Urologia Internationalis最新文献

{"title":"Ureteroplasty for the Repair of Ureteral Stricture Using Lingual Mucosa and Buccal Mucosa Grafts: A Meta-Analysis.","authors":"Xin Zeng, Lingyu Xie, Zhicheng Zeng, Yuanhu Yuan, Hui Xu","doi":"10.1159/000545041","DOIUrl":"10.1159/000545041","url":null,"abstract":"<p><strong>Introduction: </strong>The study aims to analyze the outcomes of buccal mucosa and lingual mucosa graft reconstruction for repairing ureteral strictures, assessing the efficacy and safety of both surgical approaches.</p><p><strong>Methods: </strong>A computer search was conducted on PubMed, Embase, and Web of Science using keywords such as \"buccal mucosa,\" \"lingual mucosa,\" \"oral mucosa,\" \"ureteral stenosis,\" and \"ureteral reconstruction\" to gather relevant literature on lingual mucosa and the efficacy of buccal mucosal reconstruction for ureteral repair. The search spanned from January 2000 to March 2024, focusing on experiments that assessed lingual mucosa graft ureteroplasty (LMGU) or buccal mucosa graft ureteroplasty (BMGU). Variables examined included reconstruction success rate, intraoperative blood loss, stricture length, and perioperative complications. Sensitivity analysis was employed to assess result stability, while funnel plots were utilized to evaluate publication bias in the literature.</p><p><strong>Results: </strong>A total of 16 single-arm studies were included in the analysis. The combined reconstruction success rates for the LMGU group and BMGU group were 99% (95% CI: 95%-100%) and 95% (95% CI: 91%-98%), respectively. The mean operation time for the LMGU group was 208.62 min (95% CI: 181.56-235.68) and for the BMGU group was 190.65 min (95% CI: 164.38-216.93). Intraoperative blood loss volumes for the LMGU group and BMGU group were 62.33 mL (95% CI: 43.15-81.51) and 113.44 mL (95% CI: 77.64-146.23), respectively. Stenosis lengths in the LMGU group and BMGU group were 3.98 cm (95% CI: 3.27-4.69) and 4.12 cm (95% CI: 3.24-5) respectively, with a maximum stenosis length repaired of 8 cm in both groups. The incidence of postoperative complications was 25% (95% CI: 15%-36%) in the BMGU group and 18% (95% CI: 11%-26%) in the LMGU group.</p><p><strong>Conclusion: </strong>LMGU and BMGU are both effective and safe surgical methods for the treatment of long-segment ureteral stenosis. They have shown high effectiveness in treating mid- and upper-segment ureteral stenosis ≤8 cm.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-13"},"PeriodicalIF":1.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Separated Transfixing Uretero-Enteral Anastomosis Method in Robot-Assisted Radical Cystectomy with Ileal Conduit: Early Induction Experience.","authors":"Yasukazu Nakanishi, Ryo Andy Ogasawara, Naoki Imasato, Minoru Inoue, Kohei Hirose, Ken Sekiya, Madoka Kataoka, Shugo Yajima, Hitoshi Masuda","doi":"10.1159/000545124","DOIUrl":"10.1159/000545124","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to evaluate the initial outcomes of a novel transfixing uretero-enteral anastomosis technique in robot-assisted radical cystectomy (RARC) with ileal conduit in an intracorporeal urinary diversion (ICUD), focusing on its potential to reducing the incidence of uretero-enteric anastomotic stricture.</p><p><strong>Methods: </strong>The study subjects were 11 patients who underwent RARC and ileal conduit created as an ICUD at a single cancer center between 2022 and 2024. The technique involved opening the ventral side of the oral end of the separated ileum approximately 5 cm apart. Two small holes were made 2 cm from the oral end on the dorsal side, through which the ureter passed to the luminal side. The distal end of the ureter was spatulated, and four knotted sutures were placed at the base using 4-0 absorbable sutures. The distal end of the ureter was anchored using two knotted sutures, and the liberated portion was closed using 3-0 absorbable suture in a running fashion.</p><p><strong>Results: </strong>The median total operation time was 418 min (range: 269-467 min), with a median console time of 93 min (range: 80-129 min) for urinary diversion. Two patients required temporary stent reinsertion because of hydronephrosis; however, no pyelonephritis occurred. Two patients (18.2%) had complications of Clavien-Dindo classification 3 or higher, both of which only required temporary stent reinsertion. Postoperative renal function was preserved in all the patients.</p><p><strong>Conclusions: </strong>In our initial experience, the transfixing uretero-enteral anastomosis technique was successful in stabilizing anastomoses in ICUD.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of 10-20 mm Renal Stones: Shock Wave Lithotripsy versus Flexible Ureteroscopy.","authors":"Erhan Erdoğan, Ahmet Fatih Kanberoğlu, Alper Aşık, Göksu Sarıca, Kemal Sarıca","doi":"10.1159/000545108","DOIUrl":"10.1159/000545108","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to compare the efficacy and safety of shock wave lithotripsy (SWL) and flexible ureteroscopy (fURS) in treating unilateral moderate-sized (10-20 mm) kidney stones, with a focus on changes in quality of life (QoL).</p><p><strong>Methods: </strong>This study included 112 patients with unilateral radiopaque kidney stones. Patients were divided into two groups: SWL (n = 64) and fURS (n = 48). Treatment outcomes, including QoL changes, were evaluated comparatively between the groups.</p><p><strong>Results: </strong>Both groups were similar in terms of age, gender, stone size, and density. Short-term (4-week) stone-free rates (SFRs) were higher in the fURS group (79.17% vs. 51.56%, p = 0.003). However, at 3 months, there was no significant difference in SFRs (89.8% vs. 85.2%, p = 0.098). Pain levels, assessed using the Visual Analog Scale, showed no difference 1-h post-procedure (p = 0.338), but SWL had lower pain scores at 4 h (p = 0.002). QoL, assessed with the SF-36 questionnaire, indicated an advantage for SWL in energy/fatigue parameters (p = 0.017), with no significant differences in other domains. SWL was particularly beneficial for energy levels and emotional well-being.</p><p><strong>Conclusions: </strong>SWL's noninvasive nature, reduced pain levels, and advantages in specific QoL parameters make it an effective treatment option for medium-sized kidney stones. While fURS offers better short-term stone clearance, SWL demonstrates comparable long-term efficacy with added QoL benefits.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Procalcitonin, Systemic Inflammatory Index, and C-Reactive Protein and Skin Reconstruction in Fournier's Gangrene Patients: A Retrospective Single-Center Study.","authors":"Salih Bürlukkara, Özer Baran","doi":"10.1159/000545013","DOIUrl":"10.1159/000545013","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to examine the relationship between skin reconstruction and systemic inflammatory index (SII), procalcitonin in Fournier's gangrene.</p><p><strong>Methods: </strong>Forty-seven male patients who underwent debridement and were diagnosed with Fournier's gangrene were included in this retrospective study. The patient groups were divided into two groups. Group 1 included 26 patients who required primary skin closure, and Group 2 included 21 patients who required skin grafts and flaps. Data regarding initial symptoms, physical examination findings, vital signs, and laboratory tests were collected through archive scanning. Patients with available data for the Fournier's gangrene severity index (FGSI), Uludağ's Fournier's gangrene severity index (UFGSI), procalcitonin, C-reactive protein (CRP), and SII calculations were included in the study.</p><p><strong>Results: </strong>A significant difference in vital signs was found between the groups. Fever, pulse and respiratory rate were significantly greater in Group 2 than in Group 1 (p = 0.747). There was no significant difference in body mass index (BMI) or duration of hospitalization (p = 0.983). The average procalcitonin level of the patients measured preoperatively was 1.01 in Group 1 and 2.30 in Group 2. In Group 1, the average CRP level was 111.90, the SII was 3,460.00; in Group 2, the CRP level was 165.00, the SII was 6,544.00, and this difference between the two groups was significant (p = 0.011-0.018).</p><p><strong>Conclusion: </strong>CRP, procalcitonin, and SII rates can be measured simply, easily applied, and can provide insight into predicting skin reconstruction.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Radical Cystectomy with Orthotopic Neobladder Reconstruction in Patients Developing Bladder Cancer after Prior Radical Prostatectomy, Radiation Therapy, or BPH Surgery.","authors":"Nikolaos Pyrgidis, Yannic Volz, Sarah Takayama Fouladgar, Benedikt Ebner, Philipp Weinhold, Julian Marcon, Michael Chaloupka, Christian G Stief, Gerald Bastian Schulz, Patrick Keller","doi":"10.1159/000545103","DOIUrl":"10.1159/000545103","url":null,"abstract":"<p><strong>Introduction: </strong>Current evidence suggests that prior prostatic interventions, such as prostatectomy, radiation, or transurethral surgery, may increase the risk of incontinence in patients undergoing radical cystectomy (RC) with ileal orthotopic neobladder reconstruction. We aimed to evaluate the short- and long-term complications, functional outcomes of neobladder reconstruction in patients undergoing RC after prior prostatic procedures.</p><p><strong>Methods: </strong>We analyzed patients who underwent RC after prior prostatic intervention in our department from 2013 to 2022. A comparison was made between patients receiving neobladder reconstruction (ONB) versus ileal conduit, including propensity score matching for age and preoperative continence.</p><p><strong>Results: </strong>We included 79 patients who underwent RC for bladder cancer after prior prostatic intervention. Of them, 43 (54%) patients had previously undergone BPH surgery, 29 (37%) radical prostatectomy, and 7 (9%) prostate radiation therapy. An ileal conduit was performed in 62 (78%) cases. Patients presented similar baseline characteristics, perioperative complications, and quality of life after RC. Accordingly, after propensity-score-matching patients with ONB after prior prostatic intervention and patients who received ONB without prior prostatic intervention did not differ significantly in their baseline characteristics, perioperative complications, and quality of life. Overall, 24% of patients without prior intervention reported incontinence, compared to 53% with prior prostatic intervention.</p><p><strong>Conclusion: </strong>Neobladder reconstruction remains to be a feasible option in patients undergoing RC after prior prostatic intervention.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SIRT7 Expression Predicts Poor Prognosis in Upper Tract Urothelial Carcinoma Undergoing Postoperative Platinum-Based Adjuvant Chemotherapy.","authors":"Yudong Cao, Jinchao Ma, Shuo Wang, Xiao Yang, Mengping Long, Yongpeng Ji, Ziyi Yu, Ruijian You, Chen Lin, Yong Yang, Peng Du","doi":"10.1159/000544698","DOIUrl":"10.1159/000544698","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to evaluate the expression of SIRT7 in upper tract urothelial carcinoma (UTUC) as well as the predictive value for prognosis in patients undergoing radical nephroureterectomy followed platinum-based adjuvant chemotherapy.</p><p><strong>Methods: </strong>Pathological samples of 146 UTUC with clinical stage T2 and above undergoing radical nephrectomy (RNU) were collected. All patients received adjuvant cisplatin-based chemotherapy and 40 UTUC patients received second-line immunotherapy after disease progression. The relationship between the expression level of SIRT7 by immunohistochemistry and clinicopathological characteristics, disease-free survival (DFS), overall survival (OS), and OS after progression (POS) was analyzed.</p><p><strong>Results: </strong>Over a mean follow-up 47 months, 61 (41.8%) patients experienced recurrence and 42 (28.8%) patients died due to UTUC. The results revealed that 70.2% of UTUC tissue samples exhibited high expression levels of SIRT7. High expression of SIRT7 is associated with lymph node metastasis (p < 0.001), lymphovascular invasion (p = 0.001), and histological differentiation (p = 0.025). In addition, UTUC patients with elevated SIRT7 expression experienced significantly shorter DFS (hazard ratio [HR] 3.760, 95% CI: 1.884-7.504, p < 0.001 and OS (HR 2.706, 95% CI: 1.235-5.929, p = 0.013). Multivariate analyses demonstrated that SIRT7 served as a significant predictor for DFS (HR 2.337, 95% CI: 1.117-4.890, p = 0.024) in UTUC patients. Furthermore, we found SIRT7 high expression is associated with prolonged POS in patients progressed after adjuvant cisplatin-based chemotherapy and received second-line immunotherapy.</p><p><strong>Conclusion: </strong>SIRT7 is an independent prognostic marker of poor DFS in locally advanced UTUC patients after RNU. Moreover, these data suggest that SIRT7 could potentially serve as a target for assessing the efficacy of chemotherapy and immunotherapy in UTUC.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stage Migration in Urological Cancers in Germany during the COVID-19 Pandemic: Fact or Fiction?","authors":"Henning Bahlburg, Patricia Rausch, Matteo Silberg, Karl Heinrich Tully, Sebastian Berg, Joachim Noldus, Marius Cristian Butea-Bocu, Burkhard Beyer, Guido Müller","doi":"10.1159/000544745","DOIUrl":"10.1159/000544745","url":null,"abstract":"<p><strong>Introduction: </strong>The COVID-19 pandemic interrupted many aspects of health care, including cancer treatment. This study aims to assess the potential impact of the COVID-19 pandemic on tumor stage migration in the three most common urological malignancies.</p><p><strong>Methods: </strong>Patient and tumor characteristics of patients undergoing inpatient rehabilitation (IR) in one dedicated IR center in 2019 (pre-pandemic) and 2021 (mid-pandemic) were retrospectively evaluated. The study focused on patients after radical prostatectomy (RP) for prostate cancer (PCa), radical cystectomy (RC) for bladder cancer (BCa), or (partial) nephrectomy for kidney cancer (KC).</p><p><strong>Results: </strong>Overall, 9,039 patients (6,898 (76.3%) after RP, 1,427 (15.8%) after RC, 714 (7.9%) after (partial) nephrectomy) were enrolled. A significant decrease of PCa patients suffering from Gleason sum score ≥8 (17.6% vs. 20.5%, p = 0.005) and lymph node metastases (10.9% vs. 13.0%; p = 0.012) was observed. In BCa and KC patients, tumor stage distribution and abundance of lymph node metastases remained stable, while significantly more BCa patients received neoadjuvant chemotherapy (10.4% vs. 20.2%, p = 0.001). Overall, a significant increase in robot-assisted surgery across all investigated malignancies was detected.</p><p><strong>Conclusions: </strong>No stage migration could be detected across the three most common urological malignancies during the COVID-19 pandemic. Therapeutic standards remained high, while oncological outcomes remained relatively unchanged.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Safety of GnRH Agonist-Based Androgen Deprivation Therapy in a Real-World Setting: Results from a Prospective Cohort Study (LEAN).","authors":"Bernd J Schmitz-Dräger, Ekkehardt Bismarck, Thomas Ebert, Roland Starlinger, Kerstin Dienes, Bertram Ottillinger, Peter J Goebell, Stephan Mühlich, Natalya Benderska-Söder, Jutta Bergler-Klein, Oliver W Hakenberg","doi":"10.1159/000543985","DOIUrl":"10.1159/000543985","url":null,"abstract":"<p><strong>Introduction: </strong>LEAN is a prospective, multicenter, noninterventional, German cohort study in patients with locally advanced and metastatic hormone-sensitive prostate cancer (PC). This analysis explores the efficacy and safety of leuprorelin in patients with PC and an indication for androgen deprivation therapy (ADT) in routine practice.</p><p><strong>Methods: </strong>Safety assessment focused on the incidence of major adverse cardiovascular (CV) events (MACEs; a composite of all-cause death, myocardial infarction, or stroke) over the 12-month study period. Patients initiating ADT before enrollment were excluded from the analysis.</p><p><strong>Results: </strong>Of the 1,372 patients included, MACEs occurred in 57 (4.2%) patients and in 18/532 (3.4%) versus 39/840 (4.6%) patients without and with a pre-existing CV comorbidity, respectively (p = 0.264). Of the 57 MACEs, 17 were CV events and 20 were considered PC-related events; in 20 patients, events were classed as \"other\" or the context remained unknown. Only one MACE, nonserious arrhythmia, was considered drug related by the urologist. Of the 52 deaths reported in patients with MACEs, 12 were related to a CV event and 20 were related to disease progression.</p><p><strong>Conclusion: </strong>In a large European patient cohort, leuprorelin-based ADT demonstrated an acceptable safety profile, with a low incidence of CV events.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Preferences and Fears: Misconceptions about Robotic-Assisted Surgery.","authors":"Christopher Hirtsiefer, Mandy Ehrt, Roman Herout, Sherif Mehralivand, Juozas Vilimas, Martin Baunacke, Christian Thomas","doi":"10.1159/000544773","DOIUrl":"10.1159/000544773","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Robotic-assisted surgery (RAS) is widely adopted across surgical fields, notably urology, but patient knowledge remains limited, often shaped by misconceptions. Previous research indicates factors like age, profession, and technology use influence RAS perceptions. This study investigates public knowledge, preferences, and misconceptions about RAS within a German cohort.</p><p><strong>Methods: </strong>A cross-sectional survey at a university hospital's open house gathered responses from 339 participants prior to an RAS exhibition. The questionnaire assessed demographics, surgical preferences, and RAS knowledge. Statistical analyses, including t tests, chi-squared tests, ANOVA, and multivariate logistic regression, identified key associations.</p><p><strong>Results: </strong>A total of 71% (234) of participants favored RAS over conventional surgery, yet misconceptions persisted in 38% (122), particularly among pensioners (48% (46), p < 0.01). Misconceptions were linked to a preference for conventional surgery (43% (52) vs. 19% (36), p < 0.01). Surgical preference emerged as a significant predictor of misconception. Concerns included surgeon skill (41%, 141) and machine malfunction (39%, 132), with younger participants fearing human error and older individuals fearing technical failure (p < 0.01).</p><p><strong>Conclusion: </strong>This local study reveals strong public support for RAS but underscores prevalent misconceptions, especially among older adults, suggesting that addressing misconceptions could foster acceptance and informed decision-making.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis between Aspiration and Laparoscopic Deroofing of Renal Cyst Management: A Prospective Randomized Controlled Study.","authors":"Ahmed Reda, Mohamed Ali Zarzour, Mohammad Faragallah","doi":"10.1159/000543440","DOIUrl":"10.1159/000543440","url":null,"abstract":"<p><strong>Introduction: </strong>Renal cysts are a common clinical finding necessitating a nuanced approach to management. This study explores outcomes and patient characteristics associated with two interventions for renal cysts: aspiration of renal cyst povidone-iodine sclerotherapy and laparoscopic renal cyst deroofing.</p><p><strong>Methods: </strong>A study was conducted on patients admitted to urology and nephrology hospital at Assiut University between February 2022 and December 2022. The study population included adult patients diagnosed with renal cysts. Data included demographic information, operative times, post-operative complications, and follow-up assessments.</p><p><strong>Results: </strong>Our findings revealed the effectiveness of single session povidone-iodine sclerotherapy with a high success rate of 95% and comparable to laparoscopic deroofing (98.3%); however, the patients who underwent laparoscopic deroofing had significantly longer operative times compared to those who underwent aspiration (p < 0.001). Gender did not significantly influence operative time (p = 0.583), but age exhibited a marginal association (p = 0.0667). The overall complications rate (over a period of 6 months) has no significant difference between the two groups. Re-do procedures were infrequent in both groups.</p><p><strong>Conclusion: </strong>This study showed the outcomes of two common interventions for renal cyst management. The effectiveness of a single session povidone-iodine sclerotherapy in management of symptomatic simple renal cyst in comparison to the gold standard technique of laparoscopic deroofing which is associated with longer operative times and more invasiveness. These insights can guide clinicians in selecting appropriate interventions and managing patient expectations.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-6"},"PeriodicalIF":1.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}