Zeitschrift für Naturforschung C最新文献_第10页

Characterization of the cardiac glycoside and lipid profiles of Strophanthus kombé Oliv. seeds 茯苓心糖苷和脂质谱的研究。种子

Zeitschrift für Naturforschung C Pub Date : 2016-03-01 DOI: 10.1515/znc-2015-0186

D. Knittel, P. Lorenz, U. Huber, F. Stintzing, Dietmar Kammerer

{"title":"Characterization of the cardiac glycoside and lipid profiles of Strophanthus kombé Oliv. seeds","authors":"D. Knittel, P. Lorenz, U. Huber, F. Stintzing, Dietmar Kammerer","doi":"10.1515/znc-2015-0186","DOIUrl":"https://doi.org/10.1515/znc-2015-0186","url":null,"abstract":"Abstract The seeds of Strophanthus kombé Oliv. are known to contain high levels of cardioactive compounds. However, the therapeutic use of Strophanthus in the treatment of cardiopathy requires more detailed knowledge of the compound profile to profit from the full potential of Strophanthus preparations. Therefore, the objective was to characterize the cardenolide profile and lipophilic constituents in S. kombé seeds using methods applicable in routine quality control. Freshly prepared S. kombé seed extracts were analyzed without previous sample clean-up using a novel HPLC-DAD-MSn method. In addition, seed oils were analyzed by GC-MS following derivatization of the lipids. More than 20 cardenolides were tentatively assigned in the seed extracts including strophanthidin, strophanthidol, periplogenin and strophanthidinic acid aglycones, carrying various saccharide moieties. The findings revealed the presence of eight novel cardenolides, which have not been described for S. kombé so far. The occurrence of strophanthidinic acid derivatives was verified by comparison with synthesized strophanthidinic acid-cymaropyranoside. GC-MS characterization of the oils mainly revealed the presence of fatty acids, especially oleic acid and linoleic acid, as well as phytosterols, the latter representing intermediates of cardenolide biosynthesis. In summary, these findings broaden our knowledge on the secondary metabolism of Strophanthus.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"32 1","pages":"55 - 64"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84572752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Thonningiiflavanonol A and thonningiiflavanonol B, two novel flavonoids, and other constituents of Ficus thonningii Blume (Moraceae) 桑科桑榕中两种新型黄酮A、B及其他成分

Zeitschrift für Naturforschung C Pub Date : 2016-03-01 DOI: 10.1515/znc-2015-0147

P. Ango, D. G. Kapche, G. Fotso, Christian D Fozing, Elizabeth M. O. Yeboah, Renameditswe Mapitse, I. Demirtaş, B. Ngadjui, S. Yeboah

引用次数: 12

Some rape/canola seed oils: fatty acid composition and tocopherols 一些油菜/菜籽油:脂肪酸组成和生育酚

Zeitschrift für Naturforschung C Pub Date : 2016-03-01 DOI: 10.1515/znc-2016-0003

B. Matthaus, M. Özcan, F. Al Juhaimi

引用次数: 43

Chemical constituents and antiproliferative effects of cultured Mougeotia nummuloides and Spirulina major against cancerous cell lines 大螺旋藻和黑木的化学成分及其对癌细胞的抗增殖作用

Zeitschrift für Naturforschung C Pub Date : 2016-03-01 DOI: 10.1515/znc-2016-0010

R. Erenler, Köksal Pabuçcu, A. S. Yaglıoglu, I. Demirtaş, Fatih Gul

{"title":"Chemical constituents and antiproliferative effects of cultured Mougeotia nummuloides and Spirulina major against cancerous cell lines","authors":"R. Erenler, Köksal Pabuçcu, A. S. Yaglıoglu, I. Demirtaş, Fatih Gul","doi":"10.1515/znc-2016-0010","DOIUrl":"https://doi.org/10.1515/znc-2016-0010","url":null,"abstract":"Abstract In this study, the effect of Mougeotia nummuloides and Spirulina major on Vero cells (African green monkey kidney), C6 cells (rat brain tumor cells) and HeLa cells (human uterus carcinoma) was investigated in vitro. The antiproliferative effect of the methanol extract of M. nummuloides and S. major compared with 5-fluorourasil (5-FU) and cisplatin was tested at various concentrations using the BrdU Cell Proliferation ELISA. Both M. nummuloides and S. major extracts significantly inhibited the proliferation of Vero, HeLa and C6 cancer cell lines with IC50 and IC75 values. The M. nummuloides extract exhibited higher activity than 5-FU and cisplatin on Vero and C6 cells at high concentrations. The S. major extract revealed better antifproliferative activity than standards against Vero cells at 500 μg/mL. The compounds of methanol extracts were determined by GC-MS after the silylation process. Trehalose, monostearin and 1-monopalmitin were detected as major products in the M. nummuloides extract where as in the S. major extract; monostearin, 1-monopalmitin and hexyl alcohol were the main constituents.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"27 1","pages":"87 - 92"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89467384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

The physico-chemical properties of some citrus seeds and seed oils 柑桔类种子及其油的理化性质

Zeitschrift für Naturforschung C Pub Date : 2016-03-01 DOI: 10.1515/znc-2016-0004

F. Juhaimi, B. Matthäus, M. Özcan, K. Ghafoor

引用次数: 18

Acute toxicity, antiedematogenic activity, and chemical constituents of Palicourea rigida Kunth 硬毛孢的急性毒性、抗水肿活性及化学成分研究

Zeitschrift für Naturforschung C Pub Date : 2016-03-01 DOI: 10.1515/znc-2015-0036

V. G. Alves, Elisa A. da Rosa, L. L. D. de Arruda, B. Rocha, C. B. Bersani Amado, S. Santin, A. Pomini, C. C. da Silva

引用次数: 5

Fatty acid composition of achenes of Cirsium taxa (Asteraceae, Carduoideae) from Turkey 土耳其卷叶卷叶卷叶类群瘦果的脂肪酸组成

Zeitschrift für Naturforschung C Pub Date : 2016-03-01 DOI: 10.1515/znc-2015-0128

M. Ozcan, F. Ayaz, Y. Ozogul, R. Glew, F. Ozogul

{"title":"Fatty acid composition of achenes of Cirsium taxa (Asteraceae, Carduoideae) from Turkey","authors":"M. Ozcan, F. Ayaz, Y. Ozogul, R. Glew, F. Ozogul","doi":"10.1515/znc-2015-0128","DOIUrl":"https://doi.org/10.1515/znc-2015-0128","url":null,"abstract":"Abstract The fatty acid compositions and total oil contents in achenes of 22 Cirsium taxa collected from different natural habitats in Turkey were investigated. The range of total fat in the taxa varied from 1.7% to 13.3%. The taxa contained palmitic (C16:0), stearic (C18:0), oleic (C18:1n-9), linoleic (C18:2n-6), and α-linolenic (C18:3n-3) acid. Polyunsaturated fatty acids had the highest level, ranging from 52.1% to 75.2% (C18:2n-6) and 0.5%–17.3% (C18:3n-3). Total saturated (6.9%–17.4%), monounsaturated (11.7%–28.9%), and polyunsaturated (57.4%–79.9%) fatty acids varied substantially, whereas total unsaturated fatty acids ranged from 70.6% to 91.3%. Considerable variation was observed (P<0.05) within each taxon for these fatty acids, especially α-linolenic acid (C18:3n-3). Fatty acid compositions of the 22 taxa were compared by cluster analysis (UPGMA) and principle component analysis (PCA) based on six major fatty acids. This is the first report on the lipid content and fatty acid composition of achenes of Cirsium taxa growing in different areas of Turkey. Fatty acid profiles, relative proportions and levels of fatty acids can be used as additional biochemical markers in the taxonomy of Cirsium.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"2010 1","pages":"45 - 54"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86279892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Alkaloid profiles and acetylcholinesterase inhibitory activities of Fumaria species from Bulgaria 保加利亚富马菌生物碱谱及乙酰胆碱酯酶抑制活性

Zeitschrift für Naturforschung C Pub Date : 2016-01-01 DOI: 10.1515/znc-2014-4179

R. Vrancheva, Ivan Georgiev Ivanov, I. Aneva, I. Dincheva, I. Badjakov, A. Pavlov

引用次数: 12

Unguisin F, a new cyclic peptide from the endophytic fungus Mucor irregularis 从内生真菌不规则毛霉中提取的一种新的环状肽

Zeitschrift für Naturforschung C Pub Date : 2016-01-01 DOI: 10.1515/znc-2015-0137

S. H. Akoné, G. Daletos, Wenhan Lin, P. Proksch

引用次数: 13

Structural and evolutionary relationships among RuBisCOs inferred from their large and small subunits RuBisCOs之间的结构和进化关系从它们的大小亚基推断出来

Zeitschrift für Naturforschung C Pub Date : 2016-01-01 DOI: 10.1515/znc-2016-0014

F. Xiang, Yuanping Fang, Jun Xiang

{"title":"Structural and evolutionary relationships among RuBisCOs inferred from their large and small subunits","authors":"F. Xiang, Yuanping Fang, Jun Xiang","doi":"10.1515/znc-2016-0014","DOIUrl":"https://doi.org/10.1515/znc-2016-0014","url":null,"abstract":"Abstract Ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the key enzyme to assimilate CO2 into the biosphere. The nonredundant structural data sets for three RuBisCO domain superfamilies, i.e. large subunit C-terminal domain (LSC), large subunit N-terminal domain (LSN) and small subunit domain (SS), were selected using QR factorization based on the structural alignment with QH as the similarity measure. The structural phylogenies were then constructed to investigate a possible functional significance of the evolutionary diversification. The LSC could have occurred in both bacteria and archaea, and has evolved towards increased complexity in both bacteria and eukaryotes with a 4-helix–2-helix–2-helix bundle being extended into a 5-helix–3-helix–3-helix one at the LSC carboxyl-terminus. The structural variations of LSN could have originated not only in bacteria with a short coil, but also in eukaryotes with a long one. Meanwhile, the SS dendrogram can be contributed to the structural variations at the βA–βB-loop region. All the structural variations observed in the coil regions have influence on catalytic performance or CO2/O2 selectivities of RuBisCOs from different species. Such findings provide insights on RuBisCO improvements.","PeriodicalId":23894,"journal":{"name":"Zeitschrift für Naturforschung C","volume":"28 1","pages":"181 - 189"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79030965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0