Twin Research and Human Genetics最新文献_第5页

Common Genetic Influence on the Relationship Between Gaming Addiction and Attention Deficit Hyperactivity Disorder in Young Adults: A Twin Study. 青少年游戏成瘾与注意力缺陷多动障碍之间的共同遗传影响：一项双胞胎研究。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-10-28 DOI: 10.1017/thg.2024.29

Seol-Ah Lee, Yoon-Mi Hur

{"title":"Common Genetic Influence on the Relationship Between Gaming Addiction and Attention Deficit Hyperactivity Disorder in Young Adults: A Twin Study.","authors":"Seol-Ah Lee, Yoon-Mi Hur","doi":"10.1017/thg.2024.29","DOIUrl":"10.1017/thg.2024.29","url":null,"abstract":"Although the relationship between gaming addiction (GA) and attention deficit hyperactivity disorder (ADHD) is well established, the causal mechanism of this relationship remains ambiguous. We aimed to investigate whether common genetic and/or environmental factors explain the GA-ADHD relationship. We recruited 1413 South Korean adult twins (837 monozygotic [MZ], 326 same-sex dizygotic [DZ], and 250 opposite-sex DZ twins; mean age = 23.1 ± 2.8 years) who completed an online survey on GA and related traits. Correlational analysis and bivariate model-fitting analysis were conducted. Phenotypic correlation between GA and ADHD in the present sample was 0.55 (95% CI [0.51, 0.59]). Bivariate model-fitting analysis revealed that genetic variances were 69% (95% CI [64%, 73%]) and 68% (95% CI [63%, 72%]) for ADHD and GA respectively. The remaining variances (ADHD: 31%; GA: 32%) were associated with nonshared environmental variances, including measurement error. Genetic and nonshared environmental correlations between ADHD and GA were 0.68 (95% CI [0.62, 0.74]) and 0.22 (95% CI [0.13, 0.30]) respectively, which indicates that shared genes can explain 82% of the phenotypic correlation between ADHD and GA. Our study demonstrated that the ADHD-GA association was largely due to shared genetic vulnerability.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"198-203"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Sibling Patterns in the Educational Attainment of Hungarian Twins. 兄弟姐妹模式在匈牙利双胞胎教育成就中的作用。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-11-11 DOI: 10.1017/thg.2024.37

András Pári, Ágnes Engler

{"title":"The Role of Sibling Patterns in the Educational Attainment of Hungarian Twins.","authors":"András Pári, Ágnes Engler","doi":"10.1017/thg.2024.37","DOIUrl":"10.1017/thg.2024.37","url":null,"abstract":"Studies concerning twins with a sociological focus are scarce in Hungary as well as international research, although the number of twin births has increased dramatically worldwide. The raising and education of twins are tasks demanding special attention from both the family and institutions. In our study we examine these aspects, looking back from adulthood, using the narrow scope of the available data from research based on the 'Hungarostudy 2021' database (N total: 7000; n twins: 106). Our results, corresponding to the hypotheses of educational sociology, demonstrate how the relationships between family size and school career and increasing number of siblings reduces the chances of high educational attainment. A regression analysis confirmed that both the number of siblings and a later position in the birth order reduces the chance of obtaining a higher education. For the second child in a family, the chance of earning a university degree is reduced to to 0.743. The role of a large family concerning higher education showed a stronger relationship in the case of twins compared to nontwins. For twins, the sibling pattern has a decisive effect in educational attainment. Twins themselves have a 1.449 times higher chance of obtaining a higher education compared to nontwins (p = 0.101), and fraternal twins have half (0.517) the chance of obtaining a higher education compared to identical twins; but both results are not significant (p = 0.156).","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"231-240"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THG volume 27 issue 4-5 Cover. THG 第 27 卷第 4-5 期封面。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-12-20 DOI: 10.1017/thg.2024.45

引用次数: 0

Review of The Twin Children of the Holocaust: Stolen Childhood and the Will to Survive, by Nancy L. Segal - CORRIGENDUM. 回顾大屠杀的双胞胎孩子:被偷走的童年和生存的意志，南希·l·西格尔著-勘误表。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2023-12-01 DOI: 10.1017/thg.2023.47

Jeffrey M Craig

引用次数: 0

Tribute to Dr Milton Diamond: Twin Studies of Transsexuality/Twin Research Reviews: Loss of a Twin Brother (Recent Memoir); Oxytocin Adminstration During Twin Delivery; Models of Monochorionic Twinning; Twins' Brain Responses to Watching Films/Human Interest: Oldest Conjoined Twins Pass Away; Twins Discordant for Child Abuse; Twins Married to Twins; Rare Quadruplet Set Delivered; Questions of Coincidence; Reared-Apart Twin Valedictorians. 向米尔顿·戴蒙德博士致敬：变性的双胞胎研究/双胞胎研究评论：失去一个双胞胎兄弟（最近的回忆录）；双胎分娩时催产素的应用单绒毛膜孪生模型；双胞胎对观看电影/人类兴趣的大脑反应：最年长的连体双胞胎去世；虐待儿童的双胞胎不一致；双胞胎嫁给双胞胎；罕见四胞胎套装交付；巧合问题；分开的双胞胎毕业生代表。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-12-20 DOI: 10.1017/thg.2024.34

Nancy L Segal

{"title":"Tribute to Dr Milton Diamond: Twin Studies of Transsexuality/Twin Research Reviews: Loss of a Twin Brother (Recent Memoir); Oxytocin Adminstration During Twin Delivery; Models of Monochorionic Twinning; Twins' Brain Responses to Watching Films/Human Interest: Oldest Conjoined Twins Pass Away; Twins Discordant for Child Abuse; Twins Married to Twins; Rare Quadruplet Set Delivered; Questions of Coincidence; Reared-Apart Twin Valedictorians.","authors":"Nancy L Segal","doi":"10.1017/thg.2024.34","DOIUrl":"10.1017/thg.2024.34","url":null,"abstract":"A tribute to the life and career of Dr Milton Diamond, a leading figure in twin studies of transsexuality and gender identity, is presented. Dr Diamond is famous for revealing the truth about the unsuccessful effort to change a monozygotic male Canadian twin into a female, following accidental ablation of his penis during circumcision. A short summary of recent twin research on human sexuality and transsexuality, focused on Dr Diamond's contributions, is then presented. The tribute and overview are followed by research reviews involving the loss of a twin brother; oxytocin adminstration during twin delivery; models of monochorionic twinning; and twins' brain responses to watching films. The final section of this article covers topics of human interest, including the passing of the world's oldest conjoined twins; twins discordant for child abuse; twins married to twins; the delivery of a rare quadruplet set; questions of coincidence; and reared-apart twin valedictorians.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":"27 4-5","pages":"256-260"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Placental Vascular Anastamoses and Associated Pathologies in Dichorionic Twin Gestations. 二绒毛膜双胎妊娠的胎盘血管吻合及相关病理。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-11-07 DOI: 10.1017/thg.2024.35

Eesha Dave, Mert Ozan Bahtiyar, William Campbell, Raffaella Morotti, Katherine Kohari

引用次数: 0

Twin Data Support a Sensitive Period for Singing Ability. 双胞胎数据支持歌唱能力的敏感期

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-10-02 DOI: 10.1017/thg.2024.30

Daniel Yeom, Nick Haslam, Yi Ting Tan, Gary E McPherson, Sarah J Wilson

{"title":"Twin Data Support a Sensitive Period for Singing Ability.","authors":"Daniel Yeom, Nick Haslam, Yi Ting Tan, Gary E McPherson, Sarah J Wilson","doi":"10.1017/thg.2024.30","DOIUrl":"10.1017/thg.2024.30","url":null,"abstract":"As with many other musical traits, the social environment is a key influence on the development of singing ability. While the familial singing environment is likely to be formative, its role relative to other environmental influences such as training is unclear. We used structural equation modeling to test relationships among demographic characteristics, familial environmental variables (early and current singing with family), vocal training, and singing ability in a large, previously documented sample of Australian twins (N = 1163). Notably, early singing with family, and to a lesser extent vocal training, predicted singing ability, whereas current singing with family did not. Early familial singing also mediated the relationship between sex and singing ability, with men who sang less with family during childhood showing poorer ability. Bivariate twin models between early familial singing and singing ability showed the phenotypic correlation was largely explained by shared environmental influences. This raises the possibility of a sensitive period for singing ability, with sociocultural expectations around singing potentially differentiating the developmental trajectories of this skill for men and women.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"204-214"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breastfeeding Practices in the Twin Town of India - A Cross-Sectional Study. 印度双城镇的母乳喂养实践--一项横断面研究。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-10-02 DOI: 10.1017/thg.2024.31

Geeta Bhardwaj, Moonjelly V Smitha

{"title":"Breastfeeding Practices in the Twin Town of India - A Cross-Sectional Study.","authors":"Geeta Bhardwaj, Moonjelly V Smitha","doi":"10.1017/thg.2024.31","DOIUrl":"10.1017/thg.2024.31","url":null,"abstract":"The global rise in twinning rates poses health challenges due to increased risks for infants and mothers. Despite the benefits, breastfeeding rates among multiples are low, with exclusive breastfeeding (EBF) particularly scarce compared to singletons. Our study focuses on the mothers of twins in a unique population in Kodinhi village, Kerala, India, known for its high twinning rates, which aims to contribute to existing knowledge of breastfeeding practices and perspectives in a high twinning environment and offer valuable insights to promote optimal breastfeeding among mothers of twins. A retrospective cross-sectional survey was adopted. Seventy-five mothers with twins under 3 years of age from Kodinhi and neighboring areas were interviewed face to face using structured validated tools. Data collection focused on quantitative data supplemented by narrative descriptions. Most women delivered preterm (57.3%), operative delivery (58.7%), and had a late initiation of breastfeeding (32.9% within 24 hours). Colostrum feed was common (86.7%). The EBF rate was 4%, with 47.9% initiating nonexclusive breastfeeding before 3 months, and most of the twins (46.6%) were breastfed for 1-2 years. Fatigue (69.9%) and low milk supply (38.7%) were chief concerns. While 16.4% of mothers opted for a tandem breastfeeding technique, many preferred consecutive feeding as tandem was challenging. Mothers in Kodinhi demonstrated commendable efforts in breastfeeding twins; despite the low rate of EBF, breastfeeding extended to 1-2 years. Evidence-based interventions and personalized support, primarily focusing on maternal perspectives of milk insufficiency, fatigue and breastfeeding techniques, are crucial for sustaining optimal breastfeeding practices among mothers of twins.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"241-250"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Link Between Parental Sociodemographic Characteristics and Multiple Births: Insights from National Birth Data in Japan, 1995-2020. 探索父母的社会人口特征与多胞胎之间的联系：1995-2020 年日本全国出生数据的启示》。

IF 1 4区医学

Twin Research and Human Genetics Pub Date : 2024-08-01 Epub Date: 2024-10-03 DOI: 10.1017/thg.2024.36

Tasuku Okui, Naoki Nakashima

{"title":"Exploring the Link Between Parental Sociodemographic Characteristics and Multiple Births: Insights from National Birth Data in Japan, 1995-2020.","authors":"Tasuku Okui, Naoki Nakashima","doi":"10.1017/thg.2024.36","DOIUrl":"10.1017/thg.2024.36","url":null,"abstract":"This present study investigated the parental characteristics of multiple births using national birth data in Japan. This study included birth data from Vital Statistics: Occupational and Industrial Aspects every five fiscal years from 1995 to 2020. The multiple birth rates were defined as the number of live-birth deliveries with multiple fetuses (e.g., twins, triplets) per total live-birth deliveries. Parental ages, nationalities, occupations and household occupation (occupation of the top earner of the household) were considered as parental characteristics. The multiple birth rates were calculated based on parental characteristics for each year, and a log-binomial regression model was used to assess the association between parental characteristics and multiple births. The multiple birth rate for Japanese mothers consistently exceeded that for non-Japanese mothers over the years, and the rate increased progressively from manual workers to lower non-manual workers and then to upper non-manual workers for both maternal and paternal occupations. The regression results indicated that the risk ratio (RR) for multiple births among non-Japanese mothers was significantly lower than that among Japanese mothers. Moreover, concerning household occupation, the RRs of self-employed individuals, full-time employees at smaller companies, others, and the unemployed were significantly lower than those of full-time employees at larger companies. Furthermore, the RRs of lower non-manual and manual workers were significantly lower than those of upper non-manual workers in maternal and paternal occupations. The results suggested an association between multiple births and parental socioeconomic status in Japan.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"223-230"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Rheumatoid Arthritis and Clonal Hematopoiesis: A Mendelian Randomization Study. 类风湿性关节炎与克隆性造血之间的关系：孟德尔随机研究

IF 0.9 4区医学

Twin Research and Human Genetics Pub Date : 2024-06-03 DOI: 10.1017/thg.2024.24

Jie Zhang, Chun Zhou, Shaoxing Guan

{"title":"Association Between Rheumatoid Arthritis and Clonal Hematopoiesis: A Mendelian Randomization Study.","authors":"Jie Zhang, Chun Zhou, Shaoxing Guan","doi":"10.1017/thg.2024.24","DOIUrl":"https://doi.org/10.1017/thg.2024.24","url":null,"abstract":"Immunity activation and inflammation are the main characteristics of rheumatoid arthritis and clonal hematopoiesis. However, it remains unclear whether rheumatoid arthritis increase the risk of clonal hematopoiesis. Here, a Mendelian randomization (MR) analysis was conduct to explore the causal effects of rheumatoid arthritis on clonal hematopoiesis. Summary statistics data of rheumatoid arthritis (13,838 cases and 33,742 controls) and clonal hematopoiesis (10,203 cases and 173,918 controls) derived from a genomewide association study were selected to analyze. We selected inverse-variance weighted, MR-Egger, weighted median, simple mode, and weighted mode to evaluate the causal effect of rheumatoid arthritis on clonal hematopoiesis. The two-sample MR analysis suggested a strong causal relationship between rheumatoid arthritis and clonal hematopoiesis by inverse-variance weighted (OR = 1.002311673, 95% CI [1.000110757, 1.004517433], p = .039706) and weighted median (OR = 1.002311673, 95% CI [1.000110757, 1.004517433], p = .039518447) methods. No significant pleiotropy or heterogeneity was found in the sensitivity analysis. These results supported a potentially causal relationship between rheumatoid arthritis and clonal hematopoiesis, and the exposure of rheumatoid arthritis increased the risks of clonal hematopoiesis. Our findings highlight the importance of how chronic inflammation and immune activation induced rheumatoid arthritis enhances the risks of clonal hematopoiesis, and that early intervention with rheumatoid arthritis patients might reduce the clonal hematopoiesis risks in rheumatoid arthritis patients. Moreover, our study provides clues for prediction of risk factors and potential mechanisms of clonal hematopoiesis.","PeriodicalId":23446,"journal":{"name":"Twin Research and Human Genetics","volume":" ","pages":"1-5"},"PeriodicalIF":0.9,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0