Urologia Internationalis最新文献

{"title":"Direct vision internal urethrotomy in the management of bulbar urethral strictures: long term follow up and factors predicting treatment failure.","authors":"David Hernández-Hernández, María Yanira Ortega-González, Bárbara Padilla-Fernández, Irene Díaz-González, Julia Climent-González, Stephany Hess-Medler","doi":"10.1159/000543674","DOIUrl":"10.1159/000543674","url":null,"abstract":"<p><strong>Introduction: </strong>Evaluation of long term results, risk factors for treatment failure and complications in a contemporary cohort of patients with bulbar urethral strictures managed with direct vision internal urethrotomy (DVUI).</p><p><strong>Methods: </strong>We retrospectively reviewed 140 consecutive patients who underwent internal urethrotomy in a single institution between January 2012 and October 2020, with a minimum follow up of 24 months. Most urethral strictures had a iatrogenic origin (89.3%), length under 2 cm (75%) and were located at the mid-bulbar urethra (56.4%). Main variable was treatment failure, defined as recurrent urethral stricture at the same location in urethrography or urethroscopy, or the need of dilation, internal urethrotomy or open urethral reconstruction. Secondary variables analysed were length of stricture, suspected etiology, previous endoscopic procedures, hospital stay, days of catheterization and postoperative complications such as infections or haematuria.</p><p><strong>Results: </strong>Treatment failure occurred in 61.4% patients (104). Idiopathic strictures and those under 2 cm had better outcomes. Strictures longer than 2 cm and those with previous endoscopic procedures demonstrated a higher failure rate. More than 90% of recurrences occurred within the first two years of follow up. Complications of DVIU were scarce with postoperative urinary tract infection/urosepsis in 5.7% and prolonged haematuria in 10%. Mean hospital stay was 2.9 days.</p><p><strong>Conclusion: </strong>DVIU is a safe and simple technique, with reasonable efficacy in primary cases of bulbar urethral strictures under 2 cm length. Strictures longer than 2 cm or recurrent cases might be better approached through drug-coated balloon dilation or open urethral reconstruction. Follow up after DVIU must be at least 24 months.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mayo Adhesive Probability Score: A Reliable Predictor for Percutaneous Nephrolithotomy in Obese Patients?","authors":"Ali Ayranci, Ufuk Caglar, Huseyin Burak Yazili, Ufuk Can Aksu, Omer Sarilar, Faruk Ozgor","doi":"10.1159/000545180","DOIUrl":"10.1159/000545180","url":null,"abstract":"<p><p>Purpose This study evaluates the predictive value of the Mayo Adhesive Probability (MAP) score for surgical outcomes in obese patients undergoing miniaturized percutaneous nephrolithotomy (m-PCNL). The primary research question is whether the MAP score can predict intraoperative and postoperative complications in patients with a body mass index (BMI) greater than 30. Methods A retrospective analysis was conducted on patients who underwent m-PCNL at a tertiary care center between August 2018 and August 2023. Patients with kidney stones larger than 2 cm and a BMI >30 were included. They were categorized based on MAP scores (<3 vs. ≥3). Data on operation time, fluoroscopy time, hospital stay, and complications were compared. Statistical analyses included t-tests, chi-square tests, and logistic regression to assess risk factors for postoperative fever. Results Among 87 patients, those with a MAP score ≥3 had a significantly higher rate of postoperative fever (17.1% vs. 3.8%, p = 0.035). There were no significant differences between groups in operation time, fluoroscopy time, hospital stay, or blood transfusion needs. Logistic regression showed that a higher MAP score (OR: 6.614, p = 0.045) and increased stone burden (OR: 1.003, p = 0.040) were significant predictors of postoperative fever. Conclusion The MAP score is a significant predictor of postoperative fever in obese patients undergoing m-PCNL. Higher MAP scores are associated with a greater risk of fever, suggesting that careful monitoring and preventive measures are essential for patients with higher MAP scores. Further multicenter studies are needed to validate these findings and improve predictive accuracy.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical features and outcomes of congenital anterior urethrocutaneous fistula: A case series study.","authors":"Haijun Zhong, Hongquan Geng, Bin Zhang","doi":"10.1159/000545206","DOIUrl":"https://doi.org/10.1159/000545206","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the clinical features and prognosis of congenital anterior urethrocutaneous fistulas (CAUF) patients.</p><p><strong>Methods: </strong>This is a retrospective chart review of patients diagnosed with CAUF and underwent surgical repair by the author between October 2017 and December 2021 that was performed at a single tertiary-care institution. The medical records of CAUF patients were reviewed to evaluate their clinical characteristics and outcomes.</p><p><strong>Results: </strong>Eleven patients with CAUF were included. The median age of the patients was 41 months (11-84 months) months. Subcoronal fistulas were observed in 1 patient, midpenile shafts in 7 patients, proximal penile to subcoronal fistulas in 2 patients, and perineum to penile fistulas in 1 patient. Associated urinary system anomalies were found in 3 patients, and other anomalies were found in 2 patients. One-stage surgery was performed in 10 patients, and staged surgery was performed in one patient. There were no postoperative complications, and there was good voiding.</p><p><strong>Conclusions: </strong>Although CAUF often coexists with genitourinary or other deformities, it has a good prognosis following an appropriate surgical strategy for each patient.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ureteroplasty for the repair of ureteral stricture using lingual mucosa and buccal mucosa grafts：a meta-analysis.","authors":"Xin Zeng, Lingyu Xie, Zhicheng Zeng, Yuanhu Yuan, Hui Xu","doi":"10.1159/000545041","DOIUrl":"https://doi.org/10.1159/000545041","url":null,"abstract":"<p><p>The study aims to analyze the outcomes of buccal mucosa and lingual mucosa graft reconstruction for repairing ureteral strictures, assessing the efficacy and safety of both surgical approaches.</p><p><strong>Methods: </strong>A computer search was conducted on PubMed, Embase, and Web of Science using keywords such as \"buccal mucosa\", \"lingual mucosa\", \"oral mucosa\", \"ureteral stenosis\", and \"ureteral reconstruction\" to gather relevant literature on lingual mucosa and the efficacy of buccal mucosal reconstruction for ureteral repair. The search spanned from January 2000 to March 2024, focusing on experiments that assessed LMGU (lingual mucosa graft ureteroplasty) or BMGU (buccal mucosa graft ureteroplasty). Variables examined included reconstruction success rate, intraoperative blood loss, stricture length, and perioperative complications. Sensitivity analysis was employed to assess result stability, while funnel plots were utilized to evaluate publication bias in the literature.</p><p><strong>Result: </strong>A total of 16 single-arm studies were included in the analysis. The combined reconstruction success rates for the LMGU group and BMGU group were 99% (95% CI 95%-100%) and 95% (95% CI 91%-98%) respectively. The mean operation time for the LMGU group was 208.62 minutes (95% CI 181.56-235.68) and for the BMGU group was 190.65 minutes (95% CI 164.38-216.93). Intraoperative blood loss volumes for the LMGU group and BMGU group were 62.33ml (95% CI 43.15-81.51) and 113.44ml (95% CI 77.64-146.23) respectively. Stenosis lengths in the LMGU group and BMGU group were 3.98cm (95% CI 3.27-4.69) and 4.12cm (95% CI 3.24-5) respectively, with a maximum stenosis length repaired of 8cm in both groups. The incidence of postoperative complications was 25% (95% CI 15%-36%) in the BMGU group and 18% (95% CI 11%-26%) in the LMGU group.</p><p><strong>Conclusion: </strong>LMGU (lingual mucosa graft ureteroplasty) and BMGU (buccal mucosa graft ureteroplasty) are both effective and safe surgical methods for the treatment of long-segment ureteral stenosis. They have shown high effectiveness in treating mid- and upper-segment ureteral stenosis≤8cm.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-22"},"PeriodicalIF":1.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Separated Transfixing Uretero-Enteral Anastomosis Method in Robot-Assisted Radical Cystectomy with Ileal Conduit: Early Induction Experience.","authors":"Yasukazu Nakanishi, Ryo Andy Ogasawara, Naoki Imasato, Minoru Inoue, Kohei Hirose, Ken Sekiya, Madoka Kataoka, Shugo Yajima, Hitoshi Masuda","doi":"10.1159/000545124","DOIUrl":"10.1159/000545124","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to evaluate the initial outcomes of a novel transfixing uretero-enteral anastomosis technique in robot-assisted radical cystectomy (RARC) with ileal conduit in an intracorporeal urinary diversion (ICUD), focusing on its potential to reducing the incidence of uretero-enteric anastomotic stricture.</p><p><strong>Methods: </strong>The study subjects were 11 patients who underwent RARC and ileal conduit created as an ICUD at a single cancer center between 2022 and 2024. The technique involved opening the ventral side of the oral end of the separated ileum approximately 5 cm apart. Two small holes were made 2 cm from the oral end on the dorsal side, through which the ureter passed to the luminal side. The distal end of the ureter was spatulated, and four knotted sutures were placed at the base using 4-0 absorbable sutures. The distal end of the ureter was anchored using two knotted sutures, and the liberated portion was closed using 3-0 absorbable suture in a running fashion.</p><p><strong>Results: </strong>The median total operation time was 418 min (range: 269-467 min), with a median console time of 93 min (range: 80-129 min) for urinary diversion. Two patients required temporary stent reinsertion because of hydronephrosis; however, no pyelonephritis occurred. Two patients (18.2%) had complications of Clavien-Dindo classification 3 or higher, both of which only required temporary stent reinsertion. Postoperative renal function was preserved in all the patients.</p><p><strong>Conclusions: </strong>In our initial experience, the transfixing uretero-enteral anastomosis technique was successful in stabilizing anastomoses in ICUD.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of 10-20 mm Renal Stones: SWL vs. Flexible Ureteroscopy.","authors":"Erhan Erdoğan, Ahmet Fatih Kanberoğlu, Alper Aşık, Göksu Sarıca, Kemal Sarica","doi":"10.1159/000545108","DOIUrl":"https://doi.org/10.1159/000545108","url":null,"abstract":"<p><strong>Introduction: </strong>To compare the efficacy and safety of Shock Wave Lithotripsy (SWL) and flexible Ureteroscopy (fURS) in treating unilateral moderate-sized (10-20 mm) kidney stones, with a focus on changes in quality of life (QoL).</p><p><strong>Methods: </strong>This study included 112 patients with unilateral radiopaque kidney stones. Patients were divided into two groups: SWL (n=64) and fURS (n=48). Treatment outcomes, including QoL changes, were evaluated comparatively between the groups.</p><p><strong>Results: </strong>Both groups were similar in terms of age, gender, stone size, and density. Short-term (4-week) stone-free rates were higher in the fURS group (79.17% vs. 51.56%, p=0.003). However, at 3 months, there was no significant difference in stone-free rates (89.8% vs. 85.2%, p=0.098). Pain levels, assessed using the Visual Analog Scale (VAS), showed no difference 1 hour post-procedure (p=0.338), but SWL had lower pain scores at 4 hours (p=0.002). QoL, assessed with the SF-36 questionnaire, indicated an advantage for SWL in energy/fatigue parameters (p=0.017), with no significant differences in other domains. SWL was particularly beneficial for energy levels and emotional well-being.</p><p><strong>Conclusions: </strong>SWL's non-invasive nature, reduced pain levels, and advantages in specific QoL parameters make it an effective treatment option for medium-sized kidney stones. While fURS offers better short-term stone clearance, SWL demonstrates comparable long-term efficacy with added QoL benefits.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-14"},"PeriodicalIF":1.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Procalcitonin, Systemic Inflammatory Index, and C-Reactive Protein and Skin Reconstruction in Fournier's Gangrene Patients: A Retrospective Single-Center Study.","authors":"Salih Bürlukkara, Özer Baran","doi":"10.1159/000545013","DOIUrl":"10.1159/000545013","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to examine the relationship between skin reconstruction and systemic inflammatory index (SII), procalcitonin in Fournier's gangrene.</p><p><strong>Methods: </strong>Forty-seven male patients who underwent debridement and were diagnosed with Fournier's gangrene were included in this retrospective study. The patient groups were divided into two groups. Group 1 included 26 patients who required primary skin closure, and Group 2 included 21 patients who required skin grafts and flaps. Data regarding initial symptoms, physical examination findings, vital signs, and laboratory tests were collected through archive scanning. Patients with available data for the Fournier's gangrene severity index (FGSI), Uludağ's Fournier's gangrene severity index (UFGSI), procalcitonin, C-reactive protein (CRP), and SII calculations were included in the study.</p><p><strong>Results: </strong>A significant difference in vital signs was found between the groups. Fever, pulse and respiratory rate were significantly greater in Group 2 than in Group 1 (p = 0.747). There was no significant difference in body mass index (BMI) or duration of hospitalization (p = 0.983). The average procalcitonin level of the patients measured preoperatively was 1.01 in Group 1 and 2.30 in Group 2. In Group 1, the average CRP level was 111.90, the SII was 3,460.00; in Group 2, the CRP level was 165.00, the SII was 6,544.00, and this difference between the two groups was significant (p = 0.011-0.018).</p><p><strong>Conclusion: </strong>CRP, procalcitonin, and SII rates can be measured simply, easily applied, and can provide insight into predicting skin reconstruction.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of radical cystectomy with orthotopic neobladder reconstruction in patients developing bladder cancer after prior radical prostatectomy, radiation therapy or BPH surgery.","authors":"Nikolaos Pyrgidis, Yannic Volz, Sarah Takayama Fouladgar, Benedikt Ebner, Philipp Weinhold, Julian Marcon, Michael Chaloupka, Christian G Stief, Gerald Schulz, Patrick Keller","doi":"10.1159/000545103","DOIUrl":"https://doi.org/10.1159/000545103","url":null,"abstract":"<p><strong>Introduction: </strong>Current evidence suggests that prior prostatic interventions, such as prostatectomy, radiation, or transurethral surgery may increase the risk of incontinence in patients undergoing radical cystectomy (RC) with ileal orthotopic neobladder reconstruction. We aimed to evaluate the short- and long-term complications, functional outcomes of neobladder reconstruction in patients undergoing RC after prior prostatic procedures.</p><p><strong>Methods: </strong>We analyzed patients who underwent RC after prior prostatic intervention in our department from 2013-2022. A comparison was made between patients receiving neobladder reconstruction (ONB) versus ileal conduit, including propensity-score-matching for age and preoperative continence.</p><p><strong>Results: </strong>We included 79 patients who underwent RC for bladder cancer after prior prostatic intervention. Of them, 43 (54%) patients had previously undergone BPH surgery, 29 (37%) radical prostatectomy and 7 (9%) prostate radiation therapy. An ileal conduit was performed in 62 (78%) cases. Patients presented similar baseline characteristics, perioperative complications, and quality of life after RC. Accordingly, after propensity-score-matching patients with ONB after prior prostatic intervention and patients who received ONB without prior prostatic intervention did not differ significantly in their baseline characteristics, perioperative complications and quality of life. 24% of patients without prior intervention reported incontinence, compared to 53% with prior prostatic intervention.</p><p><strong>Conclusion: </strong>Neobladder reconstruction remains to be a feasible option in patients undergoing RC after prior prostatic intervention.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-17"},"PeriodicalIF":1.5,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SIRT7 Expression Predicts Poor Prognosis in Upper Tract Urothelial Carcinoma Undergoing Postoperative Platinum-Based Adjuvant Chemotherapy.","authors":"Yudong Cao, Jinchao Ma, Shuo Wang, Xiao Yang, Mengping Long, Yongpeng Ji, Ziyi Yu, Ruijian You, Chen Lin, Yong Yang, Peng Du","doi":"10.1159/000544698","DOIUrl":"10.1159/000544698","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to evaluate the expression of SIRT7 in upper tract urothelial carcinoma (UTUC) as well as the predictive value for prognosis in patients undergoing radical nephroureterectomy followed platinum-based adjuvant chemotherapy.</p><p><strong>Methods: </strong>Pathological samples of 146 UTUC with clinical stage T2 and above undergoing radical nephrectomy (RNU) were collected. All patients received adjuvant cisplatin-based chemotherapy and 40 UTUC patients received second-line immunotherapy after disease progression. The relationship between the expression level of SIRT7 by immunohistochemistry and clinicopathological characteristics, disease-free survival (DFS), overall survival (OS), and OS after progression (POS) was analyzed.</p><p><strong>Results: </strong>Over a mean follow-up 47 months, 61 (41.8%) patients experienced recurrence and 42 (28.8%) patients died due to UTUC. The results revealed that 70.2% of UTUC tissue samples exhibited high expression levels of SIRT7. High expression of SIRT7 is associated with lymph node metastasis (p < 0.001), lymphovascular invasion (p = 0.001), and histological differentiation (p = 0.025). In addition, UTUC patients with elevated SIRT7 expression experienced significantly shorter DFS (hazard ratio [HR] 3.760, 95% CI: 1.884-7.504, p < 0.001 and OS (HR 2.706, 95% CI: 1.235-5.929, p = 0.013). Multivariate analyses demonstrated that SIRT7 served as a significant predictor for DFS (HR 2.337, 95% CI: 1.117-4.890, p = 0.024) in UTUC patients. Furthermore, we found SIRT7 high expression is associated with prolonged POS in patients progressed after adjuvant cisplatin-based chemotherapy and received second-line immunotherapy.</p><p><strong>Conclusion: </strong>SIRT7 is an independent prognostic marker of poor DFS in locally advanced UTUC patients after RNU. Moreover, these data suggest that SIRT7 could potentially serve as a target for assessing the efficacy of chemotherapy and immunotherapy in UTUC.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stage Migration in Urological Cancers in Germany during the COVID-19 Pandemic: Fact or Fiction?","authors":"Henning Bahlburg, Patricia Rausch, Matteo Silberg, Karl Heinrich Tully, Sebastian Berg, Joachim Noldus, Marius Cristian Butea-Bocu, Burkhard Beyer, Guido Müller","doi":"10.1159/000544745","DOIUrl":"10.1159/000544745","url":null,"abstract":"<p><strong>Introduction: </strong>The COVID-19 pandemic interrupted many aspects of health care, including cancer treatment. This study aims to assess the potential impact of the COVID-19 pandemic on tumor stage migration in the three most common urological malignancies.</p><p><strong>Methods: </strong>Patient and tumor characteristics of patients undergoing inpatient rehabilitation (IR) in one dedicated IR center in 2019 (pre-pandemic) and 2021 (mid-pandemic) were retrospectively evaluated. The study focused on patients after radical prostatectomy (RP) for prostate cancer (PCa), radical cystectomy (RC) for bladder cancer (BCa), or (partial) nephrectomy for kidney cancer (KC).</p><p><strong>Results: </strong>Overall, 9,039 patients (6,898 (76.3%) after RP, 1,427 (15.8%) after RC, 714 (7.9%) after (partial) nephrectomy) were enrolled. A significant decrease of PCa patients suffering from Gleason sum score ≥8 (17.6% vs. 20.5%, p = 0.005) and lymph node metastases (10.9% vs. 13.0%; p = 0.012) was observed. In BCa and KC patients, tumor stage distribution and abundance of lymph node metastases remained stable, while significantly more BCa patients received neoadjuvant chemotherapy (10.4% vs. 20.2%, p = 0.001). Overall, a significant increase in robot-assisted surgery across all investigated malignancies was detected.</p><p><strong>Conclusions: </strong>No stage migration could be detected across the three most common urological malignancies during the COVID-19 pandemic. Therapeutic standards remained high, while oncological outcomes remained relatively unchanged.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}