Wiadomosci lekarskie最新文献_第4页

Actual scientific data in comorbid periodontal diseases and heart-vessel pathology.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/201340

Zynoviya O Bumbar, Khrystyna A Sichkoriz, Taras I Vykhtiuk, Taras I Pupin

引用次数: 0

Associated gene polymorphism (ABCG2) and drug-resistant in patients with epilepsy.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/200736

Ghada Abd El Wahab Khalil Ibrahim, Maysaa Ali Abdul Khaleq, Ahmed Hamza Ajmi

{"title":"Associated gene polymorphism (ABCG2) and drug-resistant in patients with epilepsy.","authors":"Ghada Abd El Wahab Khalil Ibrahim, Maysaa Ali Abdul Khaleq, Ahmed Hamza Ajmi","doi":"10.36740/WLek/200736","DOIUrl":"https://doi.org/10.36740/WLek/200736","url":null,"abstract":"Objective: Aim: To evaluate useful variations in ABCG2 gene in relation to reaction of epileptic tablets in people with partial epilepsy. Additionally, explore opportunity of blended outcomes of variations in more than one transporter genes.Patients and methods: Materials and Methods: The study included sixty-five sufferers and forty healthful people; there were no top notch versions in phrases of age, gender, antiseizure medication therapy, or precise kinds of prescription drugs used. Polymorphism testing involved DNA extraction from the sample. Data pertaining to studies that examined correlation between ABCG2 polymorphisms were sought out. A total of 105 individuals, 65 of whom were patients and 40 of whom were healthy controls, were enrolled from October 2023 to April 2024 in this case-control research that took place in a hospital setting.Results: Results: Common age of sufferers turned into 22.51 ± 5.89 years, while manage organization had a median age of 19.24 ± 3.77 years. Distribution of sufferers and control individuals had a comparable frequency, with no brilliant disparities in terms of gender, antiseizure drug therapy, or antiseizure remedy kind. The heterozygous genotype CT became observed to be greater commonplace in patients compared to the manage group. The correlation among the ABCG2 C>T poly allele polymorphism and the risk of epilepsy was quite widespread.Conclusion: Conclusions: Overall, the study found that the ABCG2 C>T (rs2231137) polymorphism is associated with an increased risk of epilepsy. Specifically, the patient group was more likely to have the heterozygous genotype CT, with the allele C, compared to the control group.","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"381-387"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nurses' attitudes towards mental illness and home health care quality as a means of managing psychiatric patients' relapses and re-admissions: a quasi -experimental study.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/199813

Amal Ibrahim Khalil, Manni Alharbi, Reem Alsulami, Manar Alotaibi

{"title":"Nurses' attitudes towards mental illness and home health care quality as a means of managing psychiatric patients' relapses and re-admissions: a quasi -experimental study.","authors":"Amal Ibrahim Khalil, Manni Alharbi, Reem Alsulami, Manar Alotaibi","doi":"10.36740/WLek/199813","DOIUrl":"10.36740/WLek/199813","url":null,"abstract":"Objective: Aim: This study aims to assess the impact of an educational intervention on nurses' knowledge and attitudes regarding home health care, relapse management, and psychiatric hospital admissions.Patients and methods: Materials and Methods: A quasi-experimental study was conducted with 106 nurses at Erada for Mental Health and Addiction. Standardized assessment tools, including a knowledge scale for home health care quality and a mental illness devaluation scale, were used.Results: Results: Most participants were female 78.4% with a bachelor's degree 77%, and the average age was 2.06±.954. The analysis revealed a significant improvement in knowledge levels post-intervention P<0.000, however, there was a slight non-significant increase in devaluation scale scores after the intervention (pre-24.55±2.96, post-25.18±3.45).Conclusion: Conclusions: Targeted interventions to enhance nurses' knowledge of home health care quality and promote positive attitudes toward mental illnesses can lead to improved patient care, potentially reducing relapses and readmissions among psychiatric patients. Future research should explore the long-term impact and sustainability of such interventions in mental health care settings.","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 1","pages":"16-27"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calcium pyrophosphate dihydrate deposition disease (chondrocalcinosis): a review.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/200864

Andrzej Żyluk

引用次数: 0

Case of early uncomplicated multivascular nonobstructive coronary atherosclerosis in young male: novel aspects of noninvasive diagnostic.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/197140

Yuliya Tyravska, Oleksandr Savchenko, Iryna Melnychuk, Viktor Lizogub

引用次数: 0

Medical confidentiality as an element of privacy vs. public interest in crime disclosure: striving for balance.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/197335

Dariia Abbasova, Olga Tyshchenko, Ivan Titko

{"title":"Medical confidentiality as an element of privacy vs. public interest in crime disclosure: striving for balance.","authors":"Dariia Abbasova, Olga Tyshchenko, Ivan Titko","doi":"10.36740/WLek/197335","DOIUrl":"https://doi.org/10.36740/WLek/197335","url":null,"abstract":"Objective: Aim: This article aims to raise awareness and stimulate scientific discussion on the issue of protecting medical confidentiality during criminal proceedings, with the goal of further improving legal tools to ensure compliance with the standards of the European Court of Human Rights (hereinafter referred to as the ECHR) in this field.Patients and methods: Materials and Methods: In preparing the article, the following issues were addressed: the provisions of international legal acts; the legal positions of the ECHR related to the protection of medical confidentiality in criminal proceedings; and scientific research in this field. The methodological basis of the research includes the method of generalization, methods of analysis and synthesis.Conclusion: Conclusions: The right to confidentiality regarding health status may be restricted during criminal procedural activities in forms prescribed by law. Such a restriction will be considered lawful and justified in a democratic society, provided that the interference meets the set of criteria established by the practice of the ECHR. The storage of biological material outside the scope of criminal proceedings is, in some cases, justified to safeguard public interests in a democratic society; however, under certain conditions, it may conflict with the principles of the presumption of innocence and the right to privacy.","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"448-455"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The association between chronic diseases and lifestyle: A comparative study between two groups.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/201199

Ahmed D Salman, Zahid J Mohammed

引用次数: 0

The regional burden of acute pancreatitis in Ukraine: current trends in incidence, etiology, morbidity, gender distribution and mortality.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/200414

Tetiana Formanchuk, Ulrich Friedrich Wellner, Andrii Formanchuk, Hryhoriy Lapshyn

{"title":"The regional burden of acute pancreatitis in Ukraine: current trends in incidence, etiology, morbidity, gender distribution and mortality.","authors":"Tetiana Formanchuk, Ulrich Friedrich Wellner, Andrii Formanchuk, Hryhoriy Lapshyn","doi":"10.36740/WLek/200414","DOIUrl":"https://doi.org/10.36740/WLek/200414","url":null,"abstract":"Objective: Aim: The aim of the study was to analyze trends in incidence, etiology, gender distribution, morbidity and mortality for acute pancreatitis and to determine whether they correspond to the world trends and to identify changes in trends under the influence of the circumstances of recent years, in particular the COVID-19 pandemic and the full-scale war unleashed by Russia on the territory of Ukraine.Patients and methods: Materials and Methods: The retrospective study of the prospectively maintained data base of the incidence rate dynamics, mortality, age and gender distribution of AP at the regional level in the period from 2011 to 2022 was done. The data were obtained from the statistics services of the regional healthcare department and two clinical hospitals, Vinnytsia, Ukraine.Results: Results: Over the past 12 years, 18715 patients with AP have been treated at the regional level. Annually, 1559±259 people require inpatient treatment for this pathology, with an average annual length of hospital stay of 10850±856 days. The incidence rate of AP in 2022 consisted 134,4 cases/100000 population. During the studied period, the population of the region decreased by 8,02%. On the other hand, there is an increase in cases of AP, namely, in 2022, the number of patients with acute pancreatitis reached 177,83% from the level of 2011. There was also an increase in overall mortality from AP from 1,7% to 2,2%.Conclusion: Conclusions: During the 12-year period under study, against the background of a decrease in the average population at the regional level, there was a tendency for the incidence and mortality of AP to increase.","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"353-366"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Сonnection and assessment of the psychological status of orthodontic patients with various types of malocclusion.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/197129

Oleksiy A Stasyuk, Vira Kuroiedova, Kira Sedykh, Yuliya Sokolohorska-Nykina, Yevhenii Vyzhenko, Liudmila Halych, Pavlo Korobov

{"title":"Сonnection and assessment of the psychological status of orthodontic patients with various types of malocclusion.","authors":"Oleksiy A Stasyuk, Vira Kuroiedova, Kira Sedykh, Yuliya Sokolohorska-Nykina, Yevhenii Vyzhenko, Liudmila Halych, Pavlo Korobov","doi":"10.36740/WLek/197129","DOIUrl":"https://doi.org/10.36740/WLek/197129","url":null,"abstract":"Objective: Aim: Assessment of relationship between the psychological status of orthodontic patients and the type of malocclusion using the Eysenck Personality Questionnaire.Patients and methods: Materials and Methods: Interviews were conducted using the Eysenck test. After the survey, the results of the questionnaire were analyzed according to the openness scale and 206 people aged 12 to 38 years were included in the further study. All patients were divided into groups according to the classification of malocclusion according to Angle - I, II and III class.Results: Results: During the verification of the first hypothesis regarding the relationship between patients with malocclusion and the level of neuroticism, a relationship was established in patients with II class (χ2=8.87, p=0.064). When establishing a relationship between patients with different classes of malocclusion and personality traits, no correlations were found (χ2=1.72, p=0.787). According to the results of the Pearson's Chi-square analysis, a relationship was established between patients with different classes of malocclusion and types of temperament (χ2=32.0 p=0.004).Conclusion: Conclusions: According to the results of our research, patients with pathology of III class according to Angle most often have the temperament type of sanguine and melancholic with introverted personality traits, with II class - melancholic and choleric, with I class according to Angle - sanguine and choleric, who are characterized by extraversion traits. According to the psychosocial status, patients with pathology of I and II class correspond to a high level of neuroticism, with III class - to an average level of neuroticism.","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"336-341"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of INSR (rs2229429) G>A genetic polymorphism on response to exogenous insulin in type 1 diabetic Iraqi patients.

Wiadomosci lekarskie Pub Date : 2025-01-01 DOI: 10.36740/WLek/199949

Farah Ali ALQuraishi, Mohammed Ibrahim Rasool

{"title":"Impact of INSR (rs2229429) G>A genetic polymorphism on response to exogenous insulin in type 1 diabetic Iraqi patients.","authors":"Farah Ali ALQuraishi, Mohammed Ibrahim Rasool","doi":"10.36740/WLek/199949","DOIUrl":"10.36740/WLek/199949","url":null,"abstract":"Objective: Aim: To examine prevalence of genotypic distribution, particularly assessing how genetic polymorphisms in Insulin Receptor gene influence effectiveness of insulin therapy in a sample of Iraqi population.Patients and methods: Materials and Methods: Effect of Single Nucleotide Polymorphisms rs2229429 G>A have been investigated in 99 T1DM individuals, with a mean age of 12.3 years. These patients were managed with exogenous insulin through a basal-bolus monotherapy regimen. Genotyping was performed using an allele-specific polymerase chain reaction technique, and the data were statistically analyzed.Results: Results: The prevalence of the minor allele frequency is 12% in a sample of Iraqi population. Homozygous mutant carriers of rs2229429 G>A were 10.479 times at higher risk for developing poor glycemic control (HbA1c >86 mmol/mol) compared to wild genotype in type 1 diabetes mellitus, p=0.008. Ultimately poor responders to exogenous insulin, demonstrating significantly higher plasma insulin receptors levels p<0.001.Conclusion: Conclusions: The investigated Single Nucleotide Polymorphisms is significantly associated with hyperglycemia in type 1 diabetes mellitus and contributes to the development of double diabetes.","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 1","pages":"71-81"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0