Veterinary dermatology最新文献

{"title":"Comments on the Antimicrobial Use Guidelines for Canine Pyoderma by the International Society for Companion Animal Infectious Diseases.","authors":"Tomoki Motegi","doi":"10.1111/vde.70018","DOIUrl":"10.1111/vde.70018","url":null,"abstract":"","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"529-530"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID).","authors":"Anette Loeffler, Christine L Cain, Lluís Ferrer, Koji Nishifuji, Katarina Varjonen, Mark G Papich, Luca Guardabassi, Siân M Frosini, Emi N Barker, Scott J Weese","doi":"10.1111/vde.13365","DOIUrl":"10.1111/vde.13365","url":null,"abstract":"<p><strong>Background: </strong>Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing.</p><p><strong>Objectives: </strong>To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin-resistant staphylococci. Guidance on diagnosing surface, superficial and deep pyoderma, and their underlying primary causes is included. Recommendations aim to optimise treatment outcomes while promoting responsible antimicrobial use.</p><p><strong>Materials and methods: </strong>Evidence was gathered from a systematic literature review of English-language treatment studies for canine pyoderma up to 23/12/2023. Quality was assessed using SORT criteria and combined with authors' consensus evaluation. Recommendations were voted on in an iterative process, followed by a Delphi-style feedback process before final agreement by the authors.</p><p><strong>Results: </strong>Cytology should be performed in all cases before antimicrobials are used. Topical antimicrobial therapy alone is the treatment-of-choice for surface and superficial pyodermas. Systemic antimicrobials should be reserved for deep pyoderma and for superficial pyoderma when topical therapy is not effective. Systemic therapy, with adjunctive topical treatment, is initially provided for 2 weeks in superficial and 3 weeks in deep pyoderma, followed by re-examination to assess progress and manage primary causes. First-choice drugs have expected efficacy against the majority of meticillin-susceptible Staphylococcus pseudintermedius; for all others, laboratory testing should confirm susceptibility and exclude suitability of safer alternatives. As culture and susceptibility testing are essential for rationalising systemic therapy, laboratories and practices should price them reasonably to encourage use. Proactive topical therapy using antiseptics may help prevent recurrences.</p><p><strong>Conclusions and clinical relevance: </strong>The accessibility of the skin offers excellent, achievable opportunities for antimicrobial stewardship.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"552-565"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An open-label pilot study on an adsorbent mousse containing adelmidrol in client-owned cats with feline atopic skin syndrome and associated seborrhoea.","authors":"Chiara Noli, Maria Federica Della Valle, Giada Morelli, Carlo Schievano","doi":"10.1111/vde.13346","DOIUrl":"10.1111/vde.13346","url":null,"abstract":"<p><strong>Background: </strong>Besides pruritus and skin lesions, cats with feline atopic skin syndrome (FASS) may have seborrhoea.</p><p><strong>Hypothesis/objectives: </strong>The aim of this pilot study was to investigate whether an adsorbent mousse containing tapioca starch, adelmidrol and a nonpharmacological antimicrobial complex could decrease FASS-associated seborrhoea in cats.</p><p><strong>Animals: </strong>Seven client-owned cats with FASS were included based on the presence of seborrhoea and pruritus (>4 cm on the validated feline pruritus Visual Analog Scale [VAScat]), regardless of the concomitant administration of antiallergic drugs, provided that they were used for ≥1 month before study entry and maintained unchanged.</p><p><strong>Materials and methods: </strong>Cats were evaluated weekly by owners and every other week by veterinary surgeons for 2 (optionally 4) weeks using a four-item skin seborrhoeic index (SSI). The VAScat and the scoring feline allergic dermatitis (SCORFAD) index also were used to assess pruritus and skin lesion severity, respectively. The Wilcoxon signed-rank test was used for pre- versus post-treatment comparisons.</p><p><strong>Results: </strong>At the end of Week 2, the mean score value for SSI was significantly decreased (p = 0.016). At the same time point, the mean severity of pruritus and the mean SCORFAD index value had also decreased (p = 0.016). Moreover, 86% of the investigators were 'satisfied' or 'very satisfied' with the tested mousse. Four cats continued the study up to Week 4 and showed a further, albeit nonsignificant, decrease in all evaluated scores.</p><p><strong>Conclusions and clinical relevance: </strong>These preliminary findings have promising implications for clinical practice in cats with FASS-associated seborrhoea and are worth further investigation.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"638-646"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of saline-soaked bacterial culture swabs increases bacterial recovery in dogs with superficial bacterial folliculitis.","authors":"Jason B Pieper, Payton VanDusseldorp, Amanda J Kreuder, Darren J Berger","doi":"10.1111/vde.13355","DOIUrl":"10.1111/vde.13355","url":null,"abstract":"<p><strong>Background: </strong>Canine superficial bacterial folliculitis (SBF) is a common recurrent condition with a growing requirement for culture and susceptibility as a consequence of increased antimicrobial resistance and antimicrobial stewardship. Different opinions persist about the ideal technique for culture sample acquisition, which varies with lesion characteristics.</p><p><strong>Objective: </strong>To determine if a difference exists in the recovered quantity of bacteria acquired when sampling nonexudative clinical lesions of SBF (crusts and epidermal collarettes) between a dry culture swab and a saline-moistened culture swab.</p><p><strong>Animals: </strong>Nine dogs with crusts or epidermal collarettes and cytological findings consistent with SBF were recruited.</p><p><strong>Materials and methods: </strong>Each clinical lesion was divided into two halves. One half of the lesion was sampled with a dry cotton sterile swab, while the other half was sampled with a sterile swab saturated with sterile saline. Each lesion was sampled with the culture swab by rolling it over the corresponding half four times. Aerobic quantitative cultures were then performed to determine the number of Staphylococcus-type colonies present.</p><p><strong>Results: </strong>A total of 19 lesions (13 crusts and six epidermal collarettes) were evaluated. Dry culture swab identified a mean staphylococcal bacterial count of 3.83 Log₁₀ colony-forming units (cfu)/mL (standard deviation [SD] = 0.70). The saline-soaked culture swab revealed a median bacterial count of 4.41 Log₁₀ cfu/mL (SD = 0.77). There was a statistically significant difference between the sample collection methods (p = 0.002).</p><p><strong>Conclusions and clinical relevance: </strong>Sterile saline-soaked swabs are more likely than dry swabs to result in increased recovery of bacteria from nonexudative lesions.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"621-629"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-term administration of oclacitinib with concomitant medications in canine epitheliotropic lymphoma: A retrospective study of eight dogs.","authors":"Yuta Baba, Tomo Asakura, Saki Obayashi, Miyuki Yamada, Motoki Otsuka, Shinya Morikawa, Angeline Teh, Ikki Mitsui, Takafumi Osumi","doi":"10.1111/vde.13366","DOIUrl":"10.1111/vde.13366","url":null,"abstract":"<p><strong>Background: </strong>Canine cutaneous epitheliotropic lymphoma (CEL) is a rare neoplastic disease with poor prognosis. Oclacitinib, a Janus kinase inhibitor primarily used to treat allergic and atopic dermatitis in dogs, may also cause other skin diseases.</p><p><strong>Objectives: </strong>This study aimed to evaluate the efficacy of oclacitinib in the treatment of canine cutaneous lymphoma.</p><p><strong>Animals: </strong>Eight client-owned dogs with CEL were included in the study.</p><p><strong>Materials and methods: </strong>The dogs were administered oclacitinib. This study examined the immunological characteristics, time to treatment initiation, dosage, cutaneous lesions and pruritus, adverse events, survival time and prior oclacitinib use.</p><p><strong>Results: </strong>Only one of the eight dogs (12.5%) showed symptomatic improvement after oclacitinib treatment, with no clinical improvement observed in the other cases. Improvement in pruritus was noted in only one dog. Adverse events included mild leucopenia in one dog, which did not significantly affect prognosis. The median survival time after diagnosis was 228.5 days.</p><p><strong>Conclusions and clinical relevance: </strong>These results suggest that oral oclacitinib has limited efficacy in the treatment of canine CEL. Larger prospective studies are recommended to further investigate the optimal dose, treatment duration and potential combination therapies involving oclacitinib.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"660-667"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter From Dr. Motegi on the Antimicrobial Use Guidelines for Canine Pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID).","authors":"Anette Loeffler","doi":"10.1111/vde.70019","DOIUrl":"10.1111/vde.70019","url":null,"abstract":"","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"531-532"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First report of indolent cutaneous T-cell lymphoma in a fennec fox (Vulpes zerda).","authors":"Kristen L Shekelle, Alan R Glassman, Kay A Backues, Jennifer J Kilburn, Desirae A Foust-Wheatcraft, Lauren Wood Stranahan","doi":"10.1111/vde.13351","DOIUrl":"10.1111/vde.13351","url":null,"abstract":"<p><p>A 10-year-old fennec fox (Vulpes zerda) was presented for multifocal regions of chronic alopecia and crusting. Cutaneous lymphocytosis was diagnosed through histopathological examination and immunohistochemical investigation. Clonal rearrangement of the T-cell receptor gamma locus supports that lymphocytosis in this case was an indolent lymphoma.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"707-711"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Honouring the legacy of Professor Carlos Eduardo Larsson: A pioneer in veterinary dermatology in Brazil.","authors":"Aline E Santana, Ana C Balda","doi":"10.1111/vde.13350","DOIUrl":"10.1111/vde.13350","url":null,"abstract":"","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"527-528"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of microbial contamination of commercial Romanowsky stain variant solutions used in veterinary clinics.","authors":"Minji Cho, Seulgi Bae","doi":"10.1111/vde.13362","DOIUrl":"10.1111/vde.13362","url":null,"abstract":"<p><strong>Background: </strong>Diff-Quik (DQ) staining is widely used in clinical practice for its ease of use and rapid results. However, its potential contamination remains a concern.</p><p><strong>Hypothesis/objectives: </strong>This study aimed to investigate DQ solution contamination in veterinary hospitals and identify factors affecting it through a questionnaire on stain usage practices.</p><p><strong>Materials and methods: </strong>A survey was conducted to assess the use of DQ staining in local animal clinics. Samples of DQ solution II collected from each hospital participating in the survey were cultured and analysed microscopically for contamination.</p><p><strong>Results: </strong>A total of 67 DQ stain samples were collected from veterinary hospitals, of which 10 (14.92%) were found to be contaminated with pathogens. Bacterial cultures were positive in six of the samples (8.95%); four were contaminated with Staphylococcus pseudintermedius, one with Stenotrophomonas maltophilia and one with Bacillus haynesii. Malassezia pachydermatis was found in the remaining contaminated samples (n = 4, 5.97%). Statistical analysis revealed that the significant factors associated with DQ stain contamination were the use of a dropper, direct immersion of slides in the dye, average weekly usage and periodic replacement of the solution (p < 0.05).</p><p><strong>Conclusions and clinical relevance: </strong>This study confirms DQ solution contamination in general veterinary practice. To minimise contamination risk, using a dropper for stain application instead of direct specimen immersion in the stain is recommended. Furthermore, in hospitals where DQ solutions are frequently employed, the stain should be periodically replaced or examined under a microscope.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"613-620"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Equine Urticaria Activity Score for the assessment of chronic recurrent urticaria in horses.","authors":"Katharina Birkmann, Nina Waldern, Simone Jucker, Katharina Balaschitsch, Yury Zablotski, Antonia Fettelschoss-Gabriel","doi":"10.1111/vde.13358","DOIUrl":"10.1111/vde.13358","url":null,"abstract":"<p><strong>Background: </strong>Recurrent urticaria is common in horses. The pathophysiology is poorly understood and treatment options are limited. Often, only glucocorticoids are effective for controlling clinical signs, albeit with potential adverse effects. Studies investigating new treatments need a validated objective scoring system for the grading of skin lesions to assess response.</p><p><strong>Hypothesis/objectives: </strong>The aims were to investigate inter- and intraobserver reliability of the Equine Urticaria Activity Score (EqUAS) for the grading of skin lesions in horses with recurrent urticaria, and to examine agreement between experienced and inexperienced observers.</p><p><strong>Animals: </strong>Forty privately owned horses enrolled in a therapeutic clinical trial.</p><p><strong>Materials and methods: </strong>Ten standardised photographs of both sides of the body of each horse were used to create 40 individual datasets. Five masked observers graded the photographs according to the EqUAS for calculation of interobserver reliability. Intraobserver reliability was calculated from two observers each grading the photographs twice. Scores were evaluated for reliability with Pearson's correlation (r) and for agreement with the intraclass correlation coefficient (ICC).</p><p><strong>Results: </strong>Interobserver reliability was excellent with r = 0.9036-0.9600 (p < 0.0001). Intraobserver reliability and agreement also were excellent with r = 0.98 for each observer (p < 0.0001) and ICC = 0.945. Correlation and agreement between experienced and inexperienced observers were excellent (r = 0.9615 [p < 0.0001] and ICC = 0.941).</p><p><strong>Conclusions and clinical relevance: </strong>The EqUAS showed excellent intra- and interobserver reliability for the evaluation of skin lesions of horses with chronic recurrent urticaria. It can be a useful tool in clinical studies.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"630-637"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}