{"title":"Resuscitation of newborn infants and postnatal support of transition - An overview of the European Resuscitation Council guideline 2025.","authors":"Lukas Peter Mileder, Michael Wagner","doi":"10.1055/a-2847-3068","DOIUrl":"https://doi.org/10.1055/a-2847-3068","url":null,"abstract":"<p><strong>Abstract: </strong>In October 2025, the European Resuscitation Council published its latest practice guideline about \"Newborn Resuscitation and Support of Transition of Infants at Birth\". In this focused review, we summarize the most relevant elements of this guideline in a structured manner. For this purpose, we first outline the main aspects that remained unchanged from the 2021 guideline before focusing on the implemented modifications and changes.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Milian Brasche, Markus Lüken, Steffen Leonhardt, Thorsten Orlikowsky, Konrad Heimann
{"title":"For a better understanding of thermoregulation in premature infants≤28 weeks of gestation: infrared thermography (IRT) and photoplethysmography imaging (PPGI) in a hybrid camera model as non-contact measuring methods.","authors":"Milian Brasche, Markus Lüken, Steffen Leonhardt, Thorsten Orlikowsky, Konrad Heimann","doi":"10.1055/a-2840-5109","DOIUrl":"https://doi.org/10.1055/a-2840-5109","url":null,"abstract":"<p><strong>Background: </strong>Infrared thermography (IRT) reveals significant temperature differences between central and peripheral body regions in preterm infants, despite stable core temperature. This suggests active thermoregulation. Photoplethysmography imaging (PPGI) enables contactless, spatially resolved perfusion measurement.</p><p><strong>Methods: </strong>Ten preterm infants [GA at birth: 26 weeks (24-28); postnatal age: 35 days (12-62); weight: 960 g (670-1290)] were examined in prone (PR) and supine (SU) positions in the incubator. PPGI (amplitude) and IRT were recorded from arm, head, and thorax every 10 s for 5 min per position, with a 10 min washout. Heart rate (ECG) was monitored. Lin's concordance correlation coefficient was calculated.</p><p><strong>Results: </strong>Central regions were ~1°C warmer than peripheral regions (p<0.05), independent of position. PPGI amplitude remained constant (< 1.0; p>0.05) in all regions, with no correlation between IRT and PPGI (p>0.05).</p><p><strong>Conclusion: </strong>In preterm infants, local perfusion remains stable despite regional temperature differences, suggesting that skin temperature is influenced more by passive heat diffusion than by perfusion changes.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cornelia Hinz, Axel Heep, Torsten Plösch, André Homeyer, Matthias Lange
{"title":"Influence of odorants on preterm and term infants during neonatal intensive care: Overview and perspectives.","authors":"Cornelia Hinz, Axel Heep, Torsten Plösch, André Homeyer, Matthias Lange","doi":"10.1055/a-2844-5138","DOIUrl":"10.1055/a-2844-5138","url":null,"abstract":"<p><strong>Abstract: </strong>Olfactory cues play a crucial role in peri- and postnatal development and are thought to be involved in basic processes, like parent-child bonding or the establishment of the breastfeeding relationship. These processes are highly important for the physical and mental health of the developing child. However, little attention has been given to monitoring and maintaining the olfactory environment of preterm (PI) and term (TI) infants in the hospital. This environment differs fundamentally from that of healthy neonates because the patients are exposed to odors from clinical interventions while the natural olfactory input is limited. In this article, we summarize examples of how PI and TI respond to olfactory signals and how olfactory stimulation can positively influence feeding, stress, and pain management or even stabilize breathing. Although different studies have investigated the positive effects of maternal odors and demonstrated that PI and TI respond highly sensitively and distinctly to them, hardly any comparable studies exist for paternal odors. Also, the knowledge about the role of other natural or artificial odorants is very sparse. Future work should focus on investigating the role of these odorants and on optimizing olfactory stimulation strategies using objective odor analysis techniques.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruth Denkhaus, Pia Göbert, Leonie Abstein, Daniela Reitz, Irene Hirschberg
{"title":"[Ethical Decision-Making in Late-Termination Requests: Recommendations for Developing In-Hospital Policies].","authors":"Ruth Denkhaus, Pia Göbert, Leonie Abstein, Daniela Reitz, Irene Hirschberg","doi":"10.1055/a-2843-8402","DOIUrl":"https://doi.org/10.1055/a-2843-8402","url":null,"abstract":"<p><strong>Background: </strong>Late terminations of pregnancy (after 14 weeks of gestation) can present physicians and other healthcare professionals with complex medical and ethical challenges. In Germany, such terminations require a specific form of medical indication (a danger of grave impairment to the pregnant woman's physical or mental health). Despite these legal provisions, the decision-making process in individual cases often remains characterized by uncertainty, a lack of transparency and insufficient structural support.</p><p><strong>Aim: </strong>This article offers recommendations for the development of institutional ethics guidelines that can support responsible, transparent, and legally sound decision-making in cases of requests for a late termination of pregnancy.</p><p><strong>Method: </strong>Based on existing recommendations and experience reports, and on the authors' own reflections, key challenges in decision-making are identified and practical guidance for shaping the decision-making process is derived.</p><p><strong>Results and implications: </strong>Ethical guidelines can help reduce uncertainty, foster interdisciplinary and ethically informed decision-making, and thereby contribute to improving patient care. This requires the development of clear procedures, defined responsibilities, and transparent decision-making frameworks, as well as the promotion of thoughtful engagement with diverse professional perspectives and individual values. The development and implementation of clinical ethics guidelines can offer meaningful structural support for treatment teams in responsibly managing (cases of) late termination of pregnancy.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First-trimester crown-rump length discordance as an early predictor of adverse neonatal outcomes in twin pregnancies.","authors":"Neval Çayönü Kahraman, Nazan Vanlı Tonyalı, Furkan Akın, Ali Turhan Çağlar","doi":"10.1055/a-2833-2273","DOIUrl":"10.1055/a-2833-2273","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the significance of crown-rump length (CRL) and nuchal translucency (NT) discordance assessed during the first trimester in twin pregnancies for predicting adverse neonatal outcomes, and to ascertain the relative importance of these parameters in comparison to birth weight (BW) discordance, which can be evaluated postnatally.</p><p><strong>Material and methods: </strong>A retrospective cohort study performed at a tertiary center from January 2024 to June 2025 encompassed 153 twin pregnancies, which had ultrasonographic assessments of CRL and NT at 11-14 weeks and followed up until delivery. Adverse neonatal outcome was characterized by BW discordance of≥20%, twin-to-twin transfusion syndrome (TTTS), selective fetal growth restriction (sFGR), intrauterine or perinatal mortality, or delivery prior to 32 weeks' gestation. Data were assessed using receiver operating characteristic (ROC) analysis and multivariable logistic regression.</p><p><strong>Results: </strong>The gestational week at delivery was markedly earlier in pregnancies with adverse neonatal outcomes (33 vs. 35 weeks, p<0.001). CRL discordance (8.2% vs. 3.4%; p<0.001), NT discordance (23.5% vs. 13.8%; p=0.045), and BW discordance (20.9% vs. 8.6%; p<0.001) were markedly elevated in this cohort. In ROC analysis, CRL discordance showed significant predictive value (area under the concentration (AUC) 0.753), BW discordance had a comparable strong value (AUC 0.770), however NT discordance displayed low predictive power (AUC 0.595). In multivariate analysis, a CRL discordance of≥11.6% was identified as an independent risk factor (odds ratio (OR) 6.43; p<0.001).</p><p><strong>Conclusion: </strong>CRL discordance identified in the first trimester of twin pregnancies serves as an early and independent indicator of adverse neonatal outcomes.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147646821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Milian Brasche, Markus Lüken, Steffen Leonhardt, Thorsten Orlikowsky, Konrad Heimann
{"title":"Non-contact monitoring of vital parameters in preterm infants: Insights from infrared thermography and photoplethysmography imaging.","authors":"Milian Brasche, Markus Lüken, Steffen Leonhardt, Thorsten Orlikowsky, Konrad Heimann","doi":"10.1055/a-2826-4049","DOIUrl":"10.1055/a-2826-4049","url":null,"abstract":"<p><strong>Background: </strong>Preterm infants are particularly burdened by wired monitoring systems. Contactless methods such as infrared thermography (IRT) and photoplethysmography imaging (PPGI) may offer a less invasive alternative. This study presents the feasibility and iterative development of these techniques during routine neonatal care.</p><p><strong>Methods: </strong>IRT was used to assess respiratory activity and skin temperature across various care settings (incubator, kangaroo care, heated bed) from 2011 to 2023. PPGI was applied between 2016 and 2021 to measure cardiac activity and perfusion, accompanied by technical refinement. Accuracy was evaluated through comparative studies using established reference standards, including ECG.</p><p><strong>Results: </strong>Both IRT and PPGI reliably detected respiratory rate, skin temperature (including stress-related facial changes), cardiac activity, and perfusion in preterm infants.</p><p><strong>Conclusion: </strong>Advances in sensor miniaturization and data processing suggest that, following further prospective evaluation, contactless vital sign monitoring could be feasibly integrated into routine neonatal care.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing the Influence of Shift Timing on Mortality Rates in <32-Week Preterm Infants.","authors":"Mustafa Senol Akin, Ufuk Cakir","doi":"10.1055/a-2830-7916","DOIUrl":"10.1055/a-2830-7916","url":null,"abstract":"<p><strong>Introduction: </strong>Quality of continuous patient care is crucial in neonatal intensive care units (NICUs). Staff numbers and intervention timings may vary with working hours, potentially affecting clinical outcomes. However, the effect of on- and off-duty hours on neonatal mortality remains unclear. This study examined the clinical data of deceased premature infants during these hours and assessed mortality frequency over time.</p><p><strong>Materials and methods: </strong>A retrospective cohort analysis was performed at a single institution, focusing on deceased infants born at ≤ 32 weeks' gestation (WG). The study classified patients based on their time of death using two methods: on-duty versus off-duty periods and three consecutive eight-hour shifts across the day.</p><p><strong>Results: </strong>Overall, 256 deceased premature infants (on-duty group: 66 (25.8%); off-duty group: 190 (74.2%)) were enrolled. The off-duty period lasted approximately three times longer than the on-duty period, with a corresponding three-fold increase in the mortality rate. During off-duty hours, the number of medical doctors was 4.5 times fewer than that during on-duty hours. Nevertheless, mortality rates per unit time were comparable between the groups. Additionally, the clinical characteristics and morbidities of patients across the groups exhibited similar profiles.</p><p><strong>Conclusion: </strong>Despite a 4.5-fold decrease in physicians working during off-duty hours in our NICU, the mortality and morbidity rates for infants born at or before 32 WG remained unchanged.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}