{"title":"Leserbrief zu: Schichterfüllungsquoten in der Pflege und Überlebenschancen sehr kleiner Frühgeborener – Datenanalyse der Perinatalzentren Level 1 in Deutschland 2019–2023.","authors":"Ulrich H Thome","doi":"10.1055/a-2684-4978","DOIUrl":"https://doi.org/10.1055/a-2684-4978","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":"229 5","pages":"379"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurdan Dinlen Fettah, Seda Kunt, Meryem Sağır, Çağnay Soysal
{"title":"Anti-TPO-Negative Subclinical Hypothyroidism in the First Trimester and Its Influences on Obstetric and Neonatal Outcomes.","authors":"Nurdan Dinlen Fettah, Seda Kunt, Meryem Sağır, Çağnay Soysal","doi":"10.1055/a-2564-0905","DOIUrl":"10.1055/a-2564-0905","url":null,"abstract":"<p><p>The aim of this study was to assess the relationship between maternal anti-thyroid peroxidase (anti-TPO)-negative subclinical hypothyroidism (SCH) in the first trimester with complications of pregnancy and neonatal outcomes.The study was done at a maternity and children's research training hospital. First-trimester thyroid function tests (TFTs) (free thyroxine (FT4), thyroid stimulating hormone (TSH), anti-TPO) were checked for mothers who gave birth at the center, and their newborns were accepted for the study. Based on the results of the TFTs, two groups were formed, the normal thyroid function (euthyroid) and SCH groups. The neonatal and maternal outcomes were noted. This study included 150 mothers, of whom 110 (73.3%) had normal thyroid function and 40 (26.7%) had anti-TPO-negative subclinical hypothyroidism (SCH). Based on thyroid function tests (TSH: 0.1-4.0 mIU/L, FT4: 0.7-1.8 ng/dL), significant differences in pregnancy complications wereobserved, with higher rates of placental abruption, preeclampsia, and postpartum hemorrhage in the SCH group (p<0.001). Neonatal outcomes in the SCH group showed significantly higher rates of small for gestational age (SGA) (52.5%), NICU admission (77.5%), low Apgar score (52.5%), and transient tachypnea of the newborn (TTN) (67.5%) (all p<0.001). Logistic regression analysis identified SCH as a significant risk factor for TTN (OR=7.24; 95% CI: 3-17; p<0.001), while no significant associations were found with gestational age (p=0.194) or maternal age (p=0.600). Anti-TPO-negative SCH in pregnancy has undesirable effects, not only during pregnancy but also in siblings, and surprisingly, it may be a risk factor for TTN.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"350-354"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simon Nwakor, Konrad Reinshagen, Joachim Suß, Julian Jürgens, Katharina Wenke, Christian Tomuschat
{"title":"Congenital gastric duplication cyst: A case report of a 36 day-old girl.","authors":"Simon Nwakor, Konrad Reinshagen, Joachim Suß, Julian Jürgens, Katharina Wenke, Christian Tomuschat","doi":"10.1055/a-2563-1133","DOIUrl":"10.1055/a-2563-1133","url":null,"abstract":"<p><p>Duplications of the gastrointestinal tract exist in various forms and present differently depending on their location. They are extremely rare congenital malformations, and especially duplication cysts of the pyloric channel are among the rarest. They appear with a variety of symptoms, above all with severe vomiting. To date a surgical resection seems to be the only effective treatment. In order to share our experience with a congenital gastric duplication cyst, we present the case of a 36-day-old girl.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"376-378"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gerhard Pichler, Mathias Klemme, Michael Schroth, Andreas Trotter, Harald Abele, Silke Mader
{"title":"Neugeborenen-Transport (Leitlinienklasse S2k, AWMF-Leitlinien-Register Nr. 024/003).","authors":"Gerhard Pichler, Mathias Klemme, Michael Schroth, Andreas Trotter, Harald Abele, Silke Mader","doi":"10.1055/a-2678-2713","DOIUrl":"https://doi.org/10.1055/a-2678-2713","url":null,"abstract":"","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":"229 5","pages":"321-330"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Janik Wolff, Christian Batzlsperger, Christian Brickmann, Peter Dahlem, Heinrich Eberhardt, Fabian Fahlbusch, Andreas Fiedler, Eric Frieauff, Christoph Fusch, Oliver Jens Götz, Christoph Härtel, Matthias Hermann, Arni Kirchner, Jens Klinge, Katja Knab, Hans-Martin Lode, Patrick Morhart, Jochen Peters, Winfried Rauch, Andreas Reisig, Heiko Reutter, Michael Andreas Schroth, Gerald Staudacher, Marie-Therese Unterweger, Thomas Völkl, Sven Matthias Wellmann
{"title":"[Development of a standardized handover for critically ill premature and newborn infants for interhospital transport in Bavaria].","authors":"Janik Wolff, Christian Batzlsperger, Christian Brickmann, Peter Dahlem, Heinrich Eberhardt, Fabian Fahlbusch, Andreas Fiedler, Eric Frieauff, Christoph Fusch, Oliver Jens Götz, Christoph Härtel, Matthias Hermann, Arni Kirchner, Jens Klinge, Katja Knab, Hans-Martin Lode, Patrick Morhart, Jochen Peters, Winfried Rauch, Andreas Reisig, Heiko Reutter, Michael Andreas Schroth, Gerald Staudacher, Marie-Therese Unterweger, Thomas Völkl, Sven Matthias Wellmann","doi":"10.1055/a-2659-7541","DOIUrl":"10.1055/a-2659-7541","url":null,"abstract":"<p><p>A well-structured medical handover is crucial in many respects. Despite the enormous importance of a complete transfer of information, no comprehensive, standardized procedure exists. This study aims to analyze the currently available protocols for handover in Bavarian level 1 neonatology units and to summarize them in a standardized handover form.A multicenter analysis of 20 level 1 neonatology units in Bavaria was carried out. Fourteen handover forms were analyzed and examined for similarities. After creating a new form with the greatest possible overlap, this was mirrored back in two Delphi surveys by the participating clinics and adapted accordingly.By analyzing 14 forms, exactly 100 parameters were identified. For the design of the new sheet, all the parameters were considered with the greatest possible overlap. This resulted in a newly structured handover sheet.The newly structured handover form represents the intersection of parameters that were considered essential by the participating Bavarian level 1 neonatology units. The next step is to test the usability of the new form.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"331-337"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clara Illi, Lars Hellmeyer, Elena Groening, Josefine Königbauer, Julia Kummer, Charlotte Reinhardt, Paul Rostin
{"title":"Overweight and obesity in pregnancy - a retrospective cohort study in Germany.","authors":"Clara Illi, Lars Hellmeyer, Elena Groening, Josefine Königbauer, Julia Kummer, Charlotte Reinhardt, Paul Rostin","doi":"10.1055/a-2607-8668","DOIUrl":"10.1055/a-2607-8668","url":null,"abstract":"<p><p>Overweight and obesity are common among women of reproductive age. 43.8% of women in Germany and 50% of women in the US entering their pregnancy have a body mass index (BMI)≥25. Studies indicate that gestational overweight is associated with maternal and neonatal complications.2034 women from 2015 until 2018 were included. Trends in BMI, gestational weight gain, pregnancy outcome, complications, neonatal weight, and outcome were analyzed. Gestational weight gain was evaluated according to the Institute of Medicine (IOM) guidelines. 34% of the population were overweight with a BMI≥25. The overall weight gain was similar across BMI groups (median 11.0-14.0 kg). 44.1% gained more than recommended. These women were at higher risk of labor induction (33.1% vs. 27.0%, p=0.003), unplanned cesarean section (18.6% vs. 13.6%, p=0.004), lower incidence of spontaneous vaginal birth (54.5% vs. 59.9%, p=0.009), and higher neonatal birth weight (>90<sup>th</sup> percentile, 14.5% vs. 5.7%, p<0.001). Gestational diabetes was linked to a lower gestational weight gain (odds ratio 0.92, confidence interval 0.90-0.95, p<0.001).One third of the analyzed population was already overweight or obese at the beginning of the pregnancy. In 44.1% of cases, weight gain during pregnancy exceeded the recommended amount. This was associated with complications in pregnancy and labor as well as higher neonatal birth weight. This study highlights the importance of prenatal counseling and intervention on BMI and weight gain.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"355-362"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Annular Migratory Rash In a Newborn Related to Prostaglandin E1 Infusion: A Case Report.","authors":"Buse Önen Ocak, Refika Sirma Dokuzboy, Hayriye Gözde Kanmaz Kutman","doi":"10.1055/a-2615-1248","DOIUrl":"10.1055/a-2615-1248","url":null,"abstract":"<p><p>Prostaglandin E1 (PGE1, alprostadil) is essential in managing ductus-dependent congenital heart defects (CHD) in neonates. Although its common adverse effects are well documented, dermatologic manifestations remain rare and underrecognized. We report a term male neonate with a prenatal diagnosis of complex critical CHD who required PGE1 infusion and subsequently developed an annular migratory rash on the third postnatal day. The rash resolved within minutes of PGE1 dose reduction but recurred upon dose escalation, strongly suggesting a causal link. Following surgical palliation and discontinuation of PGE1, the skin findings resolved completely and did not recur. This case underscores a rare but distinctive cutaneous reaction to PGE1 therapy and highlights the importance of early recognition to avoid unnecessary diagnostic testing and interruption of life-saving treatment.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"373-375"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caroline Johanna Agricola, Ilona Efimov, Matthias Augustin, Volker Harth, Albert Nienhaus, Stefanie Mache, Birgit-Christiane Zyriax
{"title":"[Preparedness for professional practice and field preferences of student midwives in Germany].","authors":"Caroline Johanna Agricola, Ilona Efimov, Matthias Augustin, Volker Harth, Albert Nienhaus, Stefanie Mache, Birgit-Christiane Zyriax","doi":"10.1055/a-2625-2758","DOIUrl":"10.1055/a-2625-2758","url":null,"abstract":"<p><p>Student midwives are trained to provide care for women and their families. With academisation in 2019, theoretical education was transferred from vocational schools to institutions of higher education in order to meet the increasing demands of the profession. The aim of this study is to examine the preparedness for professional practice and interprofessional collaboration as well as preferences in fields of practice of student midwives.The cross-sectional study \"Healthy MidStudents\" examining the health and working conditions of student midwives (<i>n</i>=342, response rate 61.3%) was conducted in Northern Germany at nine institutions of higher education between 17 October 2022 and 31 January 2023. The data was analysed using descriptive and inferential statistics.The majority of primary-qualifying students (<i>n</i>=249) rated that they were on average moderately prepared for both the professional practice (47.0%) and interprofessional collaboration (47.4%). Students (<i>n</i>=342) most preferred working in out-of-hospital birth care (24.3%), followed by clinical birth care (21.6%) and out-of-hospital postnatal care (14.6%).The findings implicate measures, e.g. mentoring programmes, to promote preparedness for professional practice and interprofessional collaboration. The study results indicate a broad interest in various fields of practice, particularly in out-of-hospital fields.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"363-372"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12517968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudia Roll, Kerstin Liersch-Baumann, Christoph Bührer
{"title":"[Understaffed nursing shifts and risk-adjusted survival of very preterm infants - an analysis of neonatal intensive care units level 3 in Germany 2019-2023].","authors":"Claudia Roll, Kerstin Liersch-Baumann, Christoph Bührer","doi":"10.1055/a-2618-6341","DOIUrl":"10.1055/a-2618-6341","url":null,"abstract":"<p><p>Higher nurse-to-patient ratios have been linked to decreased mortality and morbidity. Federal German regulations call for nurse shift staffing requirements in neonatal intensive care units and mandatory reporting of understaffed shifts. What is the relationship between the percentage of understaffed nurse shifts and outcome of very preterm infants?We analyzed data published for 163 hospitals providing level 3 neonatal intensive care in Germany 2019-2023, linking percentages of fully staffed nurse shifts with mortality and major morbidity of preterm infants<1500 g birthweight (gestational age 24<sup>0</sup>/<sub>7</sub> bis 31<sup>6</sup>/<sub>7</sub> weeks).No correlation was found between percentages of fully staffed shifts and survival (Rs=0.008, p=0.918) or survival without major morbidity (Rs=0.050, p=0.529). Hospitals with ≤ 95% fully staffed shifts (n=82), as opposed to>95% (n=81), had higher annual caseloads of preterm infants<1500 g (median [interquartile range] 53 [37-77] vs. 41 [33-55], p=0.001) und higher risk-adapted caseloads (56 [35-77] vs. 42 [30-58], p=0.002) while there was no difference in rates of survival relative to the national average (1.00 [0.99-1.01] vs. 1.00 [0.99-1.01], p=0.722) or survival without major morbidity (1.00 [0.97-1.03] vs. 0.99 [0.97-1.02], p=0.346). There were also no significant differences in outcome with other cut-offs or when comparing the lowest with the highest quartile.In this analysis, percentages of understaffed nurse shifts were unrelated to mortality or major morbidity of very preterm infants.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"344-348"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}