Urologia Internationalis最新文献

{"title":"Glanular Ischemia following Glans Penis Augmentation: A Rare Case Report.","authors":"Kaan Karamık, Ali Yıldız, Ömer Koraş, Murat Arslan","doi":"10.1159/000547421","DOIUrl":"10.1159/000547421","url":null,"abstract":"<p><strong>Introduction: </strong>Premature ejaculation is a common problem in men and filler injection into the glans penis has become a prevalent practice in treatment. Since the glans penis augmentation is an invasive treatment method, it also carries the risk of complications. Herein, we aimed to present a case of glans penis ischemia due to hyaluronic acid filler injection.</p><p><strong>Case presentation: </strong>The patient was a 29-year-old male with premature ejaculation. The physical examination was normal, and sensory testing with a biothesiometer revealed vibration perception threshold values of 5.3V for the glans, 4.1V for the frenulum, and 3.9V for the penile shaft. Under local anesthesia, hyaluronic acid filler was applied with the multiple puncture technique, 2 mL in total, 0.2 mL per injection. One day after the procedure, the patient referred with complaints of discoloration of the glans penis. The physical examination revealed blackening at the distal tip of the glans with a visible demarcation line. Hyaluronidase was applied for the treatment of glanular glans penis ischemia secondary to hyaluronic acid filler injection. A significant improvement in the glans penis color was observed after hyaluronidase injection. The patient was prescribed 100 mg of aspirin, a warm saline dressing, and a nitroglycerin-containing cream and was discharged for daily follow-up.</p><p><strong>Conclusion: </strong>Although vascular complications are rare after hyaluronic acid filling into the glans penis, early diagnosis and treatment are crucial. Patients should be informed about possible adverse events. The main treatment method for vascular complications is urgent hyaluronidase injection. In addition, prevention of clot propagation with oral aspirin and vasodilatation treatments should be applied. In the glans penis ischemia after hyaluronic acid injection, early diagnosis and immediate hyaluronidase administration can reverse ischemia without necrosis or surgical intervention.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-5"},"PeriodicalIF":1.3,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Urinary Microbiota in Chronic Cystitis Based on Midstream Urine Sample.","authors":"Margarita Boldyreva, Maria Petrunicheva, Anastasia Ivanova, Andrey Morozov, Svetlana Koroleva, Zoya Moskvina, Ksenia Rossolovskaya, Leonid Spivak","doi":"10.1159/000547112","DOIUrl":"10.1159/000547112","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to compare the urinary microbiota of healthy women, women with a predisposition to UTIs, and patients with chronic recurrent cystitis using real-time PCR, as well as identify diagnostic markers for urinary diseases.</p><p><strong>Methods: </strong>The study enrolled 3 groups of patients: a healthy control group, patients with chronic recurrent cystitis, and patients with a risk of developing UTIs. Urine samples were analyzed by multiplex real-time PCR reagent kits Femoflor®16 and BacScreen OM.</p><p><strong>Results: </strong>Chronic recurrent cystitis is associated with an increase in total bacterial mass (TBM), genomic DNA, and relative predominance of facultative anaerobic microorganisms. The most prevalent bacterial species found in chronic cystitis was Escherichia coli in conjunction with other Enterobacteriaceae, most commonly Serratia marcescens. An increased amount of genomic DNA and both facultative and obligate anaerobic microorganisms was observed in patients with a risk of developing UTIs. A relative decrease in Lactobacillus spp. was noted in both groups, with the chronic cystitis group showing a more pronounced reduction.</p><p><strong>Conclusion: </strong>In summary, the levels of genomic DNA, TBM, and relative values of Lactobacillus spp. can be used as molecular diagnostic markers for chronic cystitis and a variety of other conditions, including micronephrolithiasis and bacterial vaginosis.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-6"},"PeriodicalIF":1.3,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexually Transmitted Infections in Prostate Cancer: A Prospective Multicenter Analysis.","authors":"Teresa Pina-Vaz, Alberto Costa Silva, Gabriel Costa, Micael Gonçalves, Angela Fernandes, Frederico Carmo Reis, Pedro Nobre, Carmen Lisboa, Acacio Rodrigues, João Alturas-Silva, Carlos Martins-Silva","doi":"10.1159/000545208","DOIUrl":"10.1159/000545208","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic inflammation and infections have been implicated in prostate cancer (PCa) pathogenesis. The association between sexually transmitted infections (STIs) and PCa remains inconclusive. The objective was to evaluate the presence of STI-related pathogens in patients with PCa compared to a control group.</p><p><strong>Methods: </strong>A prospective multicenter study involving 239 male patients with a clinical suspicion of PCa was conducted. Among the participants, 176 had histologically confirmed PCa, while 63 served as controls with benign histology. Urine, glans swabs, and prostate biopsy specimens were collected from each participant and analyzed using polymerase chain reaction (PCR) to detect a broad panel of STI-causing pathogens, including Candida spp., Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, Trichomonas vaginalis, herpes simplex virus types 1 and 2, and human papillomavirus.</p><p><strong>Results: </strong>A total of 717 samples were processed. The detection frequency of STI-related pathogens was relatively low across all sample types. M. genitalium was the most frequently detected pathogen, particularly in prostate biopsy samples. No statistically significant association was found between the presence of these pathogens and the incidence of PCa. N. gonorrhoeae and C. spp. were not detected in any of the samples.</p><p><strong>Conclusion: </strong>This study did not find a statistically significant association between the presence of STIs and PCa. The low prevalence of STI pathogens despite the use of highly sensitive PCR methods suggests that these infections may play a limited role in prostate carcinogenesis. Future research should consider focusing on the role of the urinary and prostatic microbiome in chronic prostatic inflammation.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of a Novel &lt;5 mm Ureteral Dilation Balloon Catheter in Holmium Laser Surgery for Ureteral Calculi with Physiological Narrowing: A Randomized Controlled Trial.","authors":"He Zhang, Lin Zhang, Yuhan Hou, Xiangmin Zhang, Yiyang Liu, Zhihui Dong, Jian Chu, Jianwei Cao","doi":"10.1159/000546458","DOIUrl":"10.1159/000546458","url":null,"abstract":"<p><strong>Introduction: </strong>The \"difficult ureter\" specifically denotes narrow and tortuous ureters typically requiring two-stage surgery. We first proposed combining a visible ureteral dilation balloon catheter with a holmium laser to treat ureteral calculi in patients with ureteral stenosis.</p><p><strong>Methods: </strong>A prospective, multicenter, randomized, open-label, and controlled study enrolled 60 ureteral calculi patients with ureteral stricture from July 2021 to July 2023. Patients were randomly assigned to either first-stage ureteroscopic lithotripsy with direct visualization balloon dilation (DVBD + FUS) or dilation using a scope and inner core (DUS + S). The primary outcome was the success of sheath placement at first-stage surgery, assessed by the secondary operation rate. Secondary outcomes included stone clearance rates, postoperative serum creatinine increase, decreased hemoglobin, total hospital stay, operation time, ureteral stent removal time, ureteral injury, and total surgery costs.</p><p><strong>Results: </strong>Sixty patients aged 24-68 were enrolled, with stone diameters ranging from 0.6 to 2 cm (average 1.4 cm). After first-stage surgeries, 17 (56.67%) in the DUS + S group and 4 (13.3%) in the DVBD + FUS group required secondary surgery (p < 0.001). The DVBD + FUS group had a significantly shorter hospital stay by 3.2 days (6.60 vs. 3.4 days, p < 0.001) and a shorter operation time by 11 min (p = 0.010). After 3 months, ureteral stent removal times were similar (28.1 ± 8.5 vs. 26.1 ± 6.3 days). Total costs were CNY 7,800 lower in the DVBD + FUS group (p < 0.001). Intraoperative and postoperative complications were comparable. Six-month follow-ups showed no hydronephrosis in either group.</p><p><strong>Conclusion: </strong>Our study firstly indicated that DVBD + FUS could be an efficacious and safe strategy for treating ureteral calculi in patients with ureteral stricture. Moreover, DVBD + FUS treatment largely decreased total hospital stays, total operation time, and costs.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Propensity-Score-Based Comparative Analysis of Transperitoneal and Retroperitoneal Approaches in Open and Minimally Invasive Renal Surgery: Impact on Operative Outcomes.","authors":"Marcel Schwinger, Lena Knaier, Charis Kalogirou, Robert Woidich, Oliver Hahn, Hubert Kübler, Vincent Scheper","doi":"10.1159/000546230","DOIUrl":"10.1159/000546230","url":null,"abstract":"<p><strong>Introduction: </strong>Renal cancer is among the ten most common cancers in western societies, with renal cell carcinoma (RCC) accounting for 95% of malignant renal neoplasms. Recent advances in surgical techniques and approaches have expanded treatment options, necessitating an evaluation of optimal approaches.</p><p><strong>Methods: </strong>A retrospective, propensity-matched cohort with 814 patients (1999-2021) was conducted comparing open and minimally invasive (laparoscopic and robotic-assisted) nephrectomy and partial nephrectomy techniques, focusing on operative time, blood loss, hospital stay, complications, and perioperative complications.</p><p><strong>Results: </strong>The retroperitoneal (RP) approach demonstrated shorter operation times, reduced blood loss, and quicker recovery compared to the transperitoneal (TP) approach. Minimal invasive techniques, whether laparoscopic or robotic, had shorter hospital stays, fewer complications, and better postoperative renal function. The RP approach showed advantages in operative efficiency and reduced postoperative morbidity.</p><p><strong>Conclusion: </strong>The findings support that the RP approach is at least as effective as, or superior to, the TP approach in terms of perioperative outcomes. Minimally invasive approaches, including robotic-assisted and laparoscopic techniques, are associated with improved recovery and fewer complications, highlighting their advantages in the surgical treatment of renal tumors. Further studies are needed to assess long-term oncologic and functional outcomes. These findings underline the importance of tailored surgical planning to optimize patient outcomes.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integral Theory Paradigm: Common Pelvic Ligament Pathogenesis Guides Management for Urology, Gynecology, Coloproctology.","authors":"Peter Petros, Bernhard Liedl, Ahmet Akin Sivaslioglu, Klaus Goeschen, Hiromi Inoue, Yuki Sekiguchi, Burghard Abendstein, Dmitry Shkarupa, Nikita Kubin","doi":"10.1159/000545665","DOIUrl":"10.1159/000545665","url":null,"abstract":"<p><strong>Background: </strong>This work had its origins in the 1990s, when women having collagen-creating midurethral slings for stress urinary incontinence (SUI) and uterosacral slings for uterine prolapse began reporting cure or improvement in co-occurring fecal incontinence, obstructive defecation, and chronic pelvic pain.</p><p><strong>Summary: </strong>We briefly describe anatomical etiopathogenesis to explain how the same collagen-creating ligament repair system using a common ligament-based diagnostic system, can treat pelvic symptoms from 3 disciplines: Urology, Gynecology, Coloproctology. Collagen-induced laxity in ligaments and vagina diminishes contractile forces required by pelvic muscles to close urethra and anus for continence, open them for evacuation, and stretch the bladder base and rectum like a trampoline to prevent stretch receptors prematurely activating micturition and defecation reflexes. These are perceived cortically as bladder or fecal \"urge to go.\" The pictorial algorithm summarizes common ligament pathogeneses for prolapse/bladder/bowel/pain dysfunctions which can be confirmed by mechanical support of PUL for relief of urine loss on coughing, and uterosacral ligaments (USL) for relief of urge and chronic pelvic pain. The same minimally invasive ligament repairs used for SUI, prolapse, pain/bladder dysfunctions were demonstrated by X-ray defecography controlled studies to cure fecal incontinence, obstructive defecation, anterior rectal wall intussusception and descending perineal syndrome (as shown in 16 case managements in 3 disciplines; video: <ext-link ext-link-type=\"uri\" xlink:href=\"https://youtu.be/a6jJQXDx71U?si=MLdo3Yq9kAZ82RVb\" xmlns:xlink=\"http://www.w3.org/1999/xlink\">https://youtu.be/a6jJQXDx71U?si=MLdo3Yq9kAZ82RVb</ext-link>).</p><p><strong>Key messages: </strong>Symptom relief can be achieved using standard operations which repair PUL or USL even with minimal prolapse. Whether the surgery is done laparoscopically or vaginally is of little consequence, as the same structure is repaired.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-13"},"PeriodicalIF":1.5,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usage of the Internet and Digital Health among Urological Patients: Findings from a Cross-Sectional Study.","authors":"Rashid Al Sliman, Timur H Kuru, Julian P Struck, Anna L Heinrichs, Katharina Arndt, Johannes Salem, Hendrik Borgmann","doi":"10.1159/000544873","DOIUrl":"10.1159/000544873","url":null,"abstract":"<p><strong>Introduction: </strong>The rising prevalence of Internet usage and smartphone applications among urology patients underscores the critical role of digital health literacy. This study investigates the acceptability of digital health technologies among urology patients and identifies factors influencing their acceptance.</p><p><strong>Materials and methods: </strong>A cross-sectional, anonymous survey consisting of 12 questions was developed based on literature research. It was conducted online using SurveyMonkey and targeted patients in the CUROS network in Germany. The data were analyzed descriptively using SPSS.</p><p><strong>Results: </strong>Of 1,039 participants, 99.1% reported using the Internet, with 84.4% using it several times daily. YouTube emerged as the most popular social media platform. While 90.2% searched for health information online, trust in online resources was low (mean score 4.63). Only 35.2% used medical apps, but 62.8% expressed willingness to use them if prescribed. Furthermore, 74.2% supported the use of electronic patient records, although concerns regarding privacy were noted.</p><p><strong>Conclusions: </strong>Urology patients demonstrate a high engagement with digital resources but express concerns about the reliability of online health information. Enhancing education on digital health tools and fostering trust in these resources is essential for improving patient outcomes and encouraging the integration of digital health in urological care.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Geriatric Nutritional Risk Index as a Predictor of Outcomes in Urological Cancers: A Systematic Review and Meta-Analysis.","authors":"Yuefen Chen, Mei Wen, Zhe Yu, Fengjiao Xu","doi":"10.1159/000544793","DOIUrl":"10.1159/000544793","url":null,"abstract":"<p><strong>Introduction: </strong>The geriatric nutritional risk index (GNRI) is being used to predict outcomes of several malignancies. However, its utility for urinary tract cancer has not been systematically analyzed. We present the first meta-analysis examining the association between GNRI and the prognosis of urological cancers.</p><p><strong>Methods: </strong>This PROSPERO registered review searched Embase, PubMed, Web of Science, and Scopus up to 25 November 2024 for studies examining the relationship between GNRI and overall survival (OS), cancer-specific survival (CSS), and progression-free survival (PFS) after urological cancers.</p><p><strong>Results: </strong>A total of 20 studies were eligible. Three studies were on bladder cancer, four on prostate cancer, seven on renal cell carcinoma (RCC), and six on urothelial cancers. Meta-analysis showed that low GNRI was a statistically significant predictor of poor OS in prostate cancer (OR: 3.02; 95% CI: 1.61, 5.67). Pooled analysis showed that low GNRI was associated with poor OS (OR: 2.17; 95% CI: 1.46, 3.22) and CSS (OR: 2.60; 95% CI: 1.57, 4.30) in RCC but not PFS (OR: 1.50; 95% CI: 1.00, 2.24). Pooled analysis also found that low GNRI was a predictor of worse OS (OR: 2.24; 95% CI: 1.52, 3.29) and CSS (OR: 3.07; 95% CI: 1.38, 6.86) in urothelial carcinoma. A narrative review on bladder cancer and GNRI showed mixed results.</p><p><strong>Conclusion: </strong>GNRI may have a role in predicting outcomes of urological malignancies. Low GNRI was independently associated with worse OS after prostate, renal cell, and urothelial carcinoma. Further, it also predicted CSS after RCC and urothelial carcinoma.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-14"},"PeriodicalIF":1.5,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraindividual Perception of Open versus Robot-Assisted Partial Nephrectomy (PERCEPTION Trial): An Important Complementing Perspective to Randomized Controlled Trials.","authors":"Philipp Reimold, Luisa Bourgeois, Lia Klefenz, Marius Christian Butea-Bocu, Anna Lena Jacobi, Luka Flegar, Christer Groeben, Johannes Huber","doi":"10.1159/000545583","DOIUrl":"10.1159/000545583","url":null,"abstract":"<p><strong>Introduction: </strong>Randomized controlled trials comparing patients' experience with open (OPN) vs. robot-assisted (RAPN) partial nephrectomy showed no clear advantages for RAPN. This contradicts our clinical impression, so we analyzed a cohort that underwent both approaches for bilateral renal tumors. The aim of our study was to compare their intraindividual perceptions of OPN and RAPN.</p><p><strong>Methods: </strong>Scar assessment and evaluation of patient-reported outcome measures were conducted. The questionnaires were retrospectively answered for postoperative day 5 after OPN and RAPN and, as a reference, for the date of presentation.</p><p><strong>Results: </strong>Results revealed longer hospitalization and ischemia times in patients with OPN, while ratings for physical condition and quality of life were better in the RAPN group. Stress, depression, and anxiety in cancer patients scored higher in the OPN group. Scar assessment revealed less patient-reported satisfaction after OPN. Patients favored RAPN when comparing both approaches directly and were more likely to recommend RAPN to a friend.</p><p><strong>Conclusion: </strong>This is the first study on the intraindividual perception of OPN vs. RAPN, revealing a comparative judgement clearly in favor of RAPN. Based on our findings, we designed the APPROACH trial to compare OPN and RAPN in a representative population under the conditions of routine care.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12091961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bladder Stone Composition in Jiangsu Region of China: Results from 421 Stone Analyses.","authors":"Chen Zhu, Long Ma, Xuehua Chen, Yue Zhou, Yunfei Wei, Ping Zhou, Ninghong Wang, Jian Su, Lin Yuan, Yan Xu","doi":"10.1159/000542255","DOIUrl":"10.1159/000542255","url":null,"abstract":"<p><strong>Introduction: </strong>Accurate analysis of bladder stone composition is essential for appropriate treatment planning and recurrence prevention. The aim of this study was to evaluate the characteristics of bladder stone components in our center.</p><p><strong>Methods: </strong>A retrospective analysis on the composition of bladder stones collected in our center from January 2014 to March 2023 was conducted in the present work. Age, sex, and laboratory examination of all patients were collected. Infrared spectroscopy was conducted for stone analysis.</p><p><strong>Results: </strong>The most common stone component was calcium oxalate (43.0%), followed by uric acid (UA) stone (35.4%), calcium phosphate (12.10%), infection stone (9.0%), and cystine (0.5%). The highest stone prevalence appeared in patients aged over 60 years and increased progressively with age. Furthermore, patients with UA stones were more likely to have a lower urinary pH. Additionally, patients with infection stones showed higher incidence of urinary tract infections than those with other types of stones. Patients with UA stones had higher average serum UA and creatinine levels. UA stones are more likely to form multiple stones compared to stones of other composition. The volume of infectious stones is larger compared to stones of other compositions.</p><p><strong>Conclusion: </strong>This study highlights the importance of gaining a deeper understanding of bladder stone composition, as it can lead to more effective evaluation, treatment, and prevention of stone disease.</p>","PeriodicalId":23414,"journal":{"name":"Urologia Internationalis","volume":" ","pages":"1-6"},"PeriodicalIF":1.5,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}