Vascular Medicine最新文献_第10页

Society Communications: 2024 Committee Updates. 学会通讯：2024 委员会更新。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-09-06 DOI: 10.1177/1358863X241268675

Kevin P Cohoon, Daniella Kadian-Dodov, Robert Eberhardt, Aditya Sharma

引用次数: 0

Underutilization of supervised exercise therapy for symptomatic peripheral artery disease among Medicare beneficiaries. 医疗保险受益人对有症状外周动脉疾病的监督运动疗法利用不足。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-08-12 DOI: 10.1177/1358863X241266859

Sanjay Divakaran, Siling Li, Yang Song, Anna K Krawisz, Brett J Carroll, Eric A Secemsky

引用次数: 0

Pulmonary hypertension-related deaths in patients with acute pulmonary embolism in the United States, 2003 to 2020. 2003 至 2020 年美国急性肺栓塞患者中与肺动脉高压相关的死亡人数。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-08-07 DOI: 10.1177/1358863X241257165

Marco Zuin, Roberto Badagliacca, Eileen Harder, Bridget McGonagle, Christie Greason, Gregory Piazza

{"title":"Pulmonary hypertension-related deaths in patients with acute pulmonary embolism in the United States, 2003 to 2020.","authors":"Marco Zuin, Roberto Badagliacca, Eileen Harder, Bridget McGonagle, Christie Greason, Gregory Piazza","doi":"10.1177/1358863X241257165","DOIUrl":"10.1177/1358863X241257165","url":null,"abstract":"Background: Data regarding the mortality trends in pulmonary embolism (PE)-related mortality in patients with concomitant pulmonary hypertension (PH) are lacking. We assessed the trends in PE-related mortality in patients with concomitant PH in the United States (US) over the past 2 decades and during the first year of the COVID-19 pandemic using data from the Centers for Disease Control and Prevention's (CDC) Wide-ranging ONline Data for Epidemiologic Research (WONDER) dataset.Methods: Mortality data were retrieved from the publicly available CDC WONDER mortality dataset from 2003 to 2020. Age-adjusted mortality rates (AAMRs), per 100,000 population, were assessed using Joinpoint regression modelling and expressed as estimated average annual percentage change (AAPC) with relative 95% CIs and stratified by urbanicity, sex, age, and race/ethnicity.Results: Over the study period, the AAMR for PE/PH-related mortality linearly increased (AAPC: +4.3% [95% CI: 3.7 to 4.9], p < 0.001) without sex differences. The AAMR increase was more pronounced in White individuals (AAPC: +4.8% [95% CI: 4.1 to 5.5], p < 0.001) and in subjects living in rural areas (AAPC: +5.1% [95% CI: 3.8 to 6.4], p < 0.001) compared to those living in urban areas. During the first year of the COVID-19 pandemic there was a significant excess in PE/PH-related mortality among women, older than 65 years and living in rural areas.Conclusions: The rate of PE/PH-related mortality in the US is increasing. Although the early diagnosis of PH in patients with acute PE has become easier with improved diagnostic modalities, the mortality rate of these patients remains high.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"534-542"},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Executive Summary of Standard Operating Procedures for Society for Vascular Medicine (SVM) publications. 血管医学学会 (SVM) 出版物标准操作程序执行摘要。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-08-23 DOI: 10.1177/1358863X241268661

Carlos Mena-Hurtado, Herbert D Aronow, Joshua Beckman, Behnood Bikdeli, Ulf Bronas, Yulanka Castro-Dominguez, Saurav Chatterjee, Islam Y Elgendy, Daniella Kadian-Dodov, Shea Hogan, Sanjum Sethi, Farina Mohamad Yusoff, Debabrata Mukherjee

引用次数: 0

Solving the Rubik's Cube of AAA mortality in Brazil using space-time cube analysis. 利用时空立方体分析解决巴西 AAA 死亡率的魔方问题。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-06-16 DOI: 10.1177/1358863X241254799

Craig S Brown, Oscar Moreno Rocha, Andrea T Obi

引用次数: 0

Geographical disparities in access to surgical treatment and mortality rates from abdominal aortic aneurysms in Brazil: A retrospective longitudinal study. 巴西腹主动脉瘤手术治疗机会和死亡率的地域差异：回顾性纵向研究。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-06-11 DOI: 10.1177/1358863X241253732

Rogério do Lago Franco, Pedro Henrique Iora, Miyoko Massago, Matheus Henrique Arruda Beltrame, Ualid Saleh Hatoum, Vinicius Giacomin, Isadora Martins Borba, Sérgio Quilici Belczak, Catherine Ann Staton, Amanda de Carvalho Dutra, Luciano de Andrade

{"title":"Geographical disparities in access to surgical treatment and mortality rates from abdominal aortic aneurysms in Brazil: A retrospective longitudinal study.","authors":"Rogério do Lago Franco, Pedro Henrique Iora, Miyoko Massago, Matheus Henrique Arruda Beltrame, Ualid Saleh Hatoum, Vinicius Giacomin, Isadora Martins Borba, Sérgio Quilici Belczak, Catherine Ann Staton, Amanda de Carvalho Dutra, Luciano de Andrade","doi":"10.1177/1358863X241253732","DOIUrl":"10.1177/1358863X241253732","url":null,"abstract":"Introduction: Abdominal aortic aneurysm (AAA) is a growing public health problem, and not all patients have access to surgery when needed. This study aimed to analyze spatiotemporal variations in AAA mortality and surgical procedures in Brazilian intermediate geographic regions and explore the impact of different surgical techniques on operative mortality.Methods: A retrospective longitudinal study was conducted to evaluate AAA mortality from 2008 to 2020 using space-time cube (STC) analysis and the emerging hot spot analysis tool through the Getis-Ord Gi* method.Results: There were 34,255 deaths due to AAA, 13,075 surgeries to repair AAA, and a surgical mortality of 14.92%. STC analysis revealed an increase in AAA mortality rates (trend statistic = +1.7693, p = 0.0769) and a significant reduction in AAA surgery rates (trend statistic = -3.8436, p = 0.0001). Analysis of emerging hotspots revealed high AAA mortality rates in the South, Southeast, and Central-West, with a reduction in procedures in São Paulo and Minas Gerais States (Southeast). In the Northeast, there were extensive areas of increasing mortality rates and decreasing procedure rates (cold spots).Conclusion: AAA mortality increased in several regions of the country while surgery rates decreased, demonstrating the need for implementing public health policies to increase the availability of surgical procedures, particularly in less developed regions with limited access to services.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"526-531"},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and safety of aspirin plus clopidogrel versus aspirin alone in ischemic stroke or high-risk transient ischemic attack: A meta-analysis of randomized controlled trials. 阿司匹林加氯吡格雷与单用阿司匹林治疗缺血性中风或高危短暂性脑缺血发作的疗效和安全性：随机对照试验荟萃分析。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-08-20 DOI: 10.1177/1358863X241265335

Mushood Ahmed, Areeba Ahsan, Laveeza Fatima, Jawad Basit, Abdulqadir J Nashwan, Shafaqat Ali, Mohammad Hamza, Iosif Karalis, Raheel Ahmed, Ahmad Alareed, Nkechinyere N Ijioma, M Chadi Alraies

{"title":"Efficacy and safety of aspirin plus clopidogrel versus aspirin alone in ischemic stroke or high-risk transient ischemic attack: A meta-analysis of randomized controlled trials.","authors":"Mushood Ahmed, Areeba Ahsan, Laveeza Fatima, Jawad Basit, Abdulqadir J Nashwan, Shafaqat Ali, Mohammad Hamza, Iosif Karalis, Raheel Ahmed, Ahmad Alareed, Nkechinyere N Ijioma, M Chadi Alraies","doi":"10.1177/1358863X241265335","DOIUrl":"10.1177/1358863X241265335","url":null,"abstract":"Background: Antiplatelet therapy plays an important role in reducing the risk of stroke recurrence in patients with mild ischemic stroke or high-risk transient ischemic attack (TIA). However, data regarding the effectiveness and safety of using aspirin plus clopidogrel in dual antiplatelet therapy (DAPT) compared to aspirin alone in mild ischemic stroke is limited. Methods: PubMed/MEDLINE, Embase, Cochrane Library, and ClinicalTrials.gov were searched for randomized controlled trials (RCTs) that compared DAPT to aspirin alone started within 72 hours in mild ischemic stroke or high-risk TIA. We used a random effects model to pool risk ratios (RRs) along with 95% CIs for clinical outcomes. Results: Four RCTs with 16,547 patients were included in this study. DAPT significantly reduced the risk of recurrent stroke by 26% (RR: 0.74; 95% CI: 0.67-0.83; p < 0.00001), ischemic stroke by 28% (RR: 0.72; 95% CI: 0.65-0.80; p < 0.00001), and major adverse cardiovascular events (MACE) by 24% (RR: 0.76; 95% CI: 0.68-0.84; p < 0.00001) compared to aspirin monotherapy. However, DAPT was associated with a significantly increased risk of moderate or severe bleeding (RR: 1.88; 95% CI: 1.10-3.23; p = 0.02) compared to aspirin alone. No significant differences were observed for hemorrhagic stroke (RR: 1.77; 95% CI: 0.96-3.29; p = 0.07), all-cause mortality (RR: 1.25; 95% CI: 0.87-1.80; p = 0.23), cardiovascular mortality (RR: 1.38; 95% CI: 0.81-2.33; p = 0.23), and myocardial infarction (RR: 1.63; 95% CI: 0.77-3.46; p = 0.20). Conclusion: DAPT involving aspirin plus clopidogrel reduces stroke recurrence and MACE but can lead to an increased risk of moderate or severe bleeding compared to aspirin monotherapy. (PROSPERO ID: CRD42024499310).","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"517-525"},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142009572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of myopathy and hepatotoxicity in patients with cancer receiving statin therapy: Systematic review of randomized controlled trials. 接受他汀类药物治疗的癌症患者发生肌病和肝毒性的风险：随机对照试验的系统回顾

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-06-11 DOI: 10.1177/1358863X241246471

Behnood Bikdeli, Farbod Zahedi Tajrishi, Jean M Connors

引用次数: 0

PCSK9 expression in fibrous cap possesses a marker for rupture in advanced plaque. 纤维帽中 PCSK9 的表达是晚期斑块破裂的标志。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-06-11 DOI: 10.1177/1358863X241252370

Yingying Zhang, Dongwei Dai, Shuang Geng, Chenbin Rong, Rong Zou, Xiaochang Leng, Jianping Xiang, Jianmin Liu, Jing Ding

{"title":"PCSK9 expression in fibrous cap possesses a marker for rupture in advanced plaque.","authors":"Yingying Zhang, Dongwei Dai, Shuang Geng, Chenbin Rong, Rong Zou, Xiaochang Leng, Jianping Xiang, Jianmin Liu, Jing Ding","doi":"10.1177/1358863X241252370","DOIUrl":"10.1177/1358863X241252370","url":null,"abstract":"Background: To date, PCSK9 inhibitors are well known for eliminating cardiac and cerebral artery ischemia events by lowering the serum lipid level. However, the pathophysiological value of in-plaque PCSK9 expression is still unclear.Methods: Advanced plaques removed by carotid endarterectomy were sectioned and stained to identify the PCSK9 expression pattern and its co-expression with rupture-relevant markers. To investigate the correlation of PCSK9 expression with regional blood shear flow, hemodynamic characteristics were analyzed using computational fluid dynamics, and representative parameters were compared between PCSK9 positive and negative staining plaques. To explore this phenomenon in vitro, human aortic vascular smooth muscle cells were used to overexpress and knock down PCSK9. The impacts of PCSK9 modulations on mechanical sensor activity were testified by western blot and immunofluorescence. Real-time polymerase chain reaction was used to evaluate the transcription levels of downstream rupture-prone effectors.Results: PCSK9 distribution in plaque preferred cap and shoulder regions, residing predominantly in smooth muscle actin-positive cells. Cap PCSK9 expression correlated with fibrous cap thickness negatively and co-expressed with MMP-9, both pointing to the direction of plaque rupture. A hemodynamic profile indicated a rupture-prone feature of cap PCSK9 expression. In vitro, overexpression and knockdown of PCSK9 in human aortic vascular smooth muscle cells has positive modulation on mechanical sensor Yes-associated protein 1 (YAP) activity and transcription levels of its downstream rupture-prone effectors. Serial section staining verified in situ colocalization among PCSK9, YAP, and downstream effectors.Conclusions: Cap PCSK9 possesses a biomarker for rupture risk, and its modulation may lead to a novel biomechanical angle for plaque interventions.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"483-495"},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION NOTICE: Circular RNA suppression of vascular smooth muscle apoptosis through the miR-545-3p/CKAP4 axis during abdominal aortic aneurysm formation. 返回通告：在腹主动脉瘤形成过程中，环形 RNA 通过 miR-545-3p/CKAP4 轴抑制血管平滑肌凋亡。

IF 3 3区医学

Vascular Medicine Pub Date : 2024-10-01 Epub Date: 2024-06-16 DOI: 10.1177/1358863X241260141

引用次数: 0