Veterinary Research Communications最新文献_第3页

Systemic use of terbinafine in veterinary medicine: A review of pharmacokinetic studies. 特比萘芬在兽药中的全身应用：药代动力学研究综述。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-29 DOI: 10.1007/s11259-026-11232-1

Lainey Harvill, Sherry Cox

{"title":"Systemic use of terbinafine in veterinary medicine: A review of pharmacokinetic studies.","authors":"Lainey Harvill, Sherry Cox","doi":"10.1007/s11259-026-11232-1","DOIUrl":"https://doi.org/10.1007/s11259-026-11232-1","url":null,"abstract":"Terbinafine is an orally and topically active allylamine antifungal agent with fungistatic and fungicidal action. Its mechanism of action is the competitive inhibition of squalene epoxidase which leads to squalene accumulation and ergosterol depletion in the cell membrane. Clinically relevant pathogens can include but are not limited to: Aspergillus spp., Candida spp., Blastomyces dermatitidis, Histoplasma capsulatum, Emydomyces testavorans, Ophidiomyces ophiodiicola, and Batrachochytrium dendrobatidis. Terbinafine is an antifungal drug that has been used successfully in humans with few adverse effects. It is not licensed in the United States for systemic use in veterinary medicine but is routinely used in an extra label manner to treat fungal infections. Terbinafine has been well tolerated in domesticated and non-domesticated animals that have been studied. The studies that are available suggest that species differences exist in pharmacokinetics and further research is necessary to establish recommended doses in individual species. Due to the variation, terbinafine should be investigated on a species-by-species basis to determine its effective and safe use, thus ensuring the wellbeing of animals.","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"50 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ursolic acid methyl ester mitigates aluminum oxide nanoparticle-induced hematobiochemical, immune, and oxidative disturbances and modulates apoptosis-related gene expression in Oreochromis niloticus. 熊果酸甲酯减轻氧化铝纳米颗粒诱导的血液生化、免疫和氧化干扰，并调节尼罗河Oreochromis凋亡相关基因表达。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-29 DOI: 10.1007/s11259-026-11219-y

Abdallah Tageldein Mansour, Walaa El-Houseiny, Ahmed S AlSaqufi, Yousef Alkhamis, Adham A Al-Sagheer, Engy M M Mohamed

引用次数: 0

Intramedullary pin fixation for a transverse diaphyseal fracture of the femur in a sugar glider (Petaurus breviceps). 髓内钉固定治疗糖滑翔机（短胸肌）股骨横突骨折。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-29 DOI: 10.1007/s11259-026-11240-1

Fabian Dewangga Putra Warsito, Ribka Vania Rusli

{"title":"Intramedullary pin fixation for a transverse diaphyseal fracture of the femur in a sugar glider (Petaurus breviceps).","authors":"Fabian Dewangga Putra Warsito, Ribka Vania Rusli","doi":"10.1007/s11259-026-11240-1","DOIUrl":"https://doi.org/10.1007/s11259-026-11240-1","url":null,"abstract":"Sugar gliders (Petaurus breviceps) are increasingly popular as pets yet there is little published guidance on orthopaedic management of long bone fractures in this species. We report a case of transverse femoral fracture in a sugar glider successfully managed through intramedullary pinning. A 60-gram female intact sugar glider was diagnosed with a closed transverse diaphyseal femoral fracture. Open reduction and intramedullary pin fixation using a 0.8 mm pin was performed. Post-operative management emphasized environmental modification with a flat-walled enclosure to restrict movement and close monitoring. The pin was removed after 70 days with clinical union of the fracture and return of normal limb function. Although intramedullary pinning alone is considered insufficient to control rotational and shearing forces in small animal orthopaedics, this case suggests that such limitations may not fully apply in sugar gliders. Surgical decisions were influenced by species-specific anatomical and behavioural constraints, and housing modification functioned as an adjunct stabilizing strategy. This report highlights the need for further research into the biomechanics of small exotic mammals and subsequent case series of orthopaedic cases in sugar gliders.","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"50 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mineral and heavy metal content in canned tuna: Implications for veterinary public health and consumer safety. 金枪鱼罐头中的矿物质和重金属含量：对兽医公共卫生和消费者安全的影响。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-29 DOI: 10.1007/s11259-026-11228-x

Nermin Rüstemli, Rabia Mehtap Tuncay

引用次数: 0

Clarifying the effects of copper and cadmium stress on sea bass (Dicentrarchus labrax): implications for tissue bioaccumulation, stress biomarkers, and antioxidant-immune-related genes. 阐明铜和镉胁迫对黑鲈的影响：对组织生物积累、应激生物标志物和抗氧化免疫相关基因的影响。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-28 DOI: 10.1007/s11259-026-11215-2

Mahmoud Radwan, Moussa A Moussa, Mohamed Fares, Wafa Abdullah I Al Megrin, Shahd Yassir, Mohammad R K Abdel-Samad

引用次数: 0

Use of peptide nucleic acid fluorescent in situ hybridization technique in the detection of Mycobacterium avium paratuberculosis in fecal samples from dairy herds. 应用肽核酸荧光原位杂交技术检测奶牛粪便中禽分枝杆菌副结核。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-27 DOI: 10.1007/s11259-026-11211-6

Pallvi Slathia, Deepti Narang, Mudit Chandra, Siddhartha Deshmukh, Leishangthem Geeta Devi, Kuldip Gupta

引用次数: 0

Visual and microscopic lesions of enteritis in slaughtered swine: pathogen identification and antimicrobial resistance implications. 屠宰猪肠炎的视觉和显微病变：病原体鉴定和抗菌素耐药性意义。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-27 DOI: 10.1007/s11259-026-11200-9

Luisa Zasso Neis, Rogério Oliveira Rodrigues, Angélica Cavalheiro Bertagnolli, Karine Ludwig Takeuti, Fabiana Quoos Mayer

{"title":"Visual and microscopic lesions of enteritis in slaughtered swine: pathogen identification and antimicrobial resistance implications.","authors":"Luisa Zasso Neis, Rogério Oliveira Rodrigues, Angélica Cavalheiro Bertagnolli, Karine Ludwig Takeuti, Fabiana Quoos Mayer","doi":"10.1007/s11259-026-11200-9","DOIUrl":"10.1007/s11259-026-11200-9","url":null,"abstract":"Efficient, high-quality production is essential to the swine industry, with carcass inspection by health authorities playing a crucial role in detecting abnormalities that may lead to condemnation, including enteritis. Enteritis is, usually, characterized by changes in color, mucosal integrity, intestinal wall thickness and luminal contents and has a multifactorial etiology. This study assessed and classified visual lesions attributed to enteritis and to seek for associations with known pathogens. A scoring system was applied to classify visual changes, and 30 condemned intestines were categorized as mild (< 10 points), moderate (11-20 points), or severe (> 20 points). Laboratory analyses included histopathology; isolation and antimicrobial susceptibility testing of Escherichia coli and Salmonella spp.; and molecular detection of porcine circovirus type 2 (PCV2), Lawsonia intracellularis, Brachyspira pilosicoli, and Brachyspira hyodysenteriae. Lesions were classified as mild (23%), moderate (57%), and severe (20%). PCV2 and L. intracellularis DNA were detected in 60% and 23% of samples, respectively. E. coli was isolated from 57% of intestines, of which 87% exhibited antimicrobial resistance and 56% were multidrug-resistant. No samples tested positive for Salmonella spp., B. pilosicoli, or B. hyodysenteriae. Lower condemnation scores were associated with the presence of PCV2 DNA, mild lesions, and lymph nodes showing necrosis and follicular depletion. Mild lesions were also associated with a lower frequency of multidrug-resistant E. coli. The high prevalence of antimicrobial resistance is concerning from a One Health perspective. These findings underscore the importance of pathogen monitoring, antimicrobial stewardship, and strong animal welfare practices within the swine production chain.","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"50 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13121305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Propylparaben exposure induces hematobiochemical alterations, genotoxicity oxidative stress and apoptosis in Labeo rohita. 对羟基苯甲酸丙酯暴露可诱导血生化改变、遗传毒性、氧化应激和细胞凋亡。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-27 DOI: 10.1007/s11259-026-11230-3

Hasnain Akmal, Shabbir Ahmad, Muhammad Ahsan Riaz, Farhat Jabeen, Shahid Sherzada, Khurram Shahzad

{"title":"Propylparaben exposure induces hematobiochemical alterations, genotoxicity oxidative stress and apoptosis in Labeo rohita.","authors":"Hasnain Akmal, Shabbir Ahmad, Muhammad Ahsan Riaz, Farhat Jabeen, Shahid Sherzada, Khurram Shahzad","doi":"10.1007/s11259-026-11230-3","DOIUrl":"https://doi.org/10.1007/s11259-026-11230-3","url":null,"abstract":"Propylparaben, a frequently used preservative in cosmetics, medicines, and food items, has gained attention due to its extensive prevalence and possible ecological consequences. This research has been conducted to assess the impacts of propylparaben on hematobiochemical parameters, histopathology, oxidative stress, antioxidant enzyme activity, genotoxicity and apoptosis regulatory gene expression in Labeo rohita. Fish were exposed to three concentrations (3 mg/L, 6 mg/L, and 10 mg/L) of propyl paraben for 21 days. Results revealed significant alterations in hematobiochemical parameters. Alterations were observed in the soft tissues of fish, for example, the liver, kidneys, and gills. The gills exhibit lamellar lifting damaged epithelial tissues, deformities in bone cells, and oedema. The liver displayed elongated tubules, sinusoidal spaces, and melano-macrophages, while the kidney displayed sinusoidal spaces, necrosis, and pyknotic nuclei. Propyl paraben causes oxidative stress by inhibiting the activity of enzymes that function as antioxidants, including superoxide dismutase (SOD), glutathione reductase (GR), catalase (CAT) and Peroxidase (POD). Comet assay reported DNA damage in red blood cells (RBCs) of fish. Gene expression study indicated decreased expression of the anti-apoptotic gene Bcl-2 and increased expression of the pro-apoptotic gene Bax, indicating that apoptosis in tissues causes cell death. These results indicated that propyl paraben is potentially genotoxic, causes tissue damage, alters biochemical parameters, induces oxidative stress and regulate apoptosis gene expression.","PeriodicalId":23690,"journal":{"name":"Veterinary Research Communications","volume":"50 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitral annular plane systolic excursion to left atrial volume ratio as a novel index to assess ventricular filling pressure in dogs with myxomatous mitral valve disease. 二尖瓣黏液瘤病犬二尖瓣环平面收缩偏移与左房容积比评价心室充盈压力的新指标。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-27 DOI: 10.1007/s11259-026-11234-z

Jeff M Perez, Jorge Isidoro Matos, Oscar Monge-Utrilla, Pablo Fernandez-Rodriguez, Soraya Falcon-Cordon, Javier Engel-Manchado

引用次数: 0

Owner-reported prevalence and severity of fear and anxiety in dogs. 主人报告的狗的恐惧和焦虑的流行程度和严重程度。

IF 2 3区农林科学

Veterinary Research Communications Pub Date : 2026-04-25 DOI: 10.1007/s11259-026-11227-y

Bonnie V Beaver

引用次数: 0