Zeitschrift fur Geburtshilfe und Neonatologie最新文献

{"title":"Delayed Pelvic Abscess After Cesarean Section Successfully Treated with Laparoscopic Excision: A case Report.","authors":"Irem Herguner, Melik Kaan Bengi, Taylan Onat","doi":"10.1055/a-2859-1125","DOIUrl":"10.1055/a-2859-1125","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"452-454"},"PeriodicalIF":0.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between pregnant women's traumatic birth perceptions and birth beliefs and prenatal attachment.","authors":"Kevser Altuner, Seyhan Çankaya","doi":"10.1055/a-2872-5039","DOIUrl":"10.1055/a-2872-5039","url":null,"abstract":"<p><strong>Background and aims: </strong>Traumatic perceptions of childbirth and beliefs about the birth process may influence the emotional bond formed between a mother and her unborn baby. This study aimed to examine the relationships between traumatic birth perception, birth beliefs, and prenatal attachment in pregnant women.</p><p><strong>Methods: </strong>This descriptive and correlational study was conducted between December 2024 and June 2025 in the antenatal outpatient clinic of a hospital located in the Central Anatolia region of Türkiye. A total of 390 pregnant individuals who attended the clinic during the study period were included. Data were collected using a Personal Information Form, the Traumatic Childbirth Perception Scale (TCPS), the Birth Beliefs Scale (BBS), and the Maternal Antenatal Attachment Scale (MAAS).</p><p><strong>Results: </strong>The participants had a mean age of 24.23±3.70 years, and most were in the third trimester of pregnancy (72.6%). Overall, participants reported moderate levels of traumatic childbirth perception and relatively high prenatal attachment. Correlation analyses indicated a statistically significant but small negative association between traumatic childbirth perception and prenatal attachment (r=-0.155, p<0.01). Prenatal attachment was also positively associated with beliefs that conceptualize childbirth as a natural process; however, this relationship was likewise small in magnitude (rₛ=0.103, p<0.05). Multiple regression analysis further showed that traumatic childbirth perception was a significant but small negative predictor of prenatal attachment (β=-0.157, p<0.01).</p><p><strong>Conclusion: </strong>Traumatic childbirth perception was inversely associated with prenatal attachment, whereas beliefs that conceptualize childbirth as a natural process were positively associated with prenatal attachment. The findings suggest that addressing traumatic childbirth perceptions and supporting positive childbirth beliefs may be relevant considerations in antenatal care practices aimed at promoting prenatal attachment.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"439-448"},"PeriodicalIF":0.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148212884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal Neonatal-Onset Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency Caused by a Novel Homozygous HADHA Variant: A Case Report.","authors":"Batuhan Yeke, Hayriye Gözde Kanmaz Kutman, Şerife Suna Oğuz, Serdar Ceylaner, Ayşenur Engin Erdal, Berrak Bilginer Gürbüz","doi":"10.1055/a-2956-5297","DOIUrl":"https://doi.org/10.1055/a-2956-5297","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149064845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid Disorders during Pregnancy and Puerperal Periods: A Narrative Review.","authors":"Gabriela Letícia Corrêa Souza Oliveira, Julia Crocomo Tozzi, Paula Andregheto, Gustavo Yano Callado, Edward Araujo Júnior, Antonio Braga, Eduardo Felix Martins Santana","doi":"10.1055/a-2956-4381","DOIUrl":"10.1055/a-2956-4381","url":null,"abstract":"<p><strong>Objectives: </strong>Thyroid disorders are among the most clinically relevant endocrine conditions during pregnancy and the puerperal period. Given their clinical importance, this article aims to contextualize the role of thyroid dysfunction, particularly subclinical hypothyroidism, during these periods and to analyze the ongoing debate regarding screening and treatment based on international guideline recommendations.</p><p><strong>Methods: </strong>This narrative literature review was conducted using the SciELO, PubMed/MEDLINE, Embase, UpToDate, and Virtual Health Library databases. In addition, official documents from the Brazilian Ministry of Health, the Brazilian Society of Endocrinology and Metabolism, the Brazilian Federation of Gynecology and Obstetrics Associations, the American Thyroid Association, the European Thyroid Association, the American College of Obstetricians and Gynecologists, and the Brazilian Association of Medical Education were reviewed.</p><p><strong>Results: </strong>Thyroid disorders during pregnancy pose a clinical challenge due to physiological gestational changes, variability in thyroid-stimulating hormone and thyroxine reference ranges, and the influence of thyroid autoimmunity. Diagnostic definition is hindered by the lack of uniform laboratory reference intervals, contributing to overdiagnosis and unnecessary treatment. Evidence indicates that the benefit of levothyroxine therapy is mainly observed when the maternal thyroid-stimulating hormone level exceeds 4.0 mU/L and treatment is initiated early in pregnancy. In the postpartum period, the risk of persistent thyroid dysfunction highlights the importance of hormonal reassessment and individualized, evidence-based decision-making that accounts for population-specific factors.</p><p><strong>Conclusion: </strong>There is no clear consensus in the literature regarding the diagnosis and management of thyroid disorders during the pregnancy-puerperal cycle. Therefore, screening and care strategies should be expanded and adapted to local contexts in order to optimize maternal and fetal outcomes, while respecting regional epidemiological and laboratory characteristics.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149040959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Umbilical and Middle Cerebral Artery Pulsatility Indices as Predictors of a Nuchal Cord: A Retrospective Cohort Study.","authors":"Laura Beatriz Carvalho Oliveira, Luisa Fernandes Andrade, Gustavo Yano Callado, Anna Moreira Herval, Clara Trajano Borges, Eduardo Moreira Nader, Antonio Braga, Edward Araujo Júnior, Alberto Borges Peixoto","doi":"10.1055/a-2956-6022","DOIUrl":"10.1055/a-2956-6022","url":null,"abstract":"<p><strong>Objective: </strong>This retrospective cohort study aimed to evaluate the impact of a nuchal cord at birth on the pulsatility indices of the umbilical artery, the middle cerebral artery, and the cerebroplacental ratio, assessed by Doppler ultrasound within 7 days before delivery. Secondary objectives included assessing the associations between the presence of a nuchal cord and a tight nuchal cord with adverse neonatal outcomes, as well as the correlations between the number of cord loops and Doppler indices and umbilical cord blood gas values.</p><p><strong>Methods: </strong>Data from 203 singleton pregnancies with Doppler ultrasound performed within 7 days before delivery were analyzed. Participants were grouped according to the presence or absence of nuchal cord at birth. Doppler parameters (umbilical artery pulsatility index, middle cerebral artery pulsatility index, and cerebroplacental ratio) and clinical variables, including arterial and venous umbilical cord blood pH, Apgar scores, birth weight, and adverse perinatal events, were evaluated.</p><p><strong>Results: </strong>The presence of a nuchal cord or a tight nuchal cord at birth did not affect the Doppler parameters in obstetric ultrasound examinations conducted up to 7 days prior to delivery. The presence of a nuchal cord was not significantly associated with adverse perinatal outcomes. A weak but statistically significant positive correlation was observed between the number of cord loops and the middle cerebral artery pulsatility index, with no significant correlation with the umbilical artery pulsatility index, cerebroplacental ratio, or umbilical cord blood pH values.</p><p><strong>Conclusion: </strong>These findings suggest that the presence of a nuchal cord does not impact the pulsatility index of the umbilical artery, middle cerebral artery, and cerebroplacental ratio, assessed by Doppler ultrasound within 7 days before delivery. Further research is needed to clarify the clinical implications.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149031598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Oxidative Phosphorylation Deficiency 12 Spectrum in a Neonate with a Homozygous EARS2 Variant: Critical Aortic Stenosis and Refractory Supraventricular Tachycardia.","authors":"Hasan Akduman, Canan Atak, Utku Arman Örün, Haktan Bağış Erdem, Abdulkerim Kolkıran","doi":"10.1055/a-2958-2543","DOIUrl":"https://doi.org/10.1055/a-2958-2543","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149031615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternales Klippel-Trénaunay-Weber-Syndrom.","authors":"Arne Bringewatt, Stephan Henschen, Wolfgang Henrich","doi":"10.1055/a-2915-6945","DOIUrl":"https://doi.org/10.1055/a-2915-6945","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148983555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Cathepsin D Levels in Pregnant Women with Gestational Diabetes Mellitus: A Case-Control Study.","authors":"Umut Çağrı Gonca, Metehan Hergüner, Doğuş Budak, İbrahim Kale","doi":"10.1055/a-2942-5811","DOIUrl":"https://doi.org/10.1055/a-2942-5811","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate maternal serum cathepsin D (CTSD) levels in pregnancies complicated by gestational diabetes mellitus (GDM) and to investigate the association between CTSD, glycemic parameters, and perinatal outcomes. Additionally, the diagnostic performance of CTSD in predicting GDM was assessed.</p><p><strong>Materials and methods: </strong>In this prospective cross-sectional case-control study, 88 pregnant women at 24-28 weeks of gestation were enrolled, comprising 44 women with GDM and 44 age-, body mass index (BMI-), and gestational age-matched healthy controls. GDM was diagnosed using a 75-g oral glucose tolerance test (OGTT) according to IADPSG criteria. Fasting peripheral venous blood samples were collected to measure serum CTSD levels via enzyme-linked immunosorbent assay (ELISA). Clinical, biochemical, and perinatal data were recorded. Comparisons between groups were performed using Student's t-test or Mann-Whitney U test, and correlations were evaluated using Spearman analysis. Receiver operating characteristic (ROC) curve analysis was conducted to assess the predictive value of CTSD for GDM.</p><p><strong>Results: </strong>The two groups were comparable in terms of maternal age, BMI, gestational weight gain, parity, and gestational age at sampling. Serum CTSD levels were significantly lower in the GDM group than in controls (10.1 vs. 15.1 ng/mL; p=0.004). ROC analysis revealed a CTSD cut-off value of 10.2 ng/mL, yielding 52.3% sensitivity, 93.2% specificity, and an area under the curve of 0.677. Serum CTSD levels were negatively correlated with 2-hour OGTT glucose and HbA1c (r=- 0.257 and -0.256; p=0.016 for both).</p><p><strong>Conclusion: </strong>Maternal serum CTSD levels are reduced in pregnancies complicated by GDM and are associated with glycemic control, suggesting that CTSD may serve as a potential biomarker reflecting inflammation-related metabolic alterations during pregnancy. Further prospective studies are warranted to clarify the predictive and clinical utility of CTSD in the management of GDM.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148931489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uteroplacental Hemodynamics and Perinatal Outcomes in Maternal Hypothyroidism and Thyroid Autoimmunity: A Prospective Cohort Study.","authors":"Raziye Torun, Hakan Golbasi, Sevim Tuncer Can, Mukremin Ceylan, Mustafa Şengül, Atalay Ekin","doi":"10.1055/a-2940-2354","DOIUrl":"10.1055/a-2940-2354","url":null,"abstract":"<p><strong>Background: </strong>Maternal hypothyroidism and thyroid autoimmunity are frequently implicated in compromised uteroplacental perfusion and subsequent adverse perinatal outcomes. However, the incremental risk conferred by thyroid antibody positivity beyond that of hypothyroidism alone remains a subject of clinical debate.</p><p><strong>Objective: </strong>To examine uteroplacental hemodynamics, via uterine artery (UtA) and umbilical artery (UA) Doppler, and their relation to perinatal outcomes in pregnancies complicated by hypothyroidism with or without thyroid antibodies.</p><p><strong>Methods: </strong>This prospective cohort study, conducted at a tertiary perinatology center between August 2024 and April 2025, enrolled 212 pregnant women (18-24 weeks' gestation) into three groups: (1) hypothyroidism with thyroid antibodies [TPOAb/TGAb] on levothyroxine (n=72); (2) hypothyroidism without antibodies [first-trimester TSH>2.5 mIU/L] on levothyroxine (n=71); and (3) a control group (n=69). Standardized transabdominal UA and bilateral UtA Doppler assessments (S/D ratio, pulsatility index [PI]) were performed according to ISUOG guidelines. Comprehensive perinatal outcomes, including obstetric complications and neonatal status, were recorded.</p><p><strong>Results: </strong>While BMI was significantly lower in the control group (p=0.008), fetal biometry and birth outcomes remained comparable across all cohorts. Paradoxically, mean UtA PI was significantly higher in controls than in both hypothyroid groups (p<0.001), whereas other Doppler parameters showed no significant differences. The overall obstetric complication rate was 41%, with no statistical variation between groups (p=0.999). Similarly, NICU admission and congenital hypothyroidism rates did not differ significantly.</p><p><strong>Conclusions: </strong>In this treated, single-center cohort, well-managed maternal hypothyroidism and thyroid autoimmunity were not associated with increased uteroplacental Doppler abnormalities or worse perinatal outcomes compared to controls. These findings suggest that timely and appropriate levothyroxine therapy may successfully mitigate the potential adverse hemodynamic impacts of thyroid dysfunction, though larger multicenter trials are needed to isolate the specific role of autoimmunity.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive fetomaternale Transfusion bei bekannter Anti-C(w)-Alloimmunisierung: differenzialdiagnostische Herausforderungen bei schwerer fetaler Anämie.","authors":"Jelena Dimitrijevic, Nicole Holzgartner, Susanne Rauber, Julia Knabl, Sven Kehl, Christina Kouskouti","doi":"10.1055/a-2926-4975","DOIUrl":"https://doi.org/10.1055/a-2926-4975","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}