Vascular Medicine最新文献_第10页

Sitting knee-flexion angle does not influence endothelial-dependent vasodilation in laboratory or free-living conditions 在实验室或自由生活条件下，坐姿膝关节屈曲角度不会影响内皮依赖性血管扩张作用

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-10 DOI: 10.1177/1358863x241238702

Madeline E Shivgulam, Myles W O’Brien, Yanlin Wu, Haoxuan Liu, Jennifer L Petterson, Beverly D Schwartz, Derek S Kimmerly

{"title":"Sitting knee-flexion angle does not influence endothelial-dependent vasodilation in laboratory or free-living conditions","authors":"Madeline E Shivgulam, Myles W O’Brien, Yanlin Wu, Haoxuan Liu, Jennifer L Petterson, Beverly D Schwartz, Derek S Kimmerly","doi":"10.1177/1358863x241238702","DOIUrl":"https://doi.org/10.1177/1358863x241238702","url":null,"abstract":"Introduction:Single bouts of prolonged bent-legged sitting attenuate popliteal endothelial-dependent vasodilation (as assessed via flow-mediated dilation [FMD]), which is partially attributed to arterial ‘kinking’. However, the impact of knee-flexion angle on sitting-induced popliteal FMD is unknown. The objective of this study was to perform separate laboratory and free-living studies to test the hypotheses that: (1) popliteal FMD impairments would be graded between knee flexions at 90° (bent-legged sitting) > 45° > 0° (straight-legged sitting) following a 3-hour bout of sitting; and (2) more habitual time spent bent-legged sitting (< 45°) would be associated with lower FMD.Methods:The laboratory study included eight young, healthy adults (24 ± 2 years; four women) who underwent two sitting bouts over 2 days with one leg positioned at a knee-flexion angle of 0° or 90° and the opposite leg at 45° knee flexion. Popliteal FMD was assessed at pre- and postsitting timepoints.Results:Sitting-induced reductions in FMD were similar between all knee-flexion angles (all, p > 0.674). The free-living study included 35 young, healthy adults (23 ± 3 years; 16 women) who wore three activPAL monitors (torso, thigh, shin) to determine detailed sedentary postures. Time spent sedentary (624 ± 127 min/day), straight-legged sitting (112 ± 98 min/day), and bent-legged sitting (442 ± 106 min/day) were not related to relative FMD (5.3 ± 1.8%; all, p > 0.240).Conclusion:These findings suggest that knee-flexion angle-mediated arterial ‘kinking’ during sitting is not a major contributor toward sitting-induced popliteal endothelial-dependent vasodilatory dysfunction.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":"122 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140566127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vascular Medicine Patient Information Page: Popliteal artery aneurysm 血管内科患者信息页面：腘动脉瘤

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-04 DOI: 10.1177/1358863x241241019

Andrea D Kim, Alexandra L Solomon, Elizabeth V Ratchford

引用次数: 0

Images in Vascular Medicine: Takayasu retinopathy as a primary presentation of active vasculitis 血管医学图像：以活动性血管炎为主要表现的高安视网膜病变

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-04 DOI: 10.1177/1358863x241241022

Chinmay Mahatme, Virna M. Shah, Veerappan R. Saravanan

引用次数: 0

Deep venous thrombosis in patients with atresia of the inferior vena cava and right kidney hypoplasia (KILT syndrome): Systematic review of the literature 下腔静脉闭锁和右肾发育不全（KILT 综合征）患者的深静脉血栓形成：文献系统回顾

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-04 DOI: 10.1177/1358863x241240427

Nikola Pantic, Mirjana Cvetkovic, Jelena Milin-Lazovic, Jelica Vukmirovic, Aleksandar Pavlovic, Marijana Virijevic, Zlatko Pravdic, Sofija Kozarac, Nikica Sabljic, Nada Suvajdzic-Vukovic, Marko Dragas, Mirjana Mitrovic

{"title":"Deep venous thrombosis in patients with atresia of the inferior vena cava and right kidney hypoplasia (KILT syndrome): Systematic review of the literature","authors":"Nikola Pantic, Mirjana Cvetkovic, Jelena Milin-Lazovic, Jelica Vukmirovic, Aleksandar Pavlovic, Marijana Virijevic, Zlatko Pravdic, Sofija Kozarac, Nikica Sabljic, Nada Suvajdzic-Vukovic, Marko Dragas, Mirjana Mitrovic","doi":"10.1177/1358863x241240427","DOIUrl":"https://doi.org/10.1177/1358863x241240427","url":null,"abstract":"Inferior vena cava (IVC) anomalies are uncommon congenital causes of deep vein thrombosis (DVT). KILT syndrome (kidney and IVC abnormalities with leg thrombosis) has only been described as case reports in the literature. Therefore, the characteristics, evaluation, and management of patients with KILT syndrome have not yet been standardized. This study aimed to systematically review and analyze the clinical and radiographic data and treatment of previously reported cases of KILT syndrome. In this systematic review, we performed a literature search of the PubMed, Scopus, and Web of Science databases in December 2023, with no restrictions on the publication date. After duplicate extractions, 4195 articles were screened. Case reports and case series reporting on KILT syndrome were included. In addition to previously published cases, we included a new case of a previously healthy 25-year-old man with KILT syndrome in the analysis. A total of 34 cases were therefore included in this study. The majority (76.5%) were male patients with a median age of 24 years. In most patients, unprovoked bilateral iliofemoral thrombosis was diagnosed, and 64.7% had left kidney abnormalities. Our study suggests that anomalies of the IVC should be suspected in all young patients, especially male patients, with proximal, recurrent, or idiopathic DVT. If an IVC anomaly is confirmed, the kidneys should be examined to monitor and preserve healthy kidneys in cases of KILT syndrome. The data collected from all patients emphasize the requirement of long-term anticoagulation and risk factor control. Surgical measures may be effective for treating symptomatic refractory cases.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":"84 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140566325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pilot study to evaluate the safety and effectiveness of etidronate treatment for arterial calcification due to deficiency of CD73 (ACDC) 评估依替膦酸钠治疗 CD73 缺乏所致动脉钙化（ACDC）的安全性和有效性的试点研究

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-03 DOI: 10.1177/1358863x241235669

Elisa A Ferrante, Cornelia D Cudrici, Mahmood Rashidi, Yi-Ping Fu, Rebecca Huffstutler, Katherine Carney, Marcus Y Chen, Cynthia St Hilaire, Kevin Smith, Hadi Bagheri, James D Katz, Carlos R Ferreira, William A Gahl, Manfred Boehm, Alessandra Brofferio

{"title":"Pilot study to evaluate the safety and effectiveness of etidronate treatment for arterial calcification due to deficiency of CD73 (ACDC)","authors":"Elisa A Ferrante, Cornelia D Cudrici, Mahmood Rashidi, Yi-Ping Fu, Rebecca Huffstutler, Katherine Carney, Marcus Y Chen, Cynthia St Hilaire, Kevin Smith, Hadi Bagheri, James D Katz, Carlos R Ferreira, William A Gahl, Manfred Boehm, Alessandra Brofferio","doi":"10.1177/1358863x241235669","DOIUrl":"https://doi.org/10.1177/1358863x241235669","url":null,"abstract":"Background:Arterial calcification due to deficiency of CD73 (ACDC; OMIM 211800) is a rare genetic disease resulting in calcium deposits in arteries and small joints causing claudication, resting pain, severe joint pain, and deformities. Currently, there are no standard treatments for ACDC. Our previous work identified etidronate as a potential targeted ACDC treatment, using in vitro and in vivo disease models with patient-derived cells. In this study, we test the safety and effectiveness of etidronate in attenuating the progression of lower-extremity arterial calcification and vascular blood flow based on the computed tomography (CT) calcium score and ankle–brachial index (ABI).Methods:Seven adult patients with a confirmed genetic diagnosis of ACDC were enrolled in an open-label, nonrandomized, single-arm pilot study for etidronate treatment. They took etidronate daily for 14 days every 3 months and were examined at the NIH Clinical Center bi-annually for 3 years. They received a baseline evaluation as well as yearly follow up after treatment. Study visits included imaging studies, exercise tolerance tests with ABIs, clinical blood and urine testing, and full dental exams.Results:Etidronate treatment appeared to have slowed the progression of further vascular calcification in lower extremities as measured by CT but did not have an effect in reversing vascular and/or periarticular joint calcifications in our small ACDC cohort.Conclusions:Etidronate was found to be safe and well tolerated by our patients and, despite the small sample size, appeared to show an effect in slowing the progression of calcification in our ACDC patient cohort. (ClinicalTrials.gov Identifier NCT01585402)","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":"49 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140566252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced Raynaud's disease: A vascular medicine-initiated team-based approach and nationwide cohort analysis. 晚期雷诺氏病：单一机构和全国性队列分析。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-04-01 Epub Date: 2024-02-09 DOI: 10.1177/1358863X231220609

Milan Kaushik, Sebastian E Beyer, Jennifer Nashel, Cyrus Kholdani, Arriyan S Dowlatshahi, Eric A Secemsky, Brett J Carroll

引用次数: 0

Coronary artery calcium for stroke mortality prediction. 用于预测中风死亡率的冠状动脉钙。

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-01 Epub Date: 2024-02-09 DOI: 10.1177/1358863X231226217

John Erhabor, Ellen Boakye, Zeina Dardari, Omar Dzaye, Garshasb Soroosh, Daniel S Berman, Matthew J Budoff, Michael D Miedema, Khurram Nasir, John A Rumberger, Leslee J Shaw, Michelle C Johansen, Michael J Blaha

引用次数: 0

Images in Vascular Medicine: Nonuremic calciphylaxis secondary to occult malignancy. 血管医学图像：继发于隐匿性恶性肿瘤的非尿毒症性钙化症。

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-01 Epub Date: 2023-12-16 DOI: 10.1177/1358863X231215327

Syed Bukhari, Mohamed Ghoweba, John R Bartholomew, Deborah Hornacek

引用次数: 0

Evaluation of short-term mortality in patients with Medicare undergoing endovascular interventions for chronic limb-threatening ischemia. 评估因慢性肢体缺血而接受血管内介入治疗的医保患者的短期死亡率。

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-01 Epub Date: 2024-02-09 DOI: 10.1177/1358863X231224335

Jacob Cleman, Gaëlle Romain, Santiago Callegari, Lindsey Scierka, Francky Jacque, Kim G Smolderen, Carlos Mena-Hurtado

{"title":"Evaluation of short-term mortality in patients with Medicare undergoing endovascular interventions for chronic limb-threatening ischemia.","authors":"Jacob Cleman, Gaëlle Romain, Santiago Callegari, Lindsey Scierka, Francky Jacque, Kim G Smolderen, Carlos Mena-Hurtado","doi":"10.1177/1358863X231224335","DOIUrl":"10.1177/1358863X231224335","url":null,"abstract":"Introduction: Patients with chronic limb-threatening ischemia (CLTI) have high mortality rates after revascularization. Risk stratification for short-term outcomes is challenging. We aimed to develop machine-learning models to rank predictive variables for 30-day and 90-day all-cause mortality after peripheral vascular intervention (PVI).Methods: Patients undergoing PVI for CLTI in the Medicare-linked Vascular Quality Initiative were included. Sixty-six preprocedural variables were included. Random survival forest (RSF) models were constructed for 30-day and 90-day all-cause mortality in the training sample and evaluated in the testing sample. Predictive variables were ranked based on the frequency that they caused branch splitting nearest the root node by importance-weighted relative importance plots. Model performance was assessed by the Brier score, continuous ranked probability score, out-of-bag error rate, and Harrell's C-index.Results: A total of 10,114 patients were included. The crude mortality rate was 4.4% at 30 days and 10.6% at 90 days. RSF models commonly identified stage 5 chronic kidney disease (CKD), dementia, congestive heart failure (CHF), age, urgent procedures, and need for assisted care as the most predictive variables. For both models, eight of the top 10 variables were either medical comorbidities or functional status variables. Models showed good discrimination (C-statistic 0.72 and 0.73) and calibration (Brier score 0.03 and 0.10).Conclusion: RSF models for 30-day and 90-day all-cause mortality commonly identified CKD, dementia, CHF, need for assisted care at home, urgent procedures, and age as the most predictive variables as critical factors in CLTI. Results may help guide individualized risk-benefit treatment conversations regarding PVI.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"172-181"},"PeriodicalIF":3.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of vascular medicine specialists on inpatient utilization and management of inferior vena cava filters. 血管医学对住院病人使用和管理下腔静脉滤器的影响。

IF 3.5 3区医学

Vascular Medicine Pub Date : 2024-04-01 Epub Date: 2024-02-09 DOI: 10.1177/1358863X231224326

Danielle T Vlazny, Damon E Houghton

引用次数: 0