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Survival rate comparisons of angioembolization and neoadjuvant targeted therapy on unresectable renal cell carcinoma patients: A systematic review. 血管栓塞术与新辅助靶向疗法对不可切除肾细胞癌患者生存率的比较:系统综述。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_114_23
Rifqi Yanda Muhammad, Derri Hafa Nurfajri, Dahril Dahril, Jufriady Ismy
{"title":"Survival rate comparisons of angioembolization and neoadjuvant targeted therapy on unresectable renal cell carcinoma patients: A systematic review.","authors":"Rifqi Yanda Muhammad, Derri Hafa Nurfajri, Dahril Dahril, Jufriady Ismy","doi":"10.4103/ua.ua_114_23","DOIUrl":"10.4103/ua.ua_114_23","url":null,"abstract":"<p><strong>Objective: </strong>Renal cell cancer (RCC) is the most typical form of kidney cancer in adults, which accounts for 80% to 85% of all primary renal neoplasms. RCC develops inside the renal cortex. This study aimed to systematically review the survival rate of patients treated with targeted therapy and/or RC. Surgery is the standard therapy for RCC, even though after surgery, 20%-40% of patients with localized RCC would experience distant metastases. Metastases or large RCC are not amenable to surgery. Unresectable RCC can be treated palliatively with angioembolization or neoadjuvant therapy. This study aims to review the survival rate comparisons of angioembolization and neoadjuvant targeted therapy on unresectable renal cell carcinoma.</p><p><strong>Methods: </strong>A thorough search across databases such as PubMed, Cochrane Library, and ProQuest was conducted for articles published from 2018 to 2023. To uphold research integrity, duplicates, reviews, and incomplete articles were excluded, ensuring only pertinent and original research findings for subsequent analysis.</p><p><strong>Results: </strong>Database search yielded 247 articles, which were systematically eliminated, leaving 6 relevant articles. Analyzed articles showed the overall survival of patients treated with angioembolization and neoadjuvant agents.</p><p><strong>Conclusion: </strong>Unresectable RCC can be treated palliatively with angioembolization. Angioembolization may improve clinical effectiveness and lessen side effects by boosting local concentrations of drugs. Drug-eluting bead transarterial chemoembolization is a novel embolization option that can embolize the arteries that feed the tumor and cutoff the blood supply to the tumor. Sunitinib, the most studied medicinal agent, was found to have higher effectiveness when combined with angioembolization.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"251-260"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of laparoscopic sacrocolpopexy using self-cut mesh on pelvic organ prolapse. 使用自切网片的腹腔镜骶骨整形术对盆腔脏器脱垂的疗效。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_142_21
Alfa Putri Meutia, Suskhan Djusad, Tyas Priyatini, Kevin Yonathan, Tokumasa Hayashi, Jimmy Nomura
{"title":"Outcomes of laparoscopic sacrocolpopexy using self-cut mesh on pelvic organ prolapse.","authors":"Alfa Putri Meutia, Suskhan Djusad, Tyas Priyatini, Kevin Yonathan, Tokumasa Hayashi, Jimmy Nomura","doi":"10.4103/ua.ua_142_21","DOIUrl":"10.4103/ua.ua_142_21","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of the study was to investigate the long-term outcome and complication rate of laparoscopic sacrocolpopexy (LSC) using self-cut mesh as pelvic organ prolapse treatment.</p><p><strong>Methods: </strong>A retrospective cohort study on patients undergoing LSC was done at Kameda Medical Center from January 2013 to January 2018. Data for this study were taken from all women with pelvic organ prolapse who had undergone LSC using self-cut polypropylene mesh. Patients with a previous history of hysterectomy were excluded from the study. An evaluation was done preoperatively, on 6-month and 1-year postoperative follow-up period using Pelvic Organ Prolapse Quantification (POP-Q) and The International Consultation on Incontinence Questionnaire-short form (ICIQ-SF) questionnaire.</p><p><strong>Results: </strong>There were 702 subjects who met the inclusion and exclusion criteria. The clinical characteristics of the subjects were recorded. The scores during admission, 6 months and 1 year postoperative are: POP Q scores: 6.50 ± 5.69 vs. 5.11 ± 4.85 vs. 4.78 ± 4.31, <i>P</i> = 0.049 and ICIQ SF scores: 2.92 ± 0.62 vs. 1.10 ± 0.36 vs. 1.13 ± 0.41, <i>P</i> < 0.001). A total of 17 (2.4%) perioperative and postoperative complications were observed on subjects.</p><p><strong>Conclusion: </strong>LSC using self-cut mesh could produce satisfactory results in pelvic organ prolapse patients on 6-month and 1-year follow-up period with minimal perioperative complications.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"284-287"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does tilt-retrograde intrarenal surgery enhance stone clearance and offer better surgical ergonomics in patients with renal calculi? A prospective randomized control study. 倾斜逆行肾内手术能否提高结石清除率,并为肾结石患者提供更好的手术工效?一项前瞻性随机对照研究。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_44_24
Arvind Ramachandran, Vivek Meyyappan, Hariharasudhan Sekar, Gayathri Thiruvengadam, Sriram Krishnamoorthy
{"title":"Does tilt-retrograde intrarenal surgery enhance stone clearance and offer better surgical ergonomics in patients with renal calculi? A prospective randomized control study.","authors":"Arvind Ramachandran, Vivek Meyyappan, Hariharasudhan Sekar, Gayathri Thiruvengadam, Sriram Krishnamoorthy","doi":"10.4103/ua.ua_44_24","DOIUrl":"10.4103/ua.ua_44_24","url":null,"abstract":"<p><strong>Introduction: </strong>Retrograde intrarenal surgery (RIRS) is the standard treatment for renal calculi. Direct visualization and fragmentation are its major advantages. The variable stone clearance rates and the ergonomic challenges faced by urologists are a few limitations. Table tilt enhances stone clearance and improves surgical ergonomics by facilitating better access to stones and reducing procedural strain.</p><p><strong>Subjects and methods: </strong>In this prospective study, patients with intrarenal calculi were randomized into standard lithotomy RIRS (S-RIRS) and table-tilted RIRS (T-RIRS) groups. Specified table tilts were suggested for each of the stone locations. The outcomes with regard to stone clearance, operative and lasing time, and ergonomics were studied.</p><p><strong>Results: </strong>About 100 patients were studied, with 50 in each group. The overall operating time and lasing time in the T-RIRS group were less than that in the S-RIRS group (<i>P</i> < 0.001). The complication rates were the same in both groups. Most surgeons felt that the surgical ergonomics was better in the T-RIRS group (<i>P</i> < 0.001). When stone-free status was analyzed, seven patients in the S-RIRS group and one in the T-RIRS group had residual stones. The mean Borg category-ratio 10 (CR-10) scores in the S-RIRS and T-RIRS groups were 4.18 and 2.20, respectively (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>This is the first study to document the distinct advantages of T-RIRS and its benefits on surgical ergonomics. T-RIRS resulted in significantly shorter operative and lasing times, particularly for stones in lower calyces. Surgical ergonomics, assessed by the Borg CR-10 scale, were significantly better in the T-RIRS group. T-RIRS should become a standard of care for patients undergoing RIRS.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"306-314"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rationale of restaging transurethral resection of bladder tumor in patients with nonmuscle invasive bladder cancer in the current era. 非肌层浸润性膀胱癌患者经尿道膀胱肿瘤切除术重新分期的理论依据。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_50_24
Amit Sharma, R T Raghavendra, Deepak Biswal, Pradhuman Yadav, Saryu Goel, Satyadeo Sharma
{"title":"Rationale of restaging transurethral resection of bladder tumor in patients with nonmuscle invasive bladder cancer in the current era.","authors":"Amit Sharma, R T Raghavendra, Deepak Biswal, Pradhuman Yadav, Saryu Goel, Satyadeo Sharma","doi":"10.4103/ua.ua_50_24","DOIUrl":"10.4103/ua.ua_50_24","url":null,"abstract":"<p><strong>Background: </strong>We present retrospective data of patients with nonmuscle invasive bladder cancer (NMIBC) who underwent restaging transurethral resection of bladder tumor (Re-TURBT) at a tertiary care center.</p><p><strong>Materials and methods: </strong>Records of all NMIBC patients undergoing Re-TURBT between March 2021 and September 2023 were retrospectively analyzed. Patients were risk stratified based on TURBT pathology. Re-TURBT was performed between 4 and 6 weeks. Adverse features such as number, size, and appearance were noted. Patients with persistent disease at Re-TURBT were counseled for early cystectomy with urinary diversion or intravesical Bacillus Calmette-Guerin (BCG). In case of disease upstaging, patients were counseled for radical cystectomy.</p><p><strong>Results: </strong>Thirty-eight NMIBC patients (30 males and 8 females) underwent Re-TURBT. Six patients had residual/persistent disease at 6 weeks, all high risk and high grade (HG, <i>P</i> value not significant, <i>P</i> = 0.31). There was no association with number and appearance of tumors with residual/persistence at 6 weeks. The mean lesion size on imaging in cases with and without residual disease was 3.32 ± 0.86 versus 3.39 ± 0.92 cm, respectively, <i>P</i> value not significant (0.868). There was no residual disease in the low-grade (LG) pT1 group, but HG pTa and pT1 (<i>n</i> = 3) had residual disease. Four HG pT1 patients opted for early cystectomy. Two patients each had pT0 and two pT2. At 3 months of follow-up, urethral strictures were seen both in high risk and intermediate risk. Among four patients who had stricture, meatal stenosis was common (50%, <i>n</i> = 2). Two patients had long-segment stricture requiring perineal urethrostomy with stage I Johannsen repair. All HG pT1 lesion patients eventually underwent cystectomy (3 were under staged and two treated completely with TURBT, one with TURBT + BCG and one patient progressed to metastasis).</p><p><strong>Conclusion: </strong>Re-TURBT is essential for the management of HG pTa and HG pT1 lesions for accurate staging and treatment of residual disease. However, LG pT1 patients can safely be excluded from Re-TURBT.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"288-291"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility, efficacy, and safety of retrograde intrarenal surgery in <1-year age group: A single-center experience. 1 岁以下儿童逆行肾内手术的可行性、有效性和安全性:单中心经验。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_119_23
Chandra Mohan Vaddi, Hemnath Anandan, Paidakula Ramakrishna, P M Siddalinga Swamy, Soundarya Ganesan, Rakesh Panda
{"title":"Feasibility, efficacy, and safety of retrograde intrarenal surgery in <1-year age group: A single-center experience.","authors":"Chandra Mohan Vaddi, Hemnath Anandan, Paidakula Ramakrishna, P M Siddalinga Swamy, Soundarya Ganesan, Rakesh Panda","doi":"10.4103/ua.ua_119_23","DOIUrl":"10.4103/ua.ua_119_23","url":null,"abstract":"<p><strong>Purpose: </strong>Urolithiasis in infants is uncommon. Percutaneous nephrolithotomy, extracorporeal shockwave lithotripsy, and retrograde intrarenal surgery (RIRS) are the management options. RIRS is the least studied of these options in infants. In our series of 23 cases, we aim to assess the feasibility, efficacy, and safety of RIRS in <1-year age group.</p><p><strong>Materials and methods: </strong>This was a retrospective analysis of a series of 23 infants who underwent RIRS in our hospital from January 2018 to March 2021. Children who were <12 months of age and had the largest stone size of <20 mm were included in the study.</p><p><strong>Results: </strong>Twenty-three patients (male - 15; female - 8) were included in the study. The mean age was 10 ± 2.31 months (range, 4-12 months). The mean stone size was 11.6 ± 2.96 mm (range, 7.5-19 mm). The mean operative time was 29.44 ± 7.45 min (range, 17-42 min). Six patients (22.2%) had mild hematuria (Clavien I), and seven patients (25.9%) had postoperative fever. Stone size had a significant positive correlation with laser time, operative time, and intraoperative intravasation, but no significant association with stone-free rate. At 2-month follow-up, 4 (three patients) out of 27 renal units had residual stones (stone-free rate [SFR] - 85.1%). No patient had long-term complications like urethral or ureteric stricture or stone recurrence during the given follow-up period.</p><p><strong>Conclusion: </strong>RIRS is a feasible and minimally invasive treatment for renal stones in infants with acceptable SFRs.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"270-276"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Our experience of laparoscopic vesicovaginal fistula repair in a tertiary care center. 我们在一家三级医疗中心进行腹腔镜膀胱阴道瘘修补术的经验。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_65_23
Ahsan Ahmad, Khalid Mahmood, Nikhil Ranjan, Md Zaid Imbisat, Rajesh Kumar Tiwari
{"title":"Our experience of laparoscopic vesicovaginal fistula repair in a tertiary care center.","authors":"Ahsan Ahmad, Khalid Mahmood, Nikhil Ranjan, Md Zaid Imbisat, Rajesh Kumar Tiwari","doi":"10.4103/ua.ua_65_23","DOIUrl":"10.4103/ua.ua_65_23","url":null,"abstract":"<p><strong>Objective: </strong>Laparoscopic repair of vesicovaginal fistula (VVF) is gaining popularity day by day, but we have limited literature on it. This study is to evaluate the safety, feasibility, and outcomes of laparoscopic VVF repair in a tertiary care center in Eastern India.</p><p><strong>Subjects and methods: </strong>This study is a single-center retrospective study in which 11 patients of supratrigonal VVF were evaluated who underwent laparoscopic repair. Preoperative workup included history, examination, computed tomography urography, cystoscopy, and vaginoscopy. After informed consent, laparoscopic VVF repair was done under general anesthesia. Duration of surgery, the need for conversion to open procedure, intraoperative bowel injury, the need for postoperative blood transfusion, postoperative hospital stay, postoperative urinary leak, and any incontinence after catheter removal were noted.</p><p><strong>Results: </strong>All the patients had primary supratrigonal fistula of approximate size in the range of 1.5-2.0 cm. All the included patients were operated on successfully by laparoscopic technique with a mean duration of surgery of 177.91 ± 6.14 min. The mean duration of postoperative hospital stay was 4.45 ± 0.52 days. There was no incidence of postoperative urine leak in any patient. After urethral catheter removal, all the patients voided well without any incontinence.</p><p><strong>Conclusions: </strong>Laparoscopic VVF repair is a safe and feasible option with satisfactory intraoperative and postoperative outcomes.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"266-269"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive preoperative cultures but not bacterial species predict postoperative urine culture results after holmium laser enucleation of the prostate. 钬激光前列腺去核术后尿液培养结果的预测因素是术前培养阳性而非细菌种类。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_31_24
Karen M Doersch, Timothy D Campbell, Ashley Li, Rajat K Jain, Scott O Quarrier
{"title":"Positive preoperative cultures but not bacterial species predict postoperative urine culture results after holmium laser enucleation of the prostate.","authors":"Karen M Doersch, Timothy D Campbell, Ashley Li, Rajat K Jain, Scott O Quarrier","doi":"10.4103/ua.ua_31_24","DOIUrl":"10.4103/ua.ua_31_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate risk factors associated with positive urine cultures following holmium laser enucleation of the prostate (HoLEP).</p><p><strong>Materials and methods: </strong>The data from a prospectively maintained database were analyzed to evaluate urine culture results following HoLEP and determine the contribution of predefined variables (age, prostate size, Charlson comorbidity score, surgical time [surrogate for case difficulty], the presence of a catheter preoperatively, postoperative urinary retention, and preoperative positive culture) on urine culture positivity at 60 days postoperatively. Statistical analyses included logistic regression and ANOVA.</p><p><strong>Results: </strong>The data from 136 subjects were included in the database and were evaluated at a median of 13.37 ± 6.72 months after their HoLEP. Postoperative positive cultures were noted in 23 subjects (16.91%). Preoperative positive cultures were found to predict positive postoperative urine cultures (odds ratio: 3.78, confidence interval: 1.18-12.78, <i>P</i> = 0.03). However, the preoperative and postoperative results were discordant in 9 of 14 subjects with both positive preoperative and postoperative cultures.</p><p><strong>Conclusions: </strong>Positive preoperative cultures were predictive of positive postoperative cultures. However, the pre- and postoperative results were often discordant. Host factors increasing susceptibility to bacteriuria may explain these findings.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"292-295"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal cell carcinoma with inferior vena cava thrombus: Survival and prognostic factors in surgically treated patients. 伴有下腔静脉血栓的肾细胞癌:手术治疗患者的存活率和预后因素。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_113_23
Miguel Miranda, Joana Polido, Miguel Fernandes, Filipe Lopes, Tiago Oliveira, Tomé Lopes, Luís Costa, Ângelo Nobre, Tito Palmela Leitão, Luís Mendes Pedro, José Palma Dos Reis
{"title":"Renal cell carcinoma with inferior vena cava thrombus: Survival and prognostic factors in surgically treated patients.","authors":"Miguel Miranda, Joana Polido, Miguel Fernandes, Filipe Lopes, Tiago Oliveira, Tomé Lopes, Luís Costa, Ângelo Nobre, Tito Palmela Leitão, Luís Mendes Pedro, José Palma Dos Reis","doi":"10.4103/ua.ua_113_23","DOIUrl":"10.4103/ua.ua_113_23","url":null,"abstract":"<p><strong>Introduction: </strong>Renal cell carcinoma (RCC) often develops a tumor thrombus extending into the inferior vena cava (IVC). Radical nephrectomy with IVC thrombectomy is the standard treatment, although prognostic factors are yet to be properly established.</p><p><strong>Objectives: </strong>The objectives of this study were to review the clinicopathological features of surgically treated patients with RCC and IVC thrombus and to investigate potential prognostic factors.</p><p><strong>Materials and methods: </strong>This retrospective analysis covered patients with RCC and IVC thrombus who underwent surgical treatment at a tertiary center over 12 years.</p><p><strong>Results: </strong>Of the 32 patients included, 56% and 41% had nodal (N1) and metastatic (M1) diseases, respectively. Thrombus level was 1 in 25% and 4 in 21.9% of cases, according to the Mayo classification. The median follow-up was 17.0 months. The median overall survival (OS) was 20.0 months, with a median OS of 36.0 months in M0 patients and 10.0 months in M1 patients (log-rank <i>P</i> = 0.029). Stage IV disease (T4 and/or M1 status) (hazard ratio [HR]: 2.85, <i>P</i> = 0.021), fat invasion (HR: 2.52, <i>P</i> = 0.044), positive margins (HR: 2.54, <i>P</i> = 0.037), American Society of Anesthesiologists score (HR: 2.59, <i>P</i> = 0.033), tumor size >100 mm (HR: 2.538, <i>P</i> = 0.033), and higher neutrophil-to-lymphocyte ratio (<i>r</i> <sup>2</sup> = 0.304, <i>P</i> = 0.001) were significantly associated with worse OS in univariate analysis. Thrombus level did not impact prognosis.</p><p><strong>Conclusions: </strong>Certain clinicopathological factors, but not thrombus level, appear to influence prognosis. Prospective multicentric randomized studies are needed to better stratify patient risk, improve prognostic prediction, and evaluate systemic therapy responses.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"277-283"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors and potential risk factors of iatrogenic ureteral injury following common obstetric and gynecological surgeries: A single-center retrospective study. 常见妇产科手术后输尿管先天性损伤的预测因素和潜在风险因素:单中心回顾性研究。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_25_24
Yahya Ghazwani, Nasser Albogami, Mohammed Aldwaighri, Ghassan Alhajress, Abdullah Alsaghyir, Faisal Balaraj
{"title":"Predictors and potential risk factors of iatrogenic ureteral injury following common obstetric and gynecological surgeries: A single-center retrospective study.","authors":"Yahya Ghazwani, Nasser Albogami, Mohammed Aldwaighri, Ghassan Alhajress, Abdullah Alsaghyir, Faisal Balaraj","doi":"10.4103/ua.ua_25_24","DOIUrl":"10.4103/ua.ua_25_24","url":null,"abstract":"<p><strong>Objectives: </strong>As iatrogenic ureteral injury carries a high burden and is associated with increased postoperative morbidity and mortality, the purpose of this study is to determine the incidence and potential risk factors of iatrogenic ureteral injury following common obstetric and gynecological surgeries in King Abdulaziz Medical City.</p><p><strong>Methods: </strong>This was a single-center retrospective cohort study based on data extracted from an electronic hospital information system conducted in King Abdulaziz Medical City, Riyadh, Saudi Arabia. Three thousand four hundred and sixty-four cases of cesarean section (C-section) and hysterectomy from January 1, 2021, to December 31, 2022, were reviewed. All cases of C-section and hysterectomy in which the urology department was consulted for suspected iatrogenic ureteric injuries were included in the study. All cases other than C-sections and hysterectomy in which the urology department was consulted for suspected iatrogenic ureteric injuries were excluded from the study.</p><p><strong>Results: </strong>A total of 45 patients for whom urology was consulted for suspected ureteral injury were included in this study. Approximately (35.6%) one-third of the patients had positive findings of ureteral injury following common obstetric and gynecological surgeries. About 41.2% of these patients had previous gynecological surgeries. Other potential risk factors were tested such as age and body mass index. Older patients were slightly at higher risk of iatrogenic ureteral injury (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Ureteral injury in obstetric and gynecological surgeries is rare yet serious complication. The findings of this study suggest that the incidence of iatrogenic ureteral injury was relatively associated with older age.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"296-300"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of urolithiasis in Saudi Arabia: A systematic literature review. 沙特阿拉伯的尿路结石发病率:系统文献综述。
IF 0.7
Urology Annals Pub Date : 2024-10-01 Epub Date: 2024-10-16 DOI: 10.4103/ua.ua_29_24
Bandar A Alhubaishy, Omar A Bokhary, Majed A Alhuzali, Hanaa A Bokhary
{"title":"Prevalence of urolithiasis in Saudi Arabia: A systematic literature review.","authors":"Bandar A Alhubaishy, Omar A Bokhary, Majed A Alhuzali, Hanaa A Bokhary","doi":"10.4103/ua.ua_29_24","DOIUrl":"10.4103/ua.ua_29_24","url":null,"abstract":"<p><p>Urolithiasis is a common urological disease that can have a negative impact on health and quality of life in people worldwide. Multiple studies have investigated the prevalence of urolithiasis worldwide. However, research on this disease in Saudi Arabia is very limited. This review was conducted to investigate the prevalence of urolithiasis and its associations in Saudi Arabia. A standardized, systematic search strategy was conducted to identify observational studies that reported the prevalence of urolithiasis in Saudi Arabia. The search included published studies between January 2000 and October 2023. A variation in prevalence between regions was found and was reported to range from 6% to 19%. A significant association between urolithiasis and two factors, increasing age and family history, was found. Studies on urolithiasis are limited in Saudi Arabia. Despite this, it is evident that the prevalence of urolithiasis is comparable in other parts of the world. Public awareness and lifestyle modification efforts may help reduce this disease's impact on our population.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"16 4","pages":"261-265"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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