Zeitschrift fur Geburtshilfe und Neonatologie最新文献

{"title":"Postpartales Cogan-Syndrom als Komplikation nach Chitosan Tamponaden Einlage – Eine Fallserie mit Beleuchtung der unerwünschten Ereignisse.","authors":"Melanie Wilmes, Anna Lentzsch, Kariem Sharaf, Katrin Löw, Florian Steinberg, Lebriz Altay, Tobias Münster, Johannes Strunk, Hirotsugu Oda, Jens Peter Klußmann, Claus Cursiefen, Tanja Groten","doi":"10.1055/a-2926-4845","DOIUrl":"https://doi.org/10.1055/a-2926-4845","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PFIC Type 4 Presenting As Biliary Atresia-like Neonatal Cholestasis: a Case With Persistent Truncus Arteriosus and Horseshoe Kidney.","authors":"Hasan Akduman, Yağmur Diri Asar, Mehmet Ali Kara, Özkan Kaya, Melike Ataseven Kulalı, Aslan Yılmaz","doi":"10.1055/a-2924-4856","DOIUrl":"https://doi.org/10.1055/a-2924-4856","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148689932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Stroke and Cerebral Sinovenous Thrombosis in the Newborn (S2k-Leitlinie, AWMF-Register-Nr. 024-024, Version 1.0)].","authors":"Mark Dzietko, Katrin Klebermass-Schrehof, Gabriele Hahn, Hans-Joachim Mentzel, Lucia Gerstl, Amr Sherif Hamza, Susanne Holzhauer, Ronald Straeter, Anja Gehlken","doi":"10.1055/a-2876-5739","DOIUrl":"10.1055/a-2876-5739","url":null,"abstract":"<p><strong>Background: </strong>Neonatal stroke is a rare but clinically significant neurological disorder associated with substantial morbidity and potentially severe long-term sequelae. Despite advances in diagnostic techniques, uncertainties remain regarding diagnosis, treatment, and follow-up care. The aim of this S2k guideline is to provide evidence- and consensus-based recommendations for the standardized management of neonates with arterial ischemic stroke, hemorrhagic stroke, and cerebral sinovenous thrombosis (CSVT).</p><p><strong>Methods: </strong>The guideline was developed through a structured S2k consensus process involving multidisciplinary professional societies and experts. Recommendations were based on a systematic review of the available literature and a formal consensus procedure to establish diagnostic and therapeutic guidance.</p><p><strong>Results: </strong>The guideline defines neonatal stroke as the acute onset of neurological symptoms within the first 28 days of life associated with a cerebrovascular event confirmed by magnetic resonance imaging (MRI). Given the frequently nonspecific clinical presentation, particularly seizures, apnea, and altered consciousness, prompt diagnostic evaluation is recommended. Initial neuroimaging should consist of transfontanellar cranial ultrasonography including Doppler assessment, followed by MRI with diffusion-weighted imaging and vascular imaging, which represents the diagnostic gold standard. Computed tomography is not recommended because of radiation exposure and limited diagnostic sensitivity. Neonates with suspected stroke or seizures should undergo continuous neurophysiological monitoring using bilateral amplitude-integrated electroencephalography (aEEG). Routine screening for inherited thrombophilia is not recommended in cases of arterial ischemic stroke. Supportive management aimed at maintaining normoxia, normocapnia, normothermia, and stable glucose homeostasis constitutes the cornerstone of treatment. In neonates with CSVT, acute anticoagulation therapy and, when appropriate, extended anticoagulation are recommended in the absence of contraindications. Routine antithrombotic therapy following arterial ischemic stroke is not recommended because of the low recurrence risk.</p><p><strong>Conclusions: </strong>This S2k guideline provides comprehensive recommendations for the diagnosis, treatment, and long-term management of neonatal stroke and CSVT. Early identification of affected infants, appropriate use of advanced neuroimaging, and structured interdisciplinary follow-up are essential to minimize neurological sequelae and improve long-term neurodevelopmental outcomes.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"276-290"},"PeriodicalIF":0.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of serum Agouti-related peptide levels in pregnant women with hyperemesis gravidarum.","authors":"Melek Erdoğan, Hande Esra Koca Yıldırım, İbrahim Kale","doi":"10.1055/a-2784-5204","DOIUrl":"10.1055/a-2784-5204","url":null,"abstract":"<p><strong>Objective: </strong>Agouti-related peptide (AgRP) is an orexigenic neuropeptide secreted by the hypothalamus that plays a key role in stimulating appetite and increasing food intake. This study aimed to evaluate circulating AgRP levels in pregnant women diagnosed with hyperemesis gravidarum (HG).</p><p><strong>Methods: </strong>This cross-sectional case-control study compared serum AgRP levels between two groups of pregnant women. The first group included 44 women aged 18-40 years who were hospitalized during the first trimester due to HG, while the control group consisted of 44 healthy pregnant women without HG, matched for age, body mass index (BMI), and gestational age.</p><p><strong>Results: </strong>Both groups were similar in terms of age, BMI, gravida, parity, and gestational week at which blood samples were taken (p > 0.05 for all). Median serum AgRP level was 211.67 ng/L in the HG group and 182.14 ng/L in the control group (p=0.073). There was a significant positive correlation between AgRP level and maternal BMI as well as urinary ketone positivity (r=0.326, r=0.334, r=0.536, r=0.335; p<0.05, respectively).</p><p><strong>Conclusion: </strong>In this study, serum AgRP levels did not differ significantly between the HG and control groups. Although these findings should be interpreted with caution due to the limited sample size, they suggest that AgRP may not play a central role in the pathogenesis of HG. Further prospective studies with larger cohorts are warranted to better elucidate this potential association.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"300-305"},"PeriodicalIF":0.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-occurrence of Acute Abdominal Distension and Massive Ascites Secondary to PICC Extravasation.","authors":"Chousein Amet, Kamil Değer Devecioğlu, Bilge Bayraktar Tanyeri","doi":"10.1055/a-2815-1480","DOIUrl":"10.1055/a-2815-1480","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"353-355"},"PeriodicalIF":0.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-contact monitoring of vital parameters in preterm infants: Insights from infrared thermography and photoplethysmography imaging.","authors":"Milian Brasche, Markus Lüken, Steffen Leonhardt, Thorsten Orlikowsky, Konrad Heimann","doi":"10.1055/a-2826-4049","DOIUrl":"10.1055/a-2826-4049","url":null,"abstract":"<p><strong>Background: </strong>Preterm infants are particularly burdened by wired monitoring systems. Contactless methods such as infrared thermography (IRT) and photoplethysmography imaging (PPGI) may offer a less invasive alternative. This study presents the feasibility and iterative development of these techniques during routine neonatal care.</p><p><strong>Methods: </strong>IRT was used to assess respiratory activity and skin temperature across various care settings (incubator, kangaroo care, heated bed) from 2011 to 2023. PPGI was applied between 2016 and 2021 to measure cardiac activity and perfusion, accompanied by technical refinement. Accuracy was evaluated through comparative studies using established reference standards, including ECG.</p><p><strong>Results: </strong>Both IRT and PPGI reliably detected respiratory rate, skin temperature (including stress-related facial changes), cardiac activity, and perfusion in preterm infants.</p><p><strong>Conclusion: </strong>Advances in sensor miniaturization and data processing suggest that, following further prospective evaluation, contactless vital sign monitoring could be feasibly integrated into routine neonatal care.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"323-329"},"PeriodicalIF":0.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary Alveolar Microlithiasis in Pregnancy: A Case Report and Review of the Literature.","authors":"İbrahim Kale, Mehtap Yücedağ, Ahmet Zengin","doi":"10.1055/a-2825-7326","DOIUrl":"10.1055/a-2825-7326","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"349-352"},"PeriodicalIF":0.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seeing the Unseen: The Power of Ultrasound in Neonatal Catheter Malposition.","authors":"Buse Onen Ocak, Şeyma Bütün Türk, Ömer Ertekin, Gülmelek Duranoğlu, Gökcen Meral, Davut Bozkaya, Serife Suna Oguz","doi":"10.1055/a-2792-1792","DOIUrl":"10.1055/a-2792-1792","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"356-358"},"PeriodicalIF":0.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147436221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatalmedizin verbindet – Wissenschaft gemeinsam gestalten.","authors":"Sven Kehl","doi":"10.1055/a-2884-2296","DOIUrl":"https://doi.org/10.1055/a-2884-2296","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":"230 4","pages":"269"},"PeriodicalIF":0.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Thyroid Disorders during Pregnancy and Puerperal Periods: A Narrative Review.","authors":"Gabriela Letícia Corrêa Souza Oliveira, Julia Crocomo Tozzi, Paula Andregheto, Gustavo Yano Callado, Edward Araujo Júnior, Antonio Braga, Eduardo Félix Martins Santana","doi":"10.1055/a-2970-7539","DOIUrl":"https://doi.org/10.1055/a-2970-7539","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":"230 4","pages":"e2"},"PeriodicalIF":0.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}