Wiener Klinische Wochenschrift最新文献

{"title":"Women's satisfaction with breast reconstruction after mastectomy and a survey on the decision process for type of reconstructive surgery.","authors":"Ingrid Jelinek, Rupert Koller, Michael Kundi","doi":"10.1007/s00508-025-02526-6","DOIUrl":"https://doi.org/10.1007/s00508-025-02526-6","url":null,"abstract":"<p><strong>Background: </strong>Breast reconstruction is an option for women after breast cancer surgery to improve the quality of life. While data about satisfaction after reconstruction are available, little is known about the decision process and about factors shaping this process.</p><p><strong>Methods: </strong>From 100 selected women, 72 women between 30 and 65 years of age (median 50.3 years, interquartile range 44-57 years) with breast reconstruction conducted in a single center in Vienna (Austria) consented to take part in this study. The role of family, social environment and healthcare providers during decision making, body image, thoughts about hospital stay and potential complications were assessed by a questionnaire. The decision for autologous tissue versus silicone implants was analyzed by structural equation modelling.</p><p><strong>Results: </strong>Overall, 69% of the women chose autologous tissue either alone or in combination with a silicone prosthesis. Visual appearance was the most important reason (86%) for choosing reconstruction. Thoughts about the stay in hospital and possible complications were important for the mediating role of healthcare providers in deciding on the type of reconstruction. If women had no concerns about complications they made the choice on their own and favoring autologous tissue reconstruction. In contrast, if such concerns existed women tended to seek help from healthcare providers and tended to choose silicone implants.</p><p><strong>Conclusion: </strong>Counselling of women after breast cancer surgery and during decision making for breast reconstruction should include an esthetic outcome but also possible complications and related length of hospital stay.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective cross-sectional study on district-based socioeconomic status and prostate cancer diagnosis.","authors":"Ozan Yurdakul, Altug Tuncel, Melanie R Hassler, Katharina Oberneder, David V Gamez, Mesut Remzi","doi":"10.1007/s00508-024-02449-8","DOIUrl":"10.1007/s00508-024-02449-8","url":null,"abstract":"<p><strong>Introduction: </strong>Socioeconomic disparities have been linked to delayed prostate cancer diagnosis and poorer outcomes in various countries. This study aims to evaluate the socioeconomic disparities in prostate cancer diagnostics in Vienna, Austria, by examining initial prostate-specific antigen values and age at diagnosis across different districts and nationalities.</p><p><strong>Methods: </strong>This retrospective study included 1356 prostate cancer patients treated at the Medical University of Vienna between 2012 and 2022. Influence of residential districts and nationalities of the patients on the initial prostate-specific antigen (iPSA) value and on the age at diagnosis were analyzed. Patient data, including iPSA values, residential districts, and nationalities, were retrieved from the hospital's internal documentation system. The information on average income of residential districts was obtained from the City of Vienna's municipality data. Nationalities were grouped into EU and non-EU categories. Statistical analyses, including linear regression and t‑tests, were performed to examine the relationship between iPSA values, age at diagnosis, and socioeconomic variables. Linear regression was used to analyze the relationship between district income and both iPSA values and age at diagnosis.</p><p><strong>Results: </strong>The study found no significant differences in iPSA values and age at diagnosis between patients from higher income and lower income districts. Additionally, there were no significant differences among individual districts or between EU and non-EU nationals.</p><p><strong>Conclusion: </strong>The findings suggest that the Austrian healthcare system provides equitable access to prostate cancer diagnostics across different socioeconomic groups.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"225-230"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myeloid sarcoma of the heart-A clinicopathological correlation.","authors":"Kristijan Skok, Martin Zacharias, Nicolas Verheyen, Stefan Hatzl, Laura Scholz, Cord Langner, Gerald Hoefler, Fotini Rosi Vagena","doi":"10.1007/s00508-024-02478-3","DOIUrl":"10.1007/s00508-024-02478-3","url":null,"abstract":"<p><p>A 63-year-old woman with a history of acute myeloid leukemia followed by stem cell transplantation presented with acute heart failure. Transthoracic echocardiography revealed a preserved left ventricular ejection fraction with severe ventricular hypertrophy and signs of elevated filling pressures indicating infiltrative cardiomyopathy. She died from cardiac arrest due to cardiogenic shock. The autopsy revealed an enlarged heart with a fish-flesh appearance. Here, we describe a rare case of a myeloid sarcoma of the heart.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"251-254"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does surgeon or hospital volume influence outcome in dedicated colorectal units?-A Viennese perspective.","authors":"Gabor J Schuld, Lukas Schlager, Matthias Monschein, Stefan Riss, Michael Bergmann, Peter Razek, Anton Stift, Lukas W Unger","doi":"10.1007/s00508-024-02405-6","DOIUrl":"10.1007/s00508-024-02405-6","url":null,"abstract":"<p><strong>Objective: </strong>A clear relationship between higher surgeon volume and improved outcomes has not been convincingly established in rectal cancer surgery. The aim of this study was to evaluate the impact of individual surgeon's caseload and hospital volume on perioperative outcome.</p><p><strong>Methods: </strong>We retrospectively analyzed 336 consecutive patients undergoing oncological resection for rectal cancer at two Viennese hospitals between 1 January 2015 and 31 December 2020. The effect of baseline characteristics as well as surgeons' caseloads (low volume: 0-5 cases per year, high volume > 5 cases per year) on postoperative complication rates (Clavien-Dindo Classification groups of < 3 and ≥ 3) were evaluated.</p><p><strong>Results: </strong>No differences in baseline characteristics were found between centers in terms of sex, smoking status, or comorbidities of patients. Interestingly, only 14.7% of surgeons met the criteria to be classified as high-volume surgeons, while accounting for 66.3% of all operations. There was a significant difference in outcomes depending on the treating center in univariate and multivariate binary logistic regression analysis (odds ratio (OR) = 2.403, p = 0.008). Open surgery was associated with lower complication rates than minimally invasive approaches in univariate analysis (OR = 0.417, p = 0.003, 95%CI = 0.232-0.739) but not multivariate analysis. This indicated that the center's policy rather than surgeon volume or mode of surgery impact on postoperative outcomes.</p><p><strong>Conclusion: </strong>Treating center standards impacted on outcome, while individual caseload of surgeons or mode of surgery did not independently affect complication rates in this analysis. The majority of rectal cancer resections are performed by a small number of surgeons in Viennese hospitals.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"231-236"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical and oncological outcome after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma : A retrospective single center experience.","authors":"Muhammad Safwan, Ishwa Shakir, Saman Naz","doi":"10.1007/s00508-024-02493-4","DOIUrl":"10.1007/s00508-024-02493-4","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"244-245"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of family history with patient characteristics and prognosis in a large European gastroesophageal cancer cohort.","authors":"Hannah C Puhr, Luzia Berchtold, Linda Zingerle, Melanie Felfernig, Lisa Weissenbacher, Gerd Jomrich, Reza Asari, Sebastian F Schoppmann, Gerald W Prager, Elisabeth S Bergen, Anna S Berghoff, Matthias Preusser, Aysegül Ilhan-Mutlu","doi":"10.1007/s00508-024-02432-3","DOIUrl":"10.1007/s00508-024-02432-3","url":null,"abstract":"<p><strong>Introduction: </strong>The role of the family history in the development and prognosis of gastroesophageal cancer is a controversially discussed topic as appropriate data from western cohorts are lacking. This study aims to explore its associations with disease and outcome parameters in a large European cohort.</p><p><strong>Methods: </strong>We retrospectively analyzed self-reported family history in patients with gastroesophageal cancer treated between 1 January 1990 and 31 December 2021 at the Medical University of Vienna. Association analyses with patient characteristics, tumor characteristics, symptoms and overall survival (OS) were performed.</p><p><strong>Results: </strong>In our cohort of 1762 gastroesophageal cancer patients, 592 (34%) reported a positive family history of cancer (159, 9%, gastroesophageal cancer). No associations were found with histopathological parameters or initial symptoms; however, a positive family history correlated with female gender (cancer in general: p = 0.011; gastroesophageal cancer: p = 0.015). Family history of cancer in general was associated with earlier cancer stages (p = 0.04), higher BMI (p = 0.005), and alcohol consumption (p = 0.010), while a positive history for gastroesophageal cancer was associated with higher age at diagnosis (p = 0.002) and stomach cancer (p = 0.002). There was no statistically significant association of positive family history with OS (p = 0.1, p = 0.45), also not in subgroups for histology (adeno and squamous cell), number of family members and degree of relative.</p><p><strong>Conclusion: </strong>Our results emphasize that a positive family history is neither statistically significantly associated with prognosis nor with specific histopathological features in patients with gastroesophageal cancer. Yet, associations with distinct patient characteristics and positive family history indicate that specific subgroups might profit from endoscopic surveillance. Prospective studies are warranted to investigate these findings further.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"214-223"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Association of family history with patient characteristics and prognosis in a large European gastroesophageal cancer cohort.","authors":"Hannah C Puhr, Luzia Berchtold, Linda Zingerle, Melanie Felfernig, Lisa Weissenbacher, Gerd Jomrich, Reza Asari, Sebastian F Schoppmann, Gerald W Prager, Elisabeth S Bergen, Anna S Berghoff, Matthias Preusser, Aysegül Ilhan-Mutlu","doi":"10.1007/s00508-024-02456-9","DOIUrl":"10.1007/s00508-024-02456-9","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"224"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of breast cancer incidence and cancer stages before and after the introduction of the Austrian national breast cancer screening program in the federal state of Salzburg : Real-world data from the Tumor Registry Salzburg.","authors":"Simon Peter Gampenrieder, Marc Vaisband, Gabriel Rinnerthaler, Lukas Weiss, Bernhard Jaud, Martin Sprenger, Richard Greil","doi":"10.1007/s00508-025-02508-8","DOIUrl":"10.1007/s00508-025-02508-8","url":null,"abstract":"<p><strong>Background: </strong>In January 2014 a national, quality-assured breast cancer screening program was introduced in Austria. To investigate if the program reduced the incidence of advanced breast cancer stages, we evaluated data from the Tumor Registry Salzburg, which records all cancer cases diagnosed in the federal state of Salzburg, Austria. Secondary objectives were changes in nodal status and the influence of age and urban or rural residence on stage distribution.</p><p><strong>Methods: </strong>Female patients resident in the federal state of Salzburg with a first diagnosis of breast cancer in 2010-2022 were included. For the main objectives, patients aged 45-69 years with known tumor stages were evaluated. Age-standardized incidence rates were compared between 2010-2013 and 2016-2019 by normal approximation of Poisson rates and stage distributions by ordinal logistic regression.</p><p><strong>Results: </strong>The distribution of stages 0-IV did not differ significantly between 2010-2013 and 2016-2019 (P = 0.380). The percentage of stage IV breast cancer decreased numerically from 9.4-4.5% (P = 0.141). No statistically significant differences between early stages (0-I), advanced stages (II-IV, P = 0. 524) and between lymph node negative and positive cases (P = 0.538) were detected. Neither age nor urban/rural residence had a substantial influence on tumor stage. Interestingly, the breast cancer incidence rates in Salzburg decreased nonsignificantly after the introduction of screening: annual 245.7 vs. 229.8 cases per 100,000 standard population (P = 0.483).</p><p><strong>Conclusion: </strong>Our findings do not support the assumption that the introduction of the Austrian breast cancer screening program significantly reduced advanced stage breast cancer in the federal state of Salzburg compared to the opportunistic screening established before.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"205-213"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical and oncological outcome after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma : A retrospective single center experience.","authors":"Catharina Müller, Michael Bergmann, Anton Stift, Thomas Bachleitner-Hofmann, Stefan Riss","doi":"10.1007/s00508-024-02460-z","DOIUrl":"10.1007/s00508-024-02460-z","url":null,"abstract":"<p><strong>Background: </strong>Peritoneal mesothelioma (PM) is a rare disease with various histopathological subtypes. For malignant peritoneal mesothelioma and borderline subgroups locoregional therapy with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been implemented. The aim of our study was to retrospectively present the outcome after CRS and HIPEC for patients with different subtypes of peritoneal mesothelioma.</p><p><strong>Methods: </strong>In total 15 patients received CRS and HIPEC due to peritoneal mesothelioma at our tertiary referral hospital between 2013 and 2022. Surgical and oncologic outcomes of 14 of those patients were retrospectively evaluated as one patient was lost to follow-up.</p><p><strong>Results: </strong>The cohort consisted of 9 patients with diffuse malignant peritoneal mesothelioma (64.3%), 3 patients with multicystic peritoneal mesothelioma (21.4%) and 2 patients with well-differentiated peritoneal mesothelioma (14.3%). Complete cytoreduction was possible in 85.7% (n = 12). The major complication rate was 28.6% (n = 4) and the reoperation rate was 14.3% (n = 2). Median follow-up was 55 months (standard error, SE 15.0%, 95% confidence interval, CI 25.6-84.4 months). Over this time period 64.3% (n = 9) had no evidence of disease, 21.4% (n = 3) were alive with disease and 14.3% (n = 2) died of peritoneal mesothelioma. The median recurrence-free survival of patients was 13 months (SE 13.0%, 95% CI 0.0-32.2 months). None of the patients with multicystic peritoneal mesothelioma had evidence of disease at the time of last follow-up.</p><p><strong>Conclusion: </strong>Patients with peritoneal mesothelioma should receive locoregional treatment as good oncological results can be achieved with reasonable postoperative morbidity. Thus, awareness is necessary for this rare but potentially aggressive disease to offer the best medical care.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"237-243"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MUW researcher of the month.","authors":"","doi":"10.1007/s00508-025-02535-5","DOIUrl":"https://doi.org/10.1007/s00508-025-02535-5","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 7-8","pages":"255-256"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}