Veterinary anaesthesia and analgesia最新文献

{"title":"Objective assessment of chronic pain in donkeys using the Donkey Chronic Pain Scale","authors":"","doi":"10.1016/j.vaa.2024.05.011","DOIUrl":"10.1016/j.vaa.2024.05.011","url":null,"abstract":"<div><h3>Objective</h3><p>To clinically evaluate previously developed pain scales [Donkey Chronic Pain Composite Pain Scale (DCP-CPS), Donkey Chronic Pain Facial Assessment of Pain (DCP-FAP) and combined Donkey Chronic Pain Scale (DCPS)], including behavioural and facial expression–based variables, for the assessment of chronic pain in donkeys.</p></div><div><h3>Study design</h3><p>Prospective, blinded clinical study.</p></div><div><h3>Animal</h3><p>A group of 77 donkeys (34 patients and 43 healthy control animals).</p></div><div><h3>Methods</h3><p>Animals were assessed by two observers that were blinded to the condition of the animals.</p></div><div><h3>Results</h3><p>Both DCP-CPS and DCP-FAP, and resulting combined DCPS scores, showed good interobserver reliability [intraclass correlation coefficient (ICC) = 0.91, 95% confidence interval (CI) = 0.86–0.95, <em>p</em> &lt; 0.001; ICC = 0.71, CI = 0.50–0.83, <em>p</em> &lt; 0.001 and ICC = 0.84, CI = 0.72–0.91, <em>p</em> &lt; 0.001, respectively]. All scores (DCP-CPS, DCP-FAP and the resulting combined DCPS) were significantly higher for patients than for controls at all time points (<em>p</em> &lt; 0.001 for all three scales). Sensitivity and specificity for identification of pain (cut-off value &gt;3) was 73.0% and 65.1% for DCP-CPS, and 60.9% and 83.3% for DCP-FAP, respectively. For the combined DCPS, sensitivity was 87.0% and specificity 90.9% (cut-off value &gt;6).</p></div><div><h3>Conclusions and clinical relevance</h3><p>Based on behavioural and facial expression–based variables, DCPS proved a promising and reproducible tool to assess different types of chronic pain in donkeys. The combination of behavioural and facial expression–based variables showed the best discriminatory characteristics in the current study. Further studies are needed for refinement of these tools.</p></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1467298724000886/pdfft?md5=d0660664e9e44f90e3af8149d758d4f0&pid=1-s2.0-S1467298724000886-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary experience with quadratus lumborum catheters for intermittent analgesia in three dogs with acute abdominal pain","authors":"","doi":"10.1016/j.vaa.2024.05.010","DOIUrl":"10.1016/j.vaa.2024.05.010","url":null,"abstract":"","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of inhaled salbutamol and salmeterol for the treatment of arterial hypoxaemia in anaesthetized horses: a randomized clinical trial","authors":"","doi":"10.1016/j.vaa.2024.05.009","DOIUrl":"10.1016/j.vaa.2024.05.009","url":null,"abstract":"<div><h3>Objective</h3><p>To compare the efficacy of inhaled salbutamol with salmeterol for the treatment of arterial hypoxaemia in anaesthetized horses.</p></div><div><h3>Study design</h3><p>Prospective, randomized, clinical study.</p></div><div><h3>Animals</h3><p>A total of 108 client-owned horses (American Society of Anesthesiologists status I–V) anaesthetized for elective and emergency procedures.</p></div><div><h3>Methods</h3><p>Horses were premedicated with acepromazine [intramuscularly 0.1 mg kg^–1 or intravenously (IV) 0.05 mg kg^–1] and xylazine (0.6 mg kg^–1 IV). Midazolam (0.06 mg kg^–1 IV) and ketamine (2.2 mg kg^–1 IV) were combined to induce anaesthesia, and isoflurane in oxygen/air mixture (inspired oxygen fraction 0.7) was used for maintenance of anaesthesia. Mechanical ventilation was initiated without delay using the following ventilator settings: tidal volume 10 mL kg^–1, respiratory rate 8 breaths minute^–1, inspiratory-to-expiratory time ratio 1:2, no positive end-expiratory pressure. If arterial blood gas analysis revealed PaO₂ &lt; 100 mmHg (13.3 kPa), the administration of either inhaled salbutamol (2 μg kg^–1) or salmeterol (0.5 μg kg^–1) was randomly assigned Blood gas analysis was repeated 15 and 30 minutes after treatment. The intervention was considered successful when PaO₂ after treatment ≥ 1.2 × PaO₂ before treatment (i.e. ≥20% increase). PaO₂ at 15 and 30 minutes was compared between groups using Mann–Whitney <em>U</em> test; <em>p</em> &lt; 0.05 was considered significant.</p></div><div><h3>Results</h3><p>Of the 108 horses, 60 were administered salbutamol, 65% and 60% responded successfully at 15 and 30 minutes, increasing their initial PaO₂ by 38% and 44%, respectively. The other 48 horses were administered salmeterol, 35% responded successfully at 15 and 30 minutes, increasing their initial PaO₂ by 3% and 4%, respectively. PaO₂ was significantly higher after salbutamol than after salmeterol at 15 and 30 minutes.</p></div><div><h3>Conclusions and clinical relevance</h3><p>Using the described protocol, inhaled salbutamol was more effective than salmeterol in improving PaO₂ in anaesthetized horses with value &lt; 100 mmHg (13.3 kPa).</p></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Veterinary students’ attitudes toward anesthesiology as a specialty","authors":"","doi":"10.1016/j.vaa.2024.05.008","DOIUrl":"10.1016/j.vaa.2024.05.008","url":null,"abstract":"<div><h3>Objective</h3><p>To identify the perceptions of veterinary students interested in specialization regarding veterinary anesthesiology.</p></div><div><h3>Study design</h3><p>Cross-sectional, multi-institutional, voluntary, anonymous, nonrandomized survey.</p></div><div><h3>Population</h3><p>Veterinary students (303 of 557 total respondents) from 10 veterinary schools.</p></div><div><h3>Methods</h3><p>Quantitative data were obtained via 5-point Likert scale questions about anesthesia-related topics. Open-ended questions were used to obtain qualitative data. A multivariate logistic regression model assessed the likelihood of choosing a career as an anesthesiologist. Spearman’s rank correlation coefficient was used to assess the relationship between ‘anesthesia is interesting’ and other variables.</p></div><div><h3>Results</h3><p>Of the respondents, 14 (6%) indicated veterinary anesthesia as their chosen specialty. There was a significant positive relationship between ‘anesthesia is interesting’ and the following variables: age, enjoyment in anesthesia class, belief in the importance of anesthesia for their career, belief in the importance of analgesia for their career, belief that anesthesia and analgesia have a large impact on patient care, interest in pharmacology, interest in physiology, interest in learning technical skills, belief that anesthesiologists are respected by their colleagues and belief that anesthesiologists are an important part of the health care team. More weeks on the anesthesia clinical rotation was positively and significantly associated with increased rotation enjoyment. Enjoyment in the anesthesia class [<em>p</em> = 0.001, Exp(β) = 2.1, 95% confidence interval (CI): 1.3–3.4] and belief that anesthesia is interesting [<em>p</em> = 0.013, Exp(β) = 2.6, 95% CI: 1.2–5.4] were predictors that respondents would be more likely to consider a career as a veterinary anesthesiologist.</p></div><div><h3>Conclusions</h3><p>Those veterinary students with an interest in pharmacology and who enjoyed their anesthesia course were more likely to consider a career as a veterinary anesthesiologist. If students indicated no interest in specializing in veterinary anesthesia, they appreciated the value the specialty brings to animal care and believed that veterinary anesthesiologists are respected by their peers.</p></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound- and fluoroscopy-guided retrograde epidural catheter placement in a dog as a rescue analgesia after multiple perineal surgeries","authors":"","doi":"10.1016/j.vaa.2024.05.007","DOIUrl":"10.1016/j.vaa.2024.05.007","url":null,"abstract":"","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tidal volume selection in volume-controlled ventilation guided by driving pressure versus actual body weight in healthy anesthetized and mechanically ventilated dogs: A randomized crossover trial","authors":"","doi":"10.1016/j.vaa.2024.05.006","DOIUrl":"10.1016/j.vaa.2024.05.006","url":null,"abstract":"<div><h3>Objective</h3><p>To compare static compliance of the respiratory system (C_stRS) and the ratio of partial pressure of end-tidal to arterial carbon dioxide (P<span>e′</span>CO₂/PaCO₂<span><span>), in healthy dogs using two approaches for </span>tidal volume (V</span>_T) selection during volume-controlled ventilation: body mass based and driving pressure (ΔPaw) guided.</p></div><div><h3>Study design</h3><p>Randomized, nonblinded, crossover, clinical trial.</p></div><div><h3>Animals</h3><p>A total of 19 client-owned dogs anesthetized for castration and ovariohysterectomy.</p></div><div><h3>Methods</h3><p>After a stable 10 minute baseline, each dog was mechanically ventilated with a V_T selection strategy, randomized to a constant V_T of 15 mL kg^–1 of actual body mass (V_TBW) or ΔPaw-guided V_T (V_TΔP) of 7–8 cmH₂O. Both strategies used an inspiratory time of 1 second, 20% end-inspiratory pause, 4 cmH₂O positive end-expiratory pressure and fraction of inspired oxygen of 0.4. Respiratory frequency was adjusted to maintain P<span>e′</span>CO₂<span> between 35 and 40 mmHg. Respiratory mechanics, arterial blood gases and P</span><span>e′</span>CO₂/PaCO₂ were assessed. Continuous variables are presented as mean ± SD or median (interquartile range; quartiles 1–3), depending on distribution, and compared with Wilcoxon signed-rank tests.</p></div><div><h3>Results</h3><p>The V_T was significantly higher in dogs ventilated with V_TΔP than with V_TBW strategy (17.20 ± 4.04 <em>versus</em> 15.03 ± 0.60 mL kg^–1, <em>p</em> = 0.036). C_stRS was significantly higher with V_TΔP than with V_TBW strategy [2.47 (1.86–2.86) <em>versus</em> 2.25 (1.79–2.58) mL cmH₂O⁻¹ kg^–1, <em>p</em> = 0.011]. There were no differences in P<span>e′</span>CO₂/PaCO₂ between V_TΔP and V_TBW strategies (0.94 ± 0.06 <em>versus</em> 0.92 ± 0.06, <em>p</em> = 0.094). No discernible difference in ΔPaw was noted between the strategies.</p></div><div><h3>Conclusions and clinical relevance</h3><p>While no apparent difference was observed in the P<span>e′</span>CO₂/PaCO₂ between the V_T selection strategies employed, C_stRS significantly increased during the V_TΔP approach. A future trial should explore if V_TΔP improves perioperative gas exchange and prevents lung damage.</p></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141135131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laryngocardiac reflex following placement of a transesophageal electrocardiogram probe in an isoflurane-anesthetized Vietnamese Pot-Bellied pig","authors":"","doi":"10.1016/j.vaa.2024.05.005","DOIUrl":"10.1016/j.vaa.2024.05.005","url":null,"abstract":"","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2023 awards for outstanding contributions to veterinary anesthesiology","authors":"Peter Pascoe","doi":"10.1016/j.vaa.2024.04.008","DOIUrl":"10.1016/j.vaa.2024.04.008","url":null,"abstract":"","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1467298724000771/pdfft?md5=f316f7f1ed7788a0acfdce4e9c891dbd&pid=1-s2.0-S1467298724000771-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proptosis during endotracheal intubation in a brachycephalic dog","authors":"","doi":"10.1016/j.vaa.2024.05.004","DOIUrl":"10.1016/j.vaa.2024.05.004","url":null,"abstract":"","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141131358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective case-control study evaluating systemic blood pressure and heart rate in dogs with brain herniation under general anesthesia","authors":"","doi":"10.1016/j.vaa.2024.05.003","DOIUrl":"10.1016/j.vaa.2024.05.003","url":null,"abstract":"<div><h3>Objective</h3><p><span>To examine whether increased systemic arterial blood pressure (ABP) and decreased heart rate (HR) under inhalant anesthesia were suggestive of the Cushing reflex (CR) in </span>dogs with neurological diseases based on magnetic resonance imaging (MRI) findings.</p></div><div><h3>Study design</h3><p>Retrospective case-control study.</p></div><div><h3>Animals</h3><p>A sample of 137 client-owned dogs admitted to two veterinary teaching hospitals for diagnosis and patient care owing to suspected intracranial disease from 2005 to 2020. All dogs underwent general anesthesia for MRI of the brain.</p></div><div><h3>Methods</h3><p>Based on MRI study reports, dogs were divided into three study groups: group A, dogs with suspected brain herniation; group B, dogs with an abnormal MRI finding but without suspicion of herniation; and group C, dogs with structurally unremarkable brains (control). Initial evaluation by an anesthesiologist resulted in 58 cases selected for further review based on suspicion of having intracranial hypertension, as indicated by ABP and HR changes under anesthesia. Anesthetic records were randomized and independently reviewed by three board-certified anesthesiologists blinded to MRI diagnosis who allocated each dog into one of three groups: 1) likely to have CR; 2) unlikely to have CR; or 3) insufficient data for determination.</p></div><div><h3>Results</h3><p>Of the 58 cases evaluated, nine were considered likely to have CR and 48 were considered unlikely to have CR. In one case, the anesthesiologists were unable to determine whether CR occurred. Of the nine dogs with likely CR, three had an MRI diagnosis of intracranial herniation. The remaining six dogs suspected of CR belonged to the normal brain group.</p></div><div><h3>Conclusions and clinical relevance</h3><p>The ABP and HR changes associated with CR are not reliably associated with brain herniation in dogs undergoing general anesthesia.</p></div>","PeriodicalId":23626,"journal":{"name":"Veterinary anaesthesia and analgesia","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}