Urology Annals最新文献

{"title":"Comparison of vascular complications between external iliac and internal iliac artery anastomosis of the donor renal artery in renal transplant recipients.","authors":"G Manoj Kumar, Sunil Ashok, J Suresh Kumar","doi":"10.4103/ua.ua_59_24","DOIUrl":"10.4103/ua.ua_59_24","url":null,"abstract":"<p><strong>Introduction: </strong>The arterial anastomosis in renal transplantation is done either end-to-end to the internal iliac artery (IIA) or end-to-side to the external iliac artery (EIA). This retrospective study is to compare the vascular complications of these two techniques occurring in the immediate postoperative period.</p><p><strong>Materials and methods: </strong>The data of 111 patients who underwent renal transplantation (live and deceased) were collected from the hospital records. Fifty-four (48.6%) had live donors, and 57 (51.4%) had deceased donors. Fifty (45%) patients had anastomosis to IIA alone, 57 (51.3%) to EIA alone, and 4 (3.6%) to both vessels. Age and sex of the recipient, cause of chronic kidney disease, side of the donor kidney, and number of donor renal arteries, presence of atherosclerotic changes on the recipient's vessels, and presence of diabetes mellitus were noted. The details of the perioperative and postoperative vascular complications and the management of each one were recorded.</p><p><strong>Results: </strong>Nine patients had vascular complications, of which 5 (55.5%) patients had main vessel transplant renal artery thrombosis, 1 (11.1%) patient had accessory renal artery thrombosis, and 3 (33.3%) patients had transplant renal artery stenosis (TRAS). Out of the six cases of transplant renal artery thrombosis, 4 (66.6%) were seen in anastomosis with EIA. All 3 (100%) cases of TRAS were seen in anastomosis to the EIA. The vascular complications were not significantly associated with the type of anastomosis.</p><p><strong>Conclusion: </strong>On short-term follow-up, the incidence of vascular complications was not found to be significantly affected by the type of anastomosis.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"17 1","pages":"38-42"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of noninsulin-dependent diabetes mellitus (level of control) on sex hormone profile and erectile function.","authors":"Abdullah A Khawaji, Hossam S El-Tholoth, Muath A Albarakati, Bander A Binjabaan, Abdulaziz Alzahrani, Abdulmajeed Althobity, Abdulmalik Almardawi, Khaled Bedaiwi, Mussa AlNuami","doi":"10.4103/ua.ua_40_24","DOIUrl":"10.4103/ua.ua_40_24","url":null,"abstract":"<p><strong>Introduction: </strong>Type 2 diabetes mellitus (T2DM) is a well-established risk factor for erectile dysfunction (ED); the precise impact of glycemic control on male sexual function, including hormonal profiles, remains to be fully elucidated. This study aims to investigate the specific relationship between the degree of glycemic control in T2DM patients and the severity of both hormonal imbalances and ED.</p><p><strong>Methodology: </strong>A comparative study between two arms - relatively controlled and uncontrolled type 2 diabetic men. We considered a relatively controlled diabetes mellitus (DM), patient with glycated hemoglobin (HbA1c) of 7.9 mmol/L or less. Laboratory results for type 2 diabetic men presenting with ED were studied after stratifying them into the two groups - relatively controlled DM (HBA1c of 7.9 mmol/L or less) and uncontrolled DM (HBA1c equal to or more than 8 mmol/L). Retrieved data include patient's demographics, body mass index (BMI), hormonal profile, Complete Blood Count (CBC), lipid profile, prostate-specific antigen (PSA), urate, Vitamin D level, and the severity of ED as assessed by the International Index of Erectile Function (IIEF) scores. Statistical analysis was done to compare between the two groups using SPSS version 20. <i>P</i> < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>This study found a significant association between poor glycemic control (HbA1c ≥8%) and ED in diabetic men (<i>P</i> < 0.0001). Longer diabetes duration correlated with both ED and poor glycemic control, suggesting a potential causal link. Well-controlled diabetics had lower BMI (<i>P</i> = 0.001), higher free testosterone (FT) (<i>P</i> = 0.0002), lower sex hormone-binding globulin (SHBG) (<i>P</i> = 0.0001), and higher IIEF scores (<i>P</i> < 0.0001) compared to the poorly controlled group, indicating better erectile function and potential benefits of weight management and improved testosterone availability. While follicle-stimulating hormone and luteinizing hormone levels were not significantly affected, Vitamin D levels were higher in the well-controlled group (<i>P</i> = 0.0002), suggesting a potential role for Vitamin D in ED, although further investigation is needed. Cholesterol, low-density lipoprotein, high-density lipoprotein, triglycerides, PSA, thyroid-stimulating hormone, and T4 levels did not show significant differences but might warrant further exploration.</p><p><strong>Conclusion: </strong>This study demonstrates an association between poor glycemic control and impaired erectile function in diabetic men. Lower FT levels, elevated SHBG, and increased BMI were observed in the poorly controlled group, potentially contributing to ED. Conversely, good glycemic control correlated with improved erectile function, potentially due to higher FT availability and Vitamin D levels.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"17 1","pages":"52-57"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of prostate adenocarcinoma in transurethral resection of the prostate patients.","authors":"Yahia Ghazwani, Abdullah Alhaider, Rakan Aldharab, Faisal Aldumiaikhi, Nasser Albogami, Abdulaziz Alathel, Ali Alothman, Raghib Abusaris, Mosaad Alshahwan, Fahad Alhamad, Ziyad Aljaafri, Khalid Alduraibi","doi":"10.4103/ua.ua_53_24","DOIUrl":"10.4103/ua.ua_53_24","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to present the prevalence of incidental prostate cancer (IPCa) based on pathology reports of prostate tissue chips following transurethral resection of the prostate (TURP), as well as to assess cancer's stage, associated risk factors, and treatment modalities upon diagnosis.</p><p><strong>Methods: </strong>This cross-sectional retrospective study included patients who underwent TURP between 2015 and 2023. Patients with a preexisting PCa diagnosis were excluded, resulting in the analysis of 418 patients. Data collected encompassed basic characteristics, personal history of malignancies unrelated to IPCa, prostate volume, and prostate-specific antigen (PSA) levels. IPCa cases were identified through the pathology reports of the prostatic chips. In addition, cancer stage, Gleason score, treatment choices, and outcomes were documented for IPCa cases.</p><p><strong>Results: </strong>Among the 418 patients who underwent TURP, 35 were diagnosed with IPCa, yielding a prevalence rate of 8.4% (95% confidence interval: 5.7%-11.0%). Of these cases, 13 (37.1%) exhibited metastatic disease, and 4 (11.8%) resulted in patient mortality. IPCa patients were found to have significantly higher PSA levels and smaller prostate volumes. Multivariable logistic regression analysis indicated that elevated PSA density, ischemic heart disease, and chronic kidney disease, significantly influenced the likelihood of IPCa (<i>P</i> < 0.05). Mann-Whitney testing revealed that patients with metastatic disease had a median Gleason score of 9, whereas those with localized disease had a median score of 7 (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Our study disclosed an IPCa prevalence of 8.4%, with IPCa patients exhibiting elevated PSA levels and reduced prostate volumes, suggesting that PSA density is a valuable tool for evaluating patients with borderline PSA levels.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"17 1","pages":"43-47"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous cystolitholapaxy in reconstructed bladder through the bowel segment.","authors":"Razan Khalid Almesned, Abdulrahman Binjawhar, Waleed Altaweel, Mohammed Alomar","doi":"10.4103/ua.ua_83_24","DOIUrl":"10.4103/ua.ua_83_24","url":null,"abstract":"<p><strong>Introduction: </strong>Calculous formation is a well-known complication of lower urinary tract reconstruction using an intestinal segment. Special considerations are required as access to the reconstructed bladder is complicated. To date, a standard strategy is yet to be accepted.</p><p><strong>Objective: </strong>This study aims to investigate the efficiency and safety of percutaneous cystolitholapaxy (PCCL) access.</p><p><strong>Materials and methods: </strong>This was a retrospective analysis of patients with reconstructed lower urinary tract who developed bladder stones and were treated with PCCL.</p><p><strong>Results: </strong>Seven patients underwent a total of nine PCCLs between 2019 and 2023. Sone burden ranged from 4 to 10 cm. No intraoperative complications were faced. Three patients had residual stone fragments < 7 mm in size. Suprapubic catheter was removed between days 0 and 3 postoperative. Cystostomy was left to close spontaneously, none of the patients developed peritoneal leak after removal. Patients with Mitrofanoff channel reported no leak or compromise to the continued mechanism. Predominant stone composition was magnesium ammonium phosphate (struvite) in seven cases.</p><p><strong>Conclusion: </strong>In our experience, PCCL accessing through bowel segment without tract closure in reconstructed bladder is a reliable and safe approach. When it comes to our patient selection, no limitations to this approach have been identified.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"17 1","pages":"64-67"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of solifenacin for overactive bladder: An updated systematic review and meta-analysis.","authors":"I Gede Yogi Prema Ananda, Radika Naufal Hadi Surya, Prima Ardiansah Surya, Alfin Putratama, Dimas Panca Andhika","doi":"10.4103/ua.ua_30_24","DOIUrl":"10.4103/ua.ua_30_24","url":null,"abstract":"<p><p>Overactive bladder (OAB) is a chronic disease with the symptoms of urgency with or without incontinence. Solifenacin is an antimuscarinic drug that Excels in OAB treatment due to its specific bladder receptor targeting. While previous research had positive outcomes, reports of adverse events (AEs) highlight the need for regular updates on the safety and efficacy of solifenacin for OAB management. This study followed PRISMA 2020 guidelines and was registered to PROSPERO CRD42023445318. A comprehensive search of PubMed, ScienceDirect, and Scopus databases was conducted until July 2023. Data were analyzed using Review Manager version 5.4 (The Cochrane Collaboration, The Nordic Cochrane Centre, Copenhagen, Denmark). Solifenacin had a significantly better effect in decreasing urgency episode (mean difference (MD) = -1.09, 95% confidence interval [CI]: -1.29--0.89, <i>P</i> < 0.00001), incontinence episode (MD = -0.56, 95% CI: -0.80--0.32, <i>P</i> < 0.00001), micturition frequency (MD = -1.01, 95% CI: -1.16--0.85, <i>P</i> < 0.00001), nocturia episode (MD = -0.13, 95% CI: -0.25--0.01, <i>P</i> = 0.04), and had a higher urine volume (MD = 26.88, 95% CI: 24.17-29.59, <i>P</i> < 0.00001) per 24 h compared to placebo. Solifenacin had a significant number of AEs compared to placebo (MD = 1.75, 95% CI: 1.25-2.45, <i>P</i> = 0.001). Solifenacin significantly decreased urgency episode, incontinence episodes, micturition frequency, and nocturia episode, and had a higher urine volume per 24 h. There was a significant number of AEs in patients receiving solifenacin.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"17 1","pages":"2-8"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consumption of folk medicine in men-seeking treatment for infertility.","authors":"Abdulaziz Baazeem, Thamer Mishal M Alqurashi, Yasser Homaidi H Alharbi, Raad Abdullah D Aldahhas, Mutaz Hassan A Fatani","doi":"10.4103/ua.ua_34_24","DOIUrl":"10.4103/ua.ua_34_24","url":null,"abstract":"<p><strong>Background: </strong>Male infertility is a major health problem that can have a tremendous negative impact on the affected individuals and couples. The use of folk medicine is common practice in the Middle Eastern region, especially before seeking conventional medical treatment. Unfortunately, some of these remedies might be potentially harmful. This study aims to assess the use of folk medicine before formal medical evaluation by a male infertility specialist among men in couples with subfertility in Saudi Arabia.</p><p><strong>Materials and methods: </strong>A retrospective study of prospectively documented data was conducted among male patients who presented for evaluation of their infertility at one center in Jeddah, Saudi Arabia, from May 1, 2020, to April 30, 2021, to assess the prevalence of the use of traditional medicine among these patients.</p><p><strong>Results: </strong>The total number of patients who visited the center for infertility assessment during the specified period was of 427. Most patients had primary infertility (64.4%). Table 1 summarizes the demographic data of the patient population. About 55.3% of the patients were 40 years old or less. Patients who consumed some form of alternative medicine are 38.9%. A clinical varicocele was detected in 57.8% of these men. Patients who use alternative medicine had significantly lower semen concentration and estradiol levels (<i>P</i> = 0.02 similarly).</p><p><strong>Conclusion: </strong>About 38.9% of patients who attended our clinic were using some alternative medicine. Furthermore, patients who use alternative medicine had significantly less sperm motility and progressive motility.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"17 1","pages":"48-51"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saudi urologists' treatment pattern for high-risk <i>Bacillus</i> Calmette-Guérin naïve and <i>Bacillus</i> Calmette-Guérin unresponsive nonmuscle invasive bladder cancer.","authors":"Mohammad Alghafees, Mohamad Abou Chakra, Abdullah Alkhayal, Mohamad Moussa, Mohammad Alkhamees, Bader Alsaikhan, Ahmed Alasker, Abdulrahman Alsayyari, Abdullah Alsaghyir, Ali Alkahtani, Michael A O'Donnell","doi":"10.4103/ua.ua_43_24","DOIUrl":"10.4103/ua.ua_43_24","url":null,"abstract":"<p><strong>Objective: </strong>The objective is to learn how Saudi Arabia's urologists treat patients with <i>Bacillus</i> Calmette-Guérin (BCG)-unresponsive nonmuscle invasive bladder cancer (NMIBC) and their choices in management for BCG-naive patients during the BCG shortage.</p><p><strong>Materials and methods: </strong>A 10-min web-based survey was sent through the King Saud bin Abdul-Aziz University for Health Sciences' College of Medicine Clinical Affairs to urologists treating NMIBC based on the Saudi Urologic Association Database.</p><p><strong>Results: </strong>The questionnaire was completed by 19 urologists, most of whom (68%) were self-identified as urologic oncologists. In the 6 months before survey administration, the majority of urologists (67% of those surveyed) had treated over five NMIBC patients who had failed BCG therapy. The preferred course of treatment for these patients was a radical cystectomy, as advised by 79% of the participants. Other preferred options were intravesical chemotherapy (16%) and repeat BCG therapy (5%). Clinical trials were never chosen. Sixty percent gemcitabine (Gem), 20% mitomycin C, 10% docetaxel (Doce), and 10% sequential Gem/Doce were rated as the most preferred intravesical chemotherapy regimens used. Saudi urologists were most reluctant to utilize intravesical chemotherapy because of uncertainty about the treatment's clinical effectiveness (oncological safety) and the absence of specific guidelines from urology societies regarding the use of these drugs. BCG shortages are still a problem in Saudi Arabia, as 79% of respondents reported shortages. Most commonly, during BCG shortages, Saudi urologists rationed BCG to patients with high-risk disease, preferring pT1and/or carcinoma <i>in situ</i> to Ta high grade. The minority (16%) switch to intravesical chemotherapy in these circumstances.</p><p><strong>Conclusions: </strong>Saudi urologists have begun employing a bladder-sparing strategy, particularly intravesical chemotherapy, for BCG-unresponsive disease. To properly select treatment for this condition, there is an urgent need to implement initiatives to open clinical trials and provide guideline-based protocols to Saudi Arabia and throughout the Arab world.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"17 1","pages":"58-63"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prone versus prone-flexed position in percutaneous nephrolithotomy: A randomized controlled trial.","authors":"Diaa-Eldin Taha, Ali Ibrahim, Ahmed Zeid, Eslam Shokry, Tarek Abdelbaky, Hossam Nabeeh","doi":"10.4103/ua.ua_36_24","DOIUrl":"10.4103/ua.ua_36_24","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study intends to assess prone and flexed prone positions for percutaneous nephrolithotomy (PNL) for safety and efficacy.</p><p><strong>Methods: </strong>From May 2017 to August 2022, a stratified randomized approach was carried out to randomly assign 346 PNL candidates into prone or flexed prone groups. Perioperative data, such as stone-free rate, stay length, operative time, and complication rates, were studied.</p><p><strong>Results: </strong>In the prone and flexed prone groups, the mean ages of 51.7 ± 12.2 and 49.4 ± 11.9 min, respectively (<i>P</i> = 0.1). The mean body mass indexes of 24.2 ± 13.4 and 29.9 ± 11.9, respectively (<i>P</i> = 0.03). The pyelocaliceal perforation occurred in 15 (8%) and 11 (6.4%) participants, respectively. In the prone and flexed prone postures, postoperative bleeding occurred in 15 (7.9%) and 9 (5.4%) patients, respectively (<i>P</i> = 1.0). The average percentage decrease in hemoglobin concentration was 1.29 ± 0.42 and 1.21 ± 0.32, respectively (<i>P</i> < 0.000). The success rates were 92 and 93.6%, respectively (<i>P</i> = 0.6). The average access length was 3.9 ± 1.2 and 4.8 ± 1.8 min (<i>P</i> = 0.08), whereas the average operation duration was 68.7 ± 37.4 and 50.4 ± 21.9 min (<i>P</i> = 0.04).</p><p><strong>Conclusion: </strong>Both the prone and prone-flexed positions are equally safe for PNL. The flexed prone position is more likely to be beneficial for obese patients. The prone-flexed position enabled a somewhat shorter average operation time. The pelvicalyceal system could be more readily reached when the prone position was flexed.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"17 1","pages":"32-37"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival rate comparisons of angioembolization and neoadjuvant targeted therapy on unresectable renal cell carcinoma patients: A systematic review.","authors":"Rifqi Yanda Muhammad, Derri Hafa Nurfajri, Dahril Dahril, Jufriady Ismy","doi":"10.4103/ua.ua_114_23","DOIUrl":"10.4103/ua.ua_114_23","url":null,"abstract":"<p><strong>Objective: </strong>Renal cell cancer (RCC) is the most typical form of kidney cancer in adults, which accounts for 80% to 85% of all primary renal neoplasms. RCC develops inside the renal cortex. This study aimed to systematically review the survival rate of patients treated with targeted therapy and/or RC. Surgery is the standard therapy for RCC, even though after surgery, 20%-40% of patients with localized RCC would experience distant metastases. Metastases or large RCC are not amenable to surgery. Unresectable RCC can be treated palliatively with angioembolization or neoadjuvant therapy. This study aims to review the survival rate comparisons of angioembolization and neoadjuvant targeted therapy on unresectable renal cell carcinoma.</p><p><strong>Methods: </strong>A thorough search across databases such as PubMed, Cochrane Library, and ProQuest was conducted for articles published from 2018 to 2023. To uphold research integrity, duplicates, reviews, and incomplete articles were excluded, ensuring only pertinent and original research findings for subsequent analysis.</p><p><strong>Results: </strong>Database search yielded 247 articles, which were systematically eliminated, leaving 6 relevant articles. Analyzed articles showed the overall survival of patients treated with angioembolization and neoadjuvant agents.</p><p><strong>Conclusion: </strong>Unresectable RCC can be treated palliatively with angioembolization. Angioembolization may improve clinical effectiveness and lessen side effects by boosting local concentrations of drugs. Drug-eluting bead transarterial chemoembolization is a novel embolization option that can embolize the arteries that feed the tumor and cutoff the blood supply to the tumor. Sunitinib, the most studied medicinal agent, was found to have higher effectiveness when combined with angioembolization.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"251-260"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of laparoscopic sacrocolpopexy using self-cut mesh on pelvic organ prolapse.","authors":"Alfa Putri Meutia, Suskhan Djusad, Tyas Priyatini, Kevin Yonathan, Tokumasa Hayashi, Jimmy Nomura","doi":"10.4103/ua.ua_142_21","DOIUrl":"10.4103/ua.ua_142_21","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of the study was to investigate the long-term outcome and complication rate of laparoscopic sacrocolpopexy (LSC) using self-cut mesh as pelvic organ prolapse treatment.</p><p><strong>Methods: </strong>A retrospective cohort study on patients undergoing LSC was done at Kameda Medical Center from January 2013 to January 2018. Data for this study were taken from all women with pelvic organ prolapse who had undergone LSC using self-cut polypropylene mesh. Patients with a previous history of hysterectomy were excluded from the study. An evaluation was done preoperatively, on 6-month and 1-year postoperative follow-up period using Pelvic Organ Prolapse Quantification (POP-Q) and The International Consultation on Incontinence Questionnaire-short form (ICIQ-SF) questionnaire.</p><p><strong>Results: </strong>There were 702 subjects who met the inclusion and exclusion criteria. The clinical characteristics of the subjects were recorded. The scores during admission, 6 months and 1 year postoperative are: POP Q scores: 6.50 ± 5.69 vs. 5.11 ± 4.85 vs. 4.78 ± 4.31, <i>P</i> = 0.049 and ICIQ SF scores: 2.92 ± 0.62 vs. 1.10 ± 0.36 vs. 1.13 ± 0.41, <i>P</i> < 0.001). A total of 17 (2.4%) perioperative and postoperative complications were observed on subjects.</p><p><strong>Conclusion: </strong>LSC using self-cut mesh could produce satisfactory results in pelvic organ prolapse patients on 6-month and 1-year follow-up period with minimal perioperative complications.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"284-287"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}