{"title":"The geriatric nutritional risk index as a predictor of outcomes in urological cancers: A systematic review and meta-analysis.","authors":"Yuefen Chen, Mei Wen, Zhe Yu, Fengjiao Xu","doi":"10.1159/000544793","DOIUrl":"https://doi.org/10.1159/000544793","url":null,"abstract":"<p><strong>Objective: </strong>The geriatric nutritional risk index (GNRI) is being used to predict outcomes of several malignancies. However, its utility for urinary tract cancer has not been systematically analyzed. We present the first meta-analysis examining the association between GNRI and the prognosis of urological cancers.</p><p><strong>Methods: </strong>This PROSPERO registered review searched Embase, PubMed, Web of Science, and Scopus up to 25th November 2024 for studies examining the relationship between GNRI and overall survival (OS), cancer-specific survival (CSS), and progression-free survival (PFS) after urological cancers.</p><p><strong>Results: </strong>A total of 20 studies were eligible. Three studies on bladder cancer, four on prostate cancer, seven on renal cell carcinoma (RCC), and six on urothelial cancers. Meta-analysis showed that low GNRI was a statistically significant predictor of poor OS in prostate cancer (OR: 3.02 95% CI: 1.61, 5.67). Pooled analysis showed that low GNRI was associated with poor OS (OR: 2.17 95% CI: 1.46, 3.22) and CSS (OR: 2.60 95% CI: 1.57, 4.30) in RCC but not PFS (OR: 1.50 95% CI: 1.00, 2.24). Pooled analysis also found that low GNRI was a predictor of worse OS (OR: 2.24 95% CI: 1.52, 3.29) and CSS (OR: 3.07 95% CI: 1.38, 6.86) in urothelial carcinoma. A narrative review on bladder cancer and GNRI showed mixed results.</p><p><strong>Conclusion: </strong>GNRI may have a role in predicting outcomes of urological malignancies. Low GNRI was independently associated with worse OS after prostate, renal cell, and urothelial carcinoma. Further, it also predicted CSS after RCC and urothelial carcinoma.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-19"},"PeriodicalIF":1.5,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rashid Al Sliman, Timur H Kuru, Julian P Struck, Anna L Heinrichs, Katharina Arndt, Johannes Salem, Hendrik Borgmann
{"title":"Usage of the Internet and Digital Health Among Urological Patients: Findings from a Cross-Sectional Study.","authors":"Rashid Al Sliman, Timur H Kuru, Julian P Struck, Anna L Heinrichs, Katharina Arndt, Johannes Salem, Hendrik Borgmann","doi":"10.1159/000544873","DOIUrl":"https://doi.org/10.1159/000544873","url":null,"abstract":"<p><strong>Introduction: </strong>The rising prevalence of internet usage and smartphone applications among urology patients underscores the critical role of digital health literacy. This study investigates the acceptability of digital health technologies among urology patients and identifies factors influencing their acceptance.</p><p><strong>Materials and methods: </strong>A cross-sectional, anonymous survey consisting of 12 questions was developed based on literature research. It was conducted online using SurveyMonkey and targeted patients in the CUROS network in Germany. The Data were analysed descriptively using SPSS.</p><p><strong>Results: </strong>Of 1,039 participants, 99.1% reported using the internet, with 84.4% using it several times daily. YouTube emerged as the most popular social media platform. While 90.2% searched for health information online, trust in online resources was low (mean score 4.63). Only 35.2% used medical apps, but 62.8% expressed willingness to use them if prescribed. Furthermore, 74.2% supported the use of electronic patient records (EPRs), although concerns regarding privacy were noted.</p><p><strong>Conclusions: </strong>Urology patients demonstrate a high engagement with digital resources but express concerns about the reliability of online health information. Enhancing education on digital health tools and fostering trust in these resources is essential for improving patient outcomes and encouraging the integration of digital health in urological care.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-17"},"PeriodicalIF":1.5,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philipp Reimold, Luisa Bourgeois, Lia Klefenz, Marius Christian Butea-Bocu, Anna Lena Jacobi, Luka Flegar, Christer Groeben, Johannes Huber
{"title":"Intraindividual perception of open vs. robot-assisted partial nephrectomy (PERCEPTION trial): An important complementing perspective to randomized controlled trials.","authors":"Philipp Reimold, Luisa Bourgeois, Lia Klefenz, Marius Christian Butea-Bocu, Anna Lena Jacobi, Luka Flegar, Christer Groeben, Johannes Huber","doi":"10.1159/000545583","DOIUrl":"https://doi.org/10.1159/000545583","url":null,"abstract":"<p><p>Introduction Randomized controlled trials comparing patients' experience with open (OPN) vs. robot-assisted partial nephrectomy (RAPN) showed no clear advantages for RAPN. This contradicts our clinical impression, so we analyzed a cohort that underwent both approaches for bilateral renal tumors. The aim of our study was to compare their intraindividual perceptions of OPN and RAPN. Methods Scar assessment and evaluation of patient-reported outcome measures (PROMs) were conducted. The questionnaires were retrospectively answered for postoperative day 5 after OPN and RAPN and, as a reference, for the date of presentation. Results Results revealed longer hospitalization and ischemia times in patients with OPN, while ratings for physical condition and quality of life were better in the RAPN group. Stress, depression, and anxiety in cancer patients scored higher in the OPN group. Scar assessment revealed less patient-reported satisfaction after OPN. Patients favored RAPN when comparing both approaches directly and were strongly favored recommending RAPN to a friend. Conclusion This is the first study on the intraindividual perception of OPN vs. RAPN, revealing a comparative judgment clearly in favor of RAPN. Based on our findings, we designed the APPROACH trial to compare OPN and RAPN in a representative population under the conditions of routine care.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-17"},"PeriodicalIF":1.5,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chen Zhu, Long Ma, Xuehua Chen, Yue Zhou, Yunfei Wei, Ping Zhou, Ninghong Wang, Jian Su, Lin Yuan, Yan Xu
{"title":"Bladder stone composition in JiangSu region of China: results from 421 stone analyses.","authors":"Chen Zhu, Long Ma, Xuehua Chen, Yue Zhou, Yunfei Wei, Ping Zhou, Ninghong Wang, Jian Su, Lin Yuan, Yan Xu","doi":"10.1159/000542255","DOIUrl":"https://doi.org/10.1159/000542255","url":null,"abstract":"<p><strong>Introduction: </strong>Accurate analysis of bladder stone composition is essential for appropriate treatment planning and recurrence prevention. The aim of this study was to evaluate the characteristics of bladder stone components in our center.</p><p><strong>Materials and methods: </strong>A retrospective analysis on the composition of bladder stones collected in our center from January 2014 to March 2023 was conducted in the present work. Age, sex and laboratory examination of all patients were collected. Infrared spectroscopy was conducted for stone analysis.</p><p><strong>Results: </strong>The most common stone component was calcium oxalate (43.0%), followed by uric acid (UA) stone (35.4%), calcium phosphate (12.10%), infection stone (9.0%) and cystine (0.5%). The highest stone prevalence appeared in patients aged over 60 years, and increased progressively with age. Furthermore, patients with UA stones were more likely to have a lower urinary pH. Additionally, patients with infection stones showed higher incidence of urinary tract infections than those with other types of stones. Patients with UA stones had higher average serum UA and creatinine levels. Uric acid stones are more likely to form multiple stones compared to stones of other composition. The volume of infectious stones is larger compared to stones of other compositions.</p><p><strong>Conclusions: </strong>This study highlights the importance of gaining a deeper understanding of bladder stone composition, as it can lead to more effective evaluation, treatment, and prevention of stone disease.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-12"},"PeriodicalIF":1.5,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Urinary Pleural Effusion:Introducing Treatment and Follow-Up Course of Three Cases.","authors":"Longyuhe Yang, Xuanfan Hu, Yueqiang Wang, Yu Tian, Zhen Ma, Qiuyi Lu, Yunliang Zhao, Jianbin Yang, Zhigang Zhang","doi":"10.1159/000545416","DOIUrl":"https://doi.org/10.1159/000545416","url":null,"abstract":"<p><p>Urinary-derived pleural effusion is a rare thoracic complication of urogenital diseases, most commonly caused by obstructive urinary tract disorders.However, it may also result from therapeutic or traumatic injuries. Due to its rarity and lack of clear diagnostic criteria, such conditions are often underestimated. In the three reported cases, all patients exhibited typical clinical symptoms, including dyspnea and chest pain. After the diagnosis of urinary-derived pleural effusion, different treatment strategies have been successfully employed to manage the condition. During follow-up, all three patients underwent surgery again for urinary calculi, but did not experience similar severe complications. We emphasize that the management of urinary-derived pleural effusion requires multidisciplinary collaboration that focuses on correcting the underlying urological pathologies. Once treated for a patent of the urinary tract, pleural effusion typically resolves rapidly. Based on these cases, we highlight the importance of early diagnosis and appropriate treatment in the management of urinary-derived pleural effusion, and recommend that clinicians maintain a high index of suspicion when encountering related cases to develop individualized treatment plans.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-14"},"PeriodicalIF":1.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emre Sam, Ömer Uslu, Ahmet Erkan Bilici, Mehmet Sefa Altay
{"title":"Anterior Urethral Paraganglioma: An Extremely Rare Case Report and Literature Review.","authors":"Emre Sam, Ömer Uslu, Ahmet Erkan Bilici, Mehmet Sefa Altay","doi":"10.1159/000545412","DOIUrl":"https://doi.org/10.1159/000545412","url":null,"abstract":"<p><strong>Introduction: </strong>Urinary tract paragangliomas account for less than 1% of all paragangliomas and are most commonly seen in the bladder, with the prostate being the second most common localization. However, urethral paragangliomas are extremely rare.</p><p><strong>Case presentation: </strong>A 52-year-old male patient admitted to the urology clinic with lower urinary tract symptoms (LUTS), including poor and intermittent stream, straining, frequency, and nocturia. A pedunculated polypoid lesion, approximately 1 cm in size, was detected at the level of the bulbar urethra and was excised from its stalk using cold cup forceps. A diagnosis of paraganglioma was made on histopathological examination.</p><p><strong>Conclusion: </strong>Anterior urethral paraganglioma can cause LUTS even if small due to urethral calibration. The recommended treatment method is endoscopic excision of the lesion. Paraganglioma should be kept in mind in the differential diagnosis of urethral lesions.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of 3D Reconstruction Combined with Engineering Software Analysis of Pelvic Floor Muscle Morphology on Sexual Dysfunction in Patients with Pelvic Organ Prolapse.","authors":"Lifan Shen, Huijun Bai","doi":"10.1159/000545009","DOIUrl":"https://doi.org/10.1159/000545009","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the relationship between the deformation of pelvic floor muscles, which primarily participate in sexual activity, in non-prolapse patients compared to those with pelvic organ prolapse (POP), using MRI combined with 3D reconstruction and engineering software.</p><p><strong>Methods: </strong>This study retrospectively analyzed 100 patients with sexual activity needs, including 53 diagnosed with POP and 47 without POP. MRI images of relevant pelvic floor muscles were reconstructed in 3D using Mimics software. The IGS models generated with Geomagic Wrap software were assigned material properties and analyzed in SolidWorks. The muscle models were transformed into visualized solid models, yielding results for mass, volume, and surface area of the pelvic floor muscles involved in sexual activity. These parameters were visualized among POP and non-POP patients, allowing for a comparative analysis.</p><p><strong>Result: </strong>Significant differences (P<0.05) were observed between the two groups in terms of the volume, mass, and measurable thickness range (thicker regions) of the bulbospongiosus muscle, as well as the surface area of the pubococcygeus muscle and the levator ani.</p><p><strong>Conclusion: </strong>By using 3D reconstruction and engineering software to visualize muscle models, morphological changes in the bulbospongiosus, pubococcygeus, and levator ani muscles are highlighted. This study lays a theoretical foundation for understanding the functional factors contributing to sexual dysfunction in patients with POP.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-16"},"PeriodicalIF":1.5,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Flexible-Tip and Non-Flexible Ureteral Access Sheaths for Treatment of Renal Lower Calyx Stones.","authors":"Zhiyong Xiong, Chen Li, Keming Huang, Zhen Han, Shuai Wu","doi":"10.1159/000545070","DOIUrl":"https://doi.org/10.1159/000545070","url":null,"abstract":"<p><strong>Introduction: </strong>To compare the efficacy of a flexible-tip ureteral access sheath (F-UAS) with a traditional non-flexible ureteral access sheath (T-UAS) in the treatment of renal lower calyx stones.</p><p><strong>Methods: </strong>This retrospective analysis included clinical data from patients with unilateral renal lower calyx stones who underwent treatment with either a f-UAS (cases from December 2023 to September 2024) or a T-UAS (cases from January 2023 to November 2023). Inclusion criteria were ages 18-75 years, lower pole kidney stones measuring 1-2 cm. The primary outcome was the immediate postoperative stone-free rate (SFR) on the first day post-surgery. Secondary outcomes included operative time, postoperative complications, postoperative hospital stay, and three-month SFR.</p><p><strong>Results: </strong>A total of 132 patients were included in the study, with 63 in the F-UAS group and 69 in the T-UAS group. Baseline characteristics were comparable between groups. The F-UAS group demonstrated a significantly higher day-1 postoperative SFR (73.0% vs. 17.4%; P < 0.001). The overall complication rate was lower in the F-UAS group (P = 0.031), with a notably reduced incidence of postoperative fever. The F-UAS group also had a significantly lower basket usage rate (20.6% vs. 100%; P < 0.001). There were no significant differences in operative time or three-month SFR between the groups (P = 0.097 and P = 0.354, respectively). Hospital stay and stone composition were also similar between groups.</p><p><strong>Conclusion: </strong>Compared to T-UAS, the use of F-UAS for retrograde intrarenal surgery in the treatment of renal lower calyx stones is associated with a higher day-1 SFR. Additionally, the F-UAS group demonstrated reduced basket usage and fewer postoperative complications.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmet Burak Yilmaz, Tolga Karakan, Bugra Bilge Keseroglu
{"title":"A Comprehensive Analysis of Surgically Treated Renal Tumor Characteristics in Turkey: Nationwide Study.","authors":"Ahmet Burak Yilmaz, Tolga Karakan, Bugra Bilge Keseroglu","doi":"10.1159/000545292","DOIUrl":"10.1159/000545292","url":null,"abstract":"<p><strong>Introduction: </strong>To evaluate the kidney tumor characteristics in surgically treated patients in Turkey.</p><p><strong>Methods: </strong>Patients who underwent surgical treatment for kidney tumors between January 2017 and December 2022 in Turkey were retrospectively reviewed through the Health Information Systems of the Ministry of Health. Patient's age, gender, comorbidities, surgical methods, and tumor characteristics were evaluated.</p><p><strong>Results: </strong>The most common subtype of RCC was clear cell RCC(ccRCC) in 4892 patients (72%). Papillary RCC (pRCC) was less frequent in patients under 50, with its incidence increasing with age compared to other subtypes (p=0.006). There was a significant relationship was found between hypertension and pathological subtypes (p=0.002), with pRCC and unclassified RCC contributing to this difference. Among RCC subtypes, as the ISUP/Fuhrman grade increased, the tumor stage also progressed (p<0.001). Tumors in males and tumors in the left kidney were at more advanced cancer at the time of diagnosis (p<0.001 and p=0.006, respectively). In multivariate logistic regression analysis, advanced age (Odds Ratio [OR]: 1.007, 95% Confidence Interval [CI]: 1.001-1.014, p=0.04), male gender (OR:0.416, %95 CI:0.350-0.493, p<0.001), increased tumor size (OR:1.117, 95% CI: 1.079-1.156, p<0.001), and the presence of diabetes mellitus (OR:1.222, 95% CI:1.007-1.483, p=0.042) were found to be independent risk factors for malignancy.</p><p><strong>Conclusions: </strong>Our study identifies key factors associated with surgically treated renal tumors in Turkey. While aligning with prior research, these findings highlight the need for detailed studies to clarify the impact of biological, demographic, and lifestyle factors on RCC risk and progression, enabling more accurate diagnosis and tailored treatment.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-13"},"PeriodicalIF":1.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}