Zeitschrift fur Geburtshilfe und Neonatologie最新文献

{"title":"Methylene Blue for Refractory Shock in A Neonate.","authors":"Ferhan Demirtaş, Yasemin Ezgi Köstekci, Aziz Kılıç, Engin Köse, Ömer Erdeve, Tanıl Kendirli, Begum Atasay","doi":"10.1055/a-2625-2706","DOIUrl":"https://doi.org/10.1055/a-2625-2706","url":null,"abstract":"<p><p>Neonatal shock has a high mortality rate in neonates. New treatment approaches are being researched. Methylene blue (MB) may have the ability to enhance blood pressure but is rarely used on newborns. MB usage in a newborn with catecholamine-resistant shock who needed renal replacement therapy (RRT) due to hyperammonemia from an underlying urea cycle defect is presented here. A 3050-g female neonate, born at 38 weeks' gestation, was admitted to our neonatal intensive care unit on the fourth postnatal day due to hyperammonemia and encephalopathy. She was in shock but did not have sepsis, and her cardiological evaluation was normal. Upon detection of severe hyperammonemia, protein intake was ceased and ammonia-reducing medications were initiated. She required RRT due to persistent severe hyperammonemia, but despite receiving fluid resuscitation, vasopressors, and hydrocortisone, her blood pressure remained low until starting MB. Afterwards, RRT waseffectively performed. After continuous RRT, the patient's ammonia level decreased. Unfortunately, the patient died on the tenth day following delivery due to multiple organ failure. Catecholamine-resistant shock is a significant factor in neonatal mortality. In neonates with decompensated catecholamine-resistant shock and normal cardiac function, MB might be a novel therapeutic alternative. However, more studies are required to examine the efficacy, dose, and use.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Predictive Role of Fetal Growth for Placental Invasion Anomalies in Placenta Previa.","authors":"Evrim Koca, Burcu Dincgez, Gulten Ozgen, Deniz Simsek","doi":"10.1055/a-2607-8603","DOIUrl":"https://doi.org/10.1055/a-2607-8603","url":null,"abstract":"<p><p>To evaluate the predictive role of fetal percentile for placental invasion anomalies in placenta previa cases. Study Design: Retrospective studyPlace & Duration of the Study: Training and Research Hospital, January 2018 and December 2023A total of 298 placenta previa cases was divided into two groups: PAS (placenta accreta spectrum)-positive placenta previa (n=98) and PAS-negative placenta previa (n=200). Then PAS-positive placenta previa cases were divided into two subgroups: placenta increta-accreta (n=59) and placenta percreta (n=39). Sociodemographic findings, obstetric features, fetal percentile measurements between 22 and 28 gestational weeks and perioperative characteristics of patients were recorded and compared between groups.Fetal percentile was significantly lower in PAS-positive placenta previa cases as compared to PAS-negative placenta previa cases (p<0.001). Moreover, fetal percentile≤52.5 discriminated PAS-positive placenta previa cases from PAS-negative placenta previa cases with 75.51% sensitivity and 51.5% specificity (p<0.001, AUC=0.654). In multivariate analysis, a fetal percentile of 52.5 and below increased the risk of PAS by approximately 4 times (Hosmer-Lemeshow p=0.101, model p<0.001). No significant difference was detected between placenta percreta and placenta accreta-increta groups in terms of fetal percentile (p=0.224). Fetal percentiles calculated between 22 and 28 gestational weeks could discriminate PAS-positive placenta previa cases from PAS-negative placenta previa cases, although it had no role in discriminating placenta percreta from accreta and increta cases. Therefore, the evaluation of fetal percentile in placenta previa cases can be considered as a supportive finding in the prediction of invasion anomaly although it does not determine the depth of invasion.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annular Migratory Rash In a Newborn Related to Prostaglandin E1 Infusion: A Case Report.","authors":"Buse Önen Ocak, Refika Sirma Dokuzboy, Hayriye Gözde Kanmaz Kutman","doi":"10.1055/a-2615-1248","DOIUrl":"https://doi.org/10.1055/a-2615-1248","url":null,"abstract":"<p><p>Prostaglandin E1 (PGE1, alprostadil) is essential in managing ductus-dependent congenital heart defects (CHD) in neonates. Although its common adverse effects are well documented, dermatologic manifestations remain rare and underrecognized. We report a term male neonate with a prenatal diagnosis of complex critical CHD who required PGE1 infusion and subsequently developed an annular migratory rash on the third postnatal day. The rash resolved within minutes of PGE1 dose reduction but recurred upon dose escalation, strongly suggesting a causal link. Following surgical palliation and discontinuation of PGE1, the skin findings resolved completely and did not recur. This case underscores a rare but distinctive cutaneous reaction to PGE1 therapy and highlights the importance of early recognition to avoid unnecessary diagnostic testing and interruption of life-saving treatment.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Simple Combined Method for Vaginal Breech Presentation Delivery: A Retrospective Single Tertiary Center Comparison of Outcomes Across Two Generational Approaches (2007-2022).","authors":"Christina Kouskouti, Alex Horky, Simon Hajda, Sergej Haide, Franz Kainer","doi":"10.1055/a-2607-7667","DOIUrl":"https://doi.org/10.1055/a-2607-7667","url":null,"abstract":"<p><p>The management of breech presentation at term has been a subject of controversy in recent decades. The Term Breech Trial (TBT) in 2000 demonstrated a significant reduction in perinatal morbidity and mortality through planned cesarean delivery, leading to increased rates of cesarean breech deliveries. Subsequent publications questioned the TBT results, yet without a significant increase in vaginal breech deliveries. This decline in vaginal breech deliveries has raised concerns about the training of the new generation. Here we introduce an individualized approach with careful selection of appropriate candidates and the application of a simple 3-step method (Hold - Lever - Rotate) for vaginal breech delivery.We conducted a retrospective analysis of two distinct periods: 2007-2012 and 2013-2022 to compare approaches to vaginal breech deliveries. The vaginal breech delivery rate was 8% (n=65) from 2007 to 2012 and 10% (n=146) from 2013 to 2022. The success rate for planned vaginal breech deliveries decreased from 62% to 53%.Risk stratification and informed patient selection are pivotal in managing vaginal breech deliveries. The proposed 3-step algorithm (Hold - Lever - Rotate) provides a simple and efficient method for obstetricians and midwives to manage breech deliveries safely, even with limited training opportunities.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effects of Pregnancy on Sexuality, Physical Activity, and Well-Being of Women During Pregnancy].","authors":"Duygu Adiyaman, Andrea Korzoum, Stefan Lukac, Beate Hüner, Christiane Lato, Leonie Burkert, Annika Schmid, Wolfgang Janni, Krisztian Lato","doi":"10.1055/a-2607-7766","DOIUrl":"https://doi.org/10.1055/a-2607-7766","url":null,"abstract":"<p><p>Pregnancy induces significant physical and emotional changes affecting sexual behavior and maternal well-being. This study examined these changes and the possible influence of fetal sex.A total of 320 women with singleton pregnancies in early gestation participated. For analysis, 296 complete questionnaires were included; miscarriages and fetal anomalies were excluded.After pregnancy onset, 27% reported ceasing intercourse; overall frequency declined significantly (p<0.001). Women over 30 showed a stronger decline (p=0.035). Physical activity decreased especially in women under 30 (p=0.038). No significant difference was found between primigravida and multigravida (p=0.173). Common symptoms included low energy (78%), poor sleep (59%), nausea (55%), constipation (49%), increased appetite (46%), and mood swings (45%). Fetal sex had no significant influence on most symptoms (p>0.05). However, concentration problems were more frequent with female fetuses (p=0.024), hair loss with male fetuses (p=0.038). Changes in vaginal discharge occurred more often when fetal sex differed from previous pregnancies (p=0.025).Pregnancy leads to marked changes in sexual behavior, physical activity, and well-being. Understanding these can support more personalized and compassionate prenatal care.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shoulder Dystocia. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/098, 10/2024).","authors":"Peter Jakubowski, Harald Abele, Christian Bamberg, Gerhard Bogner, Katharina Desery, Claudius Fazelnia, Julia Jückstock, Amr Sherif Hamza, Anne Heihoff-Klose, Luise Janning, Andrea Köbke, Ioannis Kyvernitakis, Wolf Lütje, Frank Reister, Anke Reitter, Sven Seeger, Peggy Seehafer, Laila Springer, Axel Valet, Stephanie Wallwiener, Nina Kimmich","doi":"10.1055/a-2588-4890","DOIUrl":"https://doi.org/10.1055/a-2588-4890","url":null,"abstract":"<p><strong>Purpose: </strong>This is an official guideline of the German Society for Gynecology and Obstetrics (<i>Deutsche Gesellschaft für Gynäkologie und Geburtshilfe</i>, DGGG), the Austrian Society for Gynecology and Obstetrics (<i>Österreichische Gesellschaft für Gynäkologie und Geburtshilfe</i>, ÖGGG) and the Swiss Society for Gynecology and Obstetrics (<i>Schweizerische Gesellschaft für Gynäkologie und Geburtshilfe</i>, SGGG). Shoulder dystocia is a rare but feared obstetric complication with potentially far-reaching medical consequences for mother and child. The purpose of this guideline is to standardize the processes which provide individual obstetric solutions for shoulder dystocia in accordance with current scientific knowledge and current clinical practice. The aim is also to emphasize that no matter how good the medical care, shoulder dystocia and its associated complications cannot be entirely prevented and are not fully controllable.</p><p><strong>Methods: </strong>Representative members from different medical specialties were commissioned by the guidelines programm of the DGGG, OEGGG and SGGG to develop this S2k-guideline using a structured consensus process.</p><p><strong>Recommendations: </strong>The guideline provides recommendations about the definition, diagnosis, epidemiology, risk factors and prevention, logistics, and measures to treat shoulder dystocia including an algorithm for action, and the associated complications, documentation requirements, debriefing, forensic aspects, education, training and simulation as well as follow-up discussions on the shoulder dystocia event.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":"229 3","pages":"173-182"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prenatal diagnosis of trisomy 21: Influence of pediatric counseling of pregnant women and contact with families who have an affected child].","authors":"Sandra Kondakov, Florian Faschingbauer, Matthias W Beckmann, Holm Schneider","doi":"10.1055/a-2506-7370","DOIUrl":"10.1055/a-2506-7370","url":null,"abstract":"<p><p>The widespread use of non-invasive prenatal testing (NIPT) has turned prenatal diagnostics for chromosomal abnormalities from the exception to the rule. A common finding is the suspicion of trisomy 21 in the fetus, which should result in the offer of multidisciplinary counseling. The significance of this for decision-making by the pregnant woman has not yet been investigated.Fully anonymized data on pediatric counseling for 251 pregnant women with unclear NIPT findings, suspected or confirmed fetal trisomy 21 were evaluated retrospectively. All consultations on the subject of trisomy 21 in this cohort were conducted by the same experienced pediatrician, who only ended the consultation when the women seeking advice had no more questions and always offered to put them in direct contact with families that include a child affected by trisomy 21. Contact with such families and the outcome of the pregnancy were recorded in each case. Data were analyzed using methods of descriptive statistics and appropriate statistical tests. In particular, the timing of the pediatric consultation, its duration, and contact with families who have an affected child appeared to be relevant to the pregnant women's decision to continue or terminate the pregnancy.If fetal trisomy 21 is suspected, prompt and detailed pediatric counseling and contact with affected individuals are crucial.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"183-187"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Treatment of Aortic Coarctation in an Extremely Low Birth Weight Infant with Balloon Angioplasty.","authors":"Galip Arici, Özkan Kaya, Akif Kavgacı, Hasan Akduman, Utku Arman Örün","doi":"10.1055/a-2479-4873","DOIUrl":"10.1055/a-2479-4873","url":null,"abstract":"<p><p>In our case report, we present a case of successful antegrade balloon angioplasty performed via the femoral vein on a 980-gram neonate with severe coarctation of the aorta. Upon reviewing the literature, we found no cases of balloon angioplasty for coarctation performed via the femoral vein in infants with a lower birth weight than in our case. Our aim is to underline that each patient may require individual evaluation and management options.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"218-220"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of comprehensive nursing combined with ISBAR handover approach in the nursing of patients with placental abruption.","authors":"Qing Yang, Ningning Liu, Wanyang Xie","doi":"10.1055/a-2467-8774","DOIUrl":"10.1055/a-2467-8774","url":null,"abstract":"<p><strong>Objective: </strong>  The research for this paper was conducted to unveil the effect of comprehensive nursing combined with the Identification-Situation-Background-Assessment-Recommendation (ISBAR) handover approach in the nursing of patients with placental abruption.</p><p><strong>Methods: </strong>  The 40 cases of placental abruption patients admitted to the Women's Hospital School of Medicine Zhejiang University from May 2021 to May 2022 were subjected to conventional basic nursing combined with traditional handover tool intervention, which was recorded as the control group; the 40 cases of placental abruption patients admitted to the Women's Hospital School of Medicine Zhejiang University from June 2022 to June 2023 were subjected to comprehensive nursing combined with ISBAR handover tool intervention, which was recorded as the observation group. Maternal and infant outcomes, the quality of nurse handover, and the psychological burden [State Anxiety Inventory (S-AI), Trait Anxiety Inventory (T-AI), Distress Thermometer (DT), and General Self-Efficacy Scale (GSES)] were observed in the two groups, and the satisfaction with nursing was also assessed by using a self-administered satisfaction scale in the two groups.</p><p><strong>Results: </strong>  The rate of normal delivery of patients in the observation group was higher and the rate of cesarean section and the total incidence of complications were lower than that of the control group. The 1- and 5-min Apgar scores of the newborns in the observation group were higher and the total complication rate was lower than that in the control group. Nurses in the observation group had higher scores for nurses' shift handover quality. S-AI, T-AI, and DT scores were lower in both groups after the intervention and were lowest in the observation group; GSES scores were higher and were highest in the observation group. Satisfaction with nursing was higher in the observation group than in the control group.</p><p><strong>Conclusion: </strong>  Comprehensive nursing combined with the ISBAR handover approach applied to the clinical care of patients with placenta abruption can effectively improve the outcomes of mothers and infants, enhance the quality of nurses' shift handovers, reduce the psychological burden of patients and increase nursing satisfaction.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"201-207"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between extraperitoneal and transperitoneal cesarean section: Retrospective case-control study.","authors":"Boris Bačić, Zlatko Hrgović, Anis Cerovac, Ognjen Barčot, Jelena Sabljić, Blagoja Markoski, Mateo Leskur","doi":"10.1055/a-2338-5802","DOIUrl":"10.1055/a-2338-5802","url":null,"abstract":"<p><strong>Introduction: </strong>  The main advantage of extraperitoneal cesarean section (EXPCS) is not only less pain, faster recovery, and less potential for infection but also a possible lack of intraperitoneal adhesions.</p><p><strong>Methods: </strong>  In a 3-year period from 2019 to 2022, 88 EXPCSs were performed. A comparison was made with 90 patients who underwent a standard transperitoneal cesarean section (TPCS). For both groups, the inclusion criterion was uterine inertia and prolonged labor as an indication for cesarean section. Only pregnant women from 37 to 42 weeks were included. After this, 51 patients remained in the EXPCS arm, and 49 remained in the TPCS arm.</p><p><strong>Results: </strong>  No statistical difference was found in gestational weeks, newborn weight, Apgar score, erythrocyte (Er), hemoglobin (Hgb), and hematocrit (Htc) values and duration of operative time between the EXPCS and TPCS groups. Leukocytes, C-reactive protein (CRP) with fever higher than >38°C on the third postoperative day were found statistically significantly (p=0.005) higher in the TPCS group. The usage of tramadol + metamizole at 3, 6, and 9 hours after delivery and diclofenac at 6, 12, and 18 hours after surgery was statistically significantly (p<0.05) higher in the TPCS group. On the visual analog scale (VAS) 24 hours after surgery, a statistically significant difference was found (p = 0.001) between the two groups. In the small group of patients who underwent a TPCS section after an EXPCS, intraperitoneal adhesions were not found; in another group of patients who underwent a TPCS twice, adhesions were found in 12 patients; Fisher's exact test (p=0.04).</p><p><strong>Conclusion: </strong>  The protective effect of EXPCS for infection could be proven in prolonged delivery. EXPCS could be a good solution in the fight against adhesions and infection in women who undergo second, third, or even fourth cesarean sections.</p>","PeriodicalId":23854,"journal":{"name":"Zeitschrift fur Geburtshilfe und Neonatologie","volume":" ","pages":"188-194"},"PeriodicalIF":0.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141627754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}