Claudia P Ceballos, Estefanía Aristizábal-Parra, Viviana E Castillo-Vanegas
{"title":"Hematology and serum biochemistry reference intervals for the common opossum Didelphis marsupialis.","authors":"Claudia P Ceballos, Estefanía Aristizábal-Parra, Viviana E Castillo-Vanegas","doi":"10.1007/s11259-025-10684-1","DOIUrl":"10.1007/s11259-025-10684-1","url":null,"abstract":"<p><p>The common opossum, Didelphis marsupialis, is a neotropical and synanthropic marsupial common and widespread in Latin America. The strong human-opossum conflict that results in high numbers of individuals with health problems demands information on physiological parameters to be used in veterinary medicine practice. The aim of this study was to estimate the reference intervals (RI) of hematology and serum biochemistry for this species which are lacking and evaluate its variability. Out of the 61 apparently healthy wild opossums evaluated, we found significant variability in the RI´s associated sex, life stage, habitat, and the reproductive stage of females. Males had higher values of RBC and hemoglobin than females, but females had higher values of MCH than males. Juveniles had higher values of MCV and MCH, but adults had higher values RBC, WBC and neutrophils. In addition, rural opossums had higher values of hemoglobin, MCHC, MCH and platelets, but urban opossums had higher values of WBC, particularly neutrophils and lymphocytes. Opossums are exposed to many different stressors in urban settings, and further research is needed to understand these physiological responses to urbanization. Finally, lactating females had higher values of monocytes and basophils compared to non-lactating females, potentially providing passive immunity through the milk to the immature neonates in the marsupium.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"123"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Micheli Zaminhan-Hassemer, Gustavo Botton Zagolin, Bruno Cavalheiro Aráujo, Caio Augusto Perazza, David Aciole Barbosa, Fabiano B Menegidio, Luiz Lehmann Coutinho, Polyana Tizioto, Alexandre Wagner Silva Hilsdorf
{"title":"Effect of green propolis crude extract on the modulation of intestinal microbiota and on the productive performance of juvenile Nile tilapia.","authors":"Micheli Zaminhan-Hassemer, Gustavo Botton Zagolin, Bruno Cavalheiro Aráujo, Caio Augusto Perazza, David Aciole Barbosa, Fabiano B Menegidio, Luiz Lehmann Coutinho, Polyana Tizioto, Alexandre Wagner Silva Hilsdorf","doi":"10.1007/s11259-025-10683-2","DOIUrl":"10.1007/s11259-025-10683-2","url":null,"abstract":"<p><p>The study aimed to investigate the impact of dietary supplementation with green propolis crude extract on juvenile tilapia's growth and intestinal microbiota. The experiment was conducted in raceway tanks with a volume of 19m<sup>3</sup>, comprising two treatments with three replicates each. Fish were assigned to either a control diet or a diet supplemented with 0.67% green propolis crude extract. Each experimental unit consisted of 30 fish, initially averaging 22.38 g ± 0.32 in weight, and which were fed ad libitum for 60 days. Results demonstrated that dietary supplementation with green propolis crude extract significantly improved the growth of juvenile tilapia compared to the control group. Firmicutes, Proteobacteria, Verrucomicrobia, Bacteroidetes, and Cyanobacteria were identified as the predominant bacterial phyla in the intestinal microbiota of both groups. The genera Candidatus xiphinematobacter (Verrucomicrobia) and Somerae (Firmicutes) were consistently abundant across treatments, with Somerae and Dispar as the most prevalent species. Significant differences in alpha diversity were observed between treatments at the genus and species levels according to the Chao 1 index. However, no significant differences were detected in Shannon index diversity between the control and green propolis crude extract groups. Beta diversity analysis revealed distinct clustering between treatments. Linear discriminant analysis Effect Size (LEfSe) highlighted significant differences in bacterial abundance between the control and green propolis crude extract groups. In conclusion, dietary supplementation with green propolis crude extract improved growth. It also modulated the intestinal microbiota of juvenile Thai tilapia.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"120"},"PeriodicalIF":1.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tunçer Türkoğlu, Ünal Parlak, Pelin Tuncer-Göktuna, Eylem Aras-Uzun, Sena İnel-Turgut, Erdoğan Asar, Ayça Kürkçü, Can Çokçalışkan
{"title":"Duration of the antibody response following intradermal administration of a quarter-dose oil adjuvant foot-and-mouth disease vaccine in sheep.","authors":"Tunçer Türkoğlu, Ünal Parlak, Pelin Tuncer-Göktuna, Eylem Aras-Uzun, Sena İnel-Turgut, Erdoğan Asar, Ayça Kürkçü, Can Çokçalışkan","doi":"10.1007/s11259-025-10686-z","DOIUrl":"10.1007/s11259-025-10686-z","url":null,"abstract":"<p><p>Foot-and-mouth disease is a significant viral disease affecting cloven-hoofed domestic and wild animals. One of the most effective measures for combating this disease is vaccination. However, sheep are often excluded from vaccination campaigns because of vaccine shortages. Intradermal vaccination can significantly reduce the quantity of antigens and adjuvants required, thereby increasing vaccine availability. Although numerous experimental studies have been conducted on the intradermal administration of the FMD vaccine, no such studies have been conducted on sheep, and the duration of antibody response for this species remains unclear. Inactivated antigens for foot-and-mouth disease, including O/Panasia-II, A/IRN-05, A/ASIA/G-VII, and ASIA1/Sindh-08, were formulated using ictyolane 18 and ictyolane 30 adjuvants to prepare water-in-oil-in-water and microemulsions. Forty-five Merino sheep were randomly divided into four groups of 10 animals each, with one unvaccinated group containing five animals. One mL of vaccine (> 3PD<sub>50</sub>) was administered intramuscularly to the intramuscular groups (IM18 and IM30), whereas 1/4 mL was administered intradermally to intradermal groups (ID18 and ID30). A booster dose was administered to all groups on day 28. Blood samples were collected from the sheep at various intervals: days 0, 7, 14, 28, 58, 86, 118, 151, 179, 211, 241, 270, 302, 338, and 361. Serum antibody levels were determined using VNT and LPB-ELISA. No difference was observed between the reduced-dose intradermal and full-dose intramuscular administration of Ictyolane 18 (ICT18) vaccine formulation (p > 0.05) in terms of antibody level and duration in sheep. It has been observed that the Ictyolane 18 formulations generally stimulate a higher antibody response than the Ictyolane 30 formulations.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"119"},"PeriodicalIF":1.8,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intracoronary cytoprotective gene therapy in a dog with dilated cardiomyopathy: long term follow up.","authors":"Paola Paradies, Lucia Carlucci, Serena Digiaro, Alessandra Recchia, Antonella Colella, Felix Woitek, Luca Lacitignola, Francesco Staffieri, Mauro Giacca, Fabio Anastasio Recchia","doi":"10.1007/s11259-025-10691-2","DOIUrl":"10.1007/s11259-025-10691-2","url":null,"abstract":"<p><p>In large breed dogs, dilated cardiomyopathy (DCM) is the main cause of congestive heart failure (CHF) and sudden cardiac death. The underlying etiology of DCM is usually not definitively identified; however, in predisposed breeds a hereditary etiology is often suspected. Other etiologies, such as toxins and infections, have also been documented or suspected to cause DCM in dogs. Conventional drug treatment cannot reverse disease progression but can only control the signs of heart failure as they occur. Cytoprotective gene therapy with Vascular Endothelial Growth Factor-B167 (VEGF-B167) has been shown to be an effective alternative therapy that can halt disease progression in preclinical experimental studies in dogs. This study reports the long-term clinical and echocardiographic follow-up of a 6-year-old St. Bernard dog with DCM treated with intracoronary administration of VEGF-B167 gene delivered by adeno-associated viral vectors (AAV- VEGF-B167). Monitoring was performed at 1, 3, 6, 9, 12, 18, 24 and 36 months post-procedure (T0-T8) including clinical, laboratory and instrumental examinations. The dog reached T8 in good clinical condition. Comparing echocardiographic parameters from T0 to T8, ejection fraction (EF%) did not worsen, indeed showing potential improvement (30% to 38% from T0 to T8 respectively) (Simpson method). Other parameters of disease progression varied minimally over the course of the study. From T0 to T8, no relevant change in medical therapy was necessary. The dog survived 341 days from the last follow-up and died of sudden death 1436 days after the procedure (T0). A survival time of 4 years in good health is an excellent outcome suggesting a possible protective role of VEFG-B167 in slowing disease progression in this dog.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"117"},"PeriodicalIF":1.8,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11861415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucas Vinícius de Oliveira Ferreira, Leandro Maia, Danilo Giorgi Abranches de Andrade, Beatriz da Costa Kamura, Márcio de Carvalho, Rogério Martins Amorim
{"title":"Therapeutic potential of mesenchymal stem cells transplantation on traumatic facial nerve paralysis in two horses.","authors":"Lucas Vinícius de Oliveira Ferreira, Leandro Maia, Danilo Giorgi Abranches de Andrade, Beatriz da Costa Kamura, Márcio de Carvalho, Rogério Martins Amorim","doi":"10.1007/s11259-025-10692-1","DOIUrl":"10.1007/s11259-025-10692-1","url":null,"abstract":"<p><p>Cell-based therapy has emerged as a promising strategy for treating peripheral nervous system (PNS) injuries across different species. However, there is a scarcity in the literature regarding the transplantation of mesenchymal stem cells (MSCs) for treating PNS injuries in horses. This report aims to describe the therapeutic potential of equine MSC transplantation in two horses with chronic traumatic facial nerve paralysis. Both horses presented with lip ptosis and right deviation of the nostril and upper lip, being clinically diagnosed with left facial nerve paralysis. Due to the refractoriness to conventional anti-inflammatory treatments, cell-based therapy was chosen. One horse received an autologous transplant of equine bone marrow-derived MSCs (EqBM-MSCs) four months after the traumatic event, while the other underwent three transplants of allogeneic equine adipose tissue-derived MSCs (EqAT-MSCs) at 30-day intervals, starting two months after the injury. All transplants were performed at three different sites around the facial nerve, at the level of bifurcation of the buccal branch in both horses. Physical and neurological assessments revealed significant clinical recovery within three months for the first horse and four months for the second. These findings demonstrated that equine MSCs transplants have great therapeutic potential for chronic traumatic facial nerve paralysis in horses, highlighting the relevance of MSCs- based therapy for peripheral nerve injuries.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"118"},"PeriodicalIF":1.8,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin-Wen Su, Xin-Wen Hou, Shuo Liu, Yu Chen, Ji-Xin Zhao, Xiao-Xuan Zhang, Hong-Bo Ni, He Ma, Rui Liu
{"title":"Dynamic characterization of the changes in intestinal fungi and fecal metabolites during the reproductive cycle of sows.","authors":"Jin-Wen Su, Xin-Wen Hou, Shuo Liu, Yu Chen, Ji-Xin Zhao, Xiao-Xuan Zhang, Hong-Bo Ni, He Ma, Rui Liu","doi":"10.1007/s11259-025-10665-4","DOIUrl":"10.1007/s11259-025-10665-4","url":null,"abstract":"<p><p>Pregnancy-induced changes in the intestinal microbiota have been widely demonstrated. However, the research on the alterations of intestinal fungi and fecal metabolism during the reproductive cycle of sows is limited. In this study, fresh fecal samples were collected from 12 sows during the second day before fertilization (SBF), early pregnancy period (EEP; including gestational days 28, 42, and 56), late pregnancy period (LPP; including gestational days 70, 84, and 98), farrowing day (FD; collected after delivery), and lactation period (LAC, including days 7, 14, and 21 postpartum) for Internal Transcribed Space amplicon sequencing and untargeted metabolomics sequencing. The results indicated that intestinal fungi and fecal metabolites underwent significant dynamic changes during EPP and LPP, stabilizing after FD. Correlation analysis revealed a significant association between intestinal fungi and fecal metabolites, suggesting a potential role of intestinal fungi in the regulation of host health and reproductive performance. These results indicated that pregnancy may play a key role in driving the dynamic changes in intestinal fungi and fecal metabolites observed throughout the reproductive cycle. This study explores the dynamic changes and correlations of intestinal fungi and fecal metabolites in sows, providing theoretical insights for sow breeding production, feed management, and the development of microecological agents.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"116"},"PeriodicalIF":1.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Imogen L Payne, Keith Rogers, Alan Tevendale, Andrew F Rich
{"title":"Cholelithiasis in two zoo-managed male African lions (Panthera leo).","authors":"Imogen L Payne, Keith Rogers, Alan Tevendale, Andrew F Rich","doi":"10.1007/s11259-025-10689-w","DOIUrl":"10.1007/s11259-025-10689-w","url":null,"abstract":"<p><p>Cholelithiasis is a rarely reported condition in lions and zoological carnivora. This report documents two geriatric, male, African lions (Panthera leo; Lions A and B) submitted for routine necropsy following euthanasia due to unrelated conditions. Pre-euthanasia serum biochemistry revealed unremarkable hepatobiliary markers for both lions. On necropsy, cholelithiasis was observed in both individuals, with Lion A displaying more severe gallstone accumulation and a biliary cystadenoma. Gallstones from Lion A were analysed using X-ray diffraction, element content analysis, and scanning electron microscopy. Findings revealed that the black appearance of the choleliths, the absence of acicular cholesterol, and minimal calcium content (1.05%) were consistent with bilirubin polymer composition. Risk factors for cholelithiasis in these lions may have included geriatric age, sex (male), good body condition, and chronic biliary tract inflammation. This case report presents the first documented instances of incidental cholelithiasis in African lions, providing novel findings into its composition (bilirubin polymers), possible risk factors, and histopathological features.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"114"},"PeriodicalIF":1.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contagious ecthyma in small ruminants: from etiology to vaccine challenges - a review.","authors":"Caroline Reichen, Breno Castello Branco Beirão, Alda Lúcia Gomes Monteiro","doi":"10.1007/s11259-025-10677-0","DOIUrl":"10.1007/s11259-025-10677-0","url":null,"abstract":"<p><p>Orf virus (ORFV) is an epitheliotropic, double-stranded DNA pathogen belonging to the genus Parapoxvirus, and it is the causative agent of contagious ecthyma (CE) in small ruminants. It is an endemic disease on goat and sheep herds around the world. It is often a neglected disease, with impacts on herd health and productivity, while also being an occupational zoonosis. This review explores the causative agent of ovine ecthyma, its epidemiology, and clinical manifestations, with a particular emphasis on its interaction with the host's immune system and the development of ORFV vaccines. Like other members of the Poxviridae family, ORFV expresses numerous immunomodulatory genes, which complicate vaccination efforts and disease management. This review highlights the challenges posed by ORFV in achieving effective immunization and discusses potential vaccine strategies to overcome these obstacles.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"115"},"PeriodicalIF":1.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giulia Maggi, Elena Rosi, Simone Cupido, Salvatore Palma, Maria Chiara Marchesi
{"title":"Bronchial foreign body caused by a grasshopper in a dog.","authors":"Giulia Maggi, Elena Rosi, Simone Cupido, Salvatore Palma, Maria Chiara Marchesi","doi":"10.1007/s11259-025-10687-y","DOIUrl":"10.1007/s11259-025-10687-y","url":null,"abstract":"<p><p>An 11-year-old dog living in a rural area of Italy was evaluated for a persistent cough. Diagnostic imaging findings, combined with the clinical history and physical examination, revealed focal pneumonia, raising suspicion of a vegetal foreign body. Bronchoscopy identified a foreign body (a grasshopper) partially obstructing the left caudal bronchus, and its removal was successfully performed. Insects should be considered potential bronchial foreign bodies in the differential diagnosis.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"113"},"PeriodicalIF":1.8,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Barakat M Alrashdi, Mousa O Germoush, Ibrahim B Abdel-Farid, Diaa Massoud, Eman Kamal Khalil, Ahmed G Nomir, Mohamed Abumandour
{"title":"Sublingual and subpharyngeal floor, beak, and palate of the local Egyptian ISA Brown Hen (Gallus gallus Domesticus): gross, morphometric, and scanning electron microscopic features with new insights into their nutritional adaptations.","authors":"Barakat M Alrashdi, Mousa O Germoush, Ibrahim B Abdel-Farid, Diaa Massoud, Eman Kamal Khalil, Ahmed G Nomir, Mohamed Abumandour","doi":"10.1007/s11259-025-10682-3","DOIUrl":"10.1007/s11259-025-10682-3","url":null,"abstract":"<p><p>This study is the first attempt to describe the morphological features of the sublingual and subpharyngeal floor, beak, and palate of the Egyptian ISA Brown Hen using gross and SEM examinations. The rostral part of the lower beak, not occupied by the tongue, was organized into three areas: rostral papillary-teeth-like, non-ridged, and ridged. The sublingual part has a median ridge and two sublingual gland openings; the large round openings are along the ridge, while the small ovoid openings are along each half. The sublaryngeal region contained three sublaryngeal ridges. The oropharyngeal roof papillary system is classified into palatine and pharyngeal (one dorsal transverse row and the two ventral transverse rows) systems. The palatine papillary system has five transverse papillary rows on the choanal field and two longitudinal papillary rows (one on each side of the choanal opening). The choana is divided into a long, narrow rostral part and a wide, short caudal part. The choana is surrounded by an elevated papillary fold of 7-10 small papillae, arranged in a pattern of 2-3 papillae between the transverse ridges. The caudal part is bordered by two longitudinal papillary rows without an elevated border, with 6-8 papillae. A papillary border encircled the choana. There are fifteen ridges on the roof: eight longitudinal and seven transverse ridges. Each lateral longitudinal palatine region carried 6-8 tooth-like rostrally directed projections. Our findings suggested that the oropharyngeal cavity plays a key role in determining how the bird's nutritional mechanism adapts to the Egyptian environment.</p>","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"49 2","pages":"112"},"PeriodicalIF":1.8,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}