Type II diabetes miletus: Does it increase the chance to fail the first trail of void following transurethral resection of prostate (TURP)?

Background: Transurethral resection of the prostate (TURP) remains the gold standard surgical approach for benign prostatic obstruction. Our aim in this study was to assess factors affecting failure of the first trial of void (TOV) post-TURP.

Methods: This was a retrospective study that included all patients who underwent TURP from January 2016 to January 2020 at our tertiary care endourology center. Patients and prostate characteristics were collected. Patients who developed complications intraoperatively were excluded. Multivariable analysis was performed to identify factors which predict the failure of the first TOV. Furthermore, predictors of acute urinary retention within 30 days from TURP were assessed.

Results: A total of 263 patients who underwent TURP were collected. The mean age was 72.76 ± 8.65 years. Patients with diabetes mellitus (DM) were 50.2% and hypertension were 64.6%. The majority of patients, 78%, had a history of retention before TURP and the most commonly used medication before the operation was alpha-blocker. On univariate analysis, patients who were on Foley's catheter and patients who had type II DM were associated with significantly higher failure of first TOV (15.2% vs. 5.9%; P = 0.031) and (18.2% vs. 6.1%; P = 0.003). However, the multivariable analysis revealed that only patients with type II DM had six times (odds ratios: 5.837; P = 0.006) higher chance to fail the first TOV.

Conclusion: Type II DM was associated with six times increase in the incidence of failure of the first TOV following TURP.