Veterinarni Medicina最新文献_第8页

Evaluating the indicators of a heart rate variability analysis in dogs using Poincaré plots. 利用波恩卡雷图评估狗的心率变异性分析指标。

IF 0.7 4区农林科学

Veterinarni Medicina Pub Date : 2024-02-27 eCollection Date: 2024-02-01 DOI: 10.17221/49/2023-VETMED

Taichi Kimura, Shunsuke Shimamura, Hiroshi Sakaya, Tetsuya Hayashi, Azusa Umemoto, Kosei Sakai, Masahiro Yamasaki, Tetsuya Hasegawa, Terumasa Shimada

{"title":"Evaluating the indicators of a heart rate variability analysis in dogs using Poincaré plots.","authors":"Taichi Kimura, Shunsuke Shimamura, Hiroshi Sakaya, Tetsuya Hayashi, Azusa Umemoto, Kosei Sakai, Masahiro Yamasaki, Tetsuya Hasegawa, Terumasa Shimada","doi":"10.17221/49/2023-VETMED","DOIUrl":"10.17221/49/2023-VETMED","url":null,"abstract":"Heart rate variability analyses using Poincaré plots can be useful for evaluating the autonomic nervous system function. However, the interpretation of the quantitative indicators of Poincaré plots remains controversial. Thus, few studies have verified the effectiveness of the quantitative indicators in veterinary medicine. This study aimed to verify the reliability of Poincaré plot indicators using pharmacological models in dogs. Four healthy beagles were used in this study. Each dog was treated with propranolol, atropine, and propranolol-atropine to block the sympathetic, parasympathetic, and sympathetic-parasympathetic functions, respectively. The quantitative indicators of the Poincaré plots were calculated based on data from 300 electrocardiogram beats collected before and after the administration of each drug and statistically analysed. The quantitative indicators of the Poincaré plots, such as the standard deviation perpendicular to the major axis (SD1), standard deviation along the major axis (SD2), and SD1 × SD2, significantly decreased after the drug administration in both the parasympathetic and sympathetic-parasympathetic blockade models. However, no significant differences were observed in SD1/SD2 between the groups. The Poincaré plots reflected the changes in the autonomic nervous system of dogs. In dogs, SD1, SD2, and SD1 × SD2 can detect a state in which parasympathetic nerve activity is suppressed.","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 2","pages":"42-51"},"PeriodicalIF":0.7,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10966429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacokinetics of praziquantel and its metabolites in grass carp (Ctenopharyngodon idella) following the oral administration of a single bolus. 草鱼（Ctenopharyngodon idella）口服吡喹酮及其代谢物的药代动力学。

IF 0.6 4区农林科学

Veterinarni Medicina Pub Date : 2024-02-27 eCollection Date: 2024-02-01 DOI: 10.17221/109/2023-VETMED

Radka Dobsikova, Jana Blahova, Petr Marsalek, Veronika Doubkova, Eliska Zuskova, Josef Velisek

{"title":"Pharmacokinetics of praziquantel and its metabolites in grass carp (Ctenopharyngodon idella) following the oral administration of a single bolus.","authors":"Radka Dobsikova, Jana Blahova, Petr Marsalek, Veronika Doubkova, Eliska Zuskova, Josef Velisek","doi":"10.17221/109/2023-VETMED","DOIUrl":"10.17221/109/2023-VETMED","url":null,"abstract":"The study aimed to evaluate and compare the routes and rates of the depletion of the antiparasitic praziquantel (PZQ), a derivative of pyrazinoisoquinoline, following its oral administration in grass carp (Ctenopharyngodon idella). We focused on the depletion of PZQ and its major metabolites - cis-hydroxy praziquantel (CPZQ) and trans-hydroxy praziquantel (TPZQ), in water, the plasma, hepatopancreas, kidney, muscle, and skin, following a single oral administration of PZQ in a concentration of 50 mg/kg. Fish were sampled before the drug administration and then eight times in the course of the 30-day-long experiment. Our results indicate the rapid absorption and elimination of PZQ and its metabolites in all the analysed matrices. The most PZQ-burdened tissue was the hepatopancreas, the gill and the skin. In all the samples, the concentration of the drug and its metabolites consistently declined over time. The residue of the parent compound was detected for the longest time in all the tissues. During the study, a significant (P < 0.01) correlation was found within the concentration of PZQ, CPZQ, and TPZQ in the water and all the biological matrices. It was also found that the PZQ residue was not detected below the maximum residue levels (i.e., 20 μg/kg) until 16 days after exposure in the muscle and skin.","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 2","pages":"52-60"},"PeriodicalIF":0.6,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10966426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of the T1640C RYR1 mutation indicating malignant hyperthermia in dogs. 检测表明狗患有恶性高热的 T1640C RYR1 突变。

IF 0.7 4区农林科学

Veterinarni Medicina Pub Date : 2023-11-29 eCollection Date: 2023-11-01 DOI: 10.17221/46/2023-VETMED

Jana Haluskova, Beata Holeckova, Lenka Kokulova, Martina Galdikova, Jaroslav Bucan, Viera Schwarzbacherova, Silvia Sedlakova

{"title":"Detection of the T1640C RYR1 mutation indicating malignant hyperthermia in dogs.","authors":"Jana Haluskova, Beata Holeckova, Lenka Kokulova, Martina Galdikova, Jaroslav Bucan, Viera Schwarzbacherova, Silvia Sedlakova","doi":"10.17221/46/2023-VETMED","DOIUrl":"10.17221/46/2023-VETMED","url":null,"abstract":"Malignant hyperthermia (MH) is a clinical syndrome exhibiting elevation of expired carbon dioxide, hyperthermia, muscle rigidity, rhabdomyolysis, acidosis and hyperkalaemia, as well as cardiac dysrhythmia and renal failure. The syndrome manifests itself as a response to anaesthetic agents, such as e.g., halothane, desflurane, and succinylcholine. Depending on the animal species, MH is characterised by autosomal dominant or recessive inheritance, and so far two genes have been identified whose mutations can be linked to MH: RYR1 and CACNA1S. In different species, various mutations of the RYR1 gene have been described which may underlie MH. One of these mutations in dogs is T1640C, which results in the substitution of alanine for valine of the amino acid 547 (V547A) in the RYR1 protein. In our work, we aimed to investigate MH at the DNA level by identifying the T1640C mutation in a group of 50 dogs. For this purpose we used the PCR-RFLP technique, and in six dogs also direct sequencing of PCR products and subsequent comparison of their sequences with the RYR1 gene sequence in an online database. The results of our study show that none of the dogs analysed had any mutant allele of the RYR1 gene, indicating that none should be affected by MH.","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"68 11","pages":"428-434"},"PeriodicalIF":0.7,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10755811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139075074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predominance of Acinetobacter pseudolwoffii among Acinetobacter species in domestic animals in the Czech Republic. 捷克共和国家畜中的假溶血性醋酸杆菌占优势。

IF 0.7 4区农林科学

Veterinarni Medicina Pub Date : 2023-11-29 eCollection Date: 2023-11-01 DOI: 10.17221/65/2023-VETMED

Vladimir Sladecek, David Senk, Petr Stolar, Jaroslav Bzdil, Ondrej Holy

{"title":"Predominance of Acinetobacter pseudolwoffii among Acinetobacter species in domestic animals in the Czech Republic.","authors":"Vladimir Sladecek, David Senk, Petr Stolar, Jaroslav Bzdil, Ondrej Holy","doi":"10.17221/65/2023-VETMED","DOIUrl":"10.17221/65/2023-VETMED","url":null,"abstract":"The aim of this study was to map the spectrum of microorganisms belonging to the genus Acinetobacter in domestic animals with a specific focus on the prevalence of Acinetobacter pseudolwoffii. Additionally, the susceptibility of isolates to antimicrobial agents was determined. In the period from January 1, 2014, to August 31, 2015, a total of 9 544 samples originating from gross lesions and pathological processes of animals exhibiting clinical symptoms of the disease were examined across 41 districts in the Czech Republic. The examinations were carried out using culture methods involving meat-peptone blood agar and Endo agar under aerobic conditions at a temperature of 37 ± 1 °C for 18-24 hours. Isolates were confirmed using molecular phenotypic method MALDI-TOF MS with the MBT Compass Library Revision L 2020 covering 3 239 species/entries (9 607 MSP) from Bruker Daltonics company. Out of the 108 isolates (prevalence 1.13%), 14 species of Acinetobacter spp. were identified, with 5 isolates remaining unclassified as species. A. pseudolwoffii was the predominant species isolated in 25 cases (prevalence 0.26%). Antimicrobial susceptibility was determined for 12 antimicrobials by the disc diffusion method, with A. pseudolwoffii isolates exhibiting the lowest susceptibility to ceftazidime (32%) and co-trimoxazole (60%).","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"68 11","pages":"419-427"},"PeriodicalIF":0.7,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10755813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139072573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Updating of epidemiological and pathological features of Marek's disease in laying hens and broilers. 更新蛋鸡和肉鸡马立克氏病的流行病学和病理学特征。

IF 0.7 4区农林科学

Veterinarni Medicina Pub Date : 2023-11-27 eCollection Date: 2023-11-01 DOI: 10.17221/75/2023-VETMED

Mourad Zeghdoudi, Merdaci Latifa, Madi Seloua, Sadeddine Rima, Tahri Mardja, Aoun Leila

{"title":"Updating of epidemiological and pathological features of Marek's disease in laying hens and broilers.","authors":"Mourad Zeghdoudi, Merdaci Latifa, Madi Seloua, Sadeddine Rima, Tahri Mardja, Aoun Leila","doi":"10.17221/75/2023-VETMED","DOIUrl":"10.17221/75/2023-VETMED","url":null,"abstract":"Marek's disease (MD) is a huge problem for researchers due to the significant losses in bird flocks, but more importantly, the virus's mutagenic potential. The purpose of this study was to describe non-classical gross lesions observed in broilers and laying hens that suggest the disease emergence and re-emergence. The survey was conducted on 10 broiler and 4 laying hen flocks. All of the dead birds were necropsied in order to obtain a comprehensive diagnosis of lesions, analysing both macroscopic and microscopic alterations. Marek's disease occurred in 80% of cases in broilers and 100% of cases in layer hens. The disease struck 26-day-old broilers and hens at 2 weeks of age, causing a total mortality of 6% and 15%, respectively. There were no clinical indications of the classical neurological form of the disease in either rearing type, and tumour lesions were mostly detected in the liver, spleen, and ovarian follicles in layers, and in the proventriculus in broilers. These findings demonstrated that MD is widespread and that its resurgence is primarily manifested in visceral rather than neurological manifestations. Despite MD immunization, biosecurity remains critical.","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"68 11","pages":"443-448"},"PeriodicalIF":0.7,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10755812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139075076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gallbladder atrophy associated with pancreatitis: Clinical and advanced imaging diagnosis in a dog. 胆囊萎缩伴有胰腺炎：一只狗的临床和高级影像诊断

IF 0.6 4区农林科学

Veterinarni Medicina Pub Date : 2023-11-20 eCollection Date: 2023-11-01 DOI: 10.17221/76/2023-VETMED

Donghyun Han, Dong-In Jung

{"title":"Gallbladder atrophy associated with pancreatitis: Clinical and advanced imaging diagnosis in a dog.","authors":"Donghyun Han, Dong-In Jung","doi":"10.17221/76/2023-VETMED","DOIUrl":"10.17221/76/2023-VETMED","url":null,"abstract":"Gallbladder atrophy (GBA) is characterised by a reduction in the size and volume of the gallbladder. In human medicine, it is well-established that GBA frequently occurs together with pathologies affecting the gallbladder and pancreas. However, to the best of our knowledge, there is currently a dearth of reported cases of GBA in dogs within the veterinary field. In this study, we present a case report of GBA in a 7-year-old Yorkshire Terrier. The diagnosis of GBA was confirmed using abdominal ultrasonography and advanced imaging techniques, including computed tomography, which were performed over a 4-year period. The patient initially presented with predominantly gastrointestinal symptoms, which were subsequently diagnosed and treated as pancreatitis. Concurrently, a gallbladder nodule and an anomalous structure suspected to be cholelithiasis were identified. However, during the 4-year follow-up, the gallbladder structure regressed, leaving only the presence of the gallbladder nodule. Notably, cholecystectomy was not performed, and apart from pancreatitis-related symptoms, the patient did not show any gallbladder-related problems throughout the spontaneous atrophic process. Based on these findings, we propose that the observed GBA was likely induced by cholecystitis associated with pancreatitis. This case underscores the significance of considering GBA as a potential diagnosis in canine patients presenting with pancreatitis and gastrointestinal symptoms. Furthermore, it highlights the value of comprehensive diagnostic imaging in accurately determining the underlying cause of these symptoms.","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"68 11","pages":"435-442"},"PeriodicalIF":0.6,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10755810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139075075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spinal cord haemangiosarcoma in one dog - Case report 犬脊髓血管肉瘤1例报告

4区农林科学

Veterinarni Medicina Pub Date : 2023-10-31 DOI: 10.17221/60/2023-vetmed

M Kuricova, J Fuchs, T Liptak, F Korim, N Surin Hudakova, B Bhattarai, Z Kerekes, V Revajova

引用次数: 0

Effect of novel carboxymethyl cellulose-based dressings on acute wound healing dynamics 新型羧甲基纤维素敷料对急性伤口愈合动力学的影响

4区农林科学

Veterinarni Medicina Pub Date : 2023-10-31 DOI: 10.17221/89/2023-vetmed

A Kruzicova, M Chalupova, G Kuzminova, T Parak, J Klusakova, T Sopuch, P Suchy

引用次数: 0

Lactobacillus sp. participated in the adaptation of Rongchang piglets to cold stress 乳酸菌参与了荣昌仔猪对冷应激的适应

4区农林科学

Veterinarni Medicina Pub Date : 2023-10-24 DOI: 10.17221/54/2023-vetmed

J Chai, X Long, P Wu, J Wang, X Wu, Z Tu, M Wei, Z Guo, T Zhang, L Chen

{"title":"Lactobacillus sp. participated in the adaptation of Rongchang piglets to cold stress","authors":"J Chai, X Long, P Wu, J Wang, X Wu, Z Tu, M Wei, Z Guo, T Zhang, L Chen","doi":"10.17221/54/2023-vetmed","DOIUrl":"https://doi.org/10.17221/54/2023-vetmed","url":null,"abstract":"Rongchang piglets were easily induced toÂ cold stress and diarrhoea inÂ the winter when raised inÂ an open hog house. However, they also gradually recovered under mid-cold stress. Other studies have suggested gut microbiome might beÂ involved inÂ the host energy metabolism toÂ relieve stress. ToÂ study how toÂ adapt Rongchang piglets toÂ cold stress byÂ gut microbiome, thirty Rongchang piglets were randomly divided into aÂ mild cold stress group and aÂ control group for 30Â consecutive days. The findings revealed that the piglets had low growth performance and aÂ high diarrhoea rate and mortality rate during the first half ofÂ the cold treatment, but subsequently stabilised. The level ofÂ cortisol (COR) also displayed aÂ similar trend. InÂ the mild cold stress group, the relative abundance ofÂ Muribaculaceae significantly increased onÂ dayÂ 15, and the predominant bacterial onÂ dayÂ 30 was Lactobacillus sp. Our results indicated that the Rongchang piglet’s production performance and health were impaired atÂ the start ofÂ the mild cold stress. However, asÂ time passed, the body could progressively adapt toÂ the low temperature, and Lactobacillus sp. participated inÂ this process. This study provides new insight into how toÂ alleviate health damage caused byÂ cold stress.","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"24 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135268106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seroprevalence and haemato-biochemical effects of bovine leucosis in buffalo, Punjab, Pakistan 巴基斯坦旁遮普省水牛白血病的血清患病率和血液生化效应

4区农林科学

Veterinarni Medicina Pub Date : 2023-10-24 DOI: 10.17221/57/2023-vetmed

A Rahman, M Kashif, A Nasir, S Ehtisham-ul-Haque, H Ullah, A Sikandar, I Ahmed, AU Rehman, MA Saeed, MW Nazar, M Rizwan, S Saher, A Abbas

{"title":"Seroprevalence and haemato-biochemical effects of bovine leucosis in buffalo, Punjab, Pakistan","authors":"A Rahman, M Kashif, A Nasir, S Ehtisham-ul-Haque, H Ullah, A Sikandar, I Ahmed, AU Rehman, MA Saeed, MW Nazar, M Rizwan, S Saher, A Abbas","doi":"10.17221/57/2023-vetmed","DOIUrl":"https://doi.org/10.17221/57/2023-vetmed","url":null,"abstract":"Enzootic bovine leucosis isÂ caused byÂ bovine leukaemia virus (BLV), aÂ Deltaretrovirus belonging toÂ the family Retroviridae. BLV causes huge economic losses toÂ the dairy industry inÂ the form ofÂ decreased milk production, premature culling, and poor reproductive performance ofÂ the animals. The aim ofÂ the present study was toÂ determine the seroprevalence ofÂ BLV infection inÂ buffalo inÂ two districts ofÂ Punjab, Pakistan. AÂ total ofÂ 384 samples were collected and analysed using aÂ commercial indirect enzyme-linked immunosorbent assay (ELISA) toÂ investigate the seroprevalence ofÂ BLV through the detection ofÂ the anti-BLV gp51 antibody. AÂ predesigned data questionnaire proforma was employed toÂ find out the association ofÂ risk factors with disease. Overall, 18.2% ofÂ buffaloes were seropositive for BLV inÂ the study population. The results revealed aÂ significant association (PÂ <Â 0.05) ofÂ age with BLV infection. Furthermore, milk yield and pregnancy had aÂ significant association with the seroprevalence ofÂ BLV infection inÂ buffalo whereas noÂ significant association was found with sex, breeding, and health status. Biochemical and oxidative stress markers revealed aÂ significant decrease inÂ liver enzymes alanine transaminase (ALT) and aspartate transaminase (AST), glutathione peroxidase (GPX), and superoxide dismutase (SOD) inÂ seropositive animals asÂ compared toÂ healthy animals. ItÂ is concluded that BLV has aÂ considerable prevalence inÂ buffalo inÂ Punjab, Pakistan and there isÂ aÂ dire need toÂ investigate the disease epidemiology atÂ both national and international levels and strategies should beÂ developed toÂ implement anÂ effective control program.","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135274083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0