Voprosy pitaniia最新文献

{"title":"[The role of indole-3-carbinol and epigallocatechin-3-gallate in maintaining men's health (a systematic literature review)].","authors":"K A Sokolov, A V Tsareva","doi":"10.33029/0042-8833-2026-95-3-117-128","DOIUrl":"https://doi.org/10.33029/0042-8833-2026-95-3-117-128","url":null,"abstract":"<p><p>Benign prostatic hyperplasia (BPH) is a condition that impairs the quality of life and occurs with high frequency in older men. Prostate cancer is one of the most common malignancies in men, characterized by high mortality rates. The aim of the study was to systematize data on the physiological effects and safety profile of the supplement Indigal® containing indole-3-carbinol (I3C) and epigallocatechin-3- gallate (EGCG) to confirm their positive impact on men's health and safety.</p><p><strong>Material and methods: </strong>A search for studies on the clinical effect of I3C, its metabolite diindolylmethane (DIM), green tea catechins (GTC), including EGCG, and their combinations was conducted in the database PubMed, Cochrane Library, ClinicalTrials. gov, WHO ICTRP and eLibrary. The final analysis included 31 publications.</p><p><strong>Results: </strong>The review presents current data on the role of I3C and GTC in maintaining men's health. I3C promotes normal hormonal balance, exhibits antiproliferative and antiandrogenic activity, and improves urodynamics and microcirculation in the prostate gland. GTC have demonstrated a chemopreventive effect regarding the risk of prostate cancer, improved regulation of carbohydrate and lipid metabolism, enhanced energy metabolism, and a beneficial impact on vascular health and cellular vital processes. The supplement Indigal® helps reduce the severity of BPH symptoms, improves urodynamic parameters, normalizes the hormonal profile, and exhibits antiproliferative activity along with beneficial effects on microcirculation. Thus, the supplement can reduce the severity of prostatic intraepithelial neoplasia (PIN) and BPH, improves metabolic processes, increases the body's adaptive capacity, and provides protection at the cellular level.</p><p><strong>Conclusion: </strong>The administration of the complex can be recommended as a dietary supplement, a source of I3C and EGCG, for the support of men's health.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"95 3","pages":"117-128"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148702349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The combined effects of sublingual immunotherapy and Lactobacillus acidophilusproducing extract on cedar pollinosis symptoms].","authors":"I Hirobumi, Y Sasuga","doi":"10.33029/0042-8833-2025-94-1-131-139","DOIUrl":"https://doi.org/10.33029/0042-8833-2025-94-1-131-139","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Introduction&lt;/b&gt;. Sublingual immunotherapy (SLIT), in which standardized cedar pollen extract solution is administered, has been used to treat cedar pollinosis, but SLIT is problematic because it takes a long time to become effective, and some cases are ineffective even after long-term treatment. It has also been reported that lactobacillus acidophilus extract (LEX), a food-derived ingredient, alleviates various allergic symptoms. This study examined the usefulness of LEX as a treatment for cedar pollinosis in comparison with SLIT. We also examined whether the combined use of SLIT and LEX could have an early-onset of therapeutic effect on cedar pollinosis. We also examined the usefulness of LEX as a salvage therapy for patients who failed to respond to SLIT. Subjects and methods. Fifteen patients with cedar pollinosis were divided into three groups. The three groups were: three patients in the standardized cedar pollen extract group (S group), seven patients in the lactobacillus-producing extract group (L group), and five patients in the combination group of standardized cedar pollen extract and lactobacillus-producing extract (SL group). The subjects were treated for three years, corresponding to the three scattering seasons of cedar pollen, and observed according to the evaluation items. The evaluation items were severity score based on examination findings, subjective symptom score (QOL score) based on the Japanese Standard QOL Questionnaire for Allergic Rhinitis ( JRQLQ No. 1) questionnaire, nonspecific IgE level measurement by blood test, and cedar pollen-specific IgE level measurement. &lt;b&gt;Results&lt;/b&gt;. After three years of observation, there were no significant differences in severity score and nonspecific IgE levels among the three groups, while QOL score decreased significantly between the first and third years of treatment in the L group. Cedar pollenspecific IgE levels in the S and SL groups showed an increase in the first year and a gradual decrease in the second and third years of treatment compared to the pre-treatment period. In group L, no increase was observed in the first year, and a significant decrease was observed in the second and third years during the cedar pollen dispersal period. &lt;b&gt;Conclusion&lt;/b&gt;. The results of severity and quality of life scores indicated that it took three years of treatment for the S and SL groups to show efficacy, while the L group showed improvement in quality of life scores and cedar pollen-specific IgE levels from the first year, suggesting that LEX is useful as a treatment for cedar pollinosis. The efficacy of combination therapy with SLIT and LEX was not clear, but since the effect of LEX was observed from the early stage of treatment, it was thought that the combination therapy with LEX intake from the early stage of treatment may be effective in reducing the incidence of ineffective cases. The combination therapy of SLIT and LEX may also be useful as a salvage therapy. &lt;b&gt;Categories&lt;/","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 1","pages":"131-139"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A study on nutrition habits and weight loss practice methods in wrestlers].","authors":"E Canbolat, F P Cakiroglu","doi":"10.33029/0042-8833-2025-94-3-111-119","DOIUrl":"10.33029/0042-8833-2025-94-3-111-119","url":null,"abstract":"<p><p>Today, the use of dietary supplements and unhealthy weight loss methods is becoming increasingly common, particularly among athletes who compete in weight-class sports like wrestling. <b>The aim</b> of this study was to investigate the eating habits and weight cutting methods of wrestlers. <b>Material and methods</b>. The descriptive and cross-sectional study was conducted in 96 male wrestlers between the ages of 18-30 years who have been wrestling for at least 3 years. The participants' dietary habits, fluid consumption, nutritional supplement use, pre- and post-training eating habits and weight cutting methods were collected by faceto- face interview method with a questionnaire form. <b>Results</b>. Most participants (70.8%) consumed three main meals a day, but only 37.5% had one snack a day. The reasons for skipping meals were lack of time (41.8%) and lack of habit (19.0%). Among the wrestlers, 33.3% used nutritional supplements and usually due to the influence of the coach (50.0%) or their own will (46.9%). In addition, 61.5% of the athletes practiced certain weight cutting methods, and the most common methods were excessive activity (43.8%), low-calorie diet (37.5%) and sweating in sauna/ham (36.5%). Although the use of nutritional supplements and weight cutting methods was more common in wrestlers who were in the national team and had a ranking (more successful wrestlers), the differences were not statistically significant (p>0.05). <b>Conclusion</b>. Since regular and balanced nutrition and the application of healthy methods of weight reduction not only maintain the health and performance of athletes, but also reduce the risk of injury, it is essential to educate athletes in terms of nutrition and health.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 3","pages":"111-119"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Small intestinal bacterial overgrowth in gastrointestinal diseases - a consequence or a cause of progression?]","authors":"M V Chernogorova, E A Medvedeva, G L Yurenev, G G Maryin, T E Tomenko","doi":"10.33029/0042-8833-2025-94-2-5-17","DOIUrl":"10.33029/0042-8833-2025-94-2-5-17","url":null,"abstract":"<p><p>The prevalence of small intestinal bacterial overgrowth (SIBO) is increasing worldwide, especially in countries with high rates of urbanization. The growth of pathogenic and/or opportunistic bacteria in the small intestine can cause clinical symptoms and digestive and absorption disorders. <b>The aim</b> of the review was to analyze available literature on SIBO in various gastrointestinal pathologies. <b>Material and methods</b>. A literature search was conducted for the last 10 years using the library platforms PubMed, Medscape by keywords: \"small intestinal bacterial overgrowth\", \"SIBO\". A total of 1112 scientific papers were found, of which 124 English-language and 28 Russian-language publications were subject to analysis. Of these, 41 articles (including 5 Russian-language ones) corresponding to the topic of this review were included in the review. <b>Results</b>. The article presents data reflecting the pathophysiology and factors contributing to the development of SIBO. It is shown that irritable bowel syndrome (IBS), inflammatory bowel disease (IBD) and a number of organic and functional diseases of the gastrointestinal tract (GIT) are closely associated with SIBO. The features of the pathogenesis of SIBO in gastrointestinal diseases (IBS, IBD, functional dyspepsia, celiac disease, non-alcoholic steatohepatitis, chronic pancreatitis, etc.) and its influence on the course of gastrointestinal pathology are described. <b>Conclusion</b>. It is impossible to unambiguously assess the influence that SIBO and various types of gastrointestinal pathology have on each other, since, on the one hand, SIBO can develop as a result of gastrointestinal diseases, and on the other hand, it can serve a predictor of the deterioration of these diseases. Most likely, we are talking about the emergence of a vicious circle, to break which it is necessary to eradicate the microorganisms that cause SIBO. This can be achieved both through drug treatment and by adjusting the diet of patients. An important element of non-specific prevention of SIBO is also timely rational treatment of gastrointestinal diseases that contribute to the development of this syndrome.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 2","pages":"5-17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Main milestones in the development of nutrition science (on the 95th anniversary of the Federal Research Center for Nutrition and Biotechnology and the anniversary of the journal Voprosy Pitaniia)].","authors":"V A Tutelyan, D B Nikityuk","doi":"10.33029/0042-8833-2025-94-4-6-26","DOIUrl":"10.33029/0042-8833-2025-94-4-6-26","url":null,"abstract":"<p><p>This year marks the 95th anniversary of the Federal Research Center of Nutrition, Biotechnology and Food Safety (formerly the Institute of Nutrition) and the 93rd anniversary of the founding of the journal \"Voprosy Pitaniia\". The main areas of activity were the study of the chemical composition of the diet, the nutritional epidemiology in various groups of the Russian population (children, pregnant and lactating women, the elderly, athletes), food and noval food safety, as well as the development of therapeutic diets for various diseases and food for special dietary uses for different groups of the population. Throughout all these years, the latest scientific achievements of the Institute's staff and other outstanding specialists in the field of optimal and therapeutic nutrition have been published in the journal \"Voprosy Pitaniia\".</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 4","pages":"6-26"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of the combined effect of <i>Arthrospira</i> platensis biomass phycyanin concentrate and soy protein on male Wistar rats fed a high-fat diet with added cholesterol].","authors":"N A Biryulina, Yu S Sidorova, S N Zorin, N A Petrov, G V Guseva, V K Mazo, A A Kochetkova","doi":"10.33029/0042-8833-2025-94-2-73-84","DOIUrl":"10.33029/0042-8833-2025-94-2-73-84","url":null,"abstract":"&lt;p&gt;&lt;p&gt;One of the approaches to the prevention and dietary correction of carbohydrate and lipid metabolism disorders is the development of new functional foods with the ingredients containing bioactive compounds with hypolipidemic and hypoglycemic properties. Soybean protein and biomass of Arthrospira platensis cyanobacteria containing phycobiliproteins (C-phycocyanin and allophycocyanin) are the sources of such bioactive compounds. &lt;b&gt;The aim&lt;/b&gt; of the research was to evaluate the combined effect of phycocyanin concentrate (in two dosages of 30 and 300 mg/kg body weight) and soy protein (50% of the protein in the diet) on disorders, induced in Wistar male rats by consumption of high-fat diet with 2% cholesterol. &lt;b&gt;Material and methods&lt;/b&gt;. A 108-day study was performed on 60 growing male Wistar rats. Animals of the control group K1 received a standard semi-synthetic diet. Disturbances in rats of the experimental group G2 were caused by increasing the proportion of the fat component in the diet (up to 29%), adding 2% cholesterol and replacing 20% of cornstarch with sucrose. In experimental groups G3, G4, and G5, 50% of casein in the high-fat diet was replaced with soy protein isolate. Additionally, phycocyanin concentrate was added to the diets of rats in groups G4 and G5 in quantities of 30 and 300 mg/kg of body weight (in terms of phycocyanin), respectively. In all animals, insulin resistance test was conducted, body composition was measured using magnetic resonance relaxometry, blood serum biochemical parameters of protein, lipid, purine metabolism and liver function, and the triglyceride and cholesterol liver levels were determined by spectrophotometric methods using a biochemical analyzer; leptin, ghrelin, C-peptide, insulin, malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase and hydroperoxides were determined in blood serum using enzyme immunoassay. &lt;b&gt;Results&lt;/b&gt;. The inclusion of only soy protein isolate into the high-fat diet with cholesterol had a hypoglycemic effect, preventing the development of insulin resistance, and led to a reliable decrease in blood level of lipid peroxides (p=0.011) compared to G2 group. The combined introduction of phycocyanin concentrate at a dose of 300 mg/kg body weight and soy protein into the diet significantly reduced blood levels of cholesterol (p=0.022), lipid peroxides (p=0.001) and ALT activity (p=0.032) compared to G2. At the same time, animals of both these groups retained disorders in hormonal status (increased leptin and ghrelin level), antioxidant status (elevated level of MDA and SOD) at the same level as for animals consuming high-fat diet with 2% cholesterol. Phycocyanin concentrate at a dosage of 30 mg/kg body weight together with soy protein in the diet prevented the development of insulin resistance (p=0.049) and reduced serum glucose level (p=0.025); exerted an antioxidant effect, normalizing the level of lipid peroxides (p=0.047), MDA (p=0.015) and SOD (p=0.038), s","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 2","pages":"73-84"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism].","authors":"E N Trushina, N A Rieger, O K Mustafina, A N Timonin, I V Aksenov, A G Krasutsky, V A Tutelyan, D B Nikityuk","doi":"10.33029/0042-8833-2025-94-2-61-72","DOIUrl":"10.33029/0042-8833-2025-94-2-61-72","url":null,"abstract":"&lt;p&gt;&lt;p&gt;The quest for new bioactive compounds with an immune-oriented focus, as well as the study of the mechanisms of immunotropic action of the plant adaptogens used to restore and strengthen the immune system in athletes after intense physical exertion is a priority area of the research in sports medicine. &lt;b&gt;The aim&lt;/b&gt; of the study was to investigate the effect intragastric administration of ginseng root extract (GRE) (ginsenosides) on immunity and regulation of energy metabolism in rats after exhausting physical exercise (EPE). &lt;b&gt;Material and methods&lt;/b&gt;. The study was conducted on 5 groups of male Wistar rats with an initial body weight of ≈250 g. Animals of the control (the 1st) and experimental groups were placed on a treadmill for 20 min 3 times a week for 2 weeks, after the training was completed, an EPE test was performed (except for the control). 30 min before the training and EPE, rats of groups 3-5 were intragastrically administered GRE in physiological solution at doses of 2.7, 13.5 and 27.0 mg per 1 kg of body weight in terms of ginsenosides, respectively; animals of groups 1 and 2 - physiological solution. Animals were withdrawn from the experiment within 30 min after the cessation of EPE. Expression of CD45R, CD3, CD4, CD8a, CD161 receptors on rat peripheral blood lymphocytes was determined by direct immunofluorescence staining of whole blood cells using a panel of monoclonal antibodies on an FC-500 flow cytometer. A basic commercial kit was used to determine the levels of cytokines: interferon γ (IFN-γ), interleukin 1β (IL-1β), IL-4, IL-6, IL-10, IL-17A and tumor necrosis factor α (TNF-α), hormones leptin and ghrelin. Measurements were performed on a Luminex 200 multiplex analyzer using xMAP (multianalyte profiling) technology and Luminex xPONENT Version 3.1 software. &lt;b&gt;Results&lt;/b&gt;. EPE in rats caused changes in the composition of lymphocyte subpopulations, manifested in an increase in the relative content of CD8+ cytotoxic lymphocytes in the peripheral blood with a decrease in the immunoregulatory index (СD4+/CD8+). Increased plasma levels of pro-inflammatory cytokines (IL-17A and TNF-α) found in group 2 rats after EPE indicate the presence of inflammatory processes in damaged organs and tissues, including skeletal muscles. Intragastric administration of ginseng root extract to rats had a dose-dependent protective effect, as evidenced by normalization of the composition of lymphocyte subpopulations, a decrease in the levels of pro-inflammatory cytokines, an increase in the activity of Treg (regulatory T-lymphocytes) and Th2 (T-helpers type 2) with an increase in the production of IL-10 and IL-4, positive modulation of the IL-10/ IL-17A ratio and restoration of the overall cytokine profile to control values. Ginseng root extract also has a positive effect on energy metabolism, in which regulation leptin and ghrelin participate. Administration of the maximum dose of ginseng root extract (27 mg/kg body weight) to rats induced ac","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 2","pages":"61-72"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The radiation decontamination detecting in commercial spices marketed in Russia: interpreting the spectra of electron paramagnetic resonance].","authors":"D I Titova, I M Medzhidov, V A Kharlamov","doi":"10.33029/0042-8833-2025-94-6-58-68","DOIUrl":"10.33029/0042-8833-2025-94-6-58-68","url":null,"abstract":"<p><p>To increase shelf life and reduce microbial contamination, spices, widely used for a variety of purposes (coloring and preserving agents, flavor enhancers), are regularly subjected to radiation decontamination before subsequent sale and use by consumers. Although spices are consumed only in small amounts, it's important to note that they are added to a wide variety of foods, including ready-to-eat ones. Therefore, assessing the spice radiation decontamination fact of spices is relevant. The aim of the study was to apply electron paramagnetic resonance (EPR) spectra to identify the fact of radiation decontamination of finished foods (spices), to assess the signal intensity varies depending on the absorbed dose and attenuation kinetics of the spectra signal over time.</p><p><strong>Material and methods: </strong>Samples of dry spices (ginger, ground cinnamon, and turmeric) were irradiated with 60Со ɣ-rays at absorbed doses of 1, 3, 5, 7 and 10 kGy. For the irradiated and control samples, spectra were recorded on an electron paramagnetic resonance spectrometer and signals were detected. Spectra were recorded immediately after irradiation and after 7, 14, 28, 90, 180 and 270 days.</p><p><strong>Results: </strong>The G-factor was 2.0042 for all spice spectra, indicating the carbon-containing radicals' presence. The EPR signal intensity increased with radiation dose elevation, confirming raise in the level of the presented paramagnetic centers. After 1-10 kGy radiation treatment, the signal intensity increased by 87-527% for ginger, by 110-657% for ground cinnamon and by 252-826% for turmeric. The kinetics of signal attenuation demonstrated a significant decrease in intensity during the first 14 days after irradiation of all the tested spices, with subsequent slower attenuation over the next 9 months. The signal intensity attenuation was maximal in the first 7 days for ginger (37-60%), for ground cinnamon (48-72%), as for turmeric (47-71%).</p><p><strong>Conclusion: </strong>After the γ-radiation treatment of the spices, oxidative processes occur and free radicals were formed, as indicated by the recorded EPR signals. Irradiated samples were clearly differed from control, allowing for the separation of radiationtreated samples from untreated. Treatments at 1-10 kGy could been differentiated based on the signal's intensity. EPR spectra assessment can be used to determine the fact of radiation treatment and, therefore, for radiation monitoring on the Russian consumer market for mono-component spices.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 6","pages":"58-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145990999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Hygienic assessment of the levels of β-cryptoxanthine intake from food sources].","authors":"E V Kirpichenkova, A A Korolev, E I Nikitenko, E L Denisova, E A Fanda, G G Onishchenko","doi":"10.33029/0042-8833-2025-94-2-52-60","DOIUrl":"10.33029/0042-8833-2025-94-2-52-60","url":null,"abstract":"<p><p>β-Cryptoxanthin, along with β-carotene and α-carotene, is a precursor to vitamin A, which plays an important physiological role in the body. β-Cryptoxanthin is found in significant amounts in a limited number of dietary sources. The highest levels of β-cryptoxanthin are found in yellow, orange and red vegetables and fruit (persimmons, papaya, sweet peppers, tangerines, corn, peaches, oranges, etc.). <b>The aim</b> of this study was to perform a hygienic assessment of β-cryptoxanthin intake levels, identify its main food sources in young adults in the summer-autumn period. <b>Material and methods</b>. An online questionnaire was developed to establish β-cryptoxanthin intake levels from dietary sources. The questionnaire contained a list of products containing β-cryptoxanthin and common in the Russian food market. Respondents indicated the portion of food consumed the day before the survey. Data collection was carried during the period from June to October 2023. The study involved 214 respondents (173 women and 41 men) aged 18-35 years (mean age 23.4±5.2 years). <b>Results</b>. The average β-cryptoxanthin intake was 0.58±0.63 (Me=0.21 [0.03; 0.66]) mg/ day. At the same time, only 15.4% of respondents had an intake more than 1.0 mg/day, which was ensured both by a variety of food sources in the diet (from 3 to 6 items) and by inclusion individual products with high content of β-cryptoxanthin. The preferred sources of β-cryptoxanthin for the majority of respondents in groups with high dietary levels (more than 1.5 mg/day) were sweet red peppers, peaches, watermelon, tangerines and orange juice. In groups with low and minimal levels of β-cryptoxanthin (less than 1.0 mg/day), along with the indicated products, its intake was due to the consumption of red pepper and paprika spices, dried cilantro, yellow and green sweet peppers, hot pepper sauce, canned jalapeno peppers, corn, oranges, apricots, nectarines, plums, peach and watermelon juices, canned peaches, dried papaya, potato chips. Despite the diversity of dietary sources, low and minimal levels of β-cryptoxanthin intake were due to both insufficient intake and selection of foods with low β-cryptoxanthin content per serving. <b>Conclusion</b>. In 15.4% of respondents, the daily intake of β-cryptoxanthin was more than 1.0 mg/day, in 65.4% of respondents it was less than 1.0 mg/day, and in 19.2% of participants there were no sources of β-cryptoxanthin in the diet. More often than others, sweet red pepper, orange juice, and paprika and red pepper spices were present in the diet of respondents, regardless of the level of β-cryptoxanthin intake, but their contribution to the intake of β-cryptoxanthin was determined by the volume of a single serving, and therefore spices cannot be considered priority sources.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 2","pages":"52-60"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The influence of vitamin D status on anxiety and depression in students in different seasons of the year].","authors":"A V Tarasov, R S Rakhmanov, N A Skoblina, E S Bogomolova","doi":"10.33029/0042-8833-2025-94-5-151-158","DOIUrl":"https://doi.org/10.33029/0042-8833-2025-94-5-151-158","url":null,"abstract":"<p><p>The academic demands and lifestyle of university students contribute to the development of stress, anxiety, and depression, with micronutrient deficiencies, including vitamin D insufficiency, among the contributing risk factors. The aim of the research was to evaluate the impact of vitamin D status on anxiety and depression in students by season.</p><p><strong>Material and methods: </strong>A study was conducted in September-October (n=100, including 64 girls and 36 boys) and April-May (n=94, including 70 girls and 24 boys) among students of 1st-5th years. Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS), with scores ≤7 indicating no clinically significant symptoms, 8-10 - subclinical symptoms, and ≥11 - clinically significant symptoms. Plasma 25-hydroxyvitamin D [25(OH)D] levels were measured using ELISA.</p><p><strong>Results: </strong>Anxiety and depression were recorded in 25.0 and 11.0% of students in autumn, increasing to 50.0 and 29.8% in spring, respectively. In spring, the prevalence of clinically significant anxiety (from 6.0±2.5 to 25.5±4.5%, p=0.001) and subclinical depression (from 9.0±3.0 to 24.5±4.3%, p=0.001) rose. Median 25(OH)D level was 1.9-fold lower in spring than in autumn (10.16 [8.02; 13.85] vs 19.16 [16.41; 22.90] ng/ml, р<0.001) with no significant gender differences. The prevalence of severe deficiency increased 9.6-fold in spring, while insufficiency decreased 4.9-fold. In spring, the proportion of students with severe vitamin D deficiency increased from 8.4±3.5 to 54.2±6.7% among males and from 3.1±1.8 to 45.7±7.4% among females, while the prevalence of insufficiency decreased from 33.3±8.1 to 8.4±4.5% and from 37.5±7.9 to 7.1±3.6%, respectively. The correlation between vitamin D status and anxiety scores increased from weak to moderate (r =-0.39 to -0.56), and between vitamin D status and depression scores from very weak to moderate (r =-0.22 to -0.52); all correlations were statistically significant, supporting the role of vitamin D status in the development of these conditions.</p><p><strong>Conclusion: </strong>These findings support the implementation of biochemical screening to identify students with low vitamin D status and the initiation of supplementation at the beginning of the academic year.</p>","PeriodicalId":23652,"journal":{"name":"Voprosy pitaniia","volume":"94 5","pages":"151-158"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145564970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}