Vascular MedicinePub Date : 2025-05-09DOI: 10.1177/1358863X251320917
Natalie S Evans, Alexandra L Solomon, Elizabeth V Ratchford
{"title":"Vascular Disease Patient Information Page: Peripheral artery disease - 2025 update.","authors":"Natalie S Evans, Alexandra L Solomon, Elizabeth V Ratchford","doi":"10.1177/1358863X251320917","DOIUrl":"https://doi.org/10.1177/1358863X251320917","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251320917"},"PeriodicalIF":3.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carotid artery calcification as a predictor of systemic vascular events.","authors":"Noritaka Sano, Tamaki Kobayashi, Hiroharu Kataoka, Akiko Ishigami, Yusuke Shimahara, Naomi Morita, Masanobu Yamada, Kunihiro Nishimura, Koji Iihara","doi":"10.1177/1358863X251325808","DOIUrl":"https://doi.org/10.1177/1358863X251325808","url":null,"abstract":"<p><strong>Background: </strong>Coronary calcification is a well-known predictor of coronary events, yet the impact of carotid artery calcification on systemic vascular events (e.g., cerebral ischemic, coronary, and peripheral artery events) remains unclear. The aim of this study was to determine whether carotid calcification can be used to predict systemic vascular events.</p><p><strong>Methods: </strong>This single-center, retrospective cohort study included 194 patients who had a history of vascular disease, including carotid stenosis or occlusion, coronary artery disease, valvular heart disease, ischemic stroke, or transient ischemic attack. We collected data pertaining to risk factors and laboratory parameters. Calcification of the carotid arteries was assessed via whole-body computed tomography, and the modified carotid Agatston calcium score (CCS) was determined. Participants were divided into two CCS groups according to the cut-off value determined via receiver operating characteristic curve analysis; high CCS ≥ 126 and low CCS < 126. Coronary, ischemic cerebrovascular, and peripheral vascular events were recorded over a 5-year follow-up period, and their incidence was compared between the groups using Cox proportional hazards regression analysis.</p><p><strong>Results: </strong>Older age, hypertension, and chronic kidney disease had a significant positive impact on the CCS. Systemic vascular events (hazard ratio [HR]: 2.70, CI: 1.07-6.79, <i>p</i> = 0.022), coronary events (HR: 4.29, CI: 0.87-21.1, <i>p</i> = 0.045), and peripheral vascular events (<i>p</i> = 0.032) were significantly more frequent in the high versus low CCS group.</p><p><strong>Conclusion: </strong>The CCS may be a useful tool for predicting future systemic vascular events, including those related to coronary and peripheral artery diseases.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251325808"},"PeriodicalIF":3.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-05-09DOI: 10.1177/1358863X251328671
Abena Appah-Sampong, Ascharya Balaji, Jack H Casey, Navya Kotturu, Danielle Montano, Mohit Manchella, Bassil Bacare, James J Fitzgibbon, Patrick Heindel, Tanujit Dey, Behnood Bikdeli, Mohamad A Hussain
{"title":"A scoping review of electronic phenotyping methodologies used to identify peripheral artery disease in observational studies.","authors":"Abena Appah-Sampong, Ascharya Balaji, Jack H Casey, Navya Kotturu, Danielle Montano, Mohit Manchella, Bassil Bacare, James J Fitzgibbon, Patrick Heindel, Tanujit Dey, Behnood Bikdeli, Mohamad A Hussain","doi":"10.1177/1358863X251328671","DOIUrl":"https://doi.org/10.1177/1358863X251328671","url":null,"abstract":"<p><p>Billing data including International Classification of Diseases (ICD) codes are increasingly used to identify cohorts of patients with peripheral artery disease (PAD) in electronic health records (EHRs) and administrative claims databases (ACDs). However, the validity of common PAD phenotyping approaches is a central challenge to the utilization of EHR and ACD data. We present a scoping review of contemporary PAD observational studies to describe the electronic phenotyping strategies employed in PAD identification and propose recommendations for improvement. We searched two databases, MEDLINE and Web of Science, identifying a total of 748 articles that underwent title and abstract review. Of these articles, 163 met the criteria for full-text review, with 84 articles ultimately included in the study. We demonstrate that 19.0% of eligible studies utilized ICD, Ninth Revision (ICD-9) codes, 11.9% utilized ICD, Tenth Revision (ICD-10) codes, and 69.0% of studies utilized a combination of ICD-9 and ICD-10 codes in their electronic phenotyping methodology. Of the included studies, 76.2% utilized a single-code query approach for electronic phenotyping despite low diagnostic yield, and 21.4% utilized rule-based methods. Only five studies utilized logistic regression modeling, despite the demonstrated effectiveness of this method. The current study demonstrates high utilization of unreliable electronic phenotyping methods such as single-code-based queries, which severely limits research quality. Improvements in electronic phenotyping methods are necessary to leverage data from EHRs and ACDs for high-quality research.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251328671"},"PeriodicalIF":3.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-05-01DOI: 10.1177/1358863X251330583
Mary M McDermott, Daniella Kadian-Dodov, Herbert A Aronow, Joshua A Beckman, Demetria M Bolden, Yulanka S Castro-Dominguez, Mark A Creager, Michael H Criqui, Philip P Goodney, Heather L Gornik, Naomi M Hamburg, Nicholas J Leeper, Jeffrey W Olin, Elsie Ross, Marc P Bonaca
{"title":"Research priorities for peripheral artery disease: A statement from the Society for Vascular Medicine.","authors":"Mary M McDermott, Daniella Kadian-Dodov, Herbert A Aronow, Joshua A Beckman, Demetria M Bolden, Yulanka S Castro-Dominguez, Mark A Creager, Michael H Criqui, Philip P Goodney, Heather L Gornik, Naomi M Hamburg, Nicholas J Leeper, Jeffrey W Olin, Elsie Ross, Marc P Bonaca","doi":"10.1177/1358863X251330583","DOIUrl":"https://doi.org/10.1177/1358863X251330583","url":null,"abstract":"<p><p>Lower-extremity peripheral artery disease (PAD) affects approximately 236 million people worldwide and at least eight million people in the United States (US). Despite availability of new therapies that prevent major adverse cardiovascular events (MACE), these and major adverse limb events (MALE) remain common and occur more frequently in people with PAD, either with or without coronary artery disease (CAD), compared to people with CAD who do not have PAD. The most effective therapies to prevent cardiovascular events are not identical in people with PAD and those with CAD. Walking impairment and the risk of lower-extremity amputation are significantly greater in people with PAD compared to those without PAD. This report from the Society for Vascular Medicine (SVM) proposes and summarizes high-priority topics for scientific investigation in PAD, with the goal of improving health outcomes in people with PAD. To develop this report, a multidisciplinary team of scientists and clinicians reviewed literature, proposed high-priority topics for scientific investigation, and voted to rank the highest priority topics for scientific investigation. Priorities for clinical scientific investigation include: determine the current prevalence of PAD in the US by age, sex, race, and ethnicity; improve methods to diagnose PAD; develop new medical therapies to eliminate walking impairment; and improve implementation of established therapies to reduce rates of MACE and MALE in people with PAD. Priorities in basic science and translational science investigation include: developing animal models that closely resemble the vascular, skeletal muscle, and platelet pathology in patients with PAD and defining the genetic and epigenetic contributors to PAD and PAD-associated outcomes. Successful investigation of these research priorities will require more well-trained investigators focused on scientific investigation of PAD, greater and more efficient enrollment of diverse patients with PAD in randomized clinical trials, and increased research funding dedicated to PAD.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251330583"},"PeriodicalIF":3.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sex-based difference in functional performance and quality of life 1 year after supervised exercise training in patients with symptomatic peripheral artery disease.","authors":"Stefano Lanzi, Anina Pousaz, Luca Calanca, Lucia Mazzolai","doi":"10.1177/1358863X251322394","DOIUrl":"https://doi.org/10.1177/1358863X251322394","url":null,"abstract":"<p><strong>Introduction: </strong>The long-term effects of supervised exercise training (SET) on functional performance and health-related quality of life (HRQoL) in symptomatic peripheral artery disease (PAD) are poorly investigated, especially in women. This study investigated these outcomes 1 year after SET in both women and men.</p><p><strong>Methods: </strong>In this single-arm, prospective, nonrandomized study, patients with symptomatic PAD participating in the 3-month SET program were investigated. Functional performance (6-minute walking distance [6MWD], the stair-climbing test [SCT], and the short physical performance battery [SPPB]), and HRQoL (physical component summary [PCS] score of the Short Form-36 questionnaire) were assessed before and following SET, as well as at 6 and 12 months after SET completion.</p><p><strong>Results: </strong>Ninety patients (women: <i>n</i> = 30; men: <i>n</i> = 60) with chronic symptomatic PAD (ankle-brachial index 0.78 ± 0.22; mean age 65.4 ± 10.2 years) were included in the study. The 6MWD (<i>women</i>: before: 387.2 ± 88.6 m; after: 472.4 ± 57.0 m; 12 months: 469.9 ± 57.8 m; <i>men</i>: before: 431.7 ± 94.0 m; after: 477.5 ± 88.6 m; 12 months: 467.2 ± 73.4 m), SPPB score (<i>women</i>: before: 9.6 ± 2.4; after: 11.3 ± 1.0; 12 months: 11.2 ± 0.5; <i>men</i>: before: 10.6 ± 1.4; after: 11.5 ± 0.9; 12 months: 11.3 ± 0.8), and SCT (<i>women</i>: before: 8.6 ± 4.4 s; after: 5.6 ± 1.6 s; 12 months: 5.8 ± 1.2 s; <i>men</i>: before: 6.2 ± 2.3 s; after: 5.0 ± 1.9 s; 12 months: 5.3 ± 1.6 s) significantly improved over time (<i>p</i> ≤ 0.001), with no significant differences between women and men. The PCS score (<i>women</i>: before: 30.3 ± 8.0; after: 38.8 ± 8.4; 12 months: 35.7 ± 7.4; <i>men</i>: before: 32.4 ± 10.5; after: 35.7 ± 9.5; 12 months: 35.4 ± 7.6) significantly improved in women only (<i>p</i> = 0.020).</p><p><strong>Conclusion: </strong>One year after SET, both women and men with PAD exhibit similar functional benefits, whereas HRQoL improvements were observed exclusively in women.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251322394"},"PeriodicalIF":3.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-04-30DOI: 10.1177/1358863X251324106
W James Melvin, Thomas W Wakefield, Andrea T Obi
{"title":"Air plethysmography: A phoenix or destined for ashes?","authors":"W James Melvin, Thomas W Wakefield, Andrea T Obi","doi":"10.1177/1358863X251324106","DOIUrl":"https://doi.org/10.1177/1358863X251324106","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251324106"},"PeriodicalIF":3.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-04-30DOI: 10.1177/1358863X251331561
Mario Enrico Canonico, Connie N Hess, Sivan Naveh, R Kevin Rogers, Mark R Nehler, Shea E Hogan, Judith A Hsia, Scott D Berkowitz, Marc P Bonaca
{"title":"Prescription of aspirin plus low-dose rivaroxaban in patients with peripheral artery disease after lower-extremity revascularization.","authors":"Mario Enrico Canonico, Connie N Hess, Sivan Naveh, R Kevin Rogers, Mark R Nehler, Shea E Hogan, Judith A Hsia, Scott D Berkowitz, Marc P Bonaca","doi":"10.1177/1358863X251331561","DOIUrl":"https://doi.org/10.1177/1358863X251331561","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251331561"},"PeriodicalIF":3.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-04-21DOI: 10.1177/1358863X251326537
Mauricio Gonzalez-Urquijo, Gustavo Salgado-Garza, Ariana Marie Martin, Jos C van den Berg, Jose Francisco Vargas, Leopoldo Marine, Francisco Valdes, Mario Alejandro Fabiani
{"title":"Infective native visceral artery aneurysm (INVAA): A systematic review of etiology, treatment, and outcomes.","authors":"Mauricio Gonzalez-Urquijo, Gustavo Salgado-Garza, Ariana Marie Martin, Jos C van den Berg, Jose Francisco Vargas, Leopoldo Marine, Francisco Valdes, Mario Alejandro Fabiani","doi":"10.1177/1358863X251326537","DOIUrl":"https://doi.org/10.1177/1358863X251326537","url":null,"abstract":"<p><p>The present review introduces the term 'infective native visceral artery aneurysm (INVAA)' and provides a systematic review of the literature on this topic. The terms 'mycotic' and 'infected' have been replaced by the term 'infective native' to more accurately describe aneurysms of this type. A systematic search of MEDLINE, Embase, Google Scholar, and Scopus databases was performed to identify articles reporting on INVAAs to April 2024. Inclusion criteria encompassed studies describing 'mycotic' or 'infected' primary visceral aneurysms, excluding patients with concurrent aneurysms in the aorta. The search yielded 356 articles, with 161 meeting the inclusion criteria, covering 175 patients. The median age was 48 years (IQR: 33-60 years), predominantly men (n = 127, 72.6%). INVAA was most frequently reported in the superior mesenteric artery (37.5%, <i>n</i> = 65), followed by the hepatic (22.9%, <i>n</i> = 40) and splenic arteries (14.3%, <i>n</i> = 25). Endocarditis was the predominant etiology in 67.4% (n = 118) of cases. Gram-positive pathogens were identified in 58.8% (n = 103) of cases. Treatment modalities included open surgery (49.7%, <i>n</i> = 87), endovascular interventions (37.7%, <i>n</i> = 66), and medical management (12.0%, <i>n</i> = 21). The overall proportion of patients who died was 13.7% (n = 24). In multivariable modeling, cerebral aneurysms (OR: 4.0, 95% CI 1.17, 12.8; <i>p</i> = 0.02), gastrointestinal bleed (OR: 5.79, 95% CI 1.86, 17.6; <i>p</i> < 0.01), and chronic kidney disease (OR: 16.0, 95% CI 2.3, 136; <i>p</i> < 0.01) were associated with increased odds of death. The optimal treatment for INVAA remains undefined, highlighting the need for standardization of reporting and prospective registries to enhance the understanding and management of this complex disease.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251326537"},"PeriodicalIF":3.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}