Urologia Internationalis最新文献

{"title":"Adjustable Transobturator Male System (ATOMS) in Artificial Urinary Sphincter patients - a good Alternative?","authors":"Marc Kidess, Elisa Lederer, Troya Georgieva, Julian Hermans, Leo F Stadelmeier, Marina Hoffmann, Nikolaos Pyrgidis, Julian Marcon, Philipp Weinhold, Patrick Keller, Michael Chaloupka, Benedikt Ebner, Daniel Puhr-Westerheide, Ricarda M Bauer, Christian Stief, Yannic Volz","doi":"10.1159/uin/aewag023","DOIUrl":"https://doi.org/10.1159/uin/aewag023","url":null,"abstract":"<p><strong>Introduction: </strong>Post-prostatectomy stress urinary incontinence (SUI) significantly impairs patients' quality of life. While the artificial urinary sphincter (AUS) is considered the gold standard for managing severe SUI, a subset of patients is not suitable for this intervention. This study aimed to evaluate the clinical outcomes of patients who received an adjustable transobturator male system (ATOMS) as an alternative to AUS for the treatment of SUI.</p><p><strong>Methods: </strong>In this single-center retrospective study, we included 25 patients who received ATOMS implantation for post-prostatectomy SUI, despite being technically eligible for AUS based on incontinence severity and pelvic floor status. Primary outcomes included pad usage, continence rates, complications, and patient-reported satisfaction. A cross-sectional follow-up was conducted in using standardized questionnaires.</p><p><strong>Results: </strong>Median age was 74.0 years; 60% of patients had undergone pelvic radiotherapy. Preoperative median pad usage was 6.0/day, reduced to 3.0/day postoperatively. Social continence (≤1 pad/day) was achieved in 16%, and ≥50% reduction in pad usage in 76% of patients. Complications were mostly minor. Cross-sectional follow-up data were available for 60% of patients at a median of 42 months. Patient satisfaction was high (73.3%), and 80% would recommend the procedure. According to the PGI score, 73.3% reported \"very much\" or \"much improved\" outcomes.</p><p><strong>Conclusion: </strong>ATOMS represents a feasible and safe treatment alternative for patients with severe SUI who are unable or unwilling to undergo AUS implantation. Despite suboptimal continence outcomes compared to AUS, high satisfaction and acceptable complication rates support its use in appropriately selected patients.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic Lymph Node Dissection at Radical Prostatectomy: Patterns of Failure and Decision Impact.","authors":"Steffen Lebentrau, Ingmar Wolff, Christian Gilfrich, Matthias May","doi":"10.1159/uin/aewag025","DOIUrl":"https://doi.org/10.1159/uin/aewag025","url":null,"abstract":"","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of the Safety and Efficacy of Endoscopy-Assisted Supine Percutaneous Nephrolithotomy Versus Standard Supine Percutaneous Nephrolithotomy: A Randomized Prospective Study.","authors":"Joshgun Huseynov, Deniz Noyan Özlü, Feyzi Arda Atar, Ali Ihsan Tasci","doi":"10.1159/uin/aewag022","DOIUrl":"https://doi.org/10.1159/uin/aewag022","url":null,"abstract":"<p><strong>Objective: </strong>To compare the safety and efficacy of endoscopy-assisted supine percutaneous nephrolithotomy (ePNL) with standard supine percutaneous nephrolithotomy (sPNL).</p><p><strong>Materials and methods: </strong>This study included patients aged over 18 with a stone size of ≥2 cm, an American Association of Anesthesiology score of ≤3, and a body mass index of ≤35 who underwent ePNL or sPNL at our hospital between February 2021 and August 2021. Eligible patients, selected based on inclusion and exclusion criteria, were randomized using a computer-generated random table. Perioperative and postoperative data were compared between the two groups.</p><p><strong>Results: </strong>A total of 60 patients were included in the study. Demographic data and stone characteristics were similar between the groups. The access fluoroscopy time (AFT) was comparable between the groups; however, the total fluoroscopy time (TFT) was significantly shorter in the ePNL group (31.5 seconds vs. 197.5 seconds, p<0.0001). The amount of bleeding, assessed by hemoglobin drop, was higher in the sPNL group (p=0.038). The success rate of guidewire placement into the ureter after access was higher in the supine ePNL group compared to the sPNL group (66.6% vs. 36.6%, p=0.038). There was no statistically significant difference in overall complication rates between the groups (p=0.272). Stone-free rates were 86.6% for ePNL and 80% for sPNL (p=0.488).</p><p><strong>Conclusion: </strong>The ePNL method is a safe and effective technique characterized by less bleeding, shorter fluoroscopy time, and successful guidewire placement into the ureter, with similar success and complication rates to sPNL.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Care After Transurethral Resection (TURP and TURBT): Early Mobilization, Activity Restriction, and Convalescence - A Scoping Review.","authors":"Patrick Betschart, Jessica Rührup, Mark Meier, Alberto Piller, Thomas Leippold, Carlo Camathias","doi":"10.1159/uin/aewag021","DOIUrl":"https://doi.org/10.1159/uin/aewag021","url":null,"abstract":"<p><strong>Background: </strong>TURP and TURBT are among the most frequently performed urological procedures; laser alternatives such as HoLEP are increasingly adopted. Patients are routinely advised to restrict postoperative activity, yet recommendations conflate immediate mobilization (hours to days) with medium-term convalescence restrictions (weeks).</p><p><strong>Objective: </strong>To map the evidence linking postoperative activity to complications and recovery after TURP, TURBT, and laser-based transurethral procedures.</p><p><strong>Methods: </strong>PRISMA-ScR scoping review. PubMed, Scopus, Embase and ClinicalTrials.gov were searched (1 June 2026); a supplementary PubMed search (July 2026) targeted UTI, orchitis/epididymitis, anticoagulation, and frailty. Records were screened by title/abstract and charted descriptively.</p><p><strong>Results: </strong>Of 263 records, 31 were charted (5 directly relevant, 26 contextual); the supplementary search added 10 contextual sources. No trial compared activity restriction with early mobilization using surgical complication endpoints. No data linked activity level to UTI or orchitis/epididymitis after transurethral resection. ERAS studies incorporating early mobilization showed improved or unchanged recovery without increased complications. All direct evidence addresses the immediate postoperative phase; no study examined medium-term convalescence restrictions. Frailty, comorbidities, and anticoagulation are relevant risk modifiers but unstudied in relation to activity.</p><p><strong>Conclusions: </strong>Direct evidence on postoperative activity after transurethral resection is absent; ERAS data support early mobilization within multimodal bundles. Future research should separate immediate mobilization from convalescence, include infectious endpoints, and incorporate patient-level factors such as frailty and anticoagulation.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-specific impact of neurogenic lower urinary tract dysfunction on quality of life - a cross-sectional study.","authors":"Jürgen Pannek, Jasmin Lea Mahler, Jens Woellner, Joerg Krebs","doi":"10.1159/uin/aewag013","DOIUrl":"https://doi.org/10.1159/uin/aewag013","url":null,"abstract":"<p><strong>Introduction: </strong>The assessment of neurogenic lower urinary tract dysfunction (NLUTD) should include objective and quality of life (QoL) measures, considering sex and gender differences. Thus, we investigated the sex-specific impact of NLUTD on QoL.</p><p><strong>Methods: </strong>We evaluated consecutive outpatients with chronic NLUTD, who had completed the Short Form (SF-)Qualiveen questionnaire between 09/2024 and 01/2026 at a specialized spinal cord injury center, in a cross-sectional study. Patient characteristics and urodynamic parameters were retrieved from patient charts. Treatment success and risk for renal damage were determined based on urodynamic data. The effects of sex, age, bladder evacuation method, urinary incontinence, urinary tract infections and treatment success on SF-Qualiveen overall and domain scores were analyzed.</p><p><strong>Results: </strong>Data of 113 patients (48 females, 65 males) were analyzed. Mean age was 60.6±12.9 years in females and 61.2±12.4 years in males. Mean NLUTD duration was 21.8±15.1 years in females and 22.1±16.9 years in males. In most patients, NLUTD treatment was successful (77.0%), and no risk for renal damage was present (89.4%). The median overall SF-Qualiveen score was 1.125 (0.625 / 1.844). There were no significant (p>0.11) differences between the sexes in the different QoL scores. Only urinary incontinence had a significant (p=0.04) effect on QoL scores. Patients with urinary incontinence had a significantly (p=0.01) greater overall QoL score (median 1.75, 1.125 / 2.125) compared to those without incontinence (median 1.0, 0.625 / 1.5).</p><p><strong>Conclusion: </strong>In patients with adequately treated NLUTD, there were no sex-specific differences in QoL. However, urinary incontinence had a negative impact on QoL.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Early Treatment Response in mCSPC Using KELIM PSA Score: Implications for Survival.","authors":"Semiha Urvay, Ismail Beypinar, Onur Yazdan Balcik, Muslih Urun, Berrak Mermit Ercek, Hacer Demir, Canan Sarikaya Yildiz, Murat Araz, Ahmet Oruç, Yusuf Ilhan, Aziz Kurtulus","doi":"10.1159/uin/aewag017","DOIUrl":"https://doi.org/10.1159/uin/aewag017","url":null,"abstract":"<p><strong>Purpose: </strong>The prognostic value of the PSA ELIMination rate constant K (KELIM PSA) score was investigated in patients with metastatic castration-sensitive prostate cancer (mCSPC) treated with docetaxel in combination with ADT.</p><p><strong>Methods: </strong>This multicenter retrospective study included 105 patients diagnosed with prostate adenocarcinoma who received first line docetaxel in combination with ADT for mCSPC. The KELIM score was calculated using PSA kinetics modeled with a nonlinear mixed-effects model. Patients with KELIM PSA<1 were categorized as unfavorable, whereas those with KELIM PSA≥1 were considered favorable.</p><p><strong>Results: </strong>A total of 105 patients were included in the study. There were 53 and 52 patients in the favorable KELIM PSA and unfavorable KELIM PSA groups, respectively. Favorable KELIM PSA patients having a median OS of 44 months compared to 24 months for those with unfavorable KELIM PSA. One-, three-, and five-year OS rates were higher in the favorable KELIM PSA group. In the univariate analysis, ECOG≥2, older age, liver metastasis, and unfavorable KELIM score were associated with worse OS. However, in the multivariable analysis, only definitive treatment and advanced age remained independent prognostic factors for OS.</p><p><strong>Conclusion: </strong>The KELIM PSA score may serve as a simple, effective, and inexpensive prognostic tool for assessing early treatment responses and predicting disease progression in patients with mCSPC treated with docetaxel.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Classic Transverse Incision MicroTESE and Modified Mini-Incision MicroTESE in Non-Obstructive Azoospermic Patients.","authors":"Mehmet Sefa Altay, Adem Utlu, Tugay Aksakalli, Ahmet Emre Cinislioglu, Emre Sam, Fevzi Bedir, Hüseyin Kocatürk, Ibrahim Karabulut, Saban Oguz Demirdogen, Isa Ozbey","doi":"10.1159/uin/aewag008","DOIUrl":"https://doi.org/10.1159/uin/aewag008","url":null,"abstract":"<p><strong>Objective: </strong>Non-obstructive azoospermia (NOA) primarily due to impaired spermatogenesis. Microdissection testicular sperm extraction (mTESE) is the gold standard for sperm retrieval in NOA patients. We compared sperm retrieval rates (SRR), operative time, and postoperative outcomes between classic transverse incision microTESE (CTI) and modified mini-incision microTESE (MMI).</p><p><strong>Methods: </strong>In this retrospective study, 59 men with NOA underwent either CTI (n=33) or MMI (n=26) between 2021 and 2024. Preoperative and postoperative parameters, including SRR, operative time, complications, testosterone levels, testicular volume, and histopathology, were analyzed. Statistical analyses were performed using IBM SPSS Statistics version 21.</p><p><strong>Results: </strong>SRR was 34.6% in MMI and 39.4% in CTI (p=0.706). Operative time (46.5 ± 7.9 min vs. 64.7 ± 14.5 min, p=0.001) and postoperative pain scores (VAS 2.9 ± 0.7 vs. 4.4 ± 0.5, p=0.001) were significantly lower in MMI. No complications were observed. Histology revealed Sertoli cell-only syndrome in 14 and 19 patients in MMI and CTI groups, respectively; the remainder had maturation arrest or hypospermatogenesis. No complications such as infection, sperm granuloma, or androgen deficiency were observed in either group.</p><p><strong>Conclusion: </strong>SRR was comparable between techniques. MMI was associated with shorter operative times and reduced postoperative discomfort.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gleason 6 Prostate Cancer: Predictors of Upgrading in a High-Volume Turkish Tertiary Center.","authors":"Fatih Bicaklioglu, Yigit Akyol, Mahmut Selman Mert, Bilal Eryildirim","doi":"10.1159/uin/aewag006","DOIUrl":"10.1159/uin/aewag006","url":null,"abstract":"<p><strong>Introduction: </strong>Gleason score 6 prostate cancer is generally considered a low-risk disease; however, pathological upgrading after radical prostatectomy remains frequent and clinically relevant. Reliable preoperative predictors are needed to improve risk stratification and treatment decision-making, particularly in populations with limited access to advanced imaging.</p><p><strong>Methods: </strong>We retrospectively analyzed 338 patients with biopsy-confirmed Gleason score 6 prostate adenocarcinoma who underwent radical prostatectomy between 2013 and 2025 at a tertiary referral center in Turkey. Clinical, biopsy, and imaging variables were assessed. Independent predictors of upgrading were identified using multivariable logistic regression analysis, and model performance was evaluated using receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>Gleason score upgrading occurred in 193 patients (57.1%). Patients with upgrading had significantly higher prostate-specific antigen (PSA) levels, higher PSA density values, and smaller prostate volumes (all p < 0.05). Adverse pathological features, including extracapsular extension, seminal vesicle invasion, and positive surgical margins, were more frequent in the upgraded group (all p < 0.01). PSA density (OR 40.07 per 1 unit increase, p = 0.001) and age (OR 1.05 per 1 year increase, p = 0.016) were identified as independent predictors of upgrading. A PSA density cut-off value of 0.125 yielded a sensitivity of 69.9% and a specificity of 48.3% (area under the curve = 0.622).</p><p><strong>Conclusion: </strong>Gleason score upgrading is common among patients with biopsy Gleason 6 prostate cancer. PSA density and age were independently associated with pathological upgrading, whereas traditional biopsy tumor burden parameters appeared to have limited predictive value. Although a PSA density threshold of 0.125 demonstrated only modest discriminative ability, PSA density may provide additional information as an adjunct to preoperative risk assessment among surgically treated patients.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in Perioperative, Postoperative, Histological, and Early Functional Outcomes during Curricular and Non-Curricular Training for Robot-Assisted Radical Prostatectomy: A One-To-One Surgeon Comparison.","authors":"Nikolaos Liakos, Markus Grabbert, Nikolaos Pyrgidis, Christian Gratzke, Christian Wagner, Dalibor Bockelmann","doi":"10.1159/uin/aewag009","DOIUrl":"10.1159/uin/aewag009","url":null,"abstract":"<p><strong>Introduction: </strong>Robot-assisted radical prostatectomy (RARP) is one of the main options for the surgical treatment of localized prostate cancer. Following the standardization and establishment of the procedure as a routine surgical approach, formal training curricula were introduced to provide structured education for future console surgeons. However, a considerable number of surgeons continue to be trained outside of these standardized programs. This study aimed to compare the perioperative, postoperative, histopathological, and early functional outcomes of two surgeons who underwent different types of training: curriculum-based training (CC) versus non-curriculum-based (hybrid) training (non-CC).</p><p><strong>Materials and methods: </strong>We performed a retrospective analysis of the surgical outcomes of two surgeons trained through different pathways in two separate centers. One surgeon completed formal curriculum-based training in accordance with the EAU/ERUS guidelines for the standardized modular training for RARP, while the other followed a hybrid, non-curricular training model. We evaluated key outcome parameters through a multivariable regression analysis adjusted for age, T-status, and prostate volume.</p><p><strong>Results: </strong>A total of 83 patients were included, with 47 operated by the CC surgeon and 36 by the non-CC surgeon. Baseline characteristics were comparable between groups, except for higher initial PSA levels in the non-CC group (p = 0.023) and a more favorable Gleason score distribution in the CC group (p = 0.005). In the multivariate analysis, the CC group showed a significantly shorter hospital stay (median 6 versus 8 days, p < 0.001) and superior early postoperative continence (81% versus 56%, p = 0.02). Positive surgical margins were significantly less frequent in the CC group (4.3% versus 33%, p = 0.03). No significant differences were observed in estimated blood loss, transfusion rates, or major complications. Three-month continence outcomes were similar between groups.</p><p><strong>Conclusion: </strong>A curriculum-based surgical training pathway can lead to improved outcomes for patients undergoing RARP. Standardized surgical education should serve as the foundation for training in the field of robot-assisted surgery. Further studies are needed due to selection bias and temporal asymmetry of the cohorts of this study.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148851640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Well-differentiated Papillary Mesothelial Tumor of Tunica Vaginalis: A Case Report.","authors":"Yuko Ueda, Kazutomo Kuwata, Hiroshi Toge, Kanako Sagan, Yasuo Kohjimoto","doi":"10.1159/uin/aewag019","DOIUrl":"https://doi.org/10.1159/uin/aewag019","url":null,"abstract":"<p><strong>Introduction: </strong>Well-differentiated papillary mesothelial tumor (WDPMT) of the tunica vaginalis is an extremely rare entity that was recently reclassified by the World Health Organization.</p><p><strong>Case presentation: </strong>We report a case of WDPMT in which intraoperative frozen section analysis suggested a malignant tumor, leading to radical orchiectomy. Postoperative histopathological examination demonstrated papillary mesothelial proliferation with retained BAP1 and MTAP expression, supporting the diagnosis of WDPMT.</p><p><strong>Conclusion: </strong>This case highlights the diagnostic challenges of WDPMT during surgery and the limitations of intraoperative frozen section analysis.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1"},"PeriodicalIF":1.2,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148832840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}