Stepan S Filip, Rudolf M Slivka, Andrii M Bratasiuk, Yuriy P Skrypynets, Antonina V Varvarynets
{"title":"Features of clinical flow of traumatic illness on a background chronic stress.","authors":"Stepan S Filip, Rudolf M Slivka, Andrii M Bratasiuk, Yuriy P Skrypynets, Antonina V Varvarynets","doi":"10.36740/WLek/203903","DOIUrl":"10.36740/WLek/203903","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To focus on the dependence of the severity of the clinical features of traumatic illness on stress components and chronic stress in particular.</p><p><strong>Patients and methods: </strong>Materials and Methods: Analysis of data on the results of existing studies assessing the impact of chronic stress on the course of traumatic illness.</p><p><strong>Conclusion: </strong>Conclusions: The introduction of a therapeutic complex of immunotherapy and sedatives for traumatic illness with a pronounced stress component, with the possible development of severe complications, will make it possible to improve the results of treatment and rehabilitation of patients with traumatic illness.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 4","pages":"908-914"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rimma L Skrypnyk, Nataliia A Tykhonchuk, Inna D Skrypnychenko, Alla I Zadorozhna, Nataliia W Zhaboedova, Oksana I Parfonova
{"title":"Effective strategies for the treatment of eyelid diseases in modern ophthalmology.","authors":"Rimma L Skrypnyk, Nataliia A Tykhonchuk, Inna D Skrypnychenko, Alla I Zadorozhna, Nataliia W Zhaboedova, Oksana I Parfonova","doi":"10.36740/WLek/205359","DOIUrl":"https://doi.org/10.36740/WLek/205359","url":null,"abstract":"<p><strong>Objective: </strong>Aim: Investigate the effectiveness of micellar foam containing tea tree oil and Roman chamomile oil in preoperative eyelid sanitation in patients with blepharitis.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study involved 37 patients with blepharitis, aged 28-62. Patients were split into two groups: 22 who used micellar foam preoperatively and 15 who did not. Diagnoses included chronic, seborrheic, and demodicosis blepharitis. Symptoms and signs were monitored over a ten-day treatment period, showing varied responses to micellar foam.</p><p><strong>Results: </strong>Results: The study showed a significant improvement in blepharitis symptoms with the use of foam containing tea tree and Roman chamomile oils. Patients reported reduced dryness, scaling, hyperemia, and itching. Microscopic examination showed disappearance of scales and couplings, and reduced hyperemia. Bacterial contamination decreased significantly, with good tolerance to the treatment.</p><p><strong>Conclusion: </strong>Conclusions: Recent literature and our study indicate that women predominantly suffer from blepharitis, possibly due to their higher medical service utilization. Most cases were mild to moderate, with multifactorial causes and bacterial influence. Eight patients (36.4%) had non-bacterial blepharitis. Understanding blepharitis epidemiology helps in pathogenetically targeted treatment. The innovative micellar foam with tea tree oil and chamomile shows positive results and reduces antibiotic resistance risks.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 5","pages":"1006-1012"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vladyslav Smiianov, Maksim Husenko, Olena Vishnikina, Olena Churikanova, Tetiana Vasylieva
{"title":"The interconnections of different types of fertiliser consumption on disability-adjusted life years of digestive system diseases in European countries.","authors":"Vladyslav Smiianov, Maksim Husenko, Olena Vishnikina, Olena Churikanova, Tetiana Vasylieva","doi":"10.36740/WLek/205403","DOIUrl":"https://doi.org/10.36740/WLek/205403","url":null,"abstract":"<p><strong>Objective: </strong>Aim: This study examines the impact of different fertiliser types - phosphate, nitrogen, and potash -and pesticide use on disability-adjusted life years (DALYs) associated with digestive system diseases in European countries. It focuses on pancreatitis, upper digestive system disorders, and non-alcoholic fatty liver disease (NAFLD), including cirrhosis.</p><p><strong>Patients and methods: </strong>Materials and Methods: Using a balanced panel dataset covering 39 European countries from 2006 to 2021, the study incorporates data from the Global Burden of Disease database (DALYs), the Food and Agriculture Organization (fertiliser and pesticide use), and the World Bank (trade indicators). A fixed-effects regression model was applied to assess the influence of agricultural chemical use and trade dynamics on DALYs.</p><p><strong>Results: </strong>Results: Pesticide use per hectare was significantly associated with higher DALYs for NAFLD, indicating substantial health risks. Nitrogen fertiliser use showed a protective effect against DALYs for upper digestive diseases and pancreatitis. In contrast, excessive potash application was linked to increased DALYs for pancreatitis. The effects of phosphate use varied by disease type. Trade-related interaction terms demonstrated complex and sometimes amplifying effects on health outcomes.</p><p><strong>Conclusion: </strong>Conclusions: Agricultural inputs have both beneficial and adverse health implications. While essential for productivity, their misuse can contribute to chronic disease burdens. The findings highlight the importance of sustainable farming practices and regulatory oversight. Integrating health metrics such as DALYs into agricultural and environmental policy could improve public health outcomes across Europe.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 5","pages":"1176-1183"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valery M Lekhan, Nadiia V Puchkova, Mykola I Zaiarskyi
{"title":"Problems of antimicrobial resistance in the primary health care system (results of the sociological study).","authors":"Valery M Lekhan, Nadiia V Puchkova, Mykola I Zaiarskyi","doi":"10.36740/WLek/205352","DOIUrl":"https://doi.org/10.36740/WLek/205352","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To assess the level of awareness of primary health care physicians regarding the problem of antimicrobial resistance and identify the main obstacles to the rational use of antibiotics in practice.</p><p><strong>Patients and methods: </strong>Materials and Methods: A sociological survey was conducted among primary health care physicians using a specially designed questionnaire containing questions on knowledge, antibiotic prescribing practices, and ways to address the problem of antimicrobial resistance. The survey was conducted in January 2025. Descriptive and analytical statistics were used to analyze the results obtained from 221 respondents.</p><p><strong>Results: </strong>Results: Most respondents (about 90%) encountered cases of antimicrobial resistance in their work. The respondents named the following as the main reasons: the use of antibiotics without a prescription (87.8% of respondents), their excessive use (80.1%), and non-compliance by patients with the course of treatment (77.8%). Analysis of the responses shows that respondents sometimes prescribe antibiotics from the watch and reserve groups (53.4% and 29%, respectively), regularly prescribe antibiotics without a prescription (14%), use injectable antibiotics (21% of respondents); 54.3% note that patients often take antibiotics on their own.</p><p><strong>Conclusion: </strong>Conclusions: The survey results show that antimicrobial resistance is a serious problem in the primary healthcare system. Primary care physicians often do not follow recommendations for selecting and prescribing antibiotics. Effectively solving the problem requires a comprehensive approach, which should include improving antibiotic stewardship, increasing the level of knowledge of medical professionals, and widely informing the population about their proper use.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 5","pages":"981-987"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anzhela B Berzina, Pavlo S Berzin, Ruslan A Volynets, Olga M Koval, Nataliia V Marushchak, Mykhailo B Holovko, Iryna Y Khmil
{"title":"Healthcare fraud in the United States of America and Ukraine: A comparative legal research.","authors":"Anzhela B Berzina, Pavlo S Berzin, Ruslan A Volynets, Olga M Koval, Nataliia V Marushchak, Mykhailo B Holovko, Iryna Y Khmil","doi":"10.36740/WLek/207347","DOIUrl":"https://doi.org/10.36740/WLek/207347","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To conduct a comparative legal study of healthcare fraud in the United States of America and Ukraine.</p><p><strong>Patients and methods: </strong>Materials and Methods: This study is based on the analysis of the US federal regulatory legislation (False Claims Act, Anti-Kickback Statute, Stark Law); data from the Fraud Section of the US Department of Justice for the last five years; case law in Ukraine (more than 30 court verdicts were analysed); data from the National Health Service of Ukraine. Dialectical, hermeneutic, comparative, analytical, synthetic, and systems analysis research methods were used.</p><p><strong>Results: </strong>Results: The criminal legislation acts that provide for criminal liability for healthcare fraud under the laws of the United States and Ukraine are analysed; the criteria for identifying types of healthcare fraud and related criminal offences are defined. It is determined that healthcare fraud has a multidimensional nature, which can manifest itself in different ways, but the common purpose in these manifestations of criminal behaviour is deception or intentional distortion of facts to obtain money or property that is under the control of or owned by any healthcare benefit programme (in the US) or medical guarantees programme (in Ukraine). There are various illegal manipulations with the state programme of medical guarantees. Starting from 2021, the judicial practice of Ukraine lacks a single acceptable approach to the criminal legal assessment of such illegal manipulations.</p><p><strong>Conclusion: </strong>Conclusions: The experience of the United States in determining the types of criminal offences that constitute healthcare fraud and establishing criminal liability for their commission is appropriate to borrow.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 6","pages":"967-973"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oleksandr M Shevchuk, Anatolii M Shevchuk, Olena O Holovash, Oleksandr O Mykhailenko, Arina O Ivanytsia
{"title":"Protection of сhildren's rights to access palliative medical services: Legal problems.","authors":"Oleksandr M Shevchuk, Anatolii M Shevchuk, Olena O Holovash, Oleksandr O Mykhailenko, Arina O Ivanytsia","doi":"10.36740/WLek/207368","DOIUrl":"https://doi.org/10.36740/WLek/207368","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To identify legal issues in protecting children's rights to palliative care in Ukraine, to propose basic guarantees of their rights, and to note trends in foreign practice.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study is based on its theoretical and empirical basis, the system of methods of scientific knowledge. The theoretical basis includes scientific articles, expert analysis of legislation and international organizations.</p><p><strong>Results: </strong>Results: The implementation of children's right to palliative care can be classified as universal and special. In the implementation of this right, children often face inadequate representation of their interests and shortcomings in the provision of medical services to them. As a result, the right of children to quality medical care when receiving palliative care, the right of children to receive palliative care at home, the right of the child to consent to receiving palliative care, the right of children to confidentiality and protection of personal data when receiving palliative care, and the right of children to privacy in this area are violated.</p><p><strong>Conclusion: </strong>Conclusions: Accessibility of children's rights to palliative medical care is an important aspect of ensuring the implementation of one of the fundamental, inalienable human rights to life and health as the highest social values.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 6","pages":"1078-1082"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magdalena Prynda, Mikołaj Mazur, Patrycja Doroz, Olga Odrzywolska, Ali Aboud, Adrian Dyląg, Wojciech Niemczyk
{"title":"Barriers to dental treatment for patients on the autism spectrum disorder.","authors":"Magdalena Prynda, Mikołaj Mazur, Patrycja Doroz, Olga Odrzywolska, Ali Aboud, Adrian Dyląg, Wojciech Niemczyk","doi":"10.36740/WLek/207377","DOIUrl":"https://doi.org/10.36740/WLek/207377","url":null,"abstract":"<p><p>Individuals diagnosed with autism spectrum disorder (ASD) encounter significant obstacles when attempting to access dental care services. These obstacles are a result of their unique health requirements, behavioral challenges, and communication impairments. The primary challenges encompass a reliance on caregivers, challenges with adhering to proper oral hygiene practices, selective eating habits that contribute to dental caries, and an impaired capacity to communicate pain and health requirements. Furthermore, dental clinics frequently lack the capacity to accommodate individuals with ASD, exacerbating their stress during visits. A further salient issue pertains to the dearth of adequate staff training to address the needs of patients necessitating specialized care. The objective of this paper is to analyze these barriers and propose solutions that can increase the accessibility and quality of dental care for individuals with ASD, thereby improving their comfort and oral health.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 7","pages":"1433-1437"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oleksandra Yu Kushnir, Iryna M Yaremii, Kyrylo A Pantsiuk, Oleksandra O Kushnir, Kateryna M Yaremii, Kateryna V Vlasova, Olena V Vlasova
{"title":"Carbohydrate metabolism in the rats' liver under conditions of light and dark deprivation and correction by melatonin.","authors":"Oleksandra Yu Kushnir, Iryna M Yaremii, Kyrylo A Pantsiuk, Oleksandra O Kushnir, Kateryna M Yaremii, Kateryna V Vlasova, Olena V Vlasova","doi":"10.36740/WLek/205592","DOIUrl":"https://doi.org/10.36740/WLek/205592","url":null,"abstract":"<p><strong>Objective: </strong>Aim: This study aimed to investigate changes in carbohydrate metabolism in the liver of rats under light and dark deprivation and evaluate the effects of melatonin treatment.</p><p><strong>Patients and methods: </strong>Materials and Methods: Photoperiodic changes were simulated over two weeks: the natural equinox (March 16-29); the artificial equinox (12:12 light-dark cycle, 500 lux); constant light (24 hours, 500 lux) for dark deprivation; and constant dark (24 hours, 0-0.5 lux) for light deprivation. Forty-eight rats were divided into control and melatonin-treated groups (5 mg/kg daily for 14 days). Enzyme activities and glycogen content in the liver were measured using standard methods. Statistical analysis was performed using the Student's t-test.</p><p><strong>Results: </strong>Results: Glucose-6-phosphate dehydrogenase activity decreased by 18% under constant light but increased by 35% under constant dark compared to the equinox. Pyruvate kinase activity decreased by 17%, while glucose-6-phosphatase and lactate dehydrogenase activities increased by 9% and 20%, respectively, under constant light. Constant dark and melatonin treatment reduced glucose levels by 26% across all conditions, activated aerobic pathways, and increased glycogen content by 13% compared to the equinox.</p><p><strong>Conclusion: </strong>Conclusions: Melatonin treatment improved carbohydrate metabolism in the liver of rats under light and dark deprivation, suggesting its role in metabolic adaptation to altered photoperiods.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 7","pages":"1361-1366"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anastasiia Mernyk, Oleh Hyliaka, Viktoriia Sheverdina
{"title":"The right to life.","authors":"Anastasiia Mernyk, Oleh Hyliaka, Viktoriia Sheverdina","doi":"10.36740/WLek/197134","DOIUrl":"10.36740/WLek/197134","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The article is devoted to the study of the right to life as a key aspect of legal theory. The purpose of the study is to examine the theoretical aspects of the right to life, to analyze its essence, place and significance in the system of general human rights; to outline the main principles and concepts related to the right to life, to consider their evolution in different legal systems and to discuss important ethical aspects related to this topic.</p><p><strong>Patients and methods: </strong>Materials and Methods: The article examines the right to life, defines its place in the modern world, highlights the issues of correlation between this right and the right to abortion and euthanasia, and assesses the prospects for their realization. The empirical basis of the study is grounded on articles by scholars and assessments by leading experts in the field. The authors used general scientific methods, including system analysis, system modeling, and the dialectical method. To demonstrate the relationship between the right to life of an unborn child and a woman's right to abortion, a social survey was conducted among different population groups.</p><p><strong>Conclusion: </strong>Conclusions: Analyzing the right to life in the context of its interrelationship with other human rights, such as the right to liberty, the right to health and the right to a fair trial, helps to affirm the principles of the rule of law and ensure equality before the law for all. In the modern world, the concept of the right to life has become an important element of international law, which covers not only physical existence, but also the provision of a decent and quality life, health, education and social protection. Cultural and religious aspects play a significant role in shaping the understanding of the right to life. Different religious and cultural traditions have their own interpretations of the beginning and end of life, influencing attitudes to aspects related to medical interventions, abortion, euthanasia and other issues.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 1","pages":"197-209"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}