Wiener Klinische Wochenschrift最新文献

{"title":"[Management of convulsive status epilepticus in childhood].","authors":"Sarah Glatter, Francesco Cardona, Eugen Trinka, Markus Leitinger, Martha Feucht","doi":"10.1007/s00508-025-02570-2","DOIUrl":"10.1007/s00508-025-02570-2","url":null,"abstract":"<p><p>Convulsive status epilepticus (CSE) is one of the most common pediatric emergencies. The duration of CSE is critical, whereby with increasing duration the cessation of CSE becomes more difficult or less probable and mortality as well as short and long-term complications increase exponentially. Prompt diagnostics and treatment of pediatric CSE (PCSE) are therefore essential. In contrast to adulthood, updated generally accepted guidelines for a structured approach do not yet exist. Based on current evidence the Austrian EpiCARE centers of the Department of Pediatrics at the Medical University Vienna in close cooperation with the Department of Neurology at the Christian Doppler University Hospital in Salzburg developed a continuous documentation process beginning with the time when the young patient was last seen free of symptoms, through prehospital interventions up to admission in the emergency outpatient department and further up to the admission in the pediatric intermediate care (IMC) or intensive care units (PIC). In addition, a pocket card with detailed information on structured specific diagnostics and treatment was developed, which is aimed at guaranteeing rapid adequate measures independent of the staffing by medical personnel (e.g., during night shifts or at weekends). The concept presented here is aimed at sensitizing prehospital and emergency physicians as well as pediatricians at local initial admission centers to further harmonize in-/inter-house treatment standards with the intention of preventing refractory or superrefractory PCSE and possible resulting complications.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 Suppl 7","pages":"233-241"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12441103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mid-term results of intra-articular calcaneal fractures treated with minimally invasive two-point distractor : Single center study with 6-year follow-up.","authors":"Matthias Stark, Domenik Popp, Lukas Schmoelz, Kevin Doering, Kerstin Stark, Arastoo Nia","doi":"10.1007/s00508-024-02476-5","DOIUrl":"10.1007/s00508-024-02476-5","url":null,"abstract":"<p><strong>Background: </strong>Displaced intra-articular calcaneal fractures are a complication-ridden injury to treat and there are various treatment techniques to address this injury. The aim of this study was to evaluate the mid-term outcome of a percutaneous two-point distractor technique in patients with displaced intra-articular calcaneal fractures.</p><p><strong>Methods: </strong>A retrospective data analysis of patients with intra-articular calcaneal fractures treated in a level 1 trauma center was conducted. The patients were subsequently invited for a follow-up visit to assess the mid-term outcome. The Böhler's and Gissane's angles, the American Orthopaedic Foot & Ankle Society hindfoot score, the Maryland foot score and a visual analog scale for pain were measured preoperatively and postoperatively and after at least 6 years to assess the radiological and functional outcome.</p><p><strong>Results: </strong>Of the patients 59 completed the study with a mean follow-up of 76 months after surgery. The mean American Orthopedic Foot and Ankle Society hindfoot score at the last follow-up visit was 81, the mean Maryland foot score was 78. There were three cases (5%) of superficial wound complications and secondary arthrodesis of the subtalar joint was performed in five patients (8%).</p><p><strong>Conclusion: </strong>The low rates of postoperative infections and secondary arthrodesis in this study underline the good to excellent mid-term functional results for a minimally invasive technique.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"544-550"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12446096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrence of sexually transmitted infections is commonly found in a subpopulation of Austrian users of HIV pre-exposure prophylaxis.","authors":"Nikolaus Urban, Thomas Neidhart, Katharina Grabmeier-Pfistershammer, Veronique Touzeau-Roemer, Kaspar Laurenz Schmidt, Robert Strassl, Wolfgang Weninger, Birgit Willinger, Wolfgang Michael Bauer, David Chromy","doi":"10.1007/s00508-025-02499-6","DOIUrl":"10.1007/s00508-025-02499-6","url":null,"abstract":"<p><strong>Background: </strong>In recent years there has been an increase in the diagnoses of sexually transmitted infections (STI) among men who have sex with men (MSM) using human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP); however, data on PrEP users in Austria are limited.</p><p><strong>Patients, material and methods: </strong>In June 2020, we initiated a prospective observational cohort study at Vienna General Hospital including PrEP users from Vienna. Participants underwent STI testing quarterly and provided behavioral information using a questionnaire.</p><p><strong>Results: </strong>Between June 2020 and December 2023 a total of 360 individuals (99% MSM) were enrolled comprising 379 person-years of follow-up. We identified 276 STIs in 154 individuals, of which 23% (36/154) were symptomatic. The incidence rates per 100 person-years were 29.9 (95% confidence interval, CI 24.3-35.3 per 100 person-years) for gonorrhea, 22.7 (95% CI 17.9-27.5 per 100 person-years) for chlamydia and 9.8 (95% CI 6.6-12.9 per 100 person-years) for syphilis. Extragenital infections accounted for 95% (97/102) of gonorrhea and 81% (65/80) of chlamydia cases. A case of HIV infection was recorded in a 20-year-old male with inconsistent PrEP use. Participants with one or more reinfection (18%; 65/360) accounted for 68% (187/276) of all STIs. Sexualized drug use (Chemsex) was reported by 44% (157/360) of participants and was significantly associated with higher rates of gonorrhea (38% vs. 21%, p < 0.001) and syphilis (17% vs. 5%, p < 0.001) but not chlamydia (26% vs. 19%, p = 0.118).</p><p><strong>Conclusion: </strong>Throughout the study, 43% of participants experienced a bacterial STI, which was mostly asymptomatic and at extragenital sites. Chemsex was commonly reported and identified as a predictor for STI reinfection, underlining the importance of harm reduction strategies in Austrian STI prevention.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"571-578"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12446104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: comment on \"Acute liver failure in patients admitted to the intensive care unit-A Viennese retrospective single-center analysis\".","authors":"Patrick Haselwanter, Mathias Schneeweiss-Gleixner","doi":"10.1007/s00508-025-02600-z","DOIUrl":"https://doi.org/10.1007/s00508-025-02600-z","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transient global amnesia with bilateral punctate hippocampal hyperintensities on diffusion-weighted imaging.","authors":"Jie-Qiang Xia, Xue Ke, Hao Sun","doi":"10.1007/s00508-025-02602-x","DOIUrl":"https://doi.org/10.1007/s00508-025-02602-x","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of nosocomial infection in the intensive care unit of Ghazi Al-Hariri teaching hospital.","authors":"Waleed Ibraheem Ali, Layla Ali Hakeem, Zainab Taha Mohammed, Hayder Adnan Fawzi","doi":"10.1007/s00508-025-02598-4","DOIUrl":"https://doi.org/10.1007/s00508-025-02598-4","url":null,"abstract":"<p><strong>Background: </strong>Nosocomial infections have a significant impact on patients and the healthcare system. These infections lead to severe illness and mortality, prolonged hospitalization, reduced quality of life, and elevated healthcare costs.</p><p><strong>Aim: </strong>To assess and analyze the incidence and characteristics of nosocomial infections in the intensive care unit (ICU) of Ghazi Al-Hariri Hospital, categorize the types of nosocomial infections prevalent in the ICU, and investigate temporal trends in the incidence of nosocomial infections within the ICU.</p><p><strong>Methods: </strong>A prospective cohort study was conducted, collecting information from patients regarding their basic demographic characteristics and clinical features, including the APACHE II score, degree of organ dysfunctions, type of infection, and all procedures performed during patient care within the ICU.</p><p><strong>Results: </strong>Of the patients 40.2% developed nosocomial infections; most were male (58%), aged under 60 years (56%), with a mean age of 54.6 ± 18.7 years. The median ICU stay was 16 days (range: 8-125 days), and the mortality rate was 60%. Medical conditions led to 68% of ICU admissions. The APACHE II scores indicated most patients were in class V (56%) and class III (24%). Ventilator-associated pneumonia (VAP) was the most common infection (64%), with Acinetobacter baumannii the most prevalent (31%). In patients with nosocomial infection, the following predictors are associated with an increased risk of death: higher APACHE 2 score, increased number of organ dysfunctions, higher SOFA (Sequential Organ Failure Assessment) score, and high CRP (C-reactive protein) levels.</p><p><strong>Conclusion: </strong>The prevalence of nosocomial infections was high and was associated with a higher mortality rate. Furthermore, a higher APACHE 2 score, an increased number of organ dysfunctions, a higher SOFA score, and high CRP levels were the most important predictors of mortality.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arterial stiffness in women with gestational diabetes mellitus in pregnancy and postpartum.","authors":"Ana Dugandžić Šimić, Vedrana Mandrapa, Ana Bošković, Tanja Krešić, Goran Šimić, Vajdana Tomić","doi":"10.1007/s00508-025-02581-z","DOIUrl":"https://doi.org/10.1007/s00508-025-02581-z","url":null,"abstract":"<p><p>Gestational diabetes mellitus (GDM) is associated with various maternal and fetal complications, including long-term cardiovascular risks for affected women. This study aimed to investigate the relationship between GDM and arterial stiffness during pregnancy and 2 months postpartum. A cross-sectional study was conducted with 100 pregnant women of 28-40 weeks of gestation and divided into 2 groups. The groups were divided based on oral glucose tolerance test (oGTT) results: 50 women with GDM and 50 controls with normal oGTT. All participants in the GDM group had a form of GDM that was successfully managed by diet only. Arterial stiffness was assessed using a non-invasive oscillometric device, the Arteriograph® (TensioMed^TM Kft, Budapest, Hungary), by measuring the right brachial artery. The results showed that during pregnancy the pulse wave velocity (PWV) was unexpectedly significantly lower in the GDM group compared to controls (8.10 m/s vs. 8.65 m/s, P T< 0.05). Central and brachial augmentation index (AIx) values showed no significant differences between the groups. No differences in PWV or AIx were observed between GDM and control groups 2 months postpartum; however, within the GDM group, central (0.50 % vs. 11.45 %) and brachial (-73.35 % vs. -51.75 %) AIx significantly increased after delivery, indicating postpartum vascular effects of GDM.These findings suggest that even diet-managed forms of GDM can induce vascular changes postpartum, underscoring the importance of early detection and management. Further research is needed to explore the mechanisms underlying these changes and their possible long-term implications for cardiovascular health in post-GDM women.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Balancing innovation and interpretation: evaluating artificial intelligence in adenoma detection : AI and adenoma detection: benefits and boundaries.","authors":"Nathkapach Kaewpitoon Rattanapitoon, Phatsakul Thitimahatthanakusol, Thirayu Meererksom, Schawanya Kaewpitoon Rattanapitoon","doi":"10.1007/s00508-025-02599-3","DOIUrl":"10.1007/s00508-025-02599-3","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"The impact of artificial intelligence on the adenoma detection rate\".","authors":"Mohsin Ali, Habib Ullah, Manahil Noor, Ameer Afzal Khan, Rahman Syed","doi":"10.1007/s00508-025-02604-9","DOIUrl":"https://doi.org/10.1007/s00508-025-02604-9","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Acute liver failure in patients admitted to the intensive care unit-A viennese retrospective single-center analysis\".","authors":"Mohsin Ali, Ameer Afzal Khan, Rahman Syed, Manahil Noor, Bilal Ahmad","doi":"10.1007/s00508-025-02594-8","DOIUrl":"10.1007/s00508-025-02594-8","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}