Ben-Quan Wang, Xing-Gui Fang, Ben-Hong Xiang, Xiao-Jiao Wang, Ming Cao, Cheng-Le Zhuang, Zhong-Chen Liu, Zheng Wang
{"title":"Metastasizing to the colon from triple-negative breast cancer: A case report and review of literature.","authors":"Ben-Quan Wang, Xing-Gui Fang, Ben-Hong Xiang, Xiao-Jiao Wang, Ming Cao, Cheng-Le Zhuang, Zhong-Chen Liu, Zheng Wang","doi":"10.4251/wjgo.v17.i3.103328","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Breast cancer (BC) metastasis to the gastrointestinal tract is uncommon, colonic metastasis from BC (CMBC) is even rarer.</p><p><strong>Case summary: </strong>This report describes a 44-year-old female patient with metastatic triple-negative BC in the ascending colon who underwent laparoscopic radical right hemicolectomy. The patient had undergone left modified radical mastectomy only 15 months ago and stopped chemotherapy just 3 months ago. The diagnosis of CMBC was made based on the previous history of BC and positive results of several specific immunohistochemical markers (gross cystic disease fluid protein 15, mammaglobin, GATA-binding protein 3, and cytokeratin 7) for breast carcinoma.</p><p><strong>Conclusion: </strong>CMBC should be highly cautious in patients with a previous history of BC, especially triple-negative BC, and further examination to aid in diagnosis.</p>","PeriodicalId":23762,"journal":{"name":"World Journal of Gastrointestinal Oncology","volume":"17 3","pages":"103328"},"PeriodicalIF":2.5000,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866245/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Gastrointestinal Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4251/wjgo.v17.i3.103328","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Breast cancer (BC) metastasis to the gastrointestinal tract is uncommon, colonic metastasis from BC (CMBC) is even rarer.
Case summary: This report describes a 44-year-old female patient with metastatic triple-negative BC in the ascending colon who underwent laparoscopic radical right hemicolectomy. The patient had undergone left modified radical mastectomy only 15 months ago and stopped chemotherapy just 3 months ago. The diagnosis of CMBC was made based on the previous history of BC and positive results of several specific immunohistochemical markers (gross cystic disease fluid protein 15, mammaglobin, GATA-binding protein 3, and cytokeratin 7) for breast carcinoma.
Conclusion: CMBC should be highly cautious in patients with a previous history of BC, especially triple-negative BC, and further examination to aid in diagnosis.
期刊介绍:
The World Journal of Gastrointestinal Oncology (WJGO) is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of gastrointestinal oncology.