World Journal of Gastrointestinal Oncology最新文献_第2页

Metastasizing to the colon from triple-negative breast cancer: A case report and review of literature.

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.103328

Ben-Quan Wang, Xing-Gui Fang, Ben-Hong Xiang, Xiao-Jiao Wang, Ming Cao, Cheng-Le Zhuang, Zhong-Chen Liu, Zheng Wang

引用次数: 0

Multiple pseudoprogressions during ongoing immunotherapy-based treatment of advanced gastric neuroendocrine carcinoma: A case report and review of literature.

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.102804

Yan-Hua Mou, Juan Zhang, Hui Shen, Jing Yu, Lan Han, Hui Li, Qing-Feng Li

{"title":"Multiple pseudoprogressions during ongoing immunotherapy-based treatment of advanced gastric neuroendocrine carcinoma: A case report and review of literature.","authors":"Yan-Hua Mou, Juan Zhang, Hui Shen, Jing Yu, Lan Han, Hui Li, Qing-Feng Li","doi":"10.4251/wjgo.v17.i3.102804","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.102804","url":null,"abstract":"Background: Gastric neuroendocrine carcinomas (NECs) exhibit aggressive features, such as rapid growth, higher rate of metastasis, and a generally unfavorable prognosis compared to gastric adenocarcinoma. As a result, therapeutic options for NECs remain limited, contributing to the poor prognosis of patients. Immunotherapy has emerged as a promising treatment strategy and demonstrated the potential to partially improve the survival and prognosis of patients with NECs. Nevertheless, the unique clinical response termed pseudoprogression (PsP) has garnered considerable attention in the context of immunotherapy.Case summary: Presented here is a case of NEC recurrence five and a half months after radical gastric surgery. The 45-year-old male patient underwent combination treatment involving a PD-1 blocker and tyrosine kinase inhibitors and encountered two instances of PsP during treatment. The patient ultimately achieved a durable treatment response without altering his treatment regimens, resulting in a substantial therapeutic benefit.Conclusion: This case report aimed to provide the authors' experience with the diagnosis of PsP and treatment strategies for PsP in ongoing immunotherapy.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"102804"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retrospective analysis of factors influencing the self-healing of patients with enterocutaneous fistulas receiving conservative treatment.

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.101076

Zhuo-Nan Zhuang, Rui Zhao, Yuan-Xin Li

{"title":"Retrospective analysis of factors influencing the self-healing of patients with enterocutaneous fistulas receiving conservative treatment.","authors":"Zhuo-Nan Zhuang, Rui Zhao, Yuan-Xin Li","doi":"10.4251/wjgo.v17.i3.101076","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.101076","url":null,"abstract":"Background: Enterocutaneous (EC) fistula incidence has been increasing in China, along with increases in the volume and complexity of surgeries. The conservative treatment strategy has been analyzed to improve the treatment outcomes for patients with EC fistulas and reduce the need for reoperation.Aim: To analyze the clinical data of patients undergoing conservative treatment for EC fistulas and identify the factors that promote self-healing. These findings provide a reference for improving the clinical cure rate of EC fistulas with conservative treatment.Methods: The clinical data of 91 patients with EC fistulas who underwent conservative treatment were collected. The relationships between the cure rate and characteristics such as age, sex, body mass index, albumin level, primary disease, cause of the fistula, location of the fistula, number of fistulas, nature of the fistula, infection status, diagnostic methods, nutritional support methods, somatostatin therapy, growth hormone therapy, and fibrin glue therapy were analyzed.Results: A comparison of the basic patient characteristics between the two groups revealed statistically significant differences in primary disease (P = 0.044), location of the fistula (P = 0.006), number of fistulas (P = 0.007), and use of adhesive sealing (χ 2 = 12.194, P < 0.001) between the uncured and cured groups. The use of fibrin glue was a significant factor associated with a cure for fistulas (odds ratio = 5.459, 95%CI: 1.958-15.219, P = 0.01).Conclusion: The cure rate of patients with a single EC fistula can be effectively improved via conservative treatment combined with the use of biological fibrin glue to seal the fistula.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"101076"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current research status and future directions of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma.

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.99068

Meer M Chisthi

{"title":"Current research status and future directions of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma.","authors":"Meer M Chisthi","doi":"10.4251/wjgo.v17.i3.99068","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.99068","url":null,"abstract":"The rapid evolution of systemic therapies for hepatocellular carcinoma (HCC), one of the most common types of liver cancer, has attracted significant attention especially to hepatic arterial infusion chemotherapy (HAIC) as a highly promising treatment approach. This method, which delivers chemotherapy directly into the liver's arterial supply, is designed to maximize the concentration of anti-cancer drugs at the tumor site while minimizing systemic side effects. Despite the potential and the encouraging results observed in various studies, HAIC has not yet achieved widespread acceptance and utilization. Sorafenib is a widely used systemic therapy that targets multiple pathways involved in tumor growth and angiogenesis, while transarterial chemoembolization (TACE) is a locoregional therapy that combines arterial embolization with chemotherapy. These treatments have been the mainstay of HCC management, yet they have limitations that HAIC may potentially overcome. This article specifically comments on the network meta-analysis that examined the current research status of HAIC, highlighting its effectiveness and safety profile in comparison to established standard treatments such as Sorafenib and TACE. Through an extensive review of existing studies, the authors conclude that patients receiving HAIC often experience better survival rates and longer periods without disease progression compared to those receiving Sorafenib or TACE.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"99068"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stoma related complications: A registry study based on a prospective registration system.

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.102604

Nan Chen, Jie Zhang, Lin Wang, Qian Yang, Ai-Wen Wu

{"title":"Stoma related complications: A registry study based on a prospective registration system.","authors":"Nan Chen, Jie Zhang, Lin Wang, Qian Yang, Ai-Wen Wu","doi":"10.4251/wjgo.v17.i3.102604","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.102604","url":null,"abstract":"Background: Stoma creation is a common procedure in colorectal cancer surgery, however, stoma-related complications remain a significant concern.Aim: To investigate the incidence, types, and risk factors of stoma-related complications in colorectal cancer patients who underwent stoma creation.Methods: Patients with stoma was prospectively recorded in the established stoma system. Data was collected from this stoma management system from November 2021 through May 2024. The rates of stoma-related complications were assessed, and potential risk factors were analyzed using univariate and multivariate logistic regression models.Results: A total of 734 patients were included in the analysis. The results showed that 12.3% of patients experienced stoma-related complications, with mucocutaneous separation, edema, and skin excoriation being the most common complications. The majority (90%) of complications were classified as grade 2 according to the Clavien-Dindo classification. Surgical factors, such as blood loss volume greater than 500 mL and open surgery, were significantly associated with stoma complications. Additionally, stoma features like location, shape, color, height, and edema were important factors in the association with complications. Body mass index over 30 kg/m² was also found to be a significant risk factor.Conclusion: These findings highlight the need for a holistic approach to preventing and managing stoma complications, considering both patient-related and surgical factors.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"102604"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heterochronic gastric adenosquamous carcinoma combined with colonic adenoma: A case report.

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.101734

Gui-Jiang Liu, Xiao-Yi Long, Fei Zhang, Tao Ren, Xun Xia

{"title":"Heterochronic gastric adenosquamous carcinoma combined with colonic adenoma: A case report.","authors":"Gui-Jiang Liu, Xiao-Yi Long, Fei Zhang, Tao Ren, Xun Xia","doi":"10.4251/wjgo.v17.i3.101734","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.101734","url":null,"abstract":"Background: Metachronous gastric cancer usually refers to a tumor that occurs in the stomach more than half a year after esophageal cancer surgery, and metastasis of primary esophageal cancer should be excluded. There are few reports of metachronous gastric adenosquamous carcinoma with signet ring cell carcinoma combined with early tubular adenoma of the colon after esophageal cancer surgery, which has a high degree of malignancy. This is also the reason for the poor treatment results.Case summary: A 54-year-old male patient was admitted to the hospital with \"dysphagia obstruction\". Seven years ago, the patient was diagnosed with well-differentiated squamous cell carcinoma in the middle esophagus (T4N1M0 stage) and left gastric lymph node metastasis. In the final resection of the esophageal cancer, no residual cancer tissue was found in the esophageal and gastric stump. The patient's medical history 7 years ago (preoperative gastroscopy and other examinations) revealed no gastric tumor. Combined with the patient's history, the diagnosis of recurrent esophageal cancer was made on this admission. The final pathological results were surprising: Metachronous gastric adenosquamous carcinoma with signet ring cell carcinoma combined with early tubular adenoma of the colon. Considering the high malignancy of the tumor, the complexity of the second operation, and many complications, the patient received chemotherapy.Conclusion: He had a history of esophageal cancer resection. Gastroenteroscopy should be performed simultaneously to avoid missed diagnosis and misdiagnosis.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"101734"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increased risk of colorectal cancer in young males with higher cardiovascular risk: A nationwide population-based cohort study.

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.101260

Ji Hyun Song, Su-Yeon Choi, Young Sun Kim, Sun Young Yang, Kyung-Do Han

{"title":"Increased risk of colorectal cancer in young males with higher cardiovascular risk: A nationwide population-based cohort study.","authors":"Ji Hyun Song, Su-Yeon Choi, Young Sun Kim, Sun Young Yang, Kyung-Do Han","doi":"10.4251/wjgo.v17.i3.101260","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.101260","url":null,"abstract":"Background: Although the link between cardiovascular disease (CVD) and various cancers is well-established, the relationship between CVD risk and colorectal cancer (CRC) remains underexplored.Aim: To elucidate the relationship between CVD risk scores and CRC incidence.Methods: In this population-based cohort study, participants from the 2009 National Health Checkup were followed-up until 2020. The cardiovascular (CV) risk score was calculated as the sum of risk factors (age, family history of coronary artery disease, hypertension, smoking status, and high-density lipoprotein levels) with high-density lipoprotein (≥ 60 mg/dL) reducing the risk score by one. The primary outcome was incidence of newly diagnosed CRC.Results: Among 2526628 individuals, 30329 developed CRC during a mean follow-up of 10.1 years. Categorized by CV risk scores (0, 1, 2, and ≥ 3). CRC risk increased with higher CV risk scores after adjusting for covariates [(hazard ratio = 1.155, 95% confidence interval: 1.107-1.205) in risk score ≥ 3, P < 0.001]. This association was exclusively observed in males, most notably in the younger cohort (< 50 years) and was more pronounced in individuals not using statins. Moreover, even in participants without diabetes, a higher CV risk was associated with an increased CRC risk.Conclusion: Increased CV risk scores were significantly associated with higher CRC risk, especially among males, younger populations, and non-statin users. Thus, males with a higher CV risk score, even at a younger age, are recommended to control their risk factors and undergo individualized CRC screening.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"101260"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastric cancer diagnosis and prevention: Detecting precancerous at community level. 胃癌诊断与预防：在社区一级检测癌前病变。

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.100521

Sergey M Kotelevets, Sergey Z Chukov

{"title":"Gastric cancer diagnosis and prevention: Detecting precancerous at community level.","authors":"Sergey M Kotelevets, Sergey Z Chukov","doi":"10.4251/wjgo.v17.i3.100521","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.100521","url":null,"abstract":"The problem of gastric cancer (GC) prevention remains relevant for a long time. Various methods of population serological screening of atrophic gastritis and precancerous changes in the gastric mucosa have been created at present. Modern endoscopic and morphological methods of verification of the diagnosis of precancerous diseases and changes in the gastric mucosa have been introduced into the practice of gastroenterologists and oncologists. GC risk stratification systems allow the formation of risk groups that require population screening. Practical hints for population serological screening of atrophic gastritis, endoscopic and morphological verification of precancerous changes and diseases of the stomach recommend using it: When developing state programs for the prevention of stomach cancer; when implementing preventive measures for stomach cancer by doctors of all specialties; the authors also offer the possibility of use by anyone over the age of 40, provided that they seek methodological help from their doctor; in the work of health schools in any medical and preventive institutions. The use of an assessment system of certain risk factor signatures with prognostic value would add significant assistance to preventive measures against GC.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"100521"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current impact in the treatment of advanced hepatocellular carcinoma: The challenge remains. 晚期肝细胞癌治疗的当前影响：挑战依然存在。

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.102932

Angelo A de Mattos, Cristiane V Tovo, Isadora Z Bombassaro, Luis F Ferreira

{"title":"Current impact in the treatment of advanced hepatocellular carcinoma: The challenge remains.","authors":"Angelo A de Mattos, Cristiane V Tovo, Isadora Z Bombassaro, Luis F Ferreira","doi":"10.4251/wjgo.v17.i3.102932","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.102932","url":null,"abstract":"Hepatocellular carcinoma remains a significant cause of mortality worldwide, particularly among patients with liver cirrhosis. In most cases, surveillance in cirrhotic patients is neglected, leading to a diagnosis when the neoplasm is at an advanced stage. Within this context, Zhou et al carried out a network meta-analysis to demonstrate the effectiveness of hepatic arterial infusion chemotherapy, concluding that it is a superior approach compared to sorafenib and transarterial chemoembolization in the treatment of advanced hepatocellular carcinoma. Unfortunately, the meta-analysis in question lacks methodological rigor, preventing the authors from making more definitive assertions. Additionally, we understand that transarterial chemoembolization, when properly indicated, is a highly effective therapeutic option, and that sorafenib, given the results of new therapies based on immune checkpoint inhibitors, is no longer the recommended drug for the treatment of these patients. Therefore, we believe the use of hepatic arterial infusion chemotherapy is increasingly limited and lacks strong scientific support.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"102932"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transmembrane protein 176B promotes epithelial-mesenchymal transition in colorectal cancer through inflammasome inhibition.

IF 2.5 4区医学

World Journal of Gastrointestinal Oncology Pub Date : 2025-03-15 DOI: 10.4251/wjgo.v17.i3.97673

Wei Qian, Chong-Yi Xu, Wei Hong, Zhe-Ming Li, Dao-Gun Xu

{"title":"Transmembrane protein 176B promotes epithelial-mesenchymal transition in colorectal cancer through inflammasome inhibition.","authors":"Wei Qian, Chong-Yi Xu, Wei Hong, Zhe-Ming Li, Dao-Gun Xu","doi":"10.4251/wjgo.v17.i3.97673","DOIUrl":"https://doi.org/10.4251/wjgo.v17.i3.97673","url":null,"abstract":"Background: Activation of the epithelial-mesenchymal transition (EMT), a pivotal process in tumor metastasis and evasion, as well as the NLRP3 inflammasome, both promote colorectal cancer (CRC) progression. Recent studies have shown that Transmembrane protein 176B (TMEM176B) regulates NLRP3 and promotes CRC malignant phenotypes.Aim: To investigate the role of TMEM176B in modulating NLRP3 inflammasome and its implications on EMT and tumor progression in CRC.Methods: CRC in situ mouse and co-cultured cell models were established using CT26 cells, BALB/c mice, and primary cultured mouse natural killer (NK) cells. Short hairpin RNA knocked down TMEM176B and NLRP3 expression in CT26 cells. Fluorescence imaging, Terminal deoxynucleotidyl transferase dUTP nick end labeling assays, immunohistochemistry staining, flow cytometry, and molecular assays were used to investigate the effects of TMEM176B knockdown on the NLRP3 inflammasome in NK cells to assess tumor metastasis, apoptosis, and EMT indicators.Results: Silencing TMEM176B in CRC mice significantly reduced tumor metastasis, proliferation, and EMT, while activating apoptosis, NLRP3 inflammasome, and NK cell activity. Furthermore, silencing TMEM176B in co-cultured cell models inhibited cell migration and invasion, and promoted apoptosis. The interference of NLRP3 reversed these effects by modulating key proteins such as phosphorylated nuclear factor kappa B subunit 1 p65, matrix metallopeptidase 9, and transforming growth factor-β.Conclusion: This study highlights the critical role of TMEM176B/NLRP3 in CRC progression and provides a basis for targeting this axis as a novel therapeutic approach to manage CRC progression and metastasis.","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"97673"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0