Vascular MedicinePub Date : 2025-07-01DOI: 10.1177/1358863X251349461
Fei Wang, Libing Wei, Ran Liu, Lianrui Guo, Zhu Tong
{"title":"Images in Vascular Medicine: Entrapment of dorsalis pedis artery upon plantar flexion of the foot.","authors":"Fei Wang, Libing Wei, Ran Liu, Lianrui Guo, Zhu Tong","doi":"10.1177/1358863X251349461","DOIUrl":"https://doi.org/10.1177/1358863X251349461","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251349461"},"PeriodicalIF":3.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-06-30DOI: 10.1177/1358863X251346737
Daniel Raskin, Mia Zivkovic, Levester Kirksey, Patrick Ghibes, Abraham Levitin, Aravinda Nanjundappa, Joanna Ghobrial, Sean P Lyden, Jon G Quatromoni, Sameer Gadani, Sasan Partovi
{"title":"Advanced imaging and management of superior vena cava syndrome.","authors":"Daniel Raskin, Mia Zivkovic, Levester Kirksey, Patrick Ghibes, Abraham Levitin, Aravinda Nanjundappa, Joanna Ghobrial, Sean P Lyden, Jon G Quatromoni, Sameer Gadani, Sasan Partovi","doi":"10.1177/1358863X251346737","DOIUrl":"https://doi.org/10.1177/1358863X251346737","url":null,"abstract":"<p><p>Superior vena cava (SVC) syndrome results from stenosis and/or occlusion of the central venous system leading to symptomatology associated with head and neck as well as upper-extremity venous congestion. With the rise in central venous catheter use and increasing cases of malignancy, the incidence of SVC syndrome has steadily increased in recent years. This narrative review explores the clinical presentation of SVC syndrome, alongside its evolving etiologies within modern clinical practice and its pathophysiology. In light of this, advanced imaging modalities and management approaches are discussed based on the extensive institutional experience, detailing the preprocedural imaging techniques, conservative and interventional treatment options, and follow-up imaging protocols.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251346737"},"PeriodicalIF":3.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antithrombotic treatment of cervical artery dissection: A systematic review and meta-analysis.","authors":"Georgios Loufopoulos, Panagiotis Prodromos Papadopoulos, Konstantinos Spanos, Athanasios Giannoukas, Miltiadis Matsagkas, George Kouvelos","doi":"10.1177/1358863X251346736","DOIUrl":"https://doi.org/10.1177/1358863X251346736","url":null,"abstract":"<p><strong>Background: </strong>Though anticoagulation is a well-established treatment for stroke prevention in cervical artery dissection, antiplatelet agents could offer comparable effectiveness and lower bleeding risk. This meta-analysis assesses the incidence of stroke and hemorrhagic events following various antithrombotic treatments.</p><p><strong>Methods: </strong>A systematic search was conducted using PubMed, Scopus, and Cochrane Library databases, including comparative studies involving patients with cervical artery dissection treated with anticoagulants and antiplatelet agents, and was registered in the PROSPERO database. The primary outcomes were stroke and hemorrhagic events. Prespecified random effects subgroup analysis was conducted to examine the impact of different types of anticoagulants and various antiplatelet treatment schemes, indicating the antiplatelet group as the reference for the odds ratio (OR).</p><p><strong>Results: </strong>A total of 22 studies reporting on 5180 patients treated with antiplatelets, vitamin K antagonists (VKAs), and direct oral anticoagulants (DOACs) for prevention of stroke fulfilled the inclusion criteria. The incidence of stroke (OR: 0.86, 95% CI: 0.62-1.20, <i>p</i> = 0.38), intracranial hemorrhage (OR: 0.66, 95% CI: 0.30-1.44, <i>p</i> = 0.30), and extracranial hemorrhage (OR: 0.74, 95% CI: 0.23-2.41, <i>p</i> = 0.62) was not statistically significantly different between the anticoagulant and antiplatelet groups. The comparison of antiplatelets to VKAs (OR: 1.46, 95% CI: 0.79-2.72, <i>p</i> = 0.23) and exclusively aspirin to VKAs (OR: 1.26, 95% CI: 0.48-3.29, <i>p</i> = 0.64) shows nonsignificant differences in terms of stroke. Overall, hemorrhagic events were less frequent in the antiplatelet compared to VKA groups (OR: 0.40, 95% CI: 0.17-0.91, <i>p</i> = 0.03).</p><p><strong>Conclusions: </strong>Anticoagulation demonstrates a comparable incidence of stroke events, intra- and extracranial hemorrhage, and mortality with antiplatelet therapy. (<b>PROSPERO Registration No.: CRD42024535906</b>).</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251346736"},"PeriodicalIF":3.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-06-24DOI: 10.1177/1358863X251346062
Joong Min Park, Ian Beckman, Christopher L Delaney
{"title":"Narrative review of the association between gut microbiota and peripheral artery disease.","authors":"Joong Min Park, Ian Beckman, Christopher L Delaney","doi":"10.1177/1358863X251346062","DOIUrl":"https://doi.org/10.1177/1358863X251346062","url":null,"abstract":"<p><p>It has been posited that the inflammatory process seen in atherosclerosis is underpinned by gut dysbiosis. Dysbiosis refers to alterations in the function, composition, and diversity of the human gut microbiota, all of which are influenced by endogenous and exogenous stimuli. Currently there is limited literature describing the association between gut microbiota and peripheral artery disease (PAD). This review summarizes the evidence surrounding the role of gut microbiota in the initiation of atherosclerosis (through direct infection of atherosclerotic plaque or systemic immune response to bacterial products and metabolites) and how dysbiosis may influence the various treatment modalities for PAD, including medical therapy (pharmacotherapy, lifestyle changes, and supervised exercise training) and surgery (endovascular and open revascularization). In particular, the role of short chain fatty acids (SCFAs), the effects of exercise on SCFA-producing and lactic acid bacteria (LAB) and, consequently, the lack of targeted research into dietary interventions and supplementation are highlighted in this review. This review highlights the potential for gut microbiota as not only a therapeutic target in patients with PAD, but also as a diagnostic and screening tool. It is imperative that the focus of future research is on the potential for personalized treatment which targets the gut microbiota (such as synbiotics, postbiotics, nicotinamide adenine dinucleotide (NAD) supplementation, selective antibiotics, resistance exercise, senolytics, and fecal microbial transplantation [FMT]) to be utilized as adjuncts to already existing treatment options for PAD. This review also highlights the potential role of biobanks and analysis of atherosclerotic plaques in further advancing knowledge and research in this area.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251346062"},"PeriodicalIF":3.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-06-18DOI: 10.1177/1358863X251333672
Arsalan Moinuddin, Craig Paterson, Louise Turner, Keeron Stone, Samuel Je Lucas, Thomas Griffiths, Simon Fryer
{"title":"The effects of acute exposure to prolonged sitting, with and without interruption, on central and peripheral pulse wave velocity: A systematic review and meta-analysis.","authors":"Arsalan Moinuddin, Craig Paterson, Louise Turner, Keeron Stone, Samuel Je Lucas, Thomas Griffiths, Simon Fryer","doi":"10.1177/1358863X251333672","DOIUrl":"https://doi.org/10.1177/1358863X251333672","url":null,"abstract":"<p><strong>Introduction: </strong>Sedentary behavior, specifically an acute bout of prolonged uninterrupted sitting, is associated with heightened cardiovascular disease (CVD) risk, with increased arterial stiffness (AS) being implicated as a principal pathophysiological mechanism. The current systematic review, with meta-analysis, aimed to consolidate the AS response to (1) prolonged uninterrupted sitting and (2) interrupted sitting, as assessed by central and peripheral pulse wave velocity (PWV).</p><p><strong>Methods: </strong>In total, 326 articles were identified, of which 11 and seven met the inclusion criteria for objectives (1) and (2), respectively. Mean differences (MD) and 95% CI were calculated for all trials using a three-level random-effects model, with restricted maximum likelihood (REML) estimation. The amount of heterogeneity was estimated using Cochran's Q and Higgins's <i>I</i><sup>2</sup> tests.</p><p><strong>Results: </strong>(1) Prolonged uninterrupted sitting resulted in a significant increase in carotid-femoral (cf) PWV (MD = 0.184 m/s, 95% CI = 0.098 to 0.270, <i>p</i> < 0.0003). (2) Interrupting bouts of prolonged sitting resulted in a significant increase in cf-PWV (MD = 0.127 m/s, 95% CI = 0.044 to 0.209, <i>p</i> < 0.0026) that was lower compared to the uninterrupted sitting.</p><p><strong>Conclusion: </strong>An acute bout of uninterrupted sitting appears to increase cf-PWV; although interrupting prolonged sitting with brief physical activity is beneficial, it does not fully mitigate the response.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251333672"},"PeriodicalIF":3.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-06-04DOI: 10.1177/1358863X251340633
Saate Shakil, Daniel Chen, Daniel Isquith, Jamie Sapp, Isabella Pommier, Baocheng Chu, Yin Guo, Gador Canton, Niranjan Balu, Chun Yuan, Thomas Hatsukami, Charles Maynard, Xue-Qiao Zhao, Francis Kim
{"title":"Treated HIV infection is not associated with carotid vascular inflammation or plaque progression as assessed by dynamic contrast magnetic resonance imaging.","authors":"Saate Shakil, Daniel Chen, Daniel Isquith, Jamie Sapp, Isabella Pommier, Baocheng Chu, Yin Guo, Gador Canton, Niranjan Balu, Chun Yuan, Thomas Hatsukami, Charles Maynard, Xue-Qiao Zhao, Francis Kim","doi":"10.1177/1358863X251340633","DOIUrl":"https://doi.org/10.1177/1358863X251340633","url":null,"abstract":"<p><strong>Background: </strong>Inflammation and immune dysregulation are thought to drive residual cardiovascular disease risk among persons living with human immunodeficiency virus (HIV) (PLWH) despite effective viral suppression with antiretroviral therapy (ART).</p><p><strong>Methods: </strong>We investigated differences in carotid inflammation and atherosclerosis in a longitudinal cohort of virally suppressed PLWH (<i>N</i> = 50; on stable ART with CD4 > 250 cells/mm<sup>3</sup>, viral load < 200 copies/mL for > 6 months) and HIV-uninfected controls (<i>N</i> = 51) matched for age, sex, hypertension, diabetes, smoking, hyperlipidemia, and family history of premature coronary artery disease (CAD). Participants were ≥ 40 years old at enrollment. Measures of carotid vascular inflammation (<i>K<sup>trans</sup></i>), neovascularization (<i>V<sub>p</sub></i>), and wall thickness were assessed at baseline, 1 year, and change over 1 year by dynamic contrast-enhanced magnetic resonance imaging (MRI).</p><p><strong>Results: </strong>Among 101 participants, 8% were women, 42% had hypertension, 52% had hyperlipidemia, 16% had diabetes, and 48% had a family history of CAD. Both PLWH and control participants demonstrated a reduction in systolic and diastolic blood pressures and total cholesterol over 1 year; however, the difference was not significant by HIV status. PLWH had a significant reduction in triglycerides compared with controls (-48.8 vs 12.8 mg/dL, <i>p</i> = 0.026). HIV was not associated with baseline, follow up, or change in markers of systemic inflammation assessed by plasma cytokines, nor vascular inflammation as assessed by <i>K<sup>trans</sup></i>, <i>V<sub>p</sub></i>, carotid wall thickness, or percent wall volume (a measure of plaque burden).</p><p><strong>Conclusion: </strong>In contrast to other studies of treated and virally suppressed PLWH, HIV infection was not associated with carotid inflammation or plaque in our hypothesis-generating study.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251340633"},"PeriodicalIF":3.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-06-01Epub Date: 2025-03-13DOI: 10.1177/1358863X251315071
Smaragda Lampridou, Tania Domun, Javiera Rosenberg, Rachael Lear, Alun Huw Davies, Mary Wells, Gaby Judah
{"title":"Multicomponent interventions designed to support adherence to guideline-recommended therapy in patients with peripheral artery disease: A scoping review.","authors":"Smaragda Lampridou, Tania Domun, Javiera Rosenberg, Rachael Lear, Alun Huw Davies, Mary Wells, Gaby Judah","doi":"10.1177/1358863X251315071","DOIUrl":"10.1177/1358863X251315071","url":null,"abstract":"<p><p>Adherence to guideline-recommended therapies for peripheral artery disease (PAD), including pharmacotherapy (antiplatelet, lipid-lowering, and antihypertensive agents) and lifestyle modifications (smoking cessation, diet, weight management, and physical activity) remains low. Though single-component interventions targeting smoking cessation, exercise, or medication adherence show some efficacy, comprehensive multicomponent interventions are vital for addressing the complexity of PAD management. This review systematically synthesized multicomponent interventions for patients with PAD. A systematic search was conducted in Embase, MEDLINE, Cochrane Library, APA PsycINFO, CINAHL, Web of Science Core Collection, ProQuest, and Google Scholar to identify primary research describing multicomponent interventions supporting PAD treatment adherence, published between 2007 and 2024. A narrative synthesis was reported using the Template for Intervention Description and Replication (TIDieR) checklist and the behavioral change techniques (BCT) taxonomy. Out of 15 studies (2462 patients, 60.4% men) included in this review, only two addressed all guideline-recommended treatment aspects. Key intervention components included structured exercise (12/15) and education programs (10/15). Most interventions were delivered by multidisciplinary teams in hospital settings over 3 months. Only one study employed behavioral theory in its development, and most interventions (13/15) focused on the BCT 'instructions on how to perform a behavior' rather than diverse BCTs. No interventions significantly increased adherence to all PAD therapies. Few studies measured the intervention's impact on adherence, making it difficult to determine effective intervention characteristics. Most interventions lacked behavioral science approaches and were not designed to address specific adherence determinants. Future interventions should incorporate these elements to effectively address patients' needs. <b>Open Science Framework Registry ID: osf.io/7xqzj</b>.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"343-352"},"PeriodicalIF":3.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-06-01Epub Date: 2025-05-14DOI: 10.1177/1358863X251322177
Kasthuri Nair, Brandi M Mize, Mia S White, Tabia Henry Akintobi, Rachel E Patzer, Shipra Arya, Olamide Alabi
{"title":"Reporting of race, ethnicity, and gender in lower-extremity peripheral artery disease randomized controlled trials.","authors":"Kasthuri Nair, Brandi M Mize, Mia S White, Tabia Henry Akintobi, Rachel E Patzer, Shipra Arya, Olamide Alabi","doi":"10.1177/1358863X251322177","DOIUrl":"10.1177/1358863X251322177","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"315-317"},"PeriodicalIF":3.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-06-01Epub Date: 2025-03-03DOI: 10.1177/1358863X251322182
Georgia R Parsons, Gomathy Parvathinathan, Ali Etemadi, Sai Liu, Elsie Ross, W Schuyler Jones, Margaret R Stedman, Tara I Chang
{"title":"Identifying peripheral artery disease in persons with and without chronic kidney disease from electronic health records.","authors":"Georgia R Parsons, Gomathy Parvathinathan, Ali Etemadi, Sai Liu, Elsie Ross, W Schuyler Jones, Margaret R Stedman, Tara I Chang","doi":"10.1177/1358863X251322182","DOIUrl":"10.1177/1358863X251322182","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"312-314"},"PeriodicalIF":3.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-06-01Epub Date: 2025-05-09DOI: 10.1177/1358863X251320917
Natalie S Evans, Alexandra L Solomon, Elizabeth V Ratchford
{"title":"Vascular Disease Patient Information Page: Peripheral artery disease - 2025 update.","authors":"Natalie S Evans, Alexandra L Solomon, Elizabeth V Ratchford","doi":"10.1177/1358863X251320917","DOIUrl":"10.1177/1358863X251320917","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"384-388"},"PeriodicalIF":3.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}