Ultrasound in Obstetrics & Gynecology最新文献

{"title":"Application of artificial intelligence to ultrasound imaging for benign gynecological disorders: systematic review.","authors":"F Moro, M T Giudice, M Ciancia, D Zace, G Baldassari, M Vagni, H E Tran, G Scambia, A C Testa","doi":"10.1002/uog.29171","DOIUrl":"https://doi.org/10.1002/uog.29171","url":null,"abstract":"<p><strong>Objective: </strong>Although artificial intelligence (AI) is increasingly being applied to ultrasound imaging in gynecology, efforts to synthesize the available evidence have been inadequate. The aim of this systematic review was to summarize and evaluate the literature on the role of AI applied to ultrasound imaging in benign gynecological disorders.</p><p><strong>Methods: </strong>Web of Science, PubMed and Scopus databases were searched from inception until August 2024. Inclusion criteria were studies applying AI to ultrasound imaging in the diagnosis and management of benign gynecological disorders. Studies retrieved from the literature search were imported into Rayyan software and quality assessment was performed using the Quality Assessment Tool for Artificial Intelligence-Centered Diagnostic Test Accuracy Studies (QUADAS-AI).</p><p><strong>Results: </strong>Of the 59 studies included, 12 were on polycystic ovary syndrome (PCOS), 11 were on infertility and assisted reproductive technology, 11 were on benign ovarian pathology (i.e. ovarian cysts, ovarian torsion, premature ovarian failure), 10 were on endometrial or myometrial pathology, nine were on pelvic floor disorder and six were on endometriosis. China was the most highly represented country (22/59 (37.3%)). According to QUADAS-AI, most studies were at high risk of bias for the subject selection domain (because the sample size, source or scanner model was not specified, data were not derived from open-source datasets and/or imaging preprocessing was not performed) and the index test domain (AI models were not validated externally), and at low risk of bias for the reference standard domain (the reference standard classified the target condition correctly) and the workflow domain (the time between the index test and the reference standard was reasonable). Most studies (40/59) developed and internally validated AI classification models for distinguishing between normal and pathological cases (i.e. presence vs absence of PCOS, pelvic endometriosis, urinary incontinence, ovarian cyst or ovarian torsion), whereas 19/59 studies aimed to automatically segment or measure ovarian follicles, ovarian volume, endometrial thickness, uterine fibroids or pelvic floor structures.</p><p><strong>Conclusion: </strong>The published literature on AI applied to ultrasound in benign gynecological disorders is focused mainly on creating classification models to distinguish between normal and pathological cases, and on developing models to automatically segment or measure ovarian volume or follicles. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</p>","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional ultrasound demonstration of boomerang vessel of Type-III vasa previa at 21 weeks' gestation.","authors":"K Senthilvel, V Ravindran, K C Arivarasan, N Karthikeyan","doi":"10.1002/uog.29176","DOIUrl":"https://doi.org/10.1002/uog.29176","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiogenic factors alone or in combination with ultrasound Doppler criteria for risk classification among late-onset small fetuses with or without pre-eclampsia.","authors":"L Youssef, F Crispi, S Paolucci, J Miranda, S Lobmaier, F Crovetto, F Figueras, E Gratacos","doi":"10.1002/uog.29181","DOIUrl":"https://doi.org/10.1002/uog.29181","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the prognostic value of maternal angiogenic factors in late-onset small fetuses, alone or in combination with the ultrasound and Doppler parameters currently used for the classification of low-risk small-for-gestational-age (SGA) fetuses or high-risk fetal growth restriction (FGR), overall and according to the presence or absence of pre-eclampsia.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This was a prospective cohort study of women with a singleton pregnancy with a diagnosis of late-onset fetal smallness (defined as birth weight &lt; 10&lt;sup&gt;th&lt;/sup&gt; centile) and a gestational age of ≥ 34 weeks at delivery. Ultrasound assessment of estimated fetal weight (EFW) and Doppler assessment of uterine artery pulsatility index (UtA-PI) and cerebroplacental ratio (CPR) were performed every 1-2 weeks. Biochemical analysis of the angiogenic factors placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) in maternal peripheral venous blood samples was performed using enzyme-linked immunosorbent assay within 1-2 weeks after diagnosis of SGA or FGR. The primary outcome was adverse perinatal outcome, defined as a composite of emergency Cesarean section for non-reassuring fetal status, metabolic acidosis (umbilical artery pH &lt; 7.0), neonatal unit admission and/or perinatal death. The predictive value of EFW &lt; 3&lt;sup&gt;rd&lt;/sup&gt; centile, Doppler parameters (UtA-PI &gt; 95&lt;sup&gt;th&lt;/sup&gt; centile and CPR &lt; 5&lt;sup&gt;th&lt;/sup&gt; centile) and sFlt-1/PlGF ratio &gt; 95&lt;sup&gt;th&lt;/sup&gt; centile, alone or in combination, was assessed using logistic regression analysis in the overall population and stratified by presence or absence of pre-eclampsia developing at any time before delivery.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Among the 602 included cases, 91 (15.1%) developed pre-eclampsia and 511 (84.9%) did not. In the overall study population, all parameters were associated independently with adverse perinatal outcome: EFW &lt; 3&lt;sup&gt;rd&lt;/sup&gt; centile (adjusted odds ratio (aOR), 2.58 (95% CI, 1.67-4.00)), UtA-PI &gt; 95&lt;sup&gt;th&lt;/sup&gt; centile (aOR, 1.92 (95% CI, 1.25-2.94)), CPR &lt; 5&lt;sup&gt;th&lt;/sup&gt; centile (aOR, 2.35 (95% CI, 1.46-3.78)) and sFlt-1/PlGF ratio &gt; 95&lt;sup&gt;th&lt;/sup&gt; centile (aOR, 1.71 (95% CI, 1.09-2.69)). Only sFlt-1/PlGF ratio &gt; 95&lt;sup&gt;th&lt;/sup&gt; centile was associated independently with adverse perinatal outcome in cases with pre-eclampsia, whereas in those without pre-eclampsia, only EFW &lt; 3&lt;sup&gt;rd&lt;/sup&gt; centile and CPR &lt; 5&lt;sup&gt;th&lt;/sup&gt; centile were associated independently with adverse perinatal outcome. In the overall population, the detection rate (DR) and false-positive rate for adverse perinatal outcome were, respectively: 39.8% (95% CI, 31.7-47.9%) and 16.9% (95% CI, 10.7-23.1%) for sFlt-1/PlGF ratio &gt; 95&lt;sup&gt;th&lt;/sup&gt; centile alone; 86.8% (95% CI, 83.4-90.2%) and 61.9% (95% CI, 57.1-66.7%) for a combined model of EFW &lt; 3&lt;sup&gt;rd&lt;/sup&gt; centile, UtA-PI &gt; 95&lt;sup&gt;th&lt;/sup&gt; centile and CPR &lt; 5&lt;sup&gt;th&lt;/sup&gt; centile; 81.3% (95% CI, 77.3-85.3%) a","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High success rate in demonstration of soft palate in early and late mid-trimester ultrasound scans.","authors":"D A Lasry, D V Valsky, N Cohen, A Nahum, S M Cohen, S Yagel","doi":"10.1002/uog.29164","DOIUrl":"https://doi.org/10.1002/uog.29164","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mixed germ cell tumor presenting with mixed sonographic appearance and unique clinical presentation.","authors":"S Dumont, F Amant, W Froyman, D Timmerman, A-S Van Rompuy, T Van den Bosch","doi":"10.1002/uog.29179","DOIUrl":"https://doi.org/10.1002/uog.29179","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143041677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and acceptability of randomized controlled trial of intervention vs expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy.","authors":"A Khalil, S Prasad, J J Kirkham, R Jackson, K Woolfall","doi":"10.1002/uog.29175","DOIUrl":"https://doi.org/10.1002/uog.29175","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143041632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Could maternal rest improve adverse outcome in fetuses defined by abnormal growth trajectory?","authors":"G R DeVore","doi":"10.1002/uog.29152","DOIUrl":"https://doi.org/10.1002/uog.29152","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra- and interobserver agreement of proposed objective transvaginal ultrasound image-quality scoring system for use in artificial intelligence algorithm development.","authors":"A Deslandes, J C Avery, H-T Chen, M Leonardi, S Knox, G Lo, R O'Hara, G Condous, M L Hull","doi":"10.1002/uog.29178","DOIUrl":"https://doi.org/10.1002/uog.29178","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;The development of valuable artificial intelligence (AI) tools to assist with ultrasound diagnosis depends on algorithms developed using high-quality data. This study aimed to test the intra- and interobserver agreement of a proposed image-quality scoring system to quantify the quality of gynecological transvaginal ultrasound (TVS) images, which could be used in clinical practice and AI tool development.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A proposed scoring system to quantify TVS image quality was created following a review of the literature. This system involved a score of 1-4 (2 = poor, 3 = suboptimal and 4 = optimal image quality) assigned by a rater for individual ultrasound images. If the image was deemed inaccurate, it was assigned a score of 1, corresponding to 'reject'. Six professionals, including two radiologists, two sonographers and two sonologists, reviewed 150 images (50 images of the uterus and 100 images of the ovaries) obtained from 50 women, assigning each image a score of 1-4. The review of all images was repeated a second time by each rater after a period of at least 1 week. Mean scores were calculated for each rater. Overall interobserver agreement was assessed using intraclass correlation coefficient (ICC), and interobserver agreement between paired professionals and intraobserver agreement for all professionals were assessed using weighted Cohen's kappa and ICC.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Poor levels of interobserver agreement were obtained between the six raters for all 150 images (ICC, 0.480 (95% CI, 0.363-0.586)), as well as for assessment of the uterine images only (ICC, 0.359 (95% CI, 0.204-0.523)). Moderate agreement was achieved for the ovarian images (ICC, 0.531 (95% CI, 0.417-0.636)). Agreement between the paired sonographers and sonologists was poor for all images (ICC, 0.336 (95% CI, -0.078 to 0.619) and 0.425 (95% CI, 0.014-0.665), respectively), as well as when images were grouped into uterine images (ICC, 0.253 (95% CI, -0.097 to 0.577) and 0.299 (95% CI, -0.094 to 0.606), respectively) and ovarian images (ICC, 0.400 (95% CI, -0.043 to 0.669) and 0.469 (95% CI, 0.088-0.689), respectively). Agreement between the paired radiologists was moderate for all images (ICC, 0.600 (95% CI, 0.487-0.693)) and for their assessment of uterine images (ICC, 0.538 (95% CI, 0.311-0.707)) and ovarian images (ICC, 0.621 (95% CI, 0.483-0.728)). Weak-to-moderate intraobserver agreement was seen for each of the raters with weighted Cohen's kappa ranging from 0.533 to 0.718 for all images and from 0.467 to 0.751 for ovarian images. Similarly, for all raters, the ICC indicated moderate-to-good intraobserver agreement for all images overall (ICC ranged from 0.636 to 0.825) and for ovarian images (ICC ranged from 0.596 to 0.862). Slightly better intraobserver agreement was seen for uterine images, with weighted Cohen's kappa ranging from 0.568 to 0.808 indicating weak-to-strong agreement, and ICC ranging","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply.","authors":"M L Larsen, S Kumar","doi":"10.1002/uog.29157","DOIUrl":"https://doi.org/10.1002/uog.29157","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrahepatic portosystemic shunt: salvage mechanism for oligohydramnios complicating fetal growth restriction.","authors":"Y Gilboa, L Drukker, J Bar, D Berbing-Goldstein, Y Geron, Y Mozer Glassberg, E Hadar, R Charach, R Bardin","doi":"10.1002/uog.29163","DOIUrl":"https://doi.org/10.1002/uog.29163","url":null,"abstract":"<p><strong>Objective: </strong>Portosystemic shunts in growth-restricted fetuses are more common than previously thought. We aimed to describe fetuses with growth restriction and transient oligohydramnios in which a congenital intrahepatic portosystemic shunt (CIPSS) was noted during follow-up.</p><p><strong>Methods: </strong>This was a retrospective study of all fetuses diagnosed with growth restriction and transient oligohydramnios during a 5-year period in a large tertiary referral center. Our routine evaluation of growth-restricted fetuses includes monitoring of estimated fetal weight, assessment of biophysical profile, Doppler imaging, thorough examination of the umbilical-portal system and evaluation of cardiac function using fetal tricuspid annular plane systolic excursion (f-TAPSE). We compared these parameters before and after the resolution of the oligohydramnios using descriptive statistics and the Wilcoxon signed-rank test for paired non-parametric variables. During the surveillance of fetuses with transient oligohydramnios, we noted the appearance of a CIPSS and followed up such cases after birth.</p><p><strong>Results: </strong>A total of 2144 women with a singleton pregnancy with suspected fetal growth restriction were referred to our center between January 2018 and December 2022. In 12 fetuses, oligohydramnios was evident upon initial assessment, and a CIPSS was diagnosed with normalization of amniotic fluid level. The median gestational age at diagnosis of growth restriction and oligohydramnios was 25 (range, 21-30) weeks. The estimated fetal weight was at the 1^st percentile in 10/12 fetuses. The median amniotic fluid index was 5 (range, 2-5) cm at the initial appointment and improved significantly to 13 (range, 11-20) cm following the shunt diagnosis (P = 0.002). Among fetuses with f-TAPSE data available, the f-TAPSE increased significantly from 4.0 (range, 3.0-5.0) mm before the diagnosis of CIPSS to 8.0 (range, 5.0-9.4) mm following the diagnosis (P = 0.043). The median gestational age at delivery was 36.3 (range, 30.8-38.4) weeks. In nine (75%) fetuses, the diagnosed shunt was left portal to left hepatic vein. Neonatal follow-up revealed spontaneous shunt resolution within 30 months in all newborns. One newborn required embolization owing to suspected shunt, however, no shunt was detected during the procedure.</p><p><strong>Conclusions: </strong>The development of CIPSS in growth-restricted fetuses with oligohydramnios appears to improve hemodynamic status as evidenced by normalization of amniotic fluid index and increase in f-TAPSE. Evaluation of the liver portal system in fetuses with growth restriction offers an understanding of the shunt salvage phenomenon. © 2025 International Society of Ultrasound in Obstetrics and Gynecology.</p>","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}