Vasa-european Journal of Vascular Medicine最新文献

{"title":"Chronic venous disease - an update on pathophysiology, diagnosis and management.","authors":"Bernhard Zierfuss, Christof Zerweck, Markus Theurl, Marco Fresa, Sabine Steiner, Oliver Schlager","doi":"10.1024/0301-1526/a001291","DOIUrl":"https://doi.org/10.1024/0301-1526/a001291","url":null,"abstract":"<p><p><b></b> Chronic venous disease (CVD) is a common disease, affecting up to 20% of the general population. In later clinical stages of venous refluxive disease dwelling oedema, skin changes and leg ulcers can occur. Therapeutic options comprise compression therapy and several minimal-invasive as well as open surgery treatments. Venous leg ulcers, as well as mixed arterial-venous leg ulcers inflict high socioeconomic and health care system burden. Despite both the high prevalence as well as the high cost, timely and effective treatment are often delayed. Thus, this review summarizes all of these mentioned aspects of CVD.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upper extremity arterial occlusion - A new hallmark of pseudoxanthoma elasticum.","authors":"Max Jonathan Stumpf, Annemarie Lenzen, Marit Siebigteroth, Arthur Hartmann, Leonie Weinhold, Dirk Skowasch, Georg Nickenig, Nadjib Schahab, Christian Alexander Schaefer","doi":"10.1024/0301-1526/a001284","DOIUrl":"https://doi.org/10.1024/0301-1526/a001284","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Pseudoxanthoma elasticum (PXE) is a rare, genetic disorder characterised by progressive vision loss, skin changes, and early-onset arteriosclerosis. The latter makes PXE a risk factor not only for peripheral artery disease (PAD) but may also promote coronary artery disease. In this context, patients with PXE have repeatedly reported problems with the radial access during coronary angiography. Therefore, the aim of this study was to prospectively investigate the prevalence of upper extremity (UE) arterial occlusion in patients with PXE and to identify possible associated risk factors. <i>Patients and methods:</i> Between November 2022 and February 2024, 93 consecutive patients with PXE were examined. 65 eligible patients with PXE were retained for further analysis and compared with 57 in-hospital controls. All patients underwent extensive screening for UE arterial disease using colour-coded duplex sonography (CCDS). <i>Results:</i> UE artery occlusion was significantly more common in patients with PXE than in the control group (58.5% vs. 3.5%; p < .001). The radial arteries were most commonly affected, predominantly bilaterally (50.8% of all PXE patients). Age was significantly associated with the presence of UE artery occlusion with an odds ratio (OR) of 1.06 (confidence interval [CI]: 1.01-1.10; p = .013). <i>Conclusions:</i> Peripheral occlusion of the UE arteries is a common finding in patients with PXE. In clinical practice, these findings suggest that patients with PXE may require a screening for PAD and occlusion of the arteries of the UE using CCDS after the age of 40 years. This is particularly recommended prior to coronary angiography or percutaneous coronary intervention.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rapid review of pathways to diagnosis for people living with peripheral artery disease.","authors":"Zoe Clothier, Jo Armes, Christian Heiss, Jenny Harris","doi":"10.1024/0301-1526/a001241","DOIUrl":"10.1024/0301-1526/a001241","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Peripheral artery disease (PAD) remains under-recognised. Low awareness among the public, patients and healthcare professionals (HCPs) contributes to delayed diagnosis and poorer outcomes. This rapid review applied the Model of Pathways to Treatment (MPT) to synthesise behavioural and system-level factors shaping the diagnostic pathway and identifies evidence gaps to inform intervention and service redesign. <i>Patients and methods:</i> Databases (CINAHL, PubMed, PsycINFO) were searched (January 2001-July 2024) for qualitative, quantitative or mixed-methods studies exploring PAD diagnosis from the perspective of patients, at-risk public or HCPs. Eligible studies examined events, behaviours or timings linked to PAD diagnosis. Quality was assessed using the Mixed Methods Appraisal Tool and findings synthesised using the MPT. <i>Results:</i> Twenty-one studies (13 quantitative, 7 qualitative, 1 mixed method) were included. Mapping to the MPT revealed modifiable, multifactorial barriers across the diagnostic pathway from symptom appraisal to pre-treatment. At the patient level, symptom misattribution, normalisation, competing priorities, fear and financial concerns delayed help-seeking. At the provider level, HCPs often lacked training, confidence or incentives to assess PAD, with underuse of tools including the ankle-brachial index. At the system level, referral delays were linked to unclear pathways and limited feedback from vascular services. Only one study explored variations in diagnosis timeline by population or setting. <i>Conclusions:</i> Although PAD is under diagnosed and associated with poor outcomes, few studies have examined the behavioural and structural factors delaying diagnosis. This review identifies missed opportunities along the diagnostic pathway and highlights targets for future research and intervention across patient, HCP and system levels.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"169-178"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145252982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Off-the-shelf Percutaneous Deep Vein Arterialization (pDVA).","authors":"Ahmad Naga, Noor Hamo, Chloe Lakin, Narayanan Thulasidasan, Hany Zayed","doi":"10.1024/0301-1526/a001229","DOIUrl":"10.1024/0301-1526/a001229","url":null,"abstract":"<p><p><b></b> Peripheral artery disease (PAD) affects up to 10% of people older than 50 years in Western Europe and North America, of which the worst clinical spectrum being chronic limb-threatening ischemia (CLTI). It is estimated that up to 20% of patients with CLTI are deemed un-reconstructable cases due to the absence of a suitable distal target vessel or conduit. Recently, percutaneous deep vein arterialization (pDVA) of the foot has been described to treat these patients. Technically arterialization of the deep foot veins is achieved by creating a communication between one of the tibial arteries with the deep veins in the foot. The Limflow system (Inari Medical TM) is the only CE-approved device for this technique. The PROMISE I, II, and UK provided the evidence to back the use of the Limflow system. Because of the limited availability and high cost of the LimFlow System, several studies have reported various off-the-shelf techniques described by authors attempting to achieve pDVA using alternative devices. In this review, we looked at some technical aspects of off-the-shelf pDVA and examine the outcomes in terms of technical success rates, wound healing rates, amputation free survival rates and re-interventions in comparison to those reported after the use of the Limflow system.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"190-195"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Future of Vascular Medicine in Europe - Insights from the ESVM Survey on Training Experiences and Career Perspectives.","authors":"Giacomo Buso, Jeanne Hersant, Sanjiv Keller, Igli Kalaja, Paola Bigolin, Andrej Džupina, Thomas Gary, Vinko Boc, Marianne Brodmann, Christian Heiss, Juraj Madaric, Adriana Visonà, Lucia Mazzolai","doi":"10.1024/0301-1526/a001221","DOIUrl":"10.1024/0301-1526/a001221","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Vascular medicine/angiology plays a crucial role in managing vascular diseases, yet its recognition, training, and practice vary across Europe. To understand these disparities, the European Society for Vascular Medicine (ESVM) conducted a survey among young trainees to assess their attitudes and perception towards vascular medicine training. <i>Methods:</i> A cross-sectional survey was distributed among trainees and young specialists from European countries, including nations with and without vascular medicine as a recognized specialty. The survey was published on the ESVM website and shared through national vascular medicine societies. Participants provided insights into their training experiences, opinions of the specialty, and priorities for improvement. Statistical analysis compared responses based on specialty recognition. <i>Findings:</i> Among 210 respondents, 36.2% (n=76) were from countries without formal specialty recognition. Training was more structured in countries with a recognized specialty (p<.001). Multidisciplinary team meetings were deemed critical by 98.1% but were more common in countries with a recognized specialty (p=.003). Overall, 80.5% (n=169) expressed interest in training abroad. Core vascular domains were well-covered, while areas like lymphatic and microvascular diseases lacked sufficient training both in countries where the specialty was recognized and where it was not. Respondents from countries with a recognized specialty rated their training significantly higher (p=.001). Despite challenges, 85.2% (n=179) would choose the specialty again, and 90.4% (n=190) supported a unified European certification. <i>Interpretation:</i> These findings highlight the need for a harmonized training framework in Europe ensuring a shared foundational curriculum in vascular medicine while enhancing professional mobility and improving patient care across the whole spectrum of vascular diseases.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"220-228"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of dual antiplatelet therapy following covered femoropopliteal stenting - Why size matters.","authors":"Maria Elisabeth Leinweber, Suzanne Holewijn, Maxime Sibe, Tanja Böhme, Laurens van Walraven, Thomas Zeller, Michel M P J Reijnen, Amun Georg Hofmann","doi":"10.1024/0301-1526/a001227","DOIUrl":"10.1024/0301-1526/a001227","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Endovascular therapy has emerged as an effective minimally invasive approach for treating peripheral artery disease (PAD). Postprocedural dual antiplatelet therapy (DAPT) is commonly used to prevent adverse events, but optimal management remains uncertain. <i>Patients and methods:</i> This international, multicentre retrospective study synthesized data from three studies on covered stents (VIABAHN^® Endoprosthesis) in 437 PAD patients (2001-2015). A dimension index (total stent length/smallest diameter) was developed and externally validated in a second cohort (n=148). <i>Results:</i> Among 321 patients with DAPT, univariate analysis showed no association between the initiation of DAPT and reduced major adverse limb events (MALE). Longer total covered length (aHR: 1.02) and smoking (aHR: 1.43) were associated with increased MALE, while stent diameters of 7-8mm showed a protective effect (aHR: 0.30). Cox proportional hazards models repeatedly showed that both the duration of DAPT and the dimension index (total covered length/smallest stent-graft diameter) were significantly associated with MALE after adjusting for other confounders. However, in a sensitivity analyses, no significant impact of DAPT on MALE was observed in patients with a high dimension index. <i>Conclusions:</i> These findings suggest while longer DAPT strategies might be protective towards MALE, stent-graft properties might be at least as relevant if not more determining regarding impaired outcomes after femoropopliteal interventions. Individualizing DAPT duration based on stent proportions might offer further opportunities for optimized protocols by personalized pharmacological therapies.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"229-238"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical benefits of paclitaxel-coated balloons in the treatment of infrapopliteal limb-threatening peripheral artery disease.","authors":"Charlott Fuß, Hans Krankenberg, Pawel Aftanski, P Christian Schulze, Marcus Thieme","doi":"10.1024/0301-1526/a001217","DOIUrl":"10.1024/0301-1526/a001217","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Infrapopliteal lesions account for one-third of peripheral artery disease (PAD) cases; however, its endovascular treatment data are insufficient. Although paclitaxel-coated drug-coated-balloons (DCBs) reduce restenosis and the need for re-interventions in femoropopliteal arteries, their effectiveness in below-the-knee (BTK) vessels is uncertain. This study evaluated the real-world effectiveness and safety of paclitaxel-coated DCBs in BTK vessels. <i>Patients and methods:</i> This retrospective single-centre study included consecutive patients treated with paclitaxel-coated Luminor™ DCB in BTK arteries between August 2017 and March 2022. The follow-up extended to 60 months. Data were retrieved from archives, phone interviews and physician inquiries. <i>Results:</i> Seventy-nine patients (65.5% male; mean age 74.9±9.2 years) underwent 84 interventions with 114 DCBs. The overall and treated lesion lengths averaged 102.1±80.3 and 117.2±75.5 mm, respectively. The median preoperative Rutherford score was 5 [interquartile range (IQR), 5-5; n=80]. The ankle-brachial index (ABI, 0.8±0.4-1.0±0.2, P=.002) and toe-brachial index (TBI, 0.3±0.3-0.6±0.2, P=.039) significantly improved post-intervention. The wound, ischaemia and foot infection score components showed median value reductions from the pre- to the postinterventional assessment: wound, from 1 (IQR, 1-2) to 1 (0-1); ischaemia, from 1 (IQR, 0-2) to 0 (0-1); and foot infection, from 1 (IQR, 0-2) to 0 (0-1). Kaplan-Meier analysis revealed 25 major adverse limb events, 17 re-interventions, 15 major adverse cardiac events, and 8 major amputation events over 5 years. Re-intervention-free survival was lower in men than in women (P=.036). Diabetic status or renal function was not significantly different. The 3-year mortality was 46.4%. <i>Conclusions:</i> This study highlights the clinical benefit of infrapopliteal paclitaxel-coated DCBs in real-world patients. ABI and TBI improvements reflect ischaemia relief. Wound-healing trends suggest reduced ischaemia and infection within 3 days, but requires longer follow-up. High mortality rates emphasise the effect of comorbidities and multidisciplinary care requirements.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"203-212"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antiplatelets and native arteriovenous fistula dysfunction.","authors":"Ioanna Pouliopoulou, Stefanos Roumeliotis, Konstantinos Leivaditis, Vangelis Bontinis, Alkis Bontinis, Theodora Chatzimpalasi, Vassilios Liakopoulos","doi":"10.1024/0301-1526/a001225","DOIUrl":"10.1024/0301-1526/a001225","url":null,"abstract":"<p><p><b></b> <i>Background:</i> We investigated the safety and efficacy of antiplatelet therapy in preventing native arteriovenous fistula (AVF) dysfunction. <i>Patients and methods:</i> A systematic review was conducted in accordance with the PRISMA 2020 guidelines. Randomized controlled trials (RCTs) evaluating the effects of antiplatelet therapy following native AVF creation were eligible for inclusion. The primary endpoint was AVF primary patency. Secondary endpoints included AVF maturation, abandonment, and overall bleeding. <i>Results:</i> Twelve RCTs, comprising 2,491 patients, were incorporated in the analysis. The included studies assessed aspirin, clopidogrel, ticlopidine, and dypiridamole across various dosing regimens. The postoperative administration of antiplatelets, regardless of the specific drug or dose, was associated with improved AVF primary patency compared to controls or placebo, odds ratio (OR) 2.28 (95% CI: 1.42-3.65). Subgroup analysis showed no significant differences for aspirin 100mg daily or clopidogrel 75mg daily compared to controls/placebo, with ORs of 1.08 (95% CI: 0.76-1.54) and 2.16 (95% CI: 0.95-4.91), respectively. In contrast, ticlopidine 250mg twice daily significantly improved patency, OR 3.48 (95% CI: 1.46-8.26). Additionally non-statistically significant differences were identified between the antiplatelet and control/placebo groups in terms of maturation, OR 1.58 (95% CI: 0.81-3.09), AVF abandonment, risk ratio (RR) 0.93 (95% CI: 0.58-1.50), or overall bleeding RR 1.18 (95% CI: 0.77-1.81). Finally, meta-regression analysis of the antiplatelet groups pooled estimates revealed a negative association between maturation and follow-up duration (β =-0.1235, p<.01), and treatment duration and abandonment outcomes (β =-0.065, p<.01). <i>Conclusions:</i> This review demonstrated the safety and efficacy of antiplatelet therapy in preserving AVF patency, with ticlopidine and clopidogrel emerging as the primary contributors to this outcome. These findings suggest the potentially beneficial role of adenosine diphosphate (ADP) receptor antagonists in maintaining AVF patency.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"179-189"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144970905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systolic acceleration time as an indicator of hemodynamic severity in peripheral artery disease with medial artery calcification.","authors":"Anne-Kathrin Tolke, Bettina-Maria Taute","doi":"10.1024/0301-1526/a001226","DOIUrl":"10.1024/0301-1526/a001226","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Ankle-brachial-index (ABI) calculation is the recommended method in diagnosing peripheral artery disease (PAD) but its use is limited due to medial artery calcification (MAC) which leads to incompressibility of lower limb arteries and results in false elevated ABI values. Measurement of systolic acceleration time (AT) by duplex ultrasound is being discussed as an alternative, but whether coexisting MAC influences AT values remains unknown. <i>Patients and methods:</i> In a prospective clinical study healthy subjects, patients with MAC and patients with PAD with and without MAC were examined. In all 238 participants ABI calculation for posterior tibial artery (ATP) and anterior tibial artery (ATA) was performed by continuous wave (CW) Doppler ultrasonography, followed by measurement of AT derived from velocity-time spectra of ATP, ATA, and brachial artery (AB) by colour-coded duplex sonography. We introduced an innovative parameter to quantify PAD severity: the absolute difference value of AT (DAT), calculated as the absolute difference between crural AT and brachial AT. This parameter aims to minimize confounding effects of cardiac conditions on AT measurements. <i>Results:</i> It was found that a coexisting MAC does not have a significant impact on AT values (p>.05). According to the findings of this study PAD is present in patients with AT >95ms (sensitivity (Se): 85%, specificity (Sp): 87%) or in patients with DAT >20ms (Se: 82%, Sp: 84%). <i>Conclusions:</i> Both AT and DAT are suitable quantitative parameters for PAD diagnosis and severity assessment in patients with coexisting MAC, providing valuable alternatives when ABI is unreliable.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"213-219"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144970870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of duplex ultrasound surveillance after prosthetic femoropopliteal bypass.","authors":"Michaela Kluckner, Wolfgang Hitzl, David Wippel, Laura Schönherr, Sabine Wipper, Leonhard Gruber, Florian K Enzmann","doi":"10.1024/0301-1526/a001216","DOIUrl":"10.1024/0301-1526/a001216","url":null,"abstract":"<p><p><b></b> <i>Background:</i> Current guidelines on the follow-up after infrainguinal bypass recommend clinical examination with history, pulse palpation and ankle-brachial-index assessment. Depending on the guideline, duplex ultrasound may or may not be recommended due to the lack of evidence. Data on this topic is sparse, especially after prosthetic bypass. <i>Patients and methods:</i> In a retrospective single-centre analysis, ultrasound surveillance examinations of 181 patients after femoropopliteal prosthetic bypass were analysed. Flow-velocities and flow-patterns of the inflow, anastomoses, the bypass as well as the outflow vessels were evaluated. The primary endpoint was primary patency, while primary-assisted and secondary patency as well as amputation-free survival were secondary endpoints. <i>Results:</i> By applying the Fine-Gray Model five ultrasound criteria were identified to increase the risk of loss of primary patency. A monophasic flow-pattern of the bypass as well as the popliteal artery showed a hazard-ratio of 2.0 (95% CI: 1.26-3.1, p=.003) and 1.7 (95% CI: 1.09-2.64, p=.02), respectively. A peak systolic velocity <60cm/sec of the deep femoral artery was significantly associated with loss of primary patency (p=.025). Decrease of inflow velocity as well as the deep femoral artery during follow-up were also significantly connected to loss of primary patency (p<.001). Primary-assisted and secondary patency as well as amputation-free survival were significantly associated with the waveform in the bypass and the popliteal artery (p<.001, p=.011, p=.031, p=.013). <i>Conclusions:</i> Ultrasound surveillance after femoropopliteal prosthetic bypass can identify factors associated with lower patency rates and amputation-free survival. These findings can help detect patients at higher risk of bypass occlusion and may improve their outcome.</p>","PeriodicalId":23528,"journal":{"name":"Vasa-european Journal of Vascular Medicine","volume":" ","pages":"196-202"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}