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Exploring the most common lesion of Australian farmed saltwater crocodile (Crocodylus porosus) belly skin in the Northern Territory 探索北领地澳大利亚养殖咸水鳄(Crocodylus porosus)腹部皮肤最常见的病变。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-13 DOI: 10.1016/j.tvjl.2024.106174
Rhiannon L. Slape, Natalie L. Milic
{"title":"Exploring the most common lesion of Australian farmed saltwater crocodile (Crocodylus porosus) belly skin in the Northern Territory","authors":"Rhiannon L. Slape,&nbsp;Natalie L. Milic","doi":"10.1016/j.tvjl.2024.106174","DOIUrl":"10.1016/j.tvjl.2024.106174","url":null,"abstract":"<div><p>This is the first descriptive study to characterise and identify the most common lesions on harvested Australian saltwater crocodiles (<em>Crocodylus porosus)</em>. 88 skins were examined over a 17-month period as part of normal farming practices, 2901 lesions identified, with scale location, location of the lesion on the scale, and characteristics (contour, keratin normality, translucency and colour) recorded. The study determined that linear lesions accounted for 68.25 % of lesions followed by foci lesions 17.24 %. Lesions were distributed on the upper proportion of the belly skin (77.8 %) and along the midline (72 %). The most common lesion identified was a single translucent linear lesion across the scale that otherwise appeared normal (58.95 %). While there is extensive research into pathogenic agents, further research is recommended to explore further causation of linear lesions, and factors that may contribute to their prevention. Given the subjective nature of crocodile skin grading, it is recommended future research into lesions is required to ensure the sustainability and profitability of the industry.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106174"},"PeriodicalIF":2.2,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141327864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobials administration, treatment outcome and bacterial susceptibility in canine pyometra cases subjected to ovariohysterectomy 接受卵巢切除术的犬脓子宫病例的抗菌药物用量、治疗效果和细菌敏感性。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-10 DOI: 10.1016/j.tvjl.2024.106157
A. Bertero , M. Corrò , E. Spagnolo , T. Nervo , A. Rota
{"title":"Antimicrobials administration, treatment outcome and bacterial susceptibility in canine pyometra cases subjected to ovariohysterectomy","authors":"A. Bertero ,&nbsp;M. Corrò ,&nbsp;E. Spagnolo ,&nbsp;T. Nervo ,&nbsp;A. Rota","doi":"10.1016/j.tvjl.2024.106157","DOIUrl":"10.1016/j.tvjl.2024.106157","url":null,"abstract":"<div><p>Pyometra is a bacterial uterine infection that frequently affects intact older bitches. The treatment of choice is ovariohysterectomy, often associated with perioperative antimicrobial therapy. The aim of this retrospective investigation was to evaluate the antibiotic choice at different administration times (pre-surgery, at surgery/during hospitalization, and post-surgery) against complications and outcomes, considering the susceptibility profile of bacteria.</p><p>The medical records of 51 bitches referred to the Veterinary Teaching Hospital of the University of Turin (January 2021-November 2023) and subjected to ovariohysterectomy and bacteriological examination (bacterial culture and susceptibility tests) of the uterine exudate, were analysed. All animals had a positive outcome without surgical site infections, with a longer hospitalization time in case of peritonitis or sepsis; antimicrobials were administered for an average of 7 days. Comparing the susceptibility of the isolated bacteria towards the antimicrobials administered before, during and after surgery, complete efficacy was observed in 42 %, 46 % and 50 % of cases, respectively. In addition, 5/16 peritonitis cases were treated with an <em>in vitro</em> ineffective antimicrobial, and 30 % of the bitches never received a fully effective antibiotic, according to susceptibility tests using the minimum inhibitory concentration method (MIC). Cephazolin resulted the best option for <em>Escherichia coli</em>, the most frequently isolated bacterium. Our study confirms that pyometra has a good prognosis following ovariohysterectomy and antibiotic administration. Monitoring the clinical evolution without changing the antibiotic according to bacterial susceptibility could represent the right choice in uncomplicated cases. Evaluation of outcomes without postoperative antibacterial treatment or with a shorter course would be another topic worth investigating, with the aim to judiciously reduce the use of antibiotics.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106157"},"PeriodicalIF":2.2,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324000960/pdfft?md5=0f3042bd2507c968bc0e68e6f61b51f7&pid=1-s2.0-S1090023324000960-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141311811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of a continuous passive motion assistive device in dogs following stifle surgery 评估狗跗关节手术后的连续被动运动辅助装置。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-05 DOI: 10.1016/j.tvjl.2024.106160
A. Erazo , K.R. Pinto , Y. Choi , S.B. Ko
{"title":"Assessment of a continuous passive motion assistive device in dogs following stifle surgery","authors":"A. Erazo ,&nbsp;K.R. Pinto ,&nbsp;Y. Choi ,&nbsp;S.B. Ko","doi":"10.1016/j.tvjl.2024.106160","DOIUrl":"10.1016/j.tvjl.2024.106160","url":null,"abstract":"<div><p>Canine rehabilitation optimizes recovery and the quality of life in dogs with musculoskeletal conditions or after surgery. Achieving proper range of motion (ROM) is vital post-stifle surgery, often accomplished through manual therapy and active exercises. We investigated the mechanical performance of a continuous passive motion (CPM) device for dogs and its potential use in canine rehabilitation therapy.</p><p>In the ethical review process, our research was accepted to be evaluated in a sample of four dogs that had undergone left stifle surgery. Each dog underwent four sessions with the device at three different speeds. Results showed the device replicated extension angles close to goniometer measurements used in manual therapy. Flexion was also achieved, but not to the same extent. A force threshold stopped the device, avoiding discomfort in dogs with restricted ROM. Dog-specific factors like body position, opposition to movement, limb size, stage of recovery, haircoat, and discomfort, appeared to influence device operation. Mechanical improvements to allow for enhanced flexion are recommended in future CPM device designs, including a resistance threshold that could be adjusted for individual dogs and stages of healing. This study serves as a foundation for future advancements in canine rehabilitation systems. A canine CPM device may provide an affordable option to improve ROM. This could be beneficial for dog owners, who may not be comfortable with manual therapy, to assist with home rehabilitation exercises.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106160"},"PeriodicalIF":2.2,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324000996/pdfft?md5=5c39970930dbc8b4977a627df6964060&pid=1-s2.0-S1090023324000996-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytotoxicity of local anaesthetics and protective effects of platelet rich plasma on equine tenocytes: An in vitro study 局部麻醉剂的细胞毒性和富血小板血浆对马腱鞘细胞的保护作用:体外研究。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-05 DOI: 10.1016/j.tvjl.2024.106159
Alessia Tognoloni , Martina Pellegrini , Alessandra Di Salvo , Monica Sforna , Monica Cagiola , Matteo Seccaroni , Sara Nannarone , Francesca Beccati , Maria Chiara Pressanto , Antonio Di Meo , Elisabetta Chiaradia
{"title":"Cytotoxicity of local anaesthetics and protective effects of platelet rich plasma on equine tenocytes: An in vitro study","authors":"Alessia Tognoloni ,&nbsp;Martina Pellegrini ,&nbsp;Alessandra Di Salvo ,&nbsp;Monica Sforna ,&nbsp;Monica Cagiola ,&nbsp;Matteo Seccaroni ,&nbsp;Sara Nannarone ,&nbsp;Francesca Beccati ,&nbsp;Maria Chiara Pressanto ,&nbsp;Antonio Di Meo ,&nbsp;Elisabetta Chiaradia","doi":"10.1016/j.tvjl.2024.106159","DOIUrl":"10.1016/j.tvjl.2024.106159","url":null,"abstract":"<div><p>Local anaesthetics (LAs) can have detrimental effects on rat, bovine, canine, and human tendon tissues and cells. Currently, there has been no available data on the impact of these drugs on equine tenocytes. Even if LA injection for managing painful tendon conditions in horses is limited, it is usually used via intra-articular, intrasynovial, perineural, and intrathecal as well as for lameness examinations. In this <em>in vitro</em> study, the cytotoxic effects of LAs, including lidocaine, mepivacaine, and bupivacaine on equine tenocytes, in the presence and absence of platelet rich plasma (PRP), were investigated. PRP accelerates tissue healing and can exert cytoprotective effects on different cell types exposed to different stressful conditions, including drugs. Results indicated that the exposure to LAs significantly reduced tenocytes viability in dose- and time-dependent manners while PRP was able to counteract their cytotoxic effects. Furthermore, microscopy and flow cytometry analyses revealed apoptosis and necrosis in equine tenocytes exposed to these drugs, that were both reduced when PRP was in the medium. These findings highlight the importance of considering the tenocyte toxicity associated with intrathecal and intraneural LA injections, as they might affect tenocytes or reduce the efficacy of associated therapies. Moreover, this study also highlights the protective effects of PRP, which could make LA injections safer.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106159"},"PeriodicalIF":2.2,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324000984/pdfft?md5=1af312e34c5f9ae674f48e35a49b3b5a&pid=1-s2.0-S1090023324000984-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fibronectin type III domain-containing protein 5 (FNDC5)-like immunoreactivity and mRNA abundance in domestic animal tissues 家畜组织中的纤连蛋白 III 型域含蛋白 5 (FNDC5)-like 免疫活性和 mRNA 丰度。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-05 DOI: 10.1016/j.tvjl.2024.106161
E. Lai, J. Sands, S. Unniappan
{"title":"Fibronectin type III domain-containing protein 5 (FNDC5)-like immunoreactivity and mRNA abundance in domestic animal tissues","authors":"E. Lai,&nbsp;J. Sands,&nbsp;S. Unniappan","doi":"10.1016/j.tvjl.2024.106161","DOIUrl":"10.1016/j.tvjl.2024.106161","url":null,"abstract":"<div><p>Irisin is a 112-amino acid peptide hormone that is cleaved from fibronectin type III domain-containing protein 5 (FNDC5), a type I transmembrane protein abundantly found in muscle tissue. Irisin is a putative mediator of the benefits of exercise, neuroprotection, bone growth, and cardiac health. However, few studies have focused on irisin in domestic animals. Further, whether processed irisin is detectable in domestic animal tissues remains uncertain. To address this, we determined FNDC5 mRNA and protein concentration in anatine (duck) and porcine (pig) skeletal muscle, and in equine (horse), swine, and anatine serum samples. RT-PCR analysis identified FNDC5 mRNA in all pig and duck skeletal muscle samples. An approximately 25 kDa band representing FNDC5 was detected in both pig and duck skeletal muscle. Fluorescence immunohistochemistry using a rabbit monoclonal FNDC5/irisin primary antibody and a goat polyclonal anti-rabbit secondary antibody localized FNDC5/irisin-like immunoreactivity in both the glandular and muscular regions of pig stomach. FNDC5/irisin-like immunoreactivity was also identified in horse, pig, and duck serum using a multispecies irisin ELISA. The average values of irisin-like immunoreactivity were 13.7 (duck), 15.4 (horse), and 7.0 (pig) ng/mL in samples tested. Our results support the presence of irisin precursor in several domestic animals. Processed irisin, however, was not detectable. Further studies are required to validate reliable tools to detect and quantify processed irisin in domestic animals.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106161"},"PeriodicalIF":2.2,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S109002332400100X/pdfft?md5=335eaf19ec091eb4b309236758e36cb3&pid=1-s2.0-S109002332400100X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous pulmonary interstitial emphysema, pneumomediastinum and cervical subcutaneous emphysema secondary to the Macklin effect in dogs with no clinical signs: 12 cases 无临床症状的狗继发于麦克林效应的自发性肺间质气肿、气胸和颈部皮下气肿:12 例。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-05 DOI: 10.1016/j.tvjl.2024.106158
J. Guillem, W. Humphreys
{"title":"Spontaneous pulmonary interstitial emphysema, pneumomediastinum and cervical subcutaneous emphysema secondary to the Macklin effect in dogs with no clinical signs: 12 cases","authors":"J. Guillem,&nbsp;W. Humphreys","doi":"10.1016/j.tvjl.2024.106158","DOIUrl":"10.1016/j.tvjl.2024.106158","url":null,"abstract":"<div><p>Pneumomediastinum denotes the presence of gas within the mediastinum and generally occurs by leakage of air from an aerated viscus that traverses or abuts the mediastinal plane. The Macklin effect has been described in several veterinary studies and describes gas tracking along the perivascular interstitium following alveolar rupture causing interstitial emphysema, pneumomediastinum and subsequently cervical subcutaneous emphysema. This retrospective case series describes incidental spontaneous pulmonary interstitial emphysema, pneumomediastinum and cervical subcutaneous emphysema secondary to the Macklin effect in dogs with no related clinical signs. Twelve dogs were identified from the author’s institution, of which 75 % were Sighthounds (Greyhounds, Whippets or Lurchers). Pulmonary interstitial emphysema had a predominantly paravascular distribution, although in some cases a parabronchial distribution was also identified. We conclude that incidental pulmonary interstitial emphysema, pneumomediastinum and secondary cervical subcutaneous emphysema can be incidental, presumed secondary to the Macklin effect and that Sighthound breeds may be overrepresented.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106158"},"PeriodicalIF":2.2,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324000972/pdfft?md5=68131984673f90b0c207e966a718ed13&pid=1-s2.0-S1090023324000972-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of casozepine administration on stress in dogs during a veterinary examination – A randomized placebo-controlled trial 随机安慰剂对照试验:服用卡索西泮对狗在兽医检查过程中的应激反应的影响。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-04 DOI: 10.1016/j.tvjl.2024.106148
M. Schroers, A. Juhasz, Y. Zablotski, A. Meyer-Lindenberg
{"title":"Effect of casozepine administration on stress in dogs during a veterinary examination – A randomized placebo-controlled trial","authors":"M. Schroers,&nbsp;A. Juhasz,&nbsp;Y. Zablotski,&nbsp;A. Meyer-Lindenberg","doi":"10.1016/j.tvjl.2024.106148","DOIUrl":"10.1016/j.tvjl.2024.106148","url":null,"abstract":"<div><p>The aim of the study was to investigate the stress-reducing effect of a casozepine before a veterinary examination in dogs. It should be examined whether the dogs are less stressed during a standardized veterinary examination after an oral application of casozepine over 2 days and whether the administration has an influence on the salivary concentrations of the stress hormones vasopressin and cortisol. Across the study group (<em>n</em>=36), a significantly lower stress score (<em>P</em>=0.0026) and lower mean (<em>P</em>=0.01) and maximum (<em>P</em>=0.024) pulse rates were seen at follow-up after casozepine administration, in contrast to the placebo group (<em>n</em>=26). Salivary vasopressin concentrations increased during follow-up in the placebo group (<em>P</em>=0.04), whereas they remained the same in the casozepine group. Cortisol concentrations increased during follow-up in the casozepin group (<em>P</em>=0.01). The results indicate that although dogs in both groups remained excited at follow-up, short-term casozepine administration before a veterinary visit had a weak stress-reducing effect in dogs based on subjective stress scoring and pulse rate.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106148"},"PeriodicalIF":2.2,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S109002332400087X/pdfft?md5=da1a96ee87a1ab596be9c7c22d2ed899&pid=1-s2.0-S109002332400087X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurological consequences after portosystemic shunt attenuation in cats: A meta-analysis study 猫门静脉分流术后的神经系统后果:一项荟萃分析研究。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-03 DOI: 10.1016/j.tvjl.2024.106150
Sepide Mohammadi , Niusha Pahlevaninezhad , Parastoo Valavi , Dornaz Mehinparvar Irani , Farzane Shams , Pardis Mohamadi , Mohammad Jokar , Arman Abdous
{"title":"Neurological consequences after portosystemic shunt attenuation in cats: A meta-analysis study","authors":"Sepide Mohammadi ,&nbsp;Niusha Pahlevaninezhad ,&nbsp;Parastoo Valavi ,&nbsp;Dornaz Mehinparvar Irani ,&nbsp;Farzane Shams ,&nbsp;Pardis Mohamadi ,&nbsp;Mohammad Jokar ,&nbsp;Arman Abdous","doi":"10.1016/j.tvjl.2024.106150","DOIUrl":"10.1016/j.tvjl.2024.106150","url":null,"abstract":"<div><p>Neurological symptoms that occur after treatment of portosystemic shunts, in cats, known as post-attenuation neurological signs (PANS) can be quite severe. This study seeks to analyze a better understanding of the neurological outcomes that result from reducing portosystemic shunts in felines and provide insights that could guide future clinical approaches and treatment strategies for congenital portosystemic shunts (CPSS).The research utilized the MOOSE Checklist as a guide. PubMed/MEDLINE, Web of Science ScienceDirect, Embase, Scopus, ProQuest, and Google Scholar were used. The study investigated diversity using variance, Cochran Q tests with Applied fixed effects, and random effects models. A meta-regression model identified contributors. Eggers test funnel plot and Beggs test for asymmetry addressed publication bias. 12 high-quality studies were discovered from 664 research papers. This research covered years, shunt morphology, and surgery. PANS occurred 38.9 % of the time in cats, while PAS occurred 20.2 %. The overall PANS mortality rate was 17 %, while PAS was 37.2 %. The complete ligation technique was most common in subgroup analysis. PANS occurrence ranged from 26.8 % to 56.5 % in cats with congenital extrahepatic portosystemic shunts The cause of PANS in cats is still unknown, and there is only limited evidence to justify the use of preventive antiepileptic medications such as levetiracetam. The treatment primarily aims to control neurologic symptoms, and the long-term outlook varies, with the potential for the reappearance of symptoms.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106150"},"PeriodicalIF":2.2,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Equus caballus papillomavirus Type 7 is a rare cause of equine penile squamous cell carcinomas Equus Caballus Papillomavirus Type 7 是马阴茎鳞状细胞癌的罕见病因。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-03 DOI: 10.1016/j.tvjl.2024.106155
John S. Munday , Cameron G. Knight , Christa J. Bodaan , Camille Codaccioni , Michael R. Hardcastle
{"title":"Equus caballus papillomavirus Type 7 is a rare cause of equine penile squamous cell carcinomas","authors":"John S. Munday ,&nbsp;Cameron G. Knight ,&nbsp;Christa J. Bodaan ,&nbsp;Camille Codaccioni ,&nbsp;Michael R. Hardcastle","doi":"10.1016/j.tvjl.2024.106155","DOIUrl":"10.1016/j.tvjl.2024.106155","url":null,"abstract":"<div><p>Penile squamous cell carcinomas (SCCs) are common, potentially life-threatening neoplasms of horses. They are well-recognized to be caused by Equus caballus papillomavirus (EcPV) type 2, although EcPV2 cannot be detected in all cases. A 23-year-old standardbred gelding developed multiple penile <em>in situ</em> and invasive SCCs that contained histological evidence of PV infection. By using both consensus and specific PCR primers, these lesions were found to contain EcPV7 DNA, but not DNA from EcPV2 or any other PV type. To determine how frequently EcPV7 is present in equine penile SCCs, specific primers were used to detect EcPV2 and EcPV7 in a series of 20 archived samples. EcPV7 was the only PV detected in one, both EcPV2 and 7 were detected in five, and only EcPV2 was detected in 14 SCCs. EcPV7 DNA was also detected in three of 10 archived oropharyngeal SCCs, although only as a co- infection with EcPV2. This is the first report of EcPV7 causing disease in horses. These results suggest EcPV7 could cause a subset of equine penile SCCs, and this is the first evidence that PV types other than EcPV2 can cause these neoplasms. The detection of EcPV7 in the oropharyngeal SCCs suggests a potential role of this PV type in the development of these SCCs. There were no clinical or histological features that differentiated lesions containing EcPV7 DNA from those containing EcPV2 DNA. If EcPV7 causes a proportion of equine penile SCCs, vaccines to prevent EcPV2 infection may not prevent all equine penile SCCs.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106155"},"PeriodicalIF":2.2,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324000947/pdfft?md5=03e52ac8dd433e358c34cb45a6b268d6&pid=1-s2.0-S1090023324000947-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative pain in dogs undergoing either laparoscopic or open ovariectomy 接受腹腔镜或开腹卵巢切除术的狗的术后疼痛。
IF 2.2 2区 农林科学
Veterinary journal Pub Date : 2024-06-02 DOI: 10.1016/j.tvjl.2024.106156
M. Fuertes-Recuero , I.A.Gómez de Segura , A.Sánchez López , M. Suárez-Redondo , S. Canfrán Arrabé , S. Penelo Hidalgo , J.C. Fontanillas-Pérez , G. Ortiz-Diez
{"title":"Postoperative pain in dogs undergoing either laparoscopic or open ovariectomy","authors":"M. Fuertes-Recuero ,&nbsp;I.A.Gómez de Segura ,&nbsp;A.Sánchez López ,&nbsp;M. Suárez-Redondo ,&nbsp;S. Canfrán Arrabé ,&nbsp;S. Penelo Hidalgo ,&nbsp;J.C. Fontanillas-Pérez ,&nbsp;G. Ortiz-Diez","doi":"10.1016/j.tvjl.2024.106156","DOIUrl":"10.1016/j.tvjl.2024.106156","url":null,"abstract":"<div><p>A prospective, quasi-experimental, clinical trial was performed to assess acute postoperative pain in healthy female dogs following elective ovariectomy by either laparoscopy (<em>n</em>=13) or laparotomy (<em>n</em>=14). Pain was assessed by both a veterinarian at the hospital, and by the owner once the patient was discharged. The Spanish version of the short form of the Glasgow Composite Measuring Pain Scale (CMPS-SF) was used. Pain scores were assessed by the veterinarian preoperatively and at 1, 2, 4, and 6 h after extubation, whilst owner-assessed scores were performed preoperatively and at postoperative days 0, 1, 2, 3, 5 and 7. Data were compared with Mann-Whitney-U test. Veterinarian-assessed CMPS-SF scores were different between both groups at all postoperative times but not at baseline, being below 6/24 in all dogs in the laparoscopy group, but equal to or greater than 6/24 in the laparotomy group at 1 h (<em>n</em>=12), and 4 h (<em>n</em>=4) (<em>P</em>&lt;0.001 and <em>P=</em>0.029, respectively). There were also differences in pain scores between both groups at 2 h (<em>P</em>=0.012) and 6 h (<em>P</em>=0.007), being below 6/24 in all of them. However, there were no differences in owner assessments between groups. In conclusion, ovariectomy performed by laparoscopy induced lower pain scores that were below the pain threshold set by the CMPS-SF during the first 6 h postoperatively. After discharge, and up to one week later, ongoing owner-assessed scores suggest no pain was induced with neither of the techniques. Owners were proactive allowing real-time pain assessment to be reported. The development and validation of instruments for acute pain assessment by owners is warranted, as these tools are currently lacking.</p></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"306 ","pages":"Article 106156"},"PeriodicalIF":2.2,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1090023324000959/pdfft?md5=ff212122584a6124bae78e924b7efa0f&pid=1-s2.0-S1090023324000959-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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