Veterinary journal最新文献

筛选
英文 中文
Potential role of peste des petits ruminants virus in small ruminant abortions 小反刍兽疫病毒在小反刍兽流产中的潜在作用
IF 2.3 2区 农林科学
Veterinary journal Pub Date : 2024-06-20 DOI: 10.1016/j.tvjl.2024.106185
Ş. Murat
{"title":"Potential role of peste des petits ruminants virus in small ruminant abortions","authors":"Ş. Murat","doi":"10.1016/j.tvjl.2024.106185","DOIUrl":"https://doi.org/10.1016/j.tvjl.2024.106185","url":null,"abstract":"<div><p>The aim of the present study was to investigate the frequency, genetic variability, and phylogeny of the peste des petits ruminants virus (PPRV) in ovine and caprine fetuses. During 2014 and 2017, a total of 1054 embryos/fetuses were collected in Turkey. A real-time RT-PCR assay was used for the detection of the PPRV RNA. Genetic characterization and phylogenetic analysis of the PPRV field isolates were conducted by sequencing fusion (F) protein and nucleoprotein (N) gene segments. Samples were also collected from ewes (n = 83) and nanny goats (n = 3) that had aborted and whose embryos/fetuses were found to be PPRV positive. PPRV positive embryos/fetuses were also tested for the presence of <em>Listeria monocytogenes</em>, <em>Campylobacter</em> spp., <em>Coxiella burnetii</em>, <em>Chlamydophila abortus</em>, <em>Brucella</em> spp., akabane virus, aino virus, bluetongue virus, border disease virus, bovine viral diarrhea virus, Cache Valley virus, and Schmallenberg virus. PPRV RNA was detected in 123 (11.7 %) of the 1054 embryos/fetuses, 78 of the 83 (94 %) ewes and 3 (100 %) nanny goats. Border disease virus RNA and <em>Chlamydophila abortus</em> DNA were detected in 7 and 12 PPRV positive sheep fetuses, respectively, while other bacterial and viral agents were not detected. Phylogenetically, the field isolates in this study belong to lineage IV, and compared to other strains of lineage IV considered in this study, they showed 1 and 5 new amino acid substitutions in the F and N gene sequences, respectively. The results of the study suggest that PPRV plays an important role in abortion. Therefore, PPRV needs to be taken into consideration in sheep and goats abortions.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106185"},"PeriodicalIF":2.3,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141438804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research priorities in veterinary palliative care 兽医姑息治疗的研究重点。
IF 2.3 2区 农林科学
Veterinary journal Pub Date : 2024-06-20 DOI: 10.1016/j.tvjl.2024.106184
J. Maria da Costa , Teresa Guerra Barroso , Joana Correia Prata
{"title":"Research priorities in veterinary palliative care","authors":"J. Maria da Costa ,&nbsp;Teresa Guerra Barroso ,&nbsp;Joana Correia Prata","doi":"10.1016/j.tvjl.2024.106184","DOIUrl":"10.1016/j.tvjl.2024.106184","url":null,"abstract":"<div><p>Veterinary palliative care consists of end-of-life care of companion animals suffering from terminal or life-limiting diseases. Despite the growing need for veterinary palliative care, little research has been conducted on this topic. This perspective intends to provide an overview of the existing concerns and identify knowledge gaps to motivate further research. As a result, three main areas of research have been identified, namely: i) how to provide palliative care considering welfare implications of different diseases (e.g., pain management); ii) what can be considered a “good death”, depending on the individual situation of the animal and its caregiver; iii) how to support caregivers’ needs during their companion animal’s end-of-life. Therefore, veterinary palliative care involves medical, ethical, and sociological considerations that should be addressed through guidelines and training.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106184"},"PeriodicalIF":2.3,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324001230/pdfft?md5=18c35d1242bcb10d140d0309f5927d51&pid=1-s2.0-S1090023324001230-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracolumbar hydrated nucleus pulposus extrusion and intervertebral disc extrusion in dogs: Comparison of clinical presentation and magnetic resonance imaging findings 狗的胸腰椎水合髓核挤压和椎间盘挤压:临床表现与磁共振成像结果的比较。
IF 2.3 2区 农林科学
Veterinary journal Pub Date : 2024-06-19 DOI: 10.1016/j.tvjl.2024.106178
E. Alcoverro , I. Schofield , S. Spinillo , A. Tauro , M. Ruggeri , M. Lowrie , S.A. Gomes
{"title":"Thoracolumbar hydrated nucleus pulposus extrusion and intervertebral disc extrusion in dogs: Comparison of clinical presentation and magnetic resonance imaging findings","authors":"E. Alcoverro ,&nbsp;I. Schofield ,&nbsp;S. Spinillo ,&nbsp;A. Tauro ,&nbsp;M. Ruggeri ,&nbsp;M. Lowrie ,&nbsp;S.A. Gomes","doi":"10.1016/j.tvjl.2024.106178","DOIUrl":"10.1016/j.tvjl.2024.106178","url":null,"abstract":"<div><p>Thoracolumbar hydrated nucleus pulposus extrusion (TL-HNPE) is an increasingly recognised pathology with a substantial lack of literature describing its features. The aim of this retrospective case-control study was to analyse the clinical and magnetic resonance imaging (MRI) features of dogs with TL-HNPE compared to dogs affected with thoracolumbar intervertebral disc extrusion (TL-IVDE). Data from dogs diagnosed with TL-HNPE and TL-IVDE via MRI at two referral hospitals, were retrospectively collected and compared in terms of clinical signs and MRI features. Cases diagnosed with TL-IVDE were deemed controls. The MRI features of the affected IVD space, herniated IVD material, affected overlying spinal cord and local epaxial musculature were evaluated for each group. Fifty-one cases with TL-HNPE and 105 randomly selected cases of TL-IVDE were included. Several signalment and neurological signs were identified as statistically distinct between groups in univariate analysis. Multivariate analysis identified that dogs affected with TL-HNPE were typically older, less likely to be chondrodystrophic (62.2 % vs. 91 %), more frequently experiencing a peracute onset (90.2 % vs. 61.9 %) often attributed to a suspected trauma linked with exercise (37.3 % vs. 10.5 %), being less frequently progressive (41.2 % vs. 86.5 %) and with herniated disc material less frequently lateralised (72.6 % vs. 89.5 %) than cases with TL-IVDE. MRI-identifiable intervertebral disc degeneration was found in every TL-IVDE case but only in 60 % of TL-HNPE cases. TL-HNPEs were associated to significantly less spinal cord compression and less hyperalgesia than TL-IVDE.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106178"},"PeriodicalIF":2.3,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141437615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early Detection of Sub-clinical Mastitis in Murrah Buffaloes through Udder Thermogram Analysis during the Natural Progression of Infection 在感染的自然发展过程中,通过乳房热图分析及早发现穆拉水牛的亚临床乳腺炎。
IF 2.3 2区 农林科学
Veterinary journal Pub Date : 2024-06-18 DOI: 10.1016/j.tvjl.2024.106176
S.L. Gayathri, M. Bhakat , T.K. Mohanty
{"title":"Early Detection of Sub-clinical Mastitis in Murrah Buffaloes through Udder Thermogram Analysis during the Natural Progression of Infection","authors":"S.L. Gayathri,&nbsp;M. Bhakat ,&nbsp;T.K. Mohanty","doi":"10.1016/j.tvjl.2024.106176","DOIUrl":"10.1016/j.tvjl.2024.106176","url":null,"abstract":"<div><p>Mastitis is a global production disease that needs an intelligent solution to tackle effectively. Infrared Thermography (IRT) is a non-invasive technology that could be incorporated into routine day-to-day farm activities to monitor the health status of the animals. In this study, the udder health status was routinely monitored for 30 days among 41 Murrah buffaloes via IRT and the California Mastitis Test (CMT). Further, somatic cell count (SCC), microbial identification, and milk quality parameters were also estimated for representative samples. The thermal imaging data obtained was tabulated and back propagated from the 0th day to the −10th day and front propagated from the 0th day to +10th day for all the udder quarters. Results revealed that on the 0th day, the mean of udder skin surface temperature (USST) and teat skin surface temperature (TSST) showed a difference (p &lt; 0.05) in the sub-clinical mastitis (SCM) and clinical mastitis (CM) affected quarters to the healthy quarters, and their degree of difference was the highest. The indication of infection was signaled during the −9th to −5th day to <sup>th</sup>e 0th day in SCM and CM cases. There was a steep increment in the temperature from −2nd and −1st day to the 0th day of infection. Sometimes, some quarters show an increment in temperature due to mastitis during morning hours but recover by evening milking due to the animal's innate immune system. Thus, the initiation period in which the udder gets assaulted is crucial in the early assessment of SCM by monitoring temperature change using IRT.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106176"},"PeriodicalIF":2.3,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insights into the gut-kidney axis and implications for chronic kidney disease management in cats and dogs 洞察肠道-肾轴及其对猫狗慢性肾病管理的影响。
IF 2.3 2区 农林科学
Veterinary journal Pub Date : 2024-06-17 DOI: 10.1016/j.tvjl.2024.106181
Stacie Summers , Jessica Quimby
{"title":"Insights into the gut-kidney axis and implications for chronic kidney disease management in cats and dogs","authors":"Stacie Summers ,&nbsp;Jessica Quimby","doi":"10.1016/j.tvjl.2024.106181","DOIUrl":"10.1016/j.tvjl.2024.106181","url":null,"abstract":"<div><p>Chronic kidney disease (CKD) in cats and dogs presents significant clinical challenges, with emerging research highlighting the pivotal role of the gut-kidney axis in its pathogenesis and management. Gut dysbiosis, characterized by alterations in the gut microbiome composition and function, contributes to microbial dysmetabolism of key nutrients causing uremic toxin accumulation and disruptions in amino acid, bile acid and fatty acid profiles. These disturbances in turn exacerbate renal dysfunction and systemic inflammation. Recent research in veterinary medicine, particularly in cats, supports the gut microbiome and microbial-derived metabolites as novel therapeutic targets. Potential therapeutic strategies targeting the gut microbiome and microbial dysmetabolism, including dietary management, probiotics, adsorbents, and addressing constipation, offer promising avenues for intervention to restore metabolic balance and preserve renal function. This review highlights the microbial influence on renal health and focuses on potential therapeutic strategies available to veterinarians to optimize the management of CKD in cats and dogs.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106181"},"PeriodicalIF":2.3,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324001205/pdfft?md5=74f4d843441c9455edb38e169d8460fb&pid=1-s2.0-S1090023324001205-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141427746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancement of systemic virus-specific T lymphocyte responses in pigs supplemented with algae-derived β-glucan 增强补充藻源β-葡聚糖的猪的全身病毒特异性T淋巴细胞反应。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-17 DOI: 10.1016/j.tvjl.2024.106182
SH.B. Chuaychu , C. Sirisereewan , N. Techakriengkrai , P. Tummaruk , R. Thanawongnuwech , T. Nedumpun
{"title":"Enhancement of systemic virus-specific T lymphocyte responses in pigs supplemented with algae-derived β-glucan","authors":"SH.B. Chuaychu ,&nbsp;C. Sirisereewan ,&nbsp;N. Techakriengkrai ,&nbsp;P. Tummaruk ,&nbsp;R. Thanawongnuwech ,&nbsp;T. Nedumpun","doi":"10.1016/j.tvjl.2024.106182","DOIUrl":"10.1016/j.tvjl.2024.106182","url":null,"abstract":"<div><p>Algae-derived β-glucan has been widely used as a feed additive in the swine industry. The supplementation of β-glucan aims to improve growth performance and modulate the immunity of pigs. However, the potential effects of supplementing β-glucan from algae on immune responses in pigs—specifically antigen-specific immunity—must be determined. In this study, the effects of algae-derived β-glucan supplementation on growth performance, virus neutralising antibody and virus-specific T lymphocytes responses were investigated in pigs. Piglets (n=112 per treatment) were assigned to three treatments including non-supplemented group (control), β-glucan 100 g/ton supplemented group (BG100), and β-glucan 200 g/ton supplemented group (BG200).</p><p>In this study, production performance of pigs was not found to be different between the experimental groups. Pigs supplemented with β-glucan exhibited high levels of classical swine fever virus (CSFV)-specific producing T lymphocytes and neutralising antibody titer, compared to the control group. Interestingly, supplementation of β-glucan significantly enhanced porcine reproductive and respiratory syndrome virus (PRRSV)-specific interferon-gamma (IFN-γ) producing T lymphocytes, including CD4<sup>+</sup>, CD8<sup>+</sup>, and CD4<sup>+</sup>CD8<sup>+</sup> T lymphocyte subpopulations. Moreover, PRRS modified live vaccine (MLV) viremia was reduced in earlier for β-glucan-supplemented pigs compared to the control group. The findings indicate that the algae-derived β-glucan possesses biological potential as an immunomodulatory substance to enhance antiviral immunity, which may contribute to disease resistance in pigs.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106182"},"PeriodicalIF":2.2,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141427744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring hoof horn haemorrhage in heifers: A history 测量小母牛的蹄角出血:一段历史。
IF 2.3 2区 农林科学
Veterinary journal Pub Date : 2024-06-17 DOI: 10.1016/j.tvjl.2024.106183
Richard Laven, Linda Laven
{"title":"Measuring hoof horn haemorrhage in heifers: A history","authors":"Richard Laven,&nbsp;Linda Laven","doi":"10.1016/j.tvjl.2024.106183","DOIUrl":"10.1016/j.tvjl.2024.106183","url":null,"abstract":"<div><p>Understanding the aetiology and pathogenesis of claw-horn disease (CHD) is essential for developing prevention/treatment programmes. Haemorrhages in the hoof horn (i.e. white line/sole haemorrhages) are an important part of the pathogenesis of CHD, being precursors to and predictors of lesions such as white-line disease and sole ulcer. Understanding haemorrhage development can provide useful information about the aetiology and pathogenesis of CHD. The development of hoof horn haemorrhages is best studied in cattle without previous claw-horn damage, as previous history of damage can markedly alter the hoof’s response to stressors. Since the early 1990s, many prospective studies of the risk factors associated with CHD have been undertaken in late pregnant and early lactation heifers, which have a low risk of having had CHD but which are exposed to the same risk factors as lactating cows. Those studies have used a range of methods to assess hoof horn haemorrhages, with the principal focus, particularly initially (but also more recently), being on measuring lesion severity. However, as the science developed it became clear that measuring lesion extent was also important and that combining severity and extent in a single measure was the best approach to assess hoof horn haemorrhages. Studies of hoof horn haemorrhage in heifers have significantly increased our understanding of CHD, demonstrating the importance of housing and the relative lack of importance of post-calving nutrition. Most importantly, they have shown the importance of parturition as a risk factor for CHD, and how parturition interacts with other risk factors to accentuate their effect. The use of such studies has decreased in recent years, despite recent research showing that we still have much to learn from prospective studies of hoof horn haemorrhages in heifers.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106183"},"PeriodicalIF":2.3,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324001229/pdfft?md5=1066ce0166bfbc8849d73e5f3d441334&pid=1-s2.0-S1090023324001229-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141427747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the dynamics of human scent in forensic canine analysis: Factors shaping identification accuracy 探索法医犬分析中人类气味的动态:影响识别准确性的因素。
IF 2.3 2区 农林科学
Veterinary journal Pub Date : 2024-06-17 DOI: 10.1016/j.tvjl.2024.106180
M.N. Zahid , N.A. Qaed , Q. Abbas , S. Mustafa , S. Al-Thawadi
{"title":"Exploring the dynamics of human scent in forensic canine analysis: Factors shaping identification accuracy","authors":"M.N. Zahid ,&nbsp;N.A. Qaed ,&nbsp;Q. Abbas ,&nbsp;S. Mustafa ,&nbsp;S. Al-Thawadi","doi":"10.1016/j.tvjl.2024.106180","DOIUrl":"10.1016/j.tvjl.2024.106180","url":null,"abstract":"<div><p>Using specially trained canines in forensic analysis to identify individual human scents is a well-established method, capitalizing on dogs' exceptional olfactory abilities. This study investigates the survival of human scent under extreme weather conditions in the Kingdom of Bahrain. Five experienced German Shepherd police dogs, trained for human scent tracking, participated in the experiments. The study was conducted during Bahrain's hot summer season, characterized by high temperatures, high humidity, and occasional strong winds. Three common surfaces—sand, grass, and asphalt—were selected to represent scenarios where human scent might be detected.</p><p>The findings revealed that human scent persisted for approximately 8–11 hours on sand and grass but only 1–3 hours on asphalt, highlighting the impact of surface type on scent survival. The research also examined the effect of temperature on scent survival, testing at three different temperatures: 30°C, 40°C, and 50°C. The results demonstrated that scent durability varied across types of articles and temperature conditions. For instance, at 30°C, human scent remained detectable for up to 93 days on leather but only 27–28 days on silk cloth. At 40°C, leather allowed the scent to last 64–65 days, while wood surfaces had the shortest duration. The scent lasted 37–39 days on jeans cloth at a temperature of 50°C but only 3–4 days on wood. The data gathered can be beneficial for forensic investigations in semi-desert areas involving canine olfaction, offering guidance on the timing and likelihood of scent detection.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106180"},"PeriodicalIF":2.3,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141427745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re: Re: Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs 回复Re:犬用抗神经生长因子单克隆抗体贝丁维单抗的实验室安全性评估
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-15 DOI: 10.1016/j.tvjl.2024.106175
Adam Werts , Douglas Reece , Tony Simon , Phaedra Cole
{"title":"Re: Re: Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs","authors":"Adam Werts ,&nbsp;Douglas Reece ,&nbsp;Tony Simon ,&nbsp;Phaedra Cole","doi":"10.1016/j.tvjl.2024.106175","DOIUrl":"10.1016/j.tvjl.2024.106175","url":null,"abstract":"<div><p>In their letter to the editor, <span>Farrell et al., (2024)</span> presented questions related to canine joint health after treatment with the anti-Nerve Growth Factor (NGF) monoclonal antibody (mAb) bedinvetmab, which was presented as a component of a non-clinical laboratory safety assessment published in <span>Krautmann et al., (2021)</span>. Their questions appear to have stemmed from an anti-NGF mAb developed for the treatment of osteoarthritis in humans (tanezumab; <span>FDA, 2021</span>) which in 2021 failed to achieve marketing approval due to an unfavorable benefit: risk profile, primarily due to a syndrome called Rapidly Progressive Osteoarthritis (RPOA) which occurred more commonly in treatment groups when compared to controls. <span>Farrell et. al. (2024)</span> have posed questions on radiographic and histopathologic bone findings from studies included in <span>Krautmann, et al., (2021)</span> and communicated in the FDA’s Freedom of Information summary for Librela (<span>FDA, 2023</span>). These findings have previously been determined to be incidental and not bedinvetmab-associated. To address the questions posed, it is important to briefly define RPOA and summarize the syndrome in humans, review why the bone/joint findings in bedinvetmab safety studies in dogs are not indicative of RPOA or an RPOA-like condition, provide an update on joint health after use of bedinvetmab since market approval (&gt;3 years in some markets), and summarize why Zoetis, the manufacturer of Librela, has confidence in joint safety after use of bedinvetmab in dogs.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106175"},"PeriodicalIF":2.2,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S109002332400114X/pdfft?md5=9eb636c06fa2ac3d44be184af98c8bdc&pid=1-s2.0-S109002332400114X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141401948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic value of power doppler ultrasonography for equine superficial digital flexor tendon injury in thoroughbred racehorses 功率多普勒超声波对纯血赛马马掌屈肌腱损伤的预后价值。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-14 DOI: 10.1016/j.tvjl.2024.106179
N. Tamura , E. Yoshihara , K. Seki , N. Mae , K. Kodaira , M. Iimori , Y. Yamazaki , H. Mita , S. Urayama , T. Kuroda , M. Ohta , Y. Kasashima
{"title":"Prognostic value of power doppler ultrasonography for equine superficial digital flexor tendon injury in thoroughbred racehorses","authors":"N. Tamura ,&nbsp;E. Yoshihara ,&nbsp;K. Seki ,&nbsp;N. Mae ,&nbsp;K. Kodaira ,&nbsp;M. Iimori ,&nbsp;Y. Yamazaki ,&nbsp;H. Mita ,&nbsp;S. Urayama ,&nbsp;T. Kuroda ,&nbsp;M. Ohta ,&nbsp;Y. Kasashima","doi":"10.1016/j.tvjl.2024.106179","DOIUrl":"10.1016/j.tvjl.2024.106179","url":null,"abstract":"<div><p>The potential value of hypervascularity detected with power Doppler ultrasonography (PDU) within equine superficial digital flexor tendon (SDFT) as a prognostic factor of SDFT injury is not clear. The purpose of this study was to test the hypothesis that hypervascularity within SDFT is one of the risk factors for subsequent severe SDFT injury and to evaluate the prognostic value. A prospective cohort study of 97 Thoroughbred racehorses without any clinical signs of SDFT injury was conducted. Six variables of age, body weight, sex, the cross-sectional area of SDFT, PDU signal within SDFT and experience of steeplechase were assessed for the possibility of risk factors of subsequent SDFT injury in follow-up period of 1 year. Multivariable logistic regression analyses were used for assessment of the odds ratios (ORs) and 95 % confidence intervals (CIs) of SDFT injury. Multivariable logistic regression analysis revealed that the PDU signal within SDFT was a risk factor for the development of SDFT injury in follow-up period (<em>P</em> = 0.017). The adjusted OR of SDFT injury was significantly higher in PDU positive group than in PDU negative group (OR 3.17, 95 % CIs 1.20–8.35). Although further studies are required, these results would be useful for early detection and/or prevention of development for clinical severe SDFT injury.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106179"},"PeriodicalIF":2.2,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信