Veterinary journal最新文献

{"title":"Rabbit teeth serve as a calcium source for rabbits (Oryctolagus cuniculus).","authors":"J Mäkitaipale, H Opsomer, J-M Hatt, B Riond, M Clauss, A Liesegang","doi":"10.1016/j.tvjl.2024.106268","DOIUrl":"10.1016/j.tvjl.2024.106268","url":null,"abstract":"<p><p>Rabbits have hypselodont (ever-growing) teeth; dental growth constantly replaces dental tissue lost due to abrasion and attrition. It has been suggested that rabbits must have high mineral requirements, in particular for calcium, to fuel this constant tooth growth. However, this assumption ignores the fact that tooth wear represents finely ground tissue that is not lost to the body but swallowed during food processing. No studies exist regarding the possible recycling of dental enamel and dentin calcium. In this cross-over study, eight eight-months old intact female rabbits were fed with a complete pelleted diet containing either calcium carbonate/dicalcium phosphate (control) or ground rabbit teeth as calcium sources for 15 days each. After 11 days of adaptation, intake, urinary and faecal losses were quantified in a 4-day period in metabolism cages, and blood mineral levels were determined in a final blood sample. There were few relevant, significant differences between the treatments, with the exception of calcium digestibility (20 ±8% on the control vs. 33 ±6% on the tooth meal diet, P = 0.002) and total calcium retention (0.10 ±0.13 vs. 0.33 ±0.10g/d, P = 0.004). The results suggest that rabbits are well able to recycle the minerals from dental tissue lost during dental wear.</p>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":" ","pages":"106268"},"PeriodicalIF":2.3,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of peri- and postoperative antibiotic prophylaxis on surgical site infection in surgeries with elective antibiotic administration.","authors":"Nico Paeckel, Yuri Zablotski, Andrea Meyer-Lindenberg","doi":"10.1016/j.tvjl.2024.106267","DOIUrl":"https://doi.org/10.1016/j.tvjl.2024.106267","url":null,"abstract":"<p><p>The aim of this study was to investigate the effect of peri- and postoperative antimicrobial prophylaxis (AMP) on surgical site infection (SSI) in surgeries with elective antibiotic administration in a large university hospital with a high volume of people in the operating room. In this retrospective study, 1060 cats and dogs belonging to private owners were analysed for the occurrence of SSI over a period of almost 5 years, except during the COVID pandemic. Both the patient files were included, and the patient owners were contacted by questionnaire. The type of surgery, the use and type of AMP, as well as the occurrence, time, type and treatment of an SSI were documented. The overall SSI rate was 7.8% (66/841). The use of an AMP did not lead to a significant reduction in risk in any of the surgeries analysed. Postoperative continuation of antibiotic prophylaxis showed no significant difference compared to perioperative prophylaxis alone. When interpreting the results, the retrospective nature of the study should be considered, as well as the fact that some of the results are based on a survey of patient owners.</p>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":" ","pages":"106267"},"PeriodicalIF":2.3,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The problem that residual Mycobacterium bovis infection poses for the eradication of bovine tuberculosis","authors":"J. Wiseman ,&nbsp;J.P. Cassidy ,&nbsp;E. Gormley","doi":"10.1016/j.tvjl.2024.106266","DOIUrl":"10.1016/j.tvjl.2024.106266","url":null,"abstract":"<div><div>The dynamics of <em>Mycobacterium bovis</em> infection in cattle can influence the proportion of infected animals that are diagnosed by ante-mortem tests in routine bovine tuberculosis (bTB) surveillance and monitoring programmes. Although the current diagnostic tests based on cell-mediated or serological responses are imperfect, they are effective in diagnosing the majority of infected animals. However, the lack of perfect sensitivity and specificity also leads to failure to diagnose all infected animals leading to persistence of infection in herds. The terms residual, subclinical, latent and anergy have been used interchangeably to denote the presence of continued undiagnosed <em>M. bovis</em> infection within cattle herds, which ultimately hinders the eradication of bTB and imposes substantial financial burdens on farming communities and national economies. Epidemiological data suggests the existence of <em>M. bovis</em>-infected, but often undetected, cattle within herds that contribute to eradication failure. This has similarities with human tuberculosis, caused by <em>Mycobacterium tuberculosis</em>, where latent infection is defined as the persistence of viable but quiescent bacilli for extended periods in patients without clinical symptoms but with a detectable immune response to <em>M. tuberculosis</em> antigens. If a similar infection state exists in cattle infected with <em>M. bovis</em>, the persistence of such animals in disease-managed herds is unlikely to be common given that those found to have positive immune responses to <em>M. bovis</em> antigens are routinely culled to minimise future risk of transmission. Apart from contributing to the burden of herd infection, such residual infection without detection may also ‘seed’ recipient herds following animal movements, and potentially play an important role in the overall epidemiology of bTB as the prevalence of disease decreases and the attendant altered predictive value of the diagnostic tests result in a greater proportion of infected animals remaining undetected. This review examines how the different stages of <em>M. bovis</em> infection in cattle may contribute to the failure to diagnose infected animals using conventional testing methodologies and the attendant risk this poses in creating prolonged or recurrent herd breakdowns.</div></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"308 ","pages":"Article 106266"},"PeriodicalIF":2.3,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for antimicrobial usage and diseases in Dutch veal calf farms: A cross-sectional study","authors":"Panagiotis Mallioris ,&nbsp;Effrosyni Kritsi ,&nbsp;Peter Theeuwes ,&nbsp;Jaap A. Wagenaar ,&nbsp;Arjan Stegeman ,&nbsp;Lapo Mughini-Gras","doi":"10.1016/j.tvjl.2024.106263","DOIUrl":"10.1016/j.tvjl.2024.106263","url":null,"abstract":"<div><div>Antimicrobial use <strong>(AMU)</strong> is the main driver of antimicrobial resistance <strong>(AMR)</strong>. In the Netherlands, the veal calf sector was among the largest consumers of antimicrobials in Defined Daily Doses Animal <strong>(DDDA)</strong> for the year of 2022. As preventive use in Dutch livestock farms is forbidden since 2011, most AMU is due to the herd health status which is affected by the farm environment in which the conditions for diseases to spread are created. The aim of this study was to determine which disease etiologies for group treatments are associated with AMU in rosé starter veal calves, and which modifiable technical risk factors on farm are associated with those diseases and with total AMU. Cross-sectional data were collected from 36 Dutch rosé starter veal calf farms in the Netherlands in 2021 using a digital survey. Linear regression analysis showed that the main indications for AMU were respiratory infections, for which mainly tetracyclines and macrolides were used. Partial least squares regression analysis <strong>(PLS)</strong> revealed 13 on-farm practices associated with the number of group treatments for respiratory diseases and 19 with total AMU. Overlapping variables in both PLS models were related to regrouping of calves, micro-climate conditions, water access and weaning strategies. Overall, these features focused on improving animal welfare and nutrition during production and enhancing a farm’s internal and external biosecurity. This study identified opportunities for reducing AMU in rosé starter veal calf farms, which thereby could contribute to limiting AMR emergence and spread.</div></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"308 ","pages":"Article 106263"},"PeriodicalIF":2.3,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation and characterization of a mouse polyclonal antibody against the truncated ORFV113 recombinant protein of Orf virus","authors":"Shaobo Liang,&nbsp;Qinqin Long,&nbsp;Feng Pang","doi":"10.1016/j.tvjl.2024.106265","DOIUrl":"10.1016/j.tvjl.2024.106265","url":null,"abstract":"<div><div>Orf is a contagious zoonotic disease caused by Orf virus (ORFV), posing a threat to both animal and human health. The ORFV113 gene, located in the terminal variable region of the ORFV genome, has been demonstrated as a significant virulence gene, but its function remains largely unknown. In the study, we first amplified the truncated version of the ORFV113 gene (ORFV113t) by removing its transmembrane domain at the 5′ end. We then constructed the pET-32a-ORFV113t recombinant plasmid and expressed the truncated ORFV113 recombinant protein in <em>Escherichia coli</em> (<em>E.coli</em>). The purified ORFV113t fusion protein was used to immunize mice and generate a polyclonal antibody. This polyclonal antibody was subsequently used to detect the expression and subcellular localization of the ORFV113 protein. Additionally, virus neutralization test was utilized to determine the neutralizing titer of the polyclonal antibody. The results demonstrated that we successfully expressed the ORFV113t recombinant protein in a prokaryotic expression system and generated a mouse-derived polyclonal antibody targeting the ORFV113t recombinant protein with a titer of 1:204,800. This antibody exhibited specificity for detecting the ORFV113 protein expressed in both prokaryotic and eukaryotic cells. The ORFV113 protein was found to be localized in the cytoplasm of infected Lamb testis (LT) cells. Notably, the polyclonal antibody demonstrated neutralizing activity against ORFV in vitro, with a neutralizing titer of 1:32. The prepared mouse anti-ORFV113t protein polyclonal antibody can be utilized for further study on potential functions of the ORFV113 protein in viral pathogenesis.</div></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"308 ","pages":"Article 106265"},"PeriodicalIF":2.3,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antitumor effects of inhibitors of ERK and Akt pathways in canine histiocytic sarcoma cell lines","authors":"H. Sakuma ,&nbsp;H. Tomiyasu ,&nbsp;A. Tani ,&nbsp;Y. Goto-Koshino ,&nbsp;H. Tani ,&nbsp;K. Ohno ,&nbsp;H. Tsujimoto ,&nbsp;M. Bonkobara ,&nbsp;M. Okuda","doi":"10.1016/j.tvjl.2024.106264","DOIUrl":"10.1016/j.tvjl.2024.106264","url":null,"abstract":"<div><div>Canine histiocytic sarcoma (CHS) is characterized by aggressive biological behavior. In our previous study, ERK and Akt pathways were found to be activated in CHS tissues. Thus, the objective of this study was set to investigate the relationships between the activation status of these pathways and the proliferation of CHS cell lines by examining the effects of single and co-administrations of drugs targeting these pathways. First, we evaluated the changes in cell proliferations and the activations of ERK and Akt pathways after treatments with ERK and Akt-specific inhibitors in CHS cells. Then, these changes after treatments with dasatinib and trametinib were also examined in CHS cells. Inhibitors specific to ERK and Akt pathways successfully inhibited the respective pathways in CHS cell lines. It was also indicated that these pathways were associated with the regulations of proliferations of CHS cells, although the anti-proliferative effect was not necessarily observed by inhibition of Akt pathway alone. Dasatinib and trametinib also showed the inhibitions of Akt and ERK pathway activations, respectively, in CHS cells. However, the anti-proliferative effects of these drugs varied among CHS cell lines, and co-administration showed enhanced anti-proliferative effects in only a part of CHS cell lines. Further studies are needed to investigate the molecular mechanisms associated with the sensitivities to these molecular-targeted drugs in CHS cells.</div></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"308 ","pages":"Article 106264"},"PeriodicalIF":2.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary Cystatin B as a marker of acute kidney injury in cats","authors":"Hilla Chen ,&nbsp;Yochai Avital ,&nbsp;Sarah Peterson ,&nbsp;Zenhwa Ouyang ,&nbsp;Murthy Yerramilli ,&nbsp;Itamar Aroch ,&nbsp;Gilad Segev","doi":"10.1016/j.tvjl.2024.106262","DOIUrl":"10.1016/j.tvjl.2024.106262","url":null,"abstract":"<div><div>Diagnosing acute kidney injury (AKI) might be challenging due to lack of sensitive early markers. The objective of this study was to evaluate the diagnostic and prognostic utility of the urinary biomarker Cystatin B (uCysB) in cats with AKI. Seventy-six client-owned cats were included. Urine samples of healthy cats and cats with various urinary tract disease including urethral obstruction (UO), chronic kidney disease (CKD) and AKI, were collected. uCysB concentration was measured using a research sandwich format ELISA at IDEXX Laboratories, Inc. uCysB was different among groups (<em>P</em> &lt;0.001). uCysB was higher in the AKI (<em>P</em> &lt;0.001) and CKD (<em>P</em> =0.006) groups compared with controls [1052 ng/mL (range, 7–3858) and 112 ng/mL (range, 14–1370) vs. 22 ng/mL (range, 11–154), respectively]. Cats with AKI had higher uCysB compared with cats with CKD (<em>P</em> =0.001) or UO (<em>P</em> =0.004). Receiver operator characteristic curve (ROC) analysis of uCysB as an AKI predictor vs. controls had an area under the curve (AUC) of 0.92 (95 % CI, 0.84–1.0). An 84 ng/mL cutoff point corresponded to sensitivity and specificity of 90 % and 92 %, respectively. uCysB concentration was higher in AKI non-survivors compared with survivors (1572 ng/mL, range, 140–3858 vs. 584 ng/mL, range, 7–2803 respectively; <em>P</em> =0.004). ROC analysis of uCysB as an AKI outcome predictor had an AUC of 0.84 (95 % CI, 0.56–1.0), with an optimal cut-off point of 469 ng/mL, corresponding to sensitivity and specificity of 100 % and 75 % respectively. In conclusion, uCysB is a useful diagnostic and prognostic marker of AKI in cats.</div></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"308 ","pages":"Article 106262"},"PeriodicalIF":2.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monoclonal antibody development and antigenic epitope identification of infectious bursal disease virus VP5","authors":"Jinze Han ,&nbsp;Xinxin Niu ,&nbsp;Chengfei Ge ,&nbsp;Ziwen Wu ,&nbsp;Guodong Wang ,&nbsp;Mengmeng Huang ,&nbsp;Yulong Zhang ,&nbsp;Runhang Liu ,&nbsp;Mengmeng Xu ,&nbsp;Hangbo Yu ,&nbsp;Jingzhe Han ,&nbsp;Suyan Wang ,&nbsp;Yongzhen Liu ,&nbsp;Yuntong Chen ,&nbsp;Hongyu Cui ,&nbsp;Yanping Zhang ,&nbsp;Yulu Duan ,&nbsp;Xiaomei Wang ,&nbsp;Liuan Li ,&nbsp;Yulong Gao ,&nbsp;Xiaole Qi","doi":"10.1016/j.tvjl.2024.106254","DOIUrl":"10.1016/j.tvjl.2024.106254","url":null,"abstract":"<div><div>Infectious bursal disease (IBD) is an important immunosuppressive disease affecting chickens and is caused by infectious bursal disease virus (IBDV) infection. VP5 is a non-essential protein for IBDV replication but plays a critical role in IBDV pathogenesis. A deeper understanding of the biological functions of VP5 is lacking. This study utilized a prokaryotic system to express and purify soluble VP5 from the dominant epidemic strain of IBDV and developed a hybridoma cell line capable of secreting IBDV VP5 monoclonal antibody (MAb). The VP5 MAb demonstrated strong specificity for IBDV VP5 and could effectively discriminate between IBDV and its VP5-deleted strain. Furthermore, the antigen epitope of 137RRDLPKPE145 from IBDV VP5 was identified, which is the first detailed report of an IBDV VP5 antigen epitope. This antigen epitope, which is located at the C-terminus of VP5, is conserved across various IBDV serotype 1 strains. The findings of this study offer valuable insights for further exploration of gene function and differential detection of VP5.</div></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"308 ","pages":"Article 106254"},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of respiratory signal analysis to assess severity of Brachycephalic Obstructive Airway Syndrome (BOAS) in dogs","authors":"M. Dimopoulou ,&nbsp;H. Peterson ,&nbsp;O. Stensöta ,&nbsp;M. Karlsteen ,&nbsp;I. Ljungvall ,&nbsp;J. Rydén ,&nbsp;E. Skiöldebrand","doi":"10.1016/j.tvjl.2024.106261","DOIUrl":"10.1016/j.tvjl.2024.106261","url":null,"abstract":"<div><div>Brachycephalic Obstructive Airway Syndrome (BOAS) is a potentially life-threatening condition that can be challenging to diagnose and grade objectively. The aim of this study was to investigate the use of respiratory signal analysis to assess severity of BOAS in dogs. Hundred and seventeen client-owned dogs of brachycephalic and non-brachycephalic breeds were enrolled. Respiratory sounds were recorded using an electronic stethoscope before and after a 3-minute exercise test (ET). Dogs were assigned a BOAS severity grade (BOAS 0–3) using a validated respiratory functional grading scheme. Signal analysis techniques were used to identify seven sound variables. Analysis of variance (ANOVA) was used to investigate associations between variables and BOAS severity and receiver operating characteristic (ROC) curves to assess the diagnostic efficacy of each sound variable. For each sound variable, there was a significant association with BOAS grade. An increase in BOAS grade resulted in greater sound magnitude in the frequency spectrum (0–1000 Hz), and in a greater contribution of lower frequencies (170–260 Hz). The variable “Peak 1” had the best performance in predicting BOAS negative (BOAS 0 +1) versus BOAS positive dogs (BOAS 2 + 3) before the ET; area under the curve (AUC) = 76.6 % (95 % confidence interval 67.4–85.8 %), whereas the variable “Valley 1” had the highest predictive value after the ET; AUC = 87.8 % (95 % confidence interval 81.4–94.3 %). Respiratory signal analysis has good potential for assessing BOAS severity and could be valuable for clinicians in clinical decision processes and for breeders when selecting suitable breeding dogs.</div></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"308 ","pages":"Article 106261"},"PeriodicalIF":2.3,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic profile of prepartum dairy cows and its influence on the immediate postpartum period, colostrum quality and passive immunity transference","authors":"D.A.C. Hoffmann ,&nbsp;M. Furtado ,&nbsp;L.F. Bragança ,&nbsp;G. de M. Araujo ,&nbsp;F. Moreira ,&nbsp;V.R. Rabassa ,&nbsp;J.O. Feijó ,&nbsp;M.N. Corrêa ,&nbsp;V. Peripolli ,&nbsp;E. Schwegler","doi":"10.1016/j.tvjl.2024.106260","DOIUrl":"10.1016/j.tvjl.2024.106260","url":null,"abstract":"<div><div>The objective of this study was to evaluate which biochemical markers in the prepartum period of dairy cows influence the immediate postpartum period, the quality of colostrum, and the passive immunity transference in the calves. The experiment was performed on a commercial dairy farm with 52 pregnant multiparous Holstein cows. Animals that gave birth to twins or males were discarded from the experiment. On days −20 of the expected calving date and 24 hours after calving, blood collections, body condition score assessments, and animals weighing were performed. Blood samples from calves were performed 24 hours after colostrum intake. Calf plasma was used to estimate the passive immunity transfer by % brix and total plasma proteins (TPP). In the principal component analysis, it was shown that postpartum NEFA and BHBA was higher in cows with higher prepartum urinary pH and Ca lower prepartum. The cows with the highest NEFA and BHBA in pre and postpartum were the ones that had the lowest % brix in the colostrum. The % brix of the cow’s colostrum directly influenced the % brix and TPP of the calves. The NEFA in the cows prepartum negatively influenced the markers of immunity, the higher the NEFA, the lower the % brix of the cows’ colostrum, % brix of the calves, and TPP. In multivariate regression analyses it was shown that pre-calving NEFA was the marker that most influenced post-calving cow markers and calf % brix, along with colostrum time and % brix of the colostrum (P= 0.0092; r²= 0.83). Cows with higher values NEFA in the prepartum had lower calcemic in the immediate postpartum period. Prepartum NEFA was the marker that most influenced the cows’ immediate postpartum period, being directly related to Ca serum, and also to the passive immunity transference.</div></div>","PeriodicalId":23505,"journal":{"name":"Veterinary journal","volume":"308 ","pages":"Article 106260"},"PeriodicalIF":2.3,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142561083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}