Veterinarni Medicina最新文献

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Molecular detection of Enterobacter hormaechei in bovine respiratory disease. 牛呼吸道疾病中贺氏肠杆菌的分子检测。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-12-27 eCollection Date: 2024-12-01 DOI: 10.17221/54/2024-VETMED
Hasanain A J Gharban
{"title":"Molecular detection of <i>Enterobacter hormaechei</i> in bovine respiratory disease.","authors":"Hasanain A J Gharban","doi":"10.17221/54/2024-VETMED","DOIUrl":"10.17221/54/2024-VETMED","url":null,"abstract":"<p><p>Bovine respiratory disease (BRD) develops from complex interactions among environmental, host and pathogenic factors. This study aimed to phenotypically identify <i>Enterobacter hormaechei</i> isolated from cattle with BRD and assess antimicrobial susceptibility and determining the molecular phylogeny of local <i>E. hormaechei</i> strains. Between November 2023 and March 2024, nasal swabs were collected from 93 cattle with BRD, before culturing for phenotypic analysis, and performing the polymerase chain reaction (PCR) for molecular characterisation. Of the 93 samples evaluated, 15.79% and 24.56% tested positive for <i>E. hormaechei</i> isolates on culture and PCR, respectively. The local isolates exhibited high resistance to amoxicillin, ampicillin, amikacin, nalidixic acid and ceftazidime; high susceptibility to azithromycin, levofloxacin, gentamicin, ofloxacin, cefepime, ceftriaxone, cefotaxime, nitrofurantoin, ceftazidime and ciprofloxacin; and moderate susceptibility to ciprofloxacin, colistin, imipenem and meropenem. Multiple sequence alignment, phylogenetic tree analysis and homology sequence identification, showed that the five positive isolates were similar to the reference isolate. To the best of our knowledge, this is the first time that <i>E. hormaechei</i> has been isolated in cattle with BRD in Iraq. Because phenotype-based assays show limited accuracy to identify species, we recommend molecular and phylogenetic analysis be included in all similar studies in the future.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 12","pages":"403-412"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy and reliability of tibial torsion measurement using radiography and ultrasound in dogs. 利用x线摄影和超声测量犬胫骨扭转的准确性和可靠性。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-12-27 eCollection Date: 2024-12-01 DOI: 10.17221/50/2024-VETMED
Minseung Jeong, Kyuman Kwack, Jongyeol Kim, Yong Yu, Suyoung Heo
{"title":"Accuracy and reliability of tibial torsion measurement using radiography and ultrasound in dogs.","authors":"Minseung Jeong, Kyuman Kwack, Jongyeol Kim, Yong Yu, Suyoung Heo","doi":"10.17221/50/2024-VETMED","DOIUrl":"10.17221/50/2024-VETMED","url":null,"abstract":"<p><p>Tibial torsion assessment is crucial for understanding deformities and malalignments that can lead to joint pathologies in dogs. Different methods such as radiography, computed tomography (CT), and three-dimensional (3D) volume-rendering techniques have been employed to measure tibial torsion. This study compared the accuracy and reliability of tibial torsion angle (TTa) measurements obtained using radiography and ultrasound tilting techniques against those obtained using the 3D volume-rendering method in small-to-medium-sized non-chondrodystrophic dogs. Seven dogs with 11 hind limbs were included in this study. Descriptive statistics revealed mean TTa values for radiography (1.6° ± 5.14°), ultrasound (2.92° ± 3.98°), CT (4.57° ± 3.44°), and 3D volume-rendering method (5.29° ± 3.30°). Intraclass correlation coefficient (ICC) analysis indicated excellent intra- and interobserver agreement between the radiography and ultrasound methods. Correlation analysis showed positive correlations between all the methods. These findings demonstrate that radiography and the ultrasound tilting technique are reliable alternatives for measuring TTa. Although slightly lower ICC values were observed than those of the 3D volume-rendering technique, the radiography and ultrasound methods still exhibited good to excellent reliability, suggesting that these alternative methods could be effective diagnostic tools for assessing TTa in clinical settings with high accuracy and reliability.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 12","pages":"427-436"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A serological survey of wild boar in Serbia for Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae. 塞尔维亚野猪肺炎支原体和胸膜肺炎放线杆菌血清学调查。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-12-27 eCollection Date: 2024-12-01 DOI: 10.17221/64/2024-VETMED
Milan Ninkovic, Jelena Maksimovic Zoric, Dragica Vojinovic, Ljubisa Veljovic, Nemanja Jezdimirovic, Jasna Kureljusic, Jadranka Zutic
{"title":"A serological survey of wild boar in Serbia for <i>Mycoplasma hyopneumoniae</i> and <i>Actinobacillus pleuropneumoniae</i>.","authors":"Milan Ninkovic, Jelena Maksimovic Zoric, Dragica Vojinovic, Ljubisa Veljovic, Nemanja Jezdimirovic, Jasna Kureljusic, Jadranka Zutic","doi":"10.17221/64/2024-VETMED","DOIUrl":"10.17221/64/2024-VETMED","url":null,"abstract":"<p><p><i>Mycoplasma hyopneumoniae</i> and <i>Actinobacillus pleuropneumoniae</i> are causative agents of the porcine respiratory disease complex. However, information on the prevalence of these pathogens in wild boars is scarce. This study aimed to investigate the presence of antibodies to <i>Mycoplasma hyopneumoniae</i> and <i>Actinobacillus pleuropneumoniae</i> in wild boars in Serbia. In this study 253 serum samples from wild boars were tested for antibodies to <i>Mycoplasma hyopneumoniae</i> and <i>Actinobacillus pleuropneumonia</i> using the ELISA assay. The overall seroprevalence rates of <i>Mycoplasma hyopneumoniae</i> and <i>Actinobacillus pleuropneumoniae</i> were 4.2% and 56.9%, respectively. Antibodies to both pathogens were detected in 20 sera samples (7.9%). The prevalence of wild boars that were seropositive for <i>Mycoplasma hyopneumoniae</i> differed with age and ranged from 10.7% to 33.3%, and for <i>Actinobacillus pleuropneumoniae,</i> it ranged from 51.8% to 83.3%. Wild boars are hard to control and are considered a high-risk infection source for outdoor and backyard pigs and eventually for commercial indoor farms as well. Thus, the result of this first serosurvey in Serbia should raise awareness of the importance of wild boars as potential reservoirs of bacterial pathogens such as <i>Mycoplasma hyopneumoniae</i> and <i>Actinobacillus pleuropneumoniae</i>. Our data revealed the circulation of both pathogens in wild boars in Serbia, drawing attention to the potential health risk they present for domestic swine health.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 12","pages":"413-419"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of urine protein to creatinine ratio in sighthound breeds. 犬种尿蛋白/肌酐比值的评价。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-12-27 eCollection Date: 2024-12-01 DOI: 10.17221/74/2024-VETMED
Simona Kovarikova, Denisa Jurujova, Kristyna Panykova, Jana Blahova
{"title":"Evaluation of urine protein to creatinine ratio in sighthound breeds.","authors":"Simona Kovarikova, Denisa Jurujova, Kristyna Panykova, Jana Blahova","doi":"10.17221/74/2024-VETMED","DOIUrl":"10.17221/74/2024-VETMED","url":null,"abstract":"<p><p>The breed can influence the results of haematological and biochemical blood tests, with sighthounds traditionally mentioned. It may also affect certain urinary parameters. This study aimed to compare urinary protein and creatinine concentrations and their ratio (UPC, urine protein to creatinine ratio) between sighthounds and non-sighthounds and to evaluate these parameters in various sighthound breeds. Urine samples from clinically healthy dogs were collected via normal voiding, representing both sighthound and non-sighthound breeds. The protein and creatinine concentrations in the urine samples were determined, and their ratio was subsequently calculated. A total of 191 urine samples from sighthounds and 90 urine samples from non-sighthound breeds used as a control group were evaluated in the study. In sighthounds, significantly lower urinary protein concentration (248.8 mg/l and 299.8 mg/l, respectively; <i>P</i> = 0.045) and significantly higher urinary creatinine concentration (23.0 mmol/l and 17.5 mmol/l, respectively; <i>P</i> = 0.000) and lower UPC values (0.13 and 0.18, respectively; <i>P</i> = 0.000) were observed in comparison to the entire control group. The UPC values were found to be significantly lower in Greyhounds and Spanish Greyhounds compared with non-sighthounds. Although statistically significant changes were identified, they are unlikely to be of great clinical importance.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 12","pages":"420-426"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum. 勘误。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-11-29 eCollection Date: 2024-11-01 DOI: 10.17221/97/2024-VETMED
S W Pak, S J Lee, W I Kim, Y G Yang, Y K Cho, J S Kim, T W Kim, J W Ko, J C Kim, S H Kim, I S Shin
{"title":"Erratum.","authors":"S W Pak, S J Lee, W I Kim, Y G Yang, Y K Cho, J S Kim, T W Kim, J W Ko, J C Kim, S H Kim, I S Shin","doi":"10.17221/97/2024-VETMED","DOIUrl":"https://doi.org/10.17221/97/2024-VETMED","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.17221/77/2023-VETMED.].</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 11","pages":"401"},"PeriodicalIF":0.6,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel pigeon paramyxovirus type 1 isolated from a sick racing pigeon in the Qinghai-Tibet Plateau of China shows high virulence in chickens. 从中国青藏高原病赛鸽中分离出一种新型1型鸽副粘病毒,在鸡中表现出高毒力。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-11-28 eCollection Date: 2024-11-01 DOI: 10.17221/15/2024-VETMED
Lina Tong, Xiaolong Gao, Ling Feng, Dongliang Yao, Xueqi Zhang, Yinggui Du, Yiyi Zhou, Fuhui Chen
{"title":"A novel pigeon paramyxovirus type 1 isolated from a sick racing pigeon in the Qinghai-Tibet Plateau of China shows high virulence in chickens.","authors":"Lina Tong, Xiaolong Gao, Ling Feng, Dongliang Yao, Xueqi Zhang, Yinggui Du, Yiyi Zhou, Fuhui Chen","doi":"10.17221/15/2024-VETMED","DOIUrl":"10.17221/15/2024-VETMED","url":null,"abstract":"<p><p>Pigeon paramyxovirus type-1 (PPMV-1) is the causative agent of pigeon Newcastle disease (ND), which has caused huge losses to the pigeon industry. In this study, a PPMV-1 strain, PPMV-1/QH-01/CH/23, was isolated from a sick racing pigeon in the Qinghai-Tibet Plateau, China in 2023. The mean death time of chicken embryos and the intracerebral pathogenicity index (ICPI) were 76.8 h and 1.25, indicating a mesogenic strain. Pigeon morbidity and mortality were 100% and 80%, respectively, and both were 80% in chickens; therefore, this isolate was velogenic for both pigeons and chickens. The fusion gene was amplified and sequenced for phylogenetic analysis, and the results indicated that the isolated strain possessed a virulent fusion protein cleavage site motif, <sup>112</sup>R-R-Q-K-R-F<sup>117</sup>, and belonged to genotype XX (former sub-genotype VIc) of class II; this was different from the predominant sub-genotype, VI.2.1.1.2.2, which is prevalent in pigeons. To the best of our knowledge, this is the first report of a novel genotype XX isolate possessing high virulence for both chickens and pigeons in the Qinghai-Tibet Plateau, China.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 11","pages":"389-394"},"PeriodicalIF":0.6,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The beauty of the beast: Suggestions to curb the excesses of dog breeding and restore animal welfare - Invited review. 野兽之美:遏制过度养狗和恢复动物福利的建议 - 特邀评论。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-11-28 eCollection Date: 2024-11-01 DOI: 10.17221/62/2024-VETMED
Claire Diederich
{"title":"The beauty of the beast: Suggestions to curb the excesses of dog breeding and restore animal welfare - Invited review.","authors":"Claire Diederich","doi":"10.17221/62/2024-VETMED","DOIUrl":"10.17221/62/2024-VETMED","url":null,"abstract":"<p><p><i>Dog. Specifically created to save its master's life. - (The dog is the ideal) Friend of man, (because it is his devoted slave)</i> (source: Gustave Flaubert, Dictionnaire des Idées Reçues). But is man the best friend of the dog? This question is legitimate when we consider living situations to which modern domestic dogs are exposed. They often do not satisfy basic animal needs. In this narrative review, the author revisits the history of the dog's presence alongside humans, in the light of current knowledge. The modern dog (breed standards and their interests in canine research) and its breeding strategy, including extreme breeding, will then be given particular attention. Dysfunctional human psychological processes will be explored to make it possible to grasp why the breeding of the modern dog is undergoing such a transformation. Finally, based on these factual and conceptual insights, suggestions to improve canine welfare will be proposed. To be effective, all these must be assessed against real-world conditions.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 11","pages":"369-380"},"PeriodicalIF":0.6,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study on the measurement of the reference range of the whole blood viscosity in Thoroughbred horses. 关于测量纯血马全血粘度参考范围的研究。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-11-22 eCollection Date: 2024-11-01 DOI: 10.17221/24/2024-VETMED
Yongsu Ha, Kangwoo Yi, Chul Park, Gyumin Kim, Daeyoung Choi, Jumjae Lee, Namsoo Kim
{"title":"A study on the measurement of the reference range of the whole blood viscosity in Thoroughbred horses.","authors":"Yongsu Ha, Kangwoo Yi, Chul Park, Gyumin Kim, Daeyoung Choi, Jumjae Lee, Namsoo Kim","doi":"10.17221/24/2024-VETMED","DOIUrl":"10.17221/24/2024-VETMED","url":null,"abstract":"<p><p>This study aimed to measure the whole blood viscosity (WBV) in racehorses using a new viscometer and establish reference values, as well as to investigate the correlation between the WBV and the haematological parameters and serum chemistry. WBV measurements were conducted on 51 Thoroughbred horses using a novel U-shaped scanning capillary-tube viscometer. The reference values for the WBV were determined at various shear rates ranging from 1 s<sup>-1</sup> to 1 000 s<sup>-1</sup>. Correlation analyses were performed to examine the correlation between the WBV and the haematological and serum chemistry parameters. The findings provide valuable reference data for the WBV in Thoroughbred horses and enhance understanding of the relationship between the WBV and routine blood tests in equine health assessment.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 11","pages":"381-388"},"PeriodicalIF":0.6,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robinia pseudoacacia poisoning in two horses: A case report. 两匹马刺槐中毒1例。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-11-21 eCollection Date: 2024-11-01 DOI: 10.17221/55/2024-VETMED
Tereza Novotna, Eva Samonilova, Jaroslav Klan, Lucia Frgelecova, Anna Mala, Zdenka Svobodova, Zuzana Drabkova
{"title":"<i>Robinia pseudoacacia</i> poisoning in two horses: A case report.","authors":"Tereza Novotna, Eva Samonilova, Jaroslav Klan, Lucia Frgelecova, Anna Mala, Zdenka Svobodova, Zuzana Drabkova","doi":"10.17221/55/2024-VETMED","DOIUrl":"10.17221/55/2024-VETMED","url":null,"abstract":"<p><p>This case report describes the poisoning of two mares from the same paddock with <i>Robinia pseudoacacia</i> (Black locust) bark. The poisoning manifested itself by the sudden onset of weakness and fever with transient improvement after the administration of non-steroidal anti-inflammatory drugs and fluids. After the initial stabilisation, the mares were left unattended overnight. One of them was found dead in the morning. The surviving mare developed colic and severe encephalopathy and had to be referred to the clinic. Blood tests revealed severe hyperammonaemia. After four days of symptomatic treatment, she fully recovered. <i>Robinia pseudoacacia</i> with bark freshly bitten off was found in the paddock. The necropsy of the dead mare revealed oedema of the brain and lungs, pleural haemorrhages, and hyperaemia and haemorrhages of the glandular mucosa of the stomach. The intestinal content was watery, without macroscopic findings of the bark. Due to the peracute onset in both mares at the same time, hyperammonaemia and paralytic ileus in the surviving mare, and the presence of <i>Robinia pseudoacacia</i> in the paddock, poisoning with this tree was highly suspected. The diagnosis was confirmed by the microscopic findings of <i>Robinia pseudoacacia</i> bark tissue in the gastric content of the dead mare.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 11","pages":"395-400"},"PeriodicalIF":0.6,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
N-acetyl-β-D-glucosaminidase in clinically healthy German Shepherd dogs and dogs with early stages of chronic kidney disease. 临床健康德国牧羊犬和慢性肾病早期犬体内的 N-乙酰基-β-D-葡萄糖苷酶。
IF 0.6 4区 农林科学
Veterinarni Medicina Pub Date : 2024-10-31 eCollection Date: 2024-10-01 DOI: 10.17221/34/2024-VETMED
Nikola Marecakova, Jana Kacirova, Csilla Tothova, Aladar Madari, Marian Madar, Maria Kuricova, Slavomir Hornak
{"title":"<i>N</i>-acetyl-β-D-glucosaminidase in clinically healthy German Shepherd dogs and dogs with early stages of chronic kidney disease.","authors":"Nikola Marecakova, Jana Kacirova, Csilla Tothova, Aladar Madari, Marian Madar, Maria Kuricova, Slavomir Hornak","doi":"10.17221/34/2024-VETMED","DOIUrl":"10.17221/34/2024-VETMED","url":null,"abstract":"<p><p>Urinary <i>N</i>-acetyl-β-D-glucosaminidase (NAG) activity is associated with kidney disease. In our study, we focused on evaluating the ratio of NAG to the urinary creatinine concentration (NAG/Cr) in the German Shepherd breed. Sixty-two healthy dogs and thirteen dogs with chronic kidney disease (CKD) were examined. The healthy dogs were divided into groups based on their sex and age (puppies and adolescent dogs under 2 years, adult dogs from 2 to 6 years and seniors over 6 years), while the dogs with CKD were divided based on the disease stage (CKD stage 1 and 2). No significant difference was detected between the males and females. Regarding the age dependence, significantly higher values were found in dogs older than 6 years (<i>P</i> = 0.020 3) compared to dogs aged 2-6 years. When comparing the healthy dogs to the dogs with CKD, the lowest NAG/Cr ratio was observed in the dogs with CKD stage 2. The reference interval for NAG/Cr in the German Shepherd was established in the range of 0.78-7.86 U/gCr. We observed no correlations with the commonly used markers of kidney disease such as creatinine, urea, or symmetrical dimethylarginine. Nevertheless, we encourage the further investigation of NAG in relation to CKD, taking the breed, sex and age of the patients into account.</p>","PeriodicalId":23532,"journal":{"name":"Veterinarni Medicina","volume":"69 10","pages":"337-344"},"PeriodicalIF":0.6,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11581467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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