments and future perspectives 精油作为新一代杀虫剂的应用:最新发展和未来展望

Zeitschrift für Naturforschung C Pub Date : 2019-11-30 DOI: 10.1515/znc-2019-0160

R. Fierăscu, Ioana Catalina Fierascu, C. Dinu-Pîrvu, I. Fierăscu, A. Păunescu

{"title":"The application of essential oils as a next-generation of pesticides: recent developments and future perspectives","authors":"R. Fierăscu, Ioana Catalina Fierascu, C. Dinu-Pîrvu, I. Fierăscu, A. Păunescu","doi":"10.1515/znc-2019-0160","DOIUrl":"https://doi.org/10.1515/znc-2019-0160","url":null,"abstract":"Abstract The overuse of synthetic pesticide, a consequence of the rush to increase crop production, led to tremendous adverse effects, as they constitute a major pollutant for both soils and water, with a high toxicity towards humans and animals and, at the same time, led to development of pest resistance. In the last period, the researches were directed towards finding new solutions with a lower toxicity, less damaging behaviour towards the environment, and a better specificity of action. In this context, the use of essential oils, a complex and unique mixture of compounds, can be considered for the next-generation pesticides. This review aims to present the main applications of the essential oils as insecticides, herbicides, acaricides, and nematicides, as they emerged from the scientific literature published in the last 5 years (2015 to present). From the identified articles within the time period, only those dealing with essential oils obtained by the authors (not commercially available) were selected to be inserted in the review, characterized using established analytical techniques and employed for the envisaged applications. The review is concluded with a chapter containing the main conclusions of the literature study and the future perspectives, regarding the application of essential oils as next-generation pesticides.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"38 1","pages":"183 - 204"},"PeriodicalIF":0.0,"publicationDate":"2019-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89581264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 41

Cytotoxic and anti-inflammatory resorcinol and alkylbenzoquinone derivatives from the leaves of Ardisia sieboldii 三叶草叶间苯二酚和烷基苯醌衍生物的细胞毒性和抗炎作用

Zeitschrift für Naturforschung C Pub Date : 2019-11-26 DOI: 10.1515/znc-2019-0114

M. Shahinozzaman, T. Ishii, M. Halim, M. Hossain, M. Islam, S. Tawata

{"title":"Cytotoxic and anti-inflammatory resorcinol and alkylbenzoquinone derivatives from the leaves of Ardisia sieboldii","authors":"M. Shahinozzaman, T. Ishii, M. Halim, M. Hossain, M. Islam, S. Tawata","doi":"10.1515/znc-2019-0114","DOIUrl":"https://doi.org/10.1515/znc-2019-0114","url":null,"abstract":"Abstract Medicinal plants belonging to the genus Ardisia are traditionally used to cure various human diseases including inflammation and cancer. This study aimed to purify and characterize cytotoxic and anti-inflammatory compounds from Ardisia sieboldii leaves. Bioassay-guided chromatographic analyses yielded three compounds, 2-methyl-5-(8Z-heptadecenyl) resorcinol (1), 5-(8Z-heptadecenyl) resorcinol (2), and ardisiaquinone A (3), whereas liquid chromatography–electrospray ionisation–mass spectrometry chemical profiling revealed the presence of diverse resorcinol and alkylbenzoquinone derivatives in cytotoxic 70% methanol extracts. Chemical structures of 1–3 were confirmed by spectroscopic methods including 1H NMR (nuclear magnetic resonance), 13C NMR, and electrospray ionisation–mass spectrometry. Compounds 1 and 2 were purified from A. sieboldii for the first time, and all three compounds showed cytotoxicity against a panel of cancer cell lines and brine shrimps in a dose-response manner. Among them, compound 2 exhibited the highest cytotoxicity on cancer cells (IC50 values of 8.8–25.7 μM) as well as on brine shrimps (IC50 value of 5.1 μM). Compounds 1–3 exhibited anti-inflammatory effects through inhibiting protein denaturation (IC50 values of 5.8–9.6 μM), cyclooxygenase-2 activity (IC50 values of 34.5–60.1 μM), and nitrite formation in RAW 264.7 cells. Cytotoxic and anti-inflammatory activities of 1–3 demonstrated in this study deserve further investigation for considering their suitability as candidates or leads to develop anticancer and anti-inflammatory drugs.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"121 1","pages":"303 - 311"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75500010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

The Hordeum bulbosum 25S-18S rDNA region: comparison with Hordeum vulgare and other Triticeae 球球Hordeum 25S-18S rDNA区:与普通Hordeum及其他小麦科的比较

Zeitschrift für Naturforschung C Pub Date : 2019-11-26 DOI: 10.1515/znc-2018-0109

O. Georgiev, K. Mishev, M. Krasnikova, M. Kitanova, A. Dimitrova, L. Karagyozov

{"title":"The Hordeum bulbosum 25S-18S rDNA region: comparison with Hordeum vulgare and other Triticeae","authors":"O. Georgiev, K. Mishev, M. Krasnikova, M. Kitanova, A. Dimitrova, L. Karagyozov","doi":"10.1515/znc-2018-0109","DOIUrl":"https://doi.org/10.1515/znc-2018-0109","url":null,"abstract":"Abstract Hordeum vulgare and Hordeum bulbosum are two closely related barley species, which share a common H genome. H. vulgare has two nucleolar organizer regions (NORs), while the NOR of H. bulbosum is only one. We sequenced the 2.5 kb 25S-18S region in the rDNA of H. bulbosum and compared it to the same region in H. vulgare as well as to the other Triticeae. The region includes an intergenic spacer (IGS) with a number of subrepeats, a promoter, and an external transcribed spacer (5′ETS). The IGS of H. bulbosum downstream of 25S rRNA contains two 143-bp repeats and six 128-bp repeats. In contrast, the IGS in H. vulgare contains an array of seven 79-bp repeats and a varying number of 135-bp repeats. The 135-bp repeats in H. vulgare and the 128-bp repeats in H. bulbosum show similarity. Compared to H. vulgare, the 5′ETS of H. bulbosum is shorter. Additionally, the 5′ETS regions in H. bulbosum and H. vulgare diverged faster than in other Triticeae genera. Alignment of the Triticeae promoter sequences suggests that in Hordeum, as in diploid Triticum, transcription starts with guanine and not with adenine as it is in many other plants.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"22 1","pages":"319 - 328"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84961145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Isolation and characterization of antiplasmodial constituents from the marine sponge Coscinoderma sp. 海绵体Coscinoderma sp.抗疟原虫成分的分离与鉴定。

Zeitschrift für Naturforschung C Pub Date : 2019-11-26 DOI: 10.1515/znc-2019-0039

Huijeong Jeong, A. Latif, C. Kong, Y. Seo, Yeon-Ju Lee, S. Dalal, M. Cassera, D. Kingston

引用次数: 3

Fisetin effects on cell proliferation and apoptosis in glioma cells 非瑟酮对胶质瘤细胞增殖和凋亡的影响

Zeitschrift für Naturforschung C Pub Date : 2019-11-26 DOI: 10.1515/znc-2019-0098

F. Pak, Pinar Oztopcu-Vatan

{"title":"Fisetin effects on cell proliferation and apoptosis in glioma cells","authors":"F. Pak, Pinar Oztopcu-Vatan","doi":"10.1515/znc-2019-0098","DOIUrl":"https://doi.org/10.1515/znc-2019-0098","url":null,"abstract":"Abstract This research investigated the antiproliferative effects of 1–500 μM fisetin in T98G and BEAS-2B cells by MTT assay. The IC50 of fisetin in T98G cells for 24 and 48 h were 93 and 75 μM, respectively. Apoptotic alterations of fisetin-treated T98G cells were observed by transmission electron microscopy. BEAS-2B was then used in comparison to T98G cells to determine the cytotoxic effects of fisetin. The IC50 of fisetin for 24 and 48 h were recorded as 270 and 90 μM in BEAS-2B cells, respectively. Different concentrations of fisetin were selected to determine the apoptotic and necrotic effects. Consequently, fisetin was determined to have more apoptotic effects in T98G than BEAS-2B cells, dose- and time-dependently. Moreover, fisetin was found to have cytotoxicity at lower doses in T98G cells compared to carmustine, as positive control. CASPASE 3, CASPASE 9, CASPASE 8, and BAX expressions were increased by the selected fisetin doses of 25 and 50 μM, while that of BCL-2 and survivin was reduced in T98G cells. These results will serve as an essential basis of future in vitro and in vivo studies, in the continuous search for alternative treatment agents for gliomas.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"143 1","pages":"295 - 302"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81788161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A new ursane-type triterpene oxoglucopyranoside from Crossopteryx febrifuga 一种新的熊型三萜氧葡萄糖吡喃苷

Zeitschrift für Naturforschung C Pub Date : 2019-11-26 DOI: 10.1515/znc-2019-0113

Modjinan Kayangar, Raymond Ngansop Nono, J. Kühlborn, R. Tchuenguem, B. Ponou, K. Jenett‐Siems, R. Teponno, J. Dzoyem, T. Opatz, M. Melzig, L. Tapondjou

{"title":"A new ursane-type triterpene oxoglucopyranoside from Crossopteryx febrifuga","authors":"Modjinan Kayangar, Raymond Ngansop Nono, J. Kühlborn, R. Tchuenguem, B. Ponou, K. Jenett‐Siems, R. Teponno, J. Dzoyem, T. Opatz, M. Melzig, L. Tapondjou","doi":"10.1515/znc-2019-0113","DOIUrl":"https://doi.org/10.1515/znc-2019-0113","url":null,"abstract":"Abstract A new saponin, 3-O-β-d-3-oxo-glucopyranosyl-ursa-12,20(30)-diene-27,28-dioic acid (1), was isolated from the methanol extract of stem bark of Crossopteryx febrifuga together with the known 3β-d-glucopyranosyl-ursa-12,20(30)-diene-27,28-dioic acid (2), shanzhiside methyl ester (3), shanzhiside (4), β-sitosterol (5), β-sitosterol-3-O-β-d-glucopyranoside (6), ursa-12,20(30)-diene-27,28-dioic acid (7), hederagenin (8), and oleanolic acid (9). The structures were established by comprehensive interpretation of their spectral data 1D- (1H and 13C), 2D-NMR (1H-1H COSY, HMQC, HMBC), spectroscopic, and electrospray ionisation time-of-flight mass spectrometry analysis. The isolated compounds and extracts were screened for their antibacterial properties. Although the EtOAc and n-BuOH extracts exhibited considerable antibacterial activity against Pseudomonas aeruginosa with minimum inhibitory concentration (MIC) value of 32 μg/mL, compounds 2 and 8 showed moderate activity against Enterococcus faecalis with MIC values of 256 and 128 μg/mL, respectively. The new compound (1) exhibited a moderate antibacterial activity against Staphylococcus aureus with an MIC value of 512 μg/mL.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"12 1","pages":"289 - 293"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89337362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Frontmatter

Zeitschrift für Naturforschung C Pub Date : 2019-11-01 DOI: 10.1515/znc-2019-frontmatter11-12

引用次数: 0

Isolation and identification of tuliposides D and F from tulip cultivars 郁金香脂苷D和F的分离鉴定

Zeitschrift für Naturforschung C Pub Date : 2019-10-22 DOI: 10.1515/znc-2019-0123

Taiji Nomura, S. Ogita, Y. Kato

引用次数: 3

Identification and characterization of novel short-type BmPGRP-S4 from the silkworm, Bombyx mori, involved in innate immunity 家蚕先天免疫相关基因新型短型BmPGRP-S4的鉴定与表征

Zeitschrift für Naturforschung C Pub Date : 2019-10-11 DOI: 10.1515/znc-2019-0093

Qiang Wang, Meijia Ren, Xiaoyong Liu, H. Xia, Keping Chen

{"title":"Identification and characterization of novel short-type BmPGRP-S4 from the silkworm, Bombyx mori, involved in innate immunity","authors":"Qiang Wang, Meijia Ren, Xiaoyong Liu, H. Xia, Keping Chen","doi":"10.1515/znc-2019-0093","DOIUrl":"https://doi.org/10.1515/znc-2019-0093","url":null,"abstract":"Abstract Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that can recognize bacterial peptidoglycans and trigger the innate immune response of insects. Here, we identified and characterized a novel short-type Bombyx mori peptidoglycan recognition proteins short-4 (BmPGRP-S4) in a lepidopteran insect, Bombyx mori. BmPGRP-S4 exhibited a cDNA sequence length of 600 bp, encoding 199 aa with a protein molecular weight of 22 kDa. Multiple sequence alignment revealed that BmPGRP-S4 contains a conserved PGRP domain. Quantitative real-time polymerase chain reaction analysis showed that BmPGRP-S4 is highly expressed in the early developmental stages of silkworm larvae and presents tissue-specific expression in hemocytes. Interestingly, BmPGRP-S4 expression is significantly induced by bacterial infection in the midgut, fat body, and hemocytes. Furthermore, a dual luciferase reporter gene assay revealed that BmPGRP-S4 can activate the expression of the antimicrobial peptide genes lebocin, moricin, cecropin D, cecropin B, and attacin. Taken together, these results suggest that BmPGRP-S4 plays an important role in the innate immune response of silkworms.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"41 1","pages":"13 - 21"},"PeriodicalIF":0.0,"publicationDate":"2019-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88070198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6