Urology Annals最新文献

{"title":"Use of autologous platelet-rich plasma in short-segment urethral stricture (a comparative study): Experience in a tertiary care hospital.","authors":"Sunirmal Choudhury, Biplabendu Talukder, Soumen Saha, Vipin Katiyar","doi":"10.4103/ua.ua_110_25","DOIUrl":"https://doi.org/10.4103/ua.ua_110_25","url":null,"abstract":"<p><strong>Background: </strong>Optical internal urethrotomy (OIU) remains a common intervention for short-segment urethral stricture, but recurrence rates remain high. Platelet-rich plasma (PRP), rich in bioactive growth factors, may enhance wound healing and reduce fibrosis. This study evaluates the impact of submucosal autologous PRP injection as an adjunct to OIU.</p><p><strong>Methodology: </strong>In this prospective comparative study, 64 patients with short-segment urethral stricture (<2 cm) were randomized into two equal groups: OIU alone (control) and OIU with submucosal PRP injection (PRP group). Four milliliters of autologous PRP were injected at eight submucosal sites after urethrotomy. Primary outcome was postoperative maximum flow rate (ml/min) (Qmax) at 6 months. Nonparametric statistics (Mann-Whitney U-test) were used.</p><p><strong>Results: </strong>Baseline demographics and preoperative flow parameters were comparable between groups (<i>P</i> > 0.05). At 6 months, mean Qmax improved from 6.39 to 17.34 mL/s in the PRP group and from 5.93 to 11.39 mL/s in the control group (<i>P</i> < 0.001). Median Qmax was 17 vs. 12 mL/s, respectively. Mann-Whitney analysis demonstrated a significant difference (U = 123, <i>P</i> < 0.001; effect size <i>r</i> ≈ 0.53). No major complications were observed.</p><p><strong>Conclusion: </strong>Submucosal PRP injection significantly enhances postoperative urinary flow following OIU. Its regenerative and antifibrotic properties suggest a promising role as an adjunct therapy. Larger trials with long-term follow-up are needed to determine durability of benefit and recurrence outcomes.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 2","pages":"111-117"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"True freehand transperineal prostate biopsy under local anesthesia: A prospective study for efficacy, safety, and tolerability in a tertiary care hospital.","authors":"Amitayu Jana, Debansu Sarkar","doi":"10.4103/ua.ua_119_25","DOIUrl":"https://doi.org/10.4103/ua.ua_119_25","url":null,"abstract":"<p><strong>Introduction: </strong>Prostate cancer remains a major cause of cancer mortality worldwide, with a rising incidence in Asia. Transrectal biopsy, though standard, carries the risks of infection, sepsis, and readmission. Transperineal (TP) biopsy under local anesthesia (LA) offers better safety. While grid-based and device-assisted methods are well established, a true freehand technique may be a cost-effective alternative in resource-limited settings.</p><p><strong>Materials and methods: </strong>In this prospective observational study (February 2023-January 2025), patients with elevated prostate-specific antigen (PSA), abnormal digital rectal examination, or Prostate Imaging Reporting and Data System (PI-RADS) ≥3 underwent TP biopsy using a true freehand technique under transrectal ultrasound guidance. Outcomes included pain (VAS), complications, and cancer detection rate.</p><p><strong>Statistical analysis: </strong>SPSS 26.0 software was used for analysis. The Chi-square and Friedman tests were applied. Multivariate regression was performed to determine odds ratios (ORs). <i>P</i> ≤ 0.05 was considered statistically significant.</p><p><strong>Results: </strong>One hundred and ten patients were biopsied (mean age: 66.2 ± 7.1 years; PSA 13.73 ± 7.68 ng/mL). PI-RADS 3, 4, and 5 lesions were found in 38.2%, 30.9%, and 30.9%, respectively. Most of the patients reported mild pain (VAS: ≤3), mainly during sampling. Minor complications included hematuria (25.4%), urinary retention (10%), and perineal hematoma (0.9%). No sepsis, readmissions, or Clavien-Dindo ≥ III events occurred. Clinically significant cancer was diagnosed in 61 (55.5%) patients. Gleason 4 + 5 was seen in 24 cases (39.9%). PI-RADS 4 (OR = 4.84) and 5 (OR = 6.64) were strongly associated with malignancy (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>True freehand TP prostate biopsy under LA is safe, well-tolerated, and diagnostically effective. It is a viable alternative to device-assisted methods, especially in resource-limited settings.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 2","pages":"162-170"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new modification of renal track creation in percutaneous nephrolithotomy (PCNL), a novel technique.","authors":"Mohamed Abdelrahman Alhefnawy, Mohamed Abdelzaher, Helmy Ahmed Eldib, Mohamed Kadry, Mahmoud Mobarak","doi":"10.4103/ua.ua_37_25","DOIUrl":"10.4103/ua.ua_37_25","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of the study is to compare our novel access creation technique and standard percutaneous nephrolithotomy (PCNL) in terms of perioperative outcomes.</p><p><strong>Patients and methods: </strong>Sixty patients with partial or complete stag horn stones that were larger than 4 cm were the subjects of the prospective randomized clinical trial. Randomly, the patients were divided into two equal groups; group 1 (the novel group) was administered the novel technique. Using single-step Amplatz dilatation followed by the use of a modified laparoscope trocar 36 Fr as an access sheath with a side screw for suction and group 2 (control group) underwent standard PCNL. The preoperative evaluation of all patients included a comprehensive clinical evaluation, a normal X-ray of the kidney-ureter-bladder, and a computed tomography scan of the abdomen without contrast, and laboratory investigations. Data regarding the perioperative period were documented.</p><p><strong>Results: </strong>A significant difference was observed in the operative and puncture times between both groups, with Group 1 (the novel group) demonstrating shorter operative and puncture times than those of Group 2 (control group) (<i>P</i> = 0.001, 0.001). Group 1 (novel group) exhibited significantly reduced need for opioids for pain (<i>P</i> = 0.028), levels of bleeding necessitating blood transfusion, and residual fragments than group 2 (control group) (<i>P</i> < 0.05). Group 1 (novel group) experienced a significantly shorter hospital stay than Group 2 (control group) (<i>P</i> = 0.001).</p><p><strong>Conclusions: </strong>We have developed a novel method for the safe and effective construction of PCNL tracks in the presence of large renal stones. The novel technique, when compared to the standard PCNL, had shorter operative time, puncture time, hospital stay, and less postoperative complications, with a higher satisfaction rate.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 1","pages":"75-82"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of patch cystoplasty in intractable interstitial cystitis/bladder pain syndrome.","authors":"Nagendra Nath Mishra","doi":"10.4103/ua.ua_67_24","DOIUrl":"10.4103/ua.ua_67_24","url":null,"abstract":"<p><strong>Purpose: </strong>Management of intractable interstitial cystitis/bladder pain syndrome (IC/BPS) is very challenging with no standard treatment. Reconstructive surgery is one of the options. Here, we present our long-term experience of treating intractable IC/BPS with patch/clam ileocystoplasty.</p><p><strong>Patients and methods: </strong>From September 2012, 19 patients diagnosed with IC/BPS underwent patch cystoplasty. Two patients died, so data from 17 patients was analyzed. 15-20 cm segment of the ileum was isolated, leaving distal most 15 cm of ileum from the ileocecal junction intact. The urinary bladder was opened judiciously in the sagittal section, incising anteriorly from the bladder neck to trigone posteriorly. The patch of the ileum was opened at the antimesenteric border and interposed between the two halves of the bladder. Two suprapubic catheters were placed through the bladder segment. No urethral catheter was placed. A global response assessment questionnaire, 10-point pain scale, interstitial cystitis symptom index, and interstitial cystitis problem index were used to evaluate the response to treatment.</p><p><strong>Results: </strong>The average age of the patients included was 47 years, 11 females and 6 males. The average follow-up was of 3.9 years, and the median was 3 years. All 17 patients improved, 13 showed marked improvement and 4 moderate improvement. 11 patients had Hunners Lesion, 14 patients are voiding naturally and 3 are on self-catheterization.</p><p><strong>Conclusions: </strong>For IC/BPS, surgery should be offered as the last treatment option in cases of intractable disease. In our series, Patch cystoplasty has shown favorable results with satisfactory outcomes and minimum morbidity, and better quality of life even on long-term follow-up.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 1","pages":"25-32"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of <i>en bloc</i> versus three-lobe enucleation technique for the management of benign prostatic obstruction: A systematic review and meta-analysis.","authors":"Andika Afriansyah, Kiwah Andanni Bangsawan, Moammar Andar Roemare Siregar, Sung Yong Cho, Nugroho Purnomo, Doddy Widyawan Hami Seno, Hendy Mirza","doi":"10.4103/ua.ua_85_25","DOIUrl":"10.4103/ua.ua_85_25","url":null,"abstract":"<p><p>Benign prostatic obstruction (BPO) is a common condition in aging men that often requires surgical intervention when medical therapy fails. Anatomical Endoscopic Enucleation of the Prostate (AEEP) has become an established minimally invasive treatment, with <i>en bloc</i> and three-lobe techniques being the most commonly used approaches. This systematic review and meta-analysis aimed to compare perioperative outcomes, surgical efficiency, and postoperative recovery between <i>en bloc</i> and three-lobe enucleation techniques. A comprehensive literature search was conducted in PubMed, Wiley Online Library, Scopus, Embase, SpringerLink, and the Cochrane Library for studies published up to May 2024. Eligible studies directly compared <i>en bloc</i> and three-lobe enucleation techniques and reported relevant perioperative and postoperative outcomes. Data were analyzed in accordance with PRISMA guidelines, and the risk of bias was assessed using the ROBINS-I tool. Six retrospective observational studies involving a total of 1,765 patients were included. <i>En bloc</i> enucleation was associated with a significantly shorter enucleation time compared with the three-lobe technique. No significant differences were observed in enucleation efficiency or resected prostate volume between the two techniques. Postoperative urodynamic outcomes showed slightly greater improvements in postvoid residual volume and maximum urinary flow rate with the three-lobe technique. No significant differences were found in International Prostate Symptom Score improvement or the incidence of postoperative urinary incontinence. Most included studies demonstrated a moderate risk of bias. Both <i>en bloc</i> and three-lobe enucleation techniques are effective and safe for the management of BPO. <i>En bloc</i> enucleation offers the advantage of reduced operative time, whereas the three-lobe technique may provide modestly better postoperative urodynamic outcomes. Further high-quality randomized controlled trials are required to confirm these findings and evaluate long-term outcomes.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 1","pages":"1-9"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of overall perception and interest in urology among medical students in Jeddah - A cross-sectional study.","authors":"Feras Filfilan, Rayan Alosaimi, Mohammed Mesawa, Huda Almazroie, Thamer Alghamdi, Alwaleed Alshamrani, Adel Elatreisy, Majed Sejiny, Turky Almouhissen, Abdulghani Khogeer","doi":"10.4103/ua.ua_50_25","DOIUrl":"10.4103/ua.ua_50_25","url":null,"abstract":"<p><strong>Background: </strong>Numerous factors influence the choice of a medical specialty, including lifestyle, prestige, and clinical exposure. Urology, a field that integrates medicine and surgery, has faced concerns regarding decreasing educational exposure, particularly in medical schools worldwide. This study aims to assess medical students' awareness, perception, and knowledge of urology in Jeddah, Saudi Arabia, and identify factors influencing the decision to pursue urology as a career.</p><p><strong>Methodology: </strong>This cross-sectional survey was conducted among 193 medical students and interns from universities in Jeddah. Utilizing a structured questionnaire, participants were assessed on demographic information, clinical exposure, urological knowledge, and career aspirations. The data analysis employed descriptive statistics and Chi-square tests, with a significance level set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>A high level of awareness about urology (90.2%) was observed among participants, with 74 students (38.3%) describing their knowledge as adequate, defined as rating their urological knowledge as \"good\" or \"very good.\" Although 72.5% of participants did not consider urology as a career, exposure through urology rotations was associated with greater interest in the field. Male participants were more likely to consider urology (<i>P</i> = 0.053) and had higher clinical exposure than females (<i>P</i> = 0.001). Clinical rotations positively influenced awareness, with 41.5% of students who completed a rotation expressing interest in pursuing urology versus 20.3% of those without rotation exposure (<i>P</i> = 0.002).</p><p><strong>Conclusion: </strong>While many medical students are aware of urology, increased clinical exposure is needed. About one-third expressed interest, mainly due to its medical-surgical integration and appealing lifestyle. Male students showed greater interest and participation in clinical rotations, which significantly enhanced their knowledge and career inclination.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 1","pages":"56-67"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Criteria for patients offered perineal urethrostomy over urethroplasty for urethral strictures.","authors":"Zachary Boston, Kunj Jain, Meher Pandher, Aleksandar Popovic, Amjad Alwaal","doi":"10.4103/ua.ua_29_25","DOIUrl":"10.4103/ua.ua_29_25","url":null,"abstract":"<p><strong>Background: </strong>Urethroplasty is considered the gold standard treatment for urethral stricture. Occasionally perineal urethrostomy can be offered to patients who cannot or are unwilling to undergo complex reconstruction. In this study, we explore the factors that have influenced urologists to offer perineal urethrostomy over urethroplasty for urethral strictures on the national level.</p><p><strong>Methods: </strong>The American College of Surgeons National Surgical Quality Improvement Program database 2006-2021 was used to identify patients undergoing surgical procedures for urethral strictures using current procedural terminology (CPT) codes. The CPT codes for urethroplasty (53410) and perineal urethrostomy (53010) were used to analyze the data appropriately. Cases were excluded if they were missing any demographic data. Patient characteristics of interest were race, age, smoking status, obesity, hypertension (HTN), chronic obstructive pulmonary disease COPD, American Society of Anesthesiologists classification, use of glucocorticoids, history of cancer, and diabetes mellitus. The Chi-square and multivariate logistic regressions were used to identify significant predictors of outcomes. Significance was defined as <i>P</i> < 0.05.</p><p><strong>Results: </strong>In total, 2941 patients received urethroplasty, and 154 patients received perineal urethrostomy for urethral stricture. Patients with significant comorbidities such as diabetes mellitus, HTN, and COPD are significantly more likely to undergo perineal urethrostomy [Table 1]. Patients younger than 70 were more likely to undergo urethroplasty. History of cancer, congestive heart failure, race, and dialysis had no impact on the choice of repair here.</p><p><strong>Conclusion: </strong>Male patients with urethral stricture who are less healthy and had increased comorbidities such as history of diabetes, HTN, and COPD were more likely to receive perineal urethrostomy over urethroplasty, while younger patients were less likely to be offered perineal urethrostomy.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 1","pages":"33-36"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological distress among bladder cancer patients: A systematic review.","authors":"Madhyra Tri Indraswari, Fakhri Rahman, Agus Rizal Ardy Hariandy Hamid, Chaidir Arif Mochtar","doi":"10.4103/ua.ua_9_25","DOIUrl":"10.4103/ua.ua_9_25","url":null,"abstract":"<p><strong>Purpose: </strong>Psychological distress, including depression and anxiety, is a significant yet often overlooked issue among bladder cancer patients. Despite its negative impact on treatment adherence, hospital stays, and overall survival, psychiatric distress remains underrepresented in clinical guidelines. This systematic review aims to assess the prevalence of psychiatric distress and its impact on bladder cancer patients while evaluating the role of psychiatric interventions in improving patient outcomes.</p><p><strong>Methods: </strong>A systematic search was conducted across PubMed, Embase, ProQuest, Scopus, and Wiley Online Library following Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Studies assessing psychiatric distress in bladder cancer patients and reporting the effects of psychiatric interventions were included. Data were extracted and analyzed qualitatively.</p><p><strong>Results: </strong>Sixteen studies encompassing 96,175 participants were included. Anxiety prevalence ranged from 7% to 38.3%, while depression ranged from 6.9% to 42.8%, with both increasing posttreatment. These studies collectively revealed heightened rates of depression and anxiety among bladder cancer patients, along with compromised sleep quality and increased incidence of psychiatric disorders posttreatment. Despite the challenges posed by psychological distress, our review identified several studies highlighting the efficacy of psychiatric interventions, including counseling and support services, in ameliorating mental health challenges among bladder cancer patients. However, our study encountered limitations such as language restrictions and heterogeneity among included studies, precluding meta-analysis.</p><p><strong>Conclusions: </strong>Bladder cancer imposes a significant psychological burden, yet mental health support remains underprioritized in clinical practice. Routine psychiatric screening and targeted interventions should be integrated into bladder cancer management to enhance patient well-being, treatment adherence, and overall outcomes.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 1","pages":"10-17"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of holmium laser enucleation of the prostate and bipolar transurethral resection of the prostate in relation to benign prostatic hyperplasia treatment.","authors":"Ahsan Ahmad, Nikhil Ranjan, Kumar Dheeraj, Gaurav Babelay","doi":"10.4103/ua.ua_55_25","DOIUrl":"10.4103/ua.ua_55_25","url":null,"abstract":"<p><strong>Background: </strong>A common disorder in men that has been linked to the natural aging process is benign prostatic hyperplasia (BPH). In men aged 70 and older, the frequency is approximately 40%.</p><p><strong>Aims: </strong>In this study, we compared the results of bipolar transurethral resection of the prostate (TURP) with our experience using holmium laser enucleation of the prostate (HoLEP).</p><p><strong>Settings and design: </strong>The research was prospective and randomized. It was conducted from April 2024 to January 2025 to treat BPH.</p><p><strong>Methodology: </strong>Fifty participants in total had taken part in the study. Patients were randomized using the odd-even method into two groups; Group A was administered with HoLEP, and Group B with bipolar TURP. Both groups were distributed equally, with 25 patients in each.</p><p><strong>Statistical analysis: </strong>For statistical analysis, an independent <i>t</i>-test was employed. Any <i>P</i> value below 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Operative time was 70.74 ± 16.54 min in Group A, whereas 52.46 ± 12.24 min in Group B. The operative time and capsular perforation were found to be statistically significant between the groups with a <i>P</i> < 0.001 and 0.04, respectively. The International Prostate Symptom Score scores were 5.65 ± 2.23 in Group A and 5.43 ± 2.02 in Group B, respectively. Qmax was found to be 20.32 ± 8.7 in Group A, while 18.66 ± 5.45 in Group B.</p><p><strong>Conclusion: </strong>In the study, both HoLEP and TURP tend to be equally effective in terms of symptomatic relief. A steep learning curve has been seen along with less morbidity, which is associated with HoLEP.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 1","pages":"83-87"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neighborhood-level socioeconomic status impacts the severity of lower urinary tract symptoms in men.","authors":"Carl A Ceraolo, Gabrielle C Ma, David Y Song, Soumya Konar, Rajat K Jain, Scott O Quarrier","doi":"10.4103/ua.ua_81_25","DOIUrl":"10.4103/ua.ua_81_25","url":null,"abstract":"<p><strong>Objectives: </strong>Social determinants of health (SDOH) impact whether a patient will report lower urinary tract symptoms (LUTS). Since management of benign prostatic hyperplasia is guided by symptoms, it is important to understand the drivers of symptom severity. This study investigated the relationship between neighborhood-level SDOH and the severity of LUTS in men.</p><p><strong>Materials and methods: </strong>Men who completed the International Prostate Symptom Score (IPSS) at a single institution from October 25, 2018, to July 31, 2024, were retrospectively analyzed. High social vulnerability index (SVI) neighborhoods were defined as those in the 75^th percentile or above. IPSS scores were compared between high and low SVI groups. Results were stratified into storage, voiding, or quality of life (QOL) domains. Adjustment for confounding was achieved with linear regression models adjusting for age, race, ethnicity, and number of medical comorbidities.</p><p><strong>Results: </strong>The study included 20,795 patients, with 1351 (6.5%) from high SVI communities. The high SVI group reported worse overall (10.5 vs. 9.6; <i>P</i> < 0.001), storage (5.4 vs. 5.0; <i>P</i> < 0.001), voiding (5.1 vs. 4.6; <i>P</i> < 0.001), and QOL (2.8 vs. 2.5; <i>P</i> < 0.001) scores. Age and number of comorbidities were independently associated with worse AUA-SI scores, while nonwhite race and Latinx ethnicity showed no association on multivariable analysis.</p><p><strong>Conclusions: </strong>High SVI patients report more severe LUTS at initial urologic referral. Delayed access to primary and urologic care in high SVI patients may lead to worse symptoms. Our findings highlight the importance of lowering barriers to urologic care for underserved groups.</p>","PeriodicalId":23633,"journal":{"name":"Urology Annals","volume":"18 1","pages":"37-40"},"PeriodicalIF":0.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}