Vasa-european Journal of Vascular Medicine最新文献

{"title":"Curbing diagnostic delay in peripheral arterial disease - Time to shift from late recognition to early diagnosis.","authors":"Mette Søgaard, Christos Rammos","doi":"10.1024/0301-1526/a001255","DOIUrl":"https://doi.org/10.1024/0301-1526/a001255","url":null,"abstract":"","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":"55 3","pages":"165-166"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Because we're worth it!","authors":"Katja S Mühlberg","doi":"10.1024/0301-1526/a001265","DOIUrl":"https://doi.org/10.1024/0301-1526/a001265","url":null,"abstract":"","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":"55 3","pages":"239-240"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is altered hemodynamics the main culprit for failure of covered stents?","authors":"Aleš Blinc, Vinko Boc","doi":"10.1024/0301-1526/a001233","DOIUrl":"https://doi.org/10.1024/0301-1526/a001233","url":null,"abstract":"","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":"55 3","pages":"167-168"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Mansoor's self-report tool for cardiovascular risk assessment predicts major adverse cardiovascular and cerebrovascular events and amputations in peripheral artery disease.","authors":"Markus Vosseler, Lukas Hobohm, Volker H Schmitt, Omar Hahad, Thomas Münzel, Philipp Lurz, Christine Espinola-Klein, Karsten Keller","doi":"10.1024/0301-1526/a001281","DOIUrl":"https://doi.org/10.1024/0301-1526/a001281","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Peripheral artery disease (PAD) constitutes a major global burden of disease. Regarding patient-cases of patients with PAD, it is of outstanding interest to identify patients with a high risk for adverse in-hospital events. Thus, risk stratification tools including scores are of key interest for prognosis prediction. <i>Materials and methods:</i> The German nationwide inpatient statistics 2005-2018 was used for this analysis. Patient-cases of PAD patients were stratified according to a modified Mansoor's Self-Report Tool for Cardiovascular Risk Assessment class and compared. The predictive performance of this score was evaluated to predict adverse in-hospital events with the help of unadjusted and adjusted logistic regressions. <i>Results:</i> Overall, 2,462,085 patient-cases (36.8% females; 57.4% ≥ 70 years) of patients hospitalised due PAD were included in Germany 2005-2018. According to the Mansoor's self-report tool for cardiovascular risk assessment, 1,101,123 (44.7%) of the PAD patient-cases were classified as low-risk and 1,360,962 (55.3%) as high-risk. High-risk class was predictive for major adverse cardiovascular and cerebrovascular events (MACCE; odds ratio [OR] 1.09 [95% confidence interval [CI] 1.07-1.10], p < .001), acute kidney injury (OR 1.33 [95% CI 1.30-1.36], p < .001) and amputations (OR 1.46 [95% CI 1.44-1.47], p < .001). In contrast, high risk class was not associated with increased rate of arterial and venous embolism/thrombosis and in-hospital death (OR 0.97 [95% CI 0.96-0.99], p < .001). High risk class was associated with coronary revascularization treatments. <i>Conclusions:</i> The modified Mansoor's Self-Report Tool for Cardiovascular Risk Assessment score is a new and effective risk stratification tool to predict individual risk regarding MACCE, acute kidney injury and amputations in PAD patients during their hospitalisation, but the score failed to predict for in-hospital mortality.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health and quality of life in patients with leg lymphedema during maintenance phase.","authors":"Thomas Benz, Stephan Wagner, Susanne Lehmann, Peter S Sándor, Felix Angst","doi":"10.1024/0301-1526/a001290","DOIUrl":"https://doi.org/10.1024/0301-1526/a001290","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Complex decongestive therapy (CDT) is the standard conservative treatment for lymphedema. This study aims to provide insights into the maintenance phase of CDT, its impact on health and quality of life over six months, and identify factors influencing these outcomes in individuals with leg lymphedema. <i>Patients and methods:</i> This prospective cohort study assessed health and quality of life by Short-Form-36, Freiburg Quality of Life Assessment for lymphatic disorders (FLQA-lk), Knee Outcome Survey Activities of Daily Living Scale, Symptom Checklist-90 Revised, and Coping Strategies Questionnaire. Health status was expressed by means (±<i>SD</i>) and standardised response means (SRMs). Multivariate linear regression explored the score change of FLQA-lk. <i>Results:</i> Participants were on average aged 53.9 years, female (75.9%), and had two comorbidities (n = 87). On 22/26 dimensions, average improvements ranged from 8.7 to 0.7 (scores) respectively from -0.05 to 0.51 (SRMs). Most participants (89.7%) continued with manual lymphatic drainage and wore stockings regularly (95%) at baseline. Formal education, exercise and compression showed the highest, in trend statistically significant partial correlations. <i>Conclusions:</i> Health and quality of life in individuals with leg lymphedema can be stabilised and slightly improved during the maintenance phase of the CDT with regular use of compression stockings and manual lymphatic drainage.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and patient-reported outcomes after drug-coated balloon angioplasty for femoropopliteal peripheral artery disease.","authors":"Benedetta Madaro, Camilla Cippa, Noel Chan, Naomi Elbaranes, John W Eikelboom, Maya Abrishami Kashani, Leonie Rimann, Tim Sebastian, Alessandro Squizzato, Nils Kucher, Stefano Barco","doi":"10.1024/0301-1526/a001283","DOIUrl":"https://doi.org/10.1024/0301-1526/a001283","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Drug-coated balloons (DCB) reduce restenosis and reintervention in femoropopliteal peripheral artery disease (PAD), but uncertainty remains regarding benefit in terms of clinical outcomes and long-term safety. This systematic review and meta-analysis compared clinical and functional outcomes of patients receiving DCB versus plain old balloon (POBA) angioplasty. <i>Materials and methods:</i> Randomised trials comparing DCB versus POBA for symptomatic femoropopliteal PAD were searched in MEDLINE, Embase, and CENTRAL (inception to 14 October 2025). Studies including below-the-knee disease were excluded. Groups were compared for the incidence of major amputation, clinically driven target lesion revascularization (CD-TLR), as defined by individual trials, major adverse limb events (MALE), and all-cause death, as well as improvement in Rutherford classification, EuroQol-5, Walking-Impairment-Questionnaire, and six-minute-walking-test. Pooled risk ratios and mean differences were calculated using random-effects models. <i>Results:</i> We included 27 trials (4,248 patients: DCB = 2,507 of whom 2,506 treated with paclitaxel-coated balloons; POBA = 1,741). DCB significantly reduced CD-TLR (relative risk (RR) 0.53; 95% confidence interval (CI):0.44-0.64, p < .01). The proportion of patients with improvement of at least one Rutherford category was greater after DCB at 6-12 months (6 months: RR 1.11 [95% CI: 1.03-1.20], p = .005, 12 months: RR 1.06 [95% CI: 1.01-1.12], p = .03), but not at 24 months. We found no evidence of differences between groups for any of the other outcomes with results consistent across subgroups (DCB type, native vs. in-stent, low-risk-of-bias trials). <i>Conclusions:</i> Among patients with femoropopliteal PAD, paclitaxel-coated balloon angioplasty reduced CD-TLR, and improved Rutherford category compared with POBA. We did not find evidence to support the use of paclitaxel-coated balloons to reduce the risk of major amputation or MALE, whereas it did not appear to influence the risk of death at long-term follow-up.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiosarcoma masquerading as popliteal artery aneurysm.","authors":"Ursula Elisabeth Maria Werra, Eva Wardelmann, Marco Aleksic, Michael Brockmann, Frauke Verrel, Bernhard Dorweiler, Alexander Kania","doi":"10.1024/0301-1526/a001289","DOIUrl":"https://doi.org/10.1024/0301-1526/a001289","url":null,"abstract":"<p><p><b></b> <i>Background:</i> This research was carried out to identify relevant steps to diagnosis and possible treatment regimens regarding angiosarcomas of the popliteal artery associated with true popliteal aneurysms, as they are very rare. <i>Materials and methods:</i> A systematic literature search was conducted in accordance with the Prisma Guidelines. Only publications regarding true popliteal aneurysms in association with true angiosarcomas were taken into account. Furthermore, three well-documented not yet published cases are depicted. <i>Results:</i> 13 case reports could be identified. Besides two initially diagnosed cases (ID), all other cases were diagnosed secondary (<i>SD</i>) and underwent surgery due to ipsilateral aneurysms in the past. For the reported cases, pain was the most frequent symptom (61%), followed by oedema (46%) and localised swelling in the popliteal fossa. 38% of patients showed central metastasis at the time of diagnosis. Both ID patients underwent primary resection of the tumour - in one case followed by arterial reconstruction, local radiotherapy and regional hyperthermal perfusion. 45% of <i>SD</i> patients underwent sole major amputation, the others received varying treatment regimens (chemotherapy, radiotherapy (or combination)) or sole palliative care. The short available follow-up of the two ID cases was uneventful. The median survival time for <i>SD</i> patients treated by major amputation was 8 months (average 19.2 months) and for the others in median 4.5 months (average 11 months). <i>Conclusions:</i> Non-ischaemic pain, swelling and/or sudden regrowth years after treatment of a popliteal aneurysm are highly suspect of malignancy and should be further evaluated (e.g. biopsy/positron emission tomography computed tomography).</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating native arteries, bypasses and in-stent-restenosis with rotational athero-thrombectomy - two-year results from the Rotarex-PMCF trial.","authors":"Michael Lichtenberg, Nasser Malyar, Torsten Fuss, Dierk Scheinert, Lars Maiwald, Jörg Tessarek, Romaric Loffroy, Mattia Mirandola, Rick de Graaf, Florian Wolf, Beatriz Monsalve-Roquero, Thomas Zeller","doi":"10.1024/0301-1526/a001282","DOIUrl":"https://doi.org/10.1024/0301-1526/a001282","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Atherectomy devices have become a widely used tool to treat peripheral vessels in a variety of clinical situations. This trial assesses the efficacy, safety and clinical success of the Rotarex Catheter, a rotational athero-thrombectomy system, for the treatment of acute, subacute and chronic occlusions in peripheral arteries including native arteries, bypasses and in-stent restenosis, used alone or as an adjunctive tool. <i>Patients and methods:</i> 220 patients were enrolled in this prospective, multicentre, single-arm study in Europe. Procedural success was measured after the index procedure. Freedom from major adverse events (MAEs), was collected through 30 days. Primary patency was collected at 1, 6, 12, and 24 months. Secondary outcomes included safety events, freedom from target lesion and vessel revascularization (TLR and TVR) and quality of life improvement. <i>Results:</i> Procedural success of Rotarex with an adjunctive treatment was 94.1%. Primary patency was 87.2%, 68.1%, 57.8% and 49.1% at 1, 6, 12 and 24 months, respectively. Freedom from MAEs through 30 days was 96.3%. The MAE rate was 21.0%, 31.0% and 41.1% at 6, 12 and 24 months. Freedom from TLR was 97.7%, 81.0%, 72.0% and 64.3% at 1, 6, 12 and 24 months. Freedom from TVR was 95.8%, 79.0%, 69.9% and 62.3% at 1, 6, 12 and 24 months. Most subjects showed improvement in Rutherford Class and in the quality-of-life measures. <i>Conclusions:</i> These results show that Rotarex performs effectively and safely when it is being used as an adjunctive treatment in acute, subacute and chronic occlusions of native arteries, ISR and bypass.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Objective performance goals after open and endovascular intervention for critical limb ischaemia.","authors":"Eike Sebastian Debus, Jasmin Epple, Carl-Leon Reese, Rejane Golbach, Reinhart T Grundmann","doi":"10.1024/0301-1526/a001285","DOIUrl":"https://doi.org/10.1024/0301-1526/a001285","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Whether current real-world treatment of critical limb ischemia with lower extremity bypass (LEB) or infrainguinal endovascular intervention (IEI) meets the Society for Vascular Surgery objective performance goals (OPG) was investigated. <i>Materials and methods:</i> Literature search in PubMed, studies from 2010 to March 2021. A total of 35,981 endovascular interventions were reported in 82 publications and 26,707 open procedures in 49 publications. <i>Results:</i> Perioperative major adverse limb events was 8% (OPG) versus 9% for IEI and 10% for LEB (no significant differences). Perioperative major adverse cardiovascular events was significantly better with IEI (4%; p < .001) and LEB (6%; p = .018) than the OPG (8%). After 1 year, amputation-free survival (AFS) was 76.5% (OPG), compared to 71% with IEI (p = .932) and 77% with LEB (p = .006) and patient survival was 85.7% (OPG) compared to 84% (LEB; p = .006) and 78% (IEI; p = .102). 5-year survival was 51% with LEB and 45% with IEI (p = .320), and AFS was 44% with LEB and 46% with IEI (p = .802). 5-year OPGs were not reported. <i>Conclusions:</i> In the studies analysed, the results after IEI and LEB largely corresponded to the OPGs. 5-year outcomes after LEB and IEI did not differ significantly.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient participation in supervised exercise therapy and its impact on outcomes and quality of life in peripheral arterial disease.","authors":"Waseem Garabet, Katharina Henrika Beckamp, Polina Shabes, Markus Udo Wagenhäuser, Amir Arnautovic, Artis Knapsis, Philip Dueppers, Nadja Kairies-Schwarz, Hubert Schelzig, Julian-Dario Rembe","doi":"10.1024/0301-1526/a001280","DOIUrl":"https://doi.org/10.1024/0301-1526/a001280","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Supervised Exercise Therapy (SET) improves walking performance in patients with peripheral arterial disease (PAD) and intermittent claudication, yet implementation and adherence remain inconsistent. This study evaluated functional outcomes, ankle-brachial index (ABI), quality of life (QoL), and adherence to SET in a real-world clinical setting. <i>Materials and methods:</i> This monocentric retrospective cohort study included 190 patients with PAD Fontaine stage II treated at a university vascular outpatient clinic between 01.01.2018 and 31.12.2022. Exposure was participation in SET compared with standard care without SET. Claudication onset distance (COD), peak walking distance (PWD), and ABI were assessed at baseline and after 3, 6, 12, and 24 months. Health-related QoL was evaluated using the SF-36 questionnaire. Adherence and reasons for dropout or non-participation were extracted from medical records. <i>Results:</i> Of the 190 patients (mean age 71.4 years; 60.5% male), 32 (16.8%) completed 12 months of SET, while 158 (83.2%) served as the comparison group. SET participants were older and predominantly male. COD and PWD improved significantly after 6 months (p = .0001 and p = .041) and continued to rise through 24 months, whereas ABI showed no significant changes. Adherence to SET was low. Dropout was mainly related to clinical deterioration, comorbidities, or hospitalisation, with additional sociodemographic and motivational barriers contributing to non-participation. SF-36 scores did not differ significantly, although trends toward reduced pain and improved physical functioning were observed. <i>Conclusions:</i> In this single-centre cohort, SET was associated with improved walking performance but low adherence and no significant changes in ABI or overall QoL.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}