Turkish Journal of Chemistry最新文献_第8页

Homoprotocatechuate dioxygenase active site: Imitating the secondary sphere base via computational design 同源儿茶酸双加氧酶活性位点:通过计算设计模拟次生球基

4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3598

MUHAMMED BUYUKTEMIZ, YAVUZ DEDE

引用次数: 0

Water-soluble phthalocyanine photosensitizers for photodynamic therapy 光动力治疗用水溶性酞菁光敏剂

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Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3583

İPEK ÖMEROĞLU, MAHMUT DURMUŞ

{"title":"Water-soluble phthalocyanine photosensitizers for photodynamic therapy","authors":"İPEK ÖMEROĞLU, MAHMUT DURMUŞ","doi":"10.55730/1300-0527.3583","DOIUrl":"https://doi.org/10.55730/1300-0527.3583","url":null,"abstract":"Photodynamic therapy (PDT) is based on a photochemical reaction that is started when a photosensitizing process is activated by the light and results in the death of tumor cells. Solubility is crucial in PDT applications to investigate the physical and chemical characteristics of phthalocyanines, but, unfortunately, most phthalocyanines show limited solubility especially in water. To increase the solubility of phthalocyanines in polar solvents and water, ionic groups such as -SO3 - , -NR3 +, -COO- , and nonionic groups such as poly-oxy chains are frequently added to the peripheral or nonperipheral positions of the phthalocyanine framework. Since water-solubility and NIR-absorbing properties are essential for efficient PDT activation, studies have been focused on the synthesis of these types of phthalocyanine derivatives. This review focuses on the photophysical, photochemical, and some in vitro or in vivo studies of the recently published ionic and nonionic phthalocyanine-mediated photosensitizers carried out in the last five years. This review will have positive contributions to future studies on phthalocyanine chemistry and their PDT applications as well as photochemistry","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"49 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135930906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Arsenic speciation by using emerging sample preparation techniques: a review 新型样品制备技术对砷形态形成的影响

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Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3590

MUHAMMAD SAQAF JAGIRANI, MUSTAFA SOYLAK

{"title":"Arsenic speciation by using emerging sample preparation techniques: a review","authors":"MUHAMMAD SAQAF JAGIRANI, MUSTAFA SOYLAK","doi":"10.55730/1300-0527.3590","DOIUrl":"https://doi.org/10.55730/1300-0527.3590","url":null,"abstract":"Arsenic is a hazardous element that causes environmental pollution. Due to its toxicological effects, it is crucial to quantify and minimize the hazardous impact on the ecology. Despite the significant advances in analytical techniques, sample preparation is still crucial for determining target analytes in complex matrices. Several factors affect the direct analysis, such as trace-level analysis, advanced regulatory requirements, complexity of sample matrices, and incompatible with analytical instrumentation. Along with the development in the sample preparation process, microextraction methods play an essential role in the sample preparation process. Microextraction techniques (METs) are the newest green approach that replaces traditional sample preparation and preconcentration methods. METs have minimized the limitation of conventional sample preparation methods while keeping all their benefits. METs improve extraction efficacy, are fast, automated, use less amount of solvents, and are suitable for the environment. Microextraction techniques with less solvent consumption, such as solid phase microextraction (SPME) solvent-free methods, and liquid phase microextraction (LPME), are widely used in modern analytical procedures. SPME development focuses on synthesizing new sorbents and applying online sample preparation, whereas LPME research investigates the utilization of new solvents.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"5 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135931731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A facile tert-butyl nitrite-assisted preparation of deamino graphitic carbon nitride (DA-gCN) as a photocatalyst for the C-H arylation of heteroarenes using anilines as radical source 以苯胺为自由基源，亚硝酸盐叔丁基辅助制备脱氨基石墨氮化碳(DA-gCN)作为杂芳烃C-H基化的光催化剂

4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3605

PALANI NATARAJAN, BEGÜMHAN KARAPINAR KOÇ, ÖNDER METİN

{"title":"A facile tert-butyl nitrite-assisted preparation of deamino graphitic carbon nitride (DA-gCN) as a photocatalyst for the C-H arylation of heteroarenes using anilines as radical source","authors":"PALANI NATARAJAN, BEGÜMHAN KARAPINAR KOÇ, ÖNDER METİN","doi":"10.55730/1300-0527.3605","DOIUrl":"https://doi.org/10.55730/1300-0527.3605","url":null,"abstract":"In pristine graphitic carbon nitride (g-CN), amino groups often function as structural defects that trap photogenerated charges, resulting in low photocatalytic activity as well as reaction with nitrite, aldehyde, etc., ensuing in poor product yield. Without significantly altering the optical characteristics, the removal of amino groups is necessary to increase the photocatalytic activity and structural stability of pristine g-CN. The deamino graphitic carbon nitride (DA-gCN-5) was prepared by tert-butyl nitrite (TBN)- treatment, characterized and used as a photocatalyst for the radical C-H arylation of heteroarenes using anilines as radical source. Indeed, the photophysical characteristics of DA-gCN-5 and those of pristine g-CN are very comparable, except that DA-gCN-5 has a fewer residual amino groups, higher crystallinity, and compressed structure with a different morphology. Moreover, DA-gCN-5- catalyzed C-H arylation reaction offers greater product yield in a shorter reaction time compared to that of pristine g-CN in the coupling between heteroarenes and the in situ generated aryl diazonium salts from anilines under visible light irradiation. The amino groups in pristine g-CN absorbed the TBN that was added to convert aniline into the appropriate diazonium ions during the reaction. As a result, deamino graphitic carbon nitride produced by chemical treatment has better photophysical properties and catalytic activity than pristine g-CN. Additionally, this is the first method that uses diazotization reaction for the preparation of deamino graphitic carbon nitride, as far as we are aware.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"49 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135930601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sonophotochemical and photochemical efficiency of thiazole-containing metal phthalocyanines and their gold nanoconjugates 含噻唑金属酞菁及其金纳米缀合物的声光化学和光化学效率

4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3596

NAZLI FARAJZADEH, HACER YASEMİN YENİLMEZ, GÖKNUR YAŞA ATMACA, ALİ ERDOĞMUŞ, ZEHRA BAYIR

引用次数: 0

Advanced tetra amino (ATA-100) cobalt(II) phthalocyanine-based metallo-covalent organic polymer for sensitively detecting volatile organic compounds 先进的四氨基(ATA-100)钴(II)酞菁基金属共价有机聚合物，用于灵敏检测挥发性有机化合物

4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3600

GÜNSELİ GÜNEY, GÜLAY ALTINDEMİR KAPLAN, CİHAT TAŞALTIN, İLKE GÜROL

引用次数: 0

Synthesis of new imine-/amine-bearing imidazo[1,2-a]pyrimidine derivatives and screening of their cytotoxic activity 新型含亚胺/胺咪唑[1,2-a]嘧啶衍生物的合成及其细胞毒活性筛选

4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3594

TUĞBA GÜNGÖR, HAZAL NAZLICAN ATALAY, YAKUP BERKAY YILMAZ, TUĞBA TÜMER, MEHMET AY

{"title":"Synthesis of new imine-/amine-bearing imidazo[1,2-a]pyrimidine derivatives and screening of their cytotoxic activity","authors":"TUĞBA GÜNGÖR, HAZAL NAZLICAN ATALAY, YAKUP BERKAY YILMAZ, TUĞBA TÜMER, MEHMET AY","doi":"10.55730/1300-0527.3594","DOIUrl":"https://doi.org/10.55730/1300-0527.3594","url":null,"abstract":"Imidazo[1,2-a]pyrimidine derivatives bearing imine groups (3a-e) were successfully synthesized in moderate to good yields using microwave-assisted heating. Corresponding amine derivatives (4a-e) were also obtained by the reduction reaction of the imine derivatives (3a-e). All synthesized products were characterized by FT-IR, 1 H NMR, 13C NMR, and LC-MS spectroscopic techniques. In silico ADMET, Lipinski, and drug-likeness studies of the compounds were conducted and all were found to be suitable drug candidates. The cytotoxicity of the potential drug molecules was screened against the breast cancer cell lines MCF-7 and MDA-MB-231 and the healthy model HUVEC by the sulforhodamine B method. According to the antiproliferative studies, compounds 3d and 4d showed remarkable inhibition of MCF-7 cells with IC50 values of 43.4 and 39.0 μM and of MDA-MB-231 cells with IC50 values of 35.9 and 35.1 μM, respectively. In particular, compound 3d selectively inhibited the proliferation of MCF-7 1.6-fold and MDA-MB-231 2.0-fold relative to healthy cells. Moreover, the apoptotic mechanism studies indicated that compound 4d induced apoptosis by moderately increasing the ratio of Bax/Bcl-2 genes. Imidazo[1,2-a]pyrimidine derivative 3d, a promising cytotoxic agent, may be helpful in the discovery of new and more efficient anticancer agents for breast cancer treatment.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135930895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cibacron Blue F3GA ligand dye-based magnetic silica particles for the albumin purification Cibacron Blue F3GA配体染料基磁性二氧化硅颗粒纯化白蛋白

4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3599

NURHAK TATAR, SEMRA AKGÖNÜLLÜ, HANDAN YAVUZ ALAGÖZ, ADİL DENİZLİ

{"title":"Cibacron Blue F3GA ligand dye-based magnetic silica particles for the albumin purification","authors":"NURHAK TATAR, SEMRA AKGÖNÜLLÜ, HANDAN YAVUZ ALAGÖZ, ADİL DENİZLİ","doi":"10.55730/1300-0527.3599","DOIUrl":"https://doi.org/10.55730/1300-0527.3599","url":null,"abstract":"Dye-ligand affinity chromatography is among the increasingly popular affinity chromatography based on molecular recognition for the purification of albumin. This study focuses on the binding of Cibacron Blue F3GA ligand dye with magnetic silica particles and purification by separation. Mono-disperse silica particles with bimodal pore size distribution were employed as a high-performance adsorbent for human serum albumin (HSA) protein purification under equilibrium conditions. The synthesized ligand-dye affinity based magnetic silica particles were characterized by electron spin resonance, Fourier-transform infrared spectroscopy, scanning electron microscopy, vibrating sample magnetometer, elemental analysis, and dispersive X-ray analysis. The HSA purification performance of the proposed material in the presence of a magnetic field was relatively investigated using magnetic-based particles with similar morphologies. The maximum adsorption capacity for HSA in an artificial plasma medium was defined as 48.6 mg/g magnetic silica particle. By using the designed magnetic silica particles, 1.0 M NaCl solution was successfully utilized for obtaining quantitative desorption with HSA. However, continued HSA purification performances of magnetic-based particles were significantly lower concerning the ligand-dye magnetic silica particles. The purity of the removed albumin was about 97%. The magnetic silica particles could be utilized many times without decreasing their protein adsorption capacities remarkably.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"98 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135931727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reducible tungsten(VI) oxide-supported ruthenium(0) nanoparticles: highly active catalyst for hydrolytic dehydrogenation of ammonia borane 还原性氧化钨负载钌纳米颗粒:氨硼烷水解脱氢的高活性催化剂

4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3607

SERDAR AKBAYRAK, YALÇIN TONBUL, SAİM ÖZKAR

{"title":"Reducible tungsten(VI) oxide-supported ruthenium(0) nanoparticles: highly active catalyst for hydrolytic dehydrogenation of ammonia borane","authors":"SERDAR AKBAYRAK, YALÇIN TONBUL, SAİM ÖZKAR","doi":"10.55730/1300-0527.3607","DOIUrl":"https://doi.org/10.55730/1300-0527.3607","url":null,"abstract":"Reducible WO3 powder with a mean diameter of 100 nm is used as support to stabilize ruthenium(0) nanoparticles. Ruthenium(0) nanoparticles are obtained by NaBH4 reduction of ruthenium(III) precursor on the surface of WO3 support at room temperature. Ruthenium(0) nanoparticles are uniformly dispersed on the surface of tungsten(VI) oxide. The obtained Ru0 /WO3 nanoparticles are found to be active catalysts in hydrolytic dehydrogenation of ammonia borane. The turnover frequency (TOF) values of the Ru0 /WO3 nanocatalysts with the metal loading of 1.0%, 2.0%, and 3.0% wt. Ru are 122, 106, and 83 min-1, respectively, in releasing hydrogen gas from the hydrolysis of ammonia borane at 25.0 °C. As the Ru0 /WO3 (1.0% wt. Ru) nanocatalyst with an average particle size of 2.6 nm provides the highest activity among them, it is extensively investigated. Although the Ru0 /WO3 (1.0% wt. Ru) nanocatalyst is not magnetically separable, it has extremely high reusability in the hydrolysis reaction as it preserves 100% of initial catalytic activity even after the 5th run of hydrolysis. The high activity and reusability of Ru0 /WO3 (1.0% wt. Ru) nanocatalyst are attributed to the favorable metal-support interaction between the ruthenium(0) nanoparticles and the reducible tungsten(VI) oxide. The high catalytic activity and high stability of Ru0 /WO3 nanoparticles increase the catalytic efficiency of precious ruthenium in hydrolytic dehydrogenation of ammonia borane.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"2020 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135931730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluid-based wearable sensors: a turning point in personalized healthcare 基于流体的可穿戴传感器:个性化医疗保健的转折点

4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI: 10.55730/1300-0527.3588

BERFİN VURAL, İNCİ ULUDAĞ, BAHAR İNCE, CANAN ÖZYURT, FUNDA ÖZTÜRK, MUSTAFA KEMAL SEZGİNTÜRK

引用次数: 0