Turkish journal of urology最新文献

{"title":"Lesion Volume in a Bi- or Multivariate Prediction Model for the Management of PI-RADS v2.1 Score 3 Category Lesions.","authors":"Eugenio Martorana,&nbsp;Maria Cristina Aisa,&nbsp;Riccardo Grisanti,&nbsp;Nicola Santini,&nbsp;Giacomo Maria Pirola,&nbsp;Alessandro Datti,&nbsp;Sandro Gerli,&nbsp;Alessandra Bonora,&nbsp;Aldo Burani,&nbsp;Giovanni Battista Scalera,&nbsp;Pietro Scialpi,&nbsp;Aldo Di Blasi,&nbsp;Michele Scialpi","doi":"10.5152/tud.2022.22038","DOIUrl":"https://doi.org/10.5152/tud.2022.22038","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed at improving the discrimination of Prostate Imaging - Reporting and Data System version 2.1 (PI-RADS v2.1) score 3 suspicious prostate cancer lesions using lesion volume evaluation.</p><p><strong>Material and methods: </strong>Two hundred five PI-RADS v2.1 score 3 lesions were submitted to transperineal MRI/TRUS fusion-targeted biopsy. The lesion volumes were estimated on diffusion-weighted imaging sequence and distributed in PI-RADS 3a (LV < 0.5 mL) and PI-RADS 3b (LV ≥ 0.5 mL) subcategories, using a 0.5 mL cutoff value. Data were retrospectively matched with histopathological findings from the biopsy. Assuming that lesions with LV < or ≥ 0.5 mL were respectively not eligible (benign and indolent PCa lesions) or eligible for biopsy (significant PCa lesions), the diagnostic accuracy of lesion volume in determining clinically significant PCa at biopsy was evaluated using a bi- or multivariate model.</p><p><strong>Results: </strong>About 55.1% and 44.9% of lesions were distributed in subcategories 3a and 3b, respectively. The overall PI-RADS score 3 detection rate was 273%. 3.5% (1.95% of total), and 25% (11.7% of total) significant PCa were found in PI-RADS 3a and 3b subcategory, respectively. The method showed 85.2% sensitivity, 61.2% specificity, 25% positive predictive value, and 96.5% negative predictive value and avoided 55.1% of unnecessary biopsies. The diagnostic accuracy in determining significant PCa at biopsy was 73.2% or 86.5% depending on whether lesion volume was used alone or in combination with prostate volume and patient age in a multivariate model.</p><p><strong>Conclusion: </strong>0.5 mL lesion volume cutoff value significantly discriminates fusion-targeted biopsy need in PI-RADS v2.1 score 3 lesions and its diagnostic accuracy improves when it combines with prostate volume and age in a multivariate model.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 4","pages":"268-277"},"PeriodicalIF":1.3,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40673388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oligometastatic Prostate Cancer: Is there a Role for Surgery? A Narrative Review.","authors":"Eugenio Martorana,&nbsp;Morgan Bruschi,&nbsp;Pietro Scialpi,&nbsp;Riccardo Grisanti,&nbsp;Michele Scialpi","doi":"10.5152/tud.2022.22064","DOIUrl":"https://doi.org/10.5152/tud.2022.22064","url":null,"abstract":"<p><p>Oligometastatic prostate cancer is commonly considered a transition between high metastatic and local- ized disease and includes a large spectrum of conditions with a polymorphic clinical behavior. The current management of these patients contemplates systemic therapy (i.e., androgen-deprivation drugs, chemothera- peutic drugs, or both treatments administered simultaneously) which have been shown to improve survival. Radiotherapy has also been introduced, into a multimodal setting, among the therapeutic treatments forpatients who are defined as oligometastatic prostate cancer according to Chemohormonal Therapy Versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer (CHAARTED) criteria.The role of surgical debulking in patients with oligometastatic prostate cancer has always been considered impracticable, both for a marginal therapeutic role and for the greater risk of sequelae and/or complications related to the procedure itself. Several authors have demonstrated some mechanisms by which the persistence of the primary tumor can facilitate the clinical progression of the disease itself and promote carcinogenesis, differentiation, migration, and angiogenesis in prostate cancer. From these studies emerges the hypothesis of a possible therapeutic advantage in oncological terms also for cytoreductive radical prostatectomy, in a multimodal therapy setting, compared to systemic therapy alone. The present review summarizes the main knowledge regarding the safety, feasibility, and oncological outcomes of cytoreductive radical prostatectomy in oligometastatic prostate cancer patients.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"174-179"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric Analysis of Prostate Zonal Anatomy After Transurethral Resection of Prostate and Holmium Laser Enucleation of Prostate Using Magnetic Resonance Imaging: A Pilot Study.","authors":"Abhishek Bhat,&nbsp;Jonathan E Katz,&nbsp;Vedant K Acharya,&nbsp;Khushi Shah,&nbsp;Ruben Blachman Braun,&nbsp;Nicholas Anthony Smith,&nbsp;R Patricia Castillo,&nbsp;Hemendra N Shah","doi":"10.5152/tud.2022.21326","DOIUrl":"https://doi.org/10.5152/tud.2022.21326","url":null,"abstract":"<p><strong>Objective: </strong>The primary purpose was to compare the completeness of adenomectomy and zonal anatomy of prostate on magnetic resonance imaging prostate after transurethral resection of prostate and Holmium enucleation of prostate. The secondary purpose was to investigate the relationship between preoperative total prostate volume and postoperative transition zone and peripheral zone volume after both procedures.</p><p><strong>Material and methods: </strong>A retrospective review of all patients who underwent transurethral resection of pros- tate or Holmium enucleation of prostate over 3 years (2017-2020) and had at least 1 postoperative magnetic resonance imaging prostate was performed. Volume estimations of the prostate and individual zones were per- formed, and statistical comparisons were made to evaluate morphometric changes between the 2 procedures.</p><p><strong>Results: </strong>A total of 9 patients (mean age, 71.8 years) underwent transurethral resection of prostate and 12 patients (mean age, 66.9 years) underwent Holmium enucleation of prostate. The median pre-operative prostate volume in the Holmium enucleation of prostate group was higher than the transurethral resection of prostate group (101.5 g vs. 62 g; P =.102). However, there was a significant difference in the resected tissue weight favoring Holmium enucleation of prostate over transurethral resection of prostate (P value=.004). The postoperative transition zone and peripheral zone volume as calculated by magnetic resonance imaging remained relatively constant in both procedures. The peripheral zone volume on postoperative magnetic res- onance imaging was found to be independent of transition zone volume even for very large-sized prostates.</p><p><strong>Conclusion: </strong>A well-performed transurethral resection of prostate or Holmium enucleation of prostate cannearly completely eliminate the transition zone volume, irrespective of the size of the prostate as confirmed by magnetic resonance imaging prostate. Additionally, the peripheral zone volume is consistent across the entire spectrum of the prostate size.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"201-208"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical and Functional Outcomes of Artery Only Versus Artery and Vein Clamping in Patients Undergoing Partial Nephrectomy: A Systematic Review and Meta-Analysis.","authors":"Abdalla Ali Deb,&nbsp;Ayman Agag,&nbsp;Naufal Naushad,&nbsp;Hosam Serag","doi":"10.5152/tud.2022.22009","DOIUrl":"https://doi.org/10.5152/tud.2022.22009","url":null,"abstract":"<p><p>Clamping of renal vessels during partial nephrectomy is usually performed to improve the visualization of tumor margins. However, clamping of renal vessels has been associated with detrimental effects on renal function after surgery. This study aimed to compare artery only versus artery and vein clamping as regards the surgical and functional outcomes in patients undergoing partial nephrectomy. The literature was searched for English published studies from January 1, 2000 to August 7, 2021. The search included MEDLINE/ PubMed, Cochrane Library, Scopus, Web of Science, Google Scholar, and ProQuest, using the terms {\"par- tial nephrectomy\"} OR {\"nephron-sparing surgery\"} AND {\"renal artery and vein clamping} AND {\"renal artery only clamping}. Nine studies were included. Meta-analysis showed the artery only clamping grouphad a significantly less percentage of change in glomerular filtration rate at last follow-up (standardizedmean difference: -0.42 [95% CI: -0.70, -0.13], P = .004) as well as a rate of postoperative complications(odds ratio: 0.64 [95% CI: 0.41, 0.98], P = .04). However, no significant difference was observed regarding the development of chronic kidney disease. There was no significant difference regarding the warm ischemiatime, blood loss, or positive surgical margin. Artery only clamping has a comparable safety to artery and vein clamping and may produce a renoprotective effect. Due to limitations of the included studies, the conduction of large-size randomized clinical trials with a long duration of follow-up is required before recommending the replacement of artery and vein clamping with artery only clamping during partial nephrectomy.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"180-195"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turkish Validation of the User Version of the Mobile Application Rating Scale.","authors":"Gokhan Calik,&nbsp;Betul Bersan Kartal,&nbsp;Stoyan Stoyanov,&nbsp;Stavros Gravas,&nbsp;Lavin Othman,&nbsp;Jean de la Rosette,&nbsp;Selami Albayrak,&nbsp;Pilar Laguna","doi":"10.5152/tud.2022.21324","DOIUrl":"https://doi.org/10.5152/tud.2022.21324","url":null,"abstract":"<p><strong>Objective: </strong>As the number of mobile health applications increases, quality assessment becomes a capital feature of any mobile application design. Besides the professional evaluation conducted before marketing the app, the perceptions of the subjects to whom is intended will determine the successful widespread dis- semination. Hence, the implementation of a given app may be impaired by the lack of a validated transla- tion and cross-cultural adaptation. We aimed to validate in the Turkish language the User Version of the Mobile Application Rating Scale, an English original scale designed to assess the quality of mobile health applications.</p><p><strong>Materials and methods: </strong>A well-established and predefined process of cross-cultural adaptation and transla- tion to Turkish of the User Version of the Mobile Application Rating Scale according to the World Health Organization guidelines was performed using a common, readily available, free-of-charge application. Internal consistency and reliability were tested in a population sample by Cronbach's α and rWG index, respectively.</p><p><strong>Results: </strong>The total User Version of the Mobile Application Rating Scale score had good internal consistency (Cronbach's α = 0.87). Internal consistencies of its subscales were also acceptable: with Cronbach's α of 0.71, 0.78, 0.71, and 0.73 for engagement, functionality, aesthetics, and information, respectively. Cronbach's α of the satisfaction subscale was 0.46. The User Version of the Mobile Application Rating Scale total and sub- scales scores had a strong within-group agreement, all of them with rwg indexes between 0.78 and 0.87 over baseline to 1 month.</p><p><strong>Conclusion: </strong>The Turkish version of the User Version of the Mobile Application Rating Scale is consistent with the English original version and is a reliable and valid tool to assess the quality of mobile applications by Turkish users.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"236-242"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10365113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calcified Peyronie's Disease Frequency on Computed Tomography.","authors":"Elif Gündoğdu,&nbsp;Emre Emekli","doi":"10.5152/tud.2022.21346","DOIUrl":"https://doi.org/10.5152/tud.2022.21346","url":null,"abstract":"<p><strong>Objective: </strong>In computed tomography examinations performed for various reasons, calcified Peyronie's dis-ease can be incidentally detected. In this study, we aimed to evaluate the frequency of calcified Peyronie'sdisease incidentally detected in patients with abdominal computed tomography.</p><p><strong>Material and methods: </strong>The images of male patients undergoing abdominal computed tomography betweenJanuary 2019 and January 2020 were retrospectively evaluated for the presence of calcified Peyronie's dis-ease. 1968 patients remained after subtracting computed tomography scans for insufficient evaluation of the penis, evaluated for the presence of calcified Peyronie's disease by two radiologists based on consensus. Thelocalization, side, and the number of plaques were recorded.</p><p><strong>Results: </strong>The computed tomography examination of 1968 patients revealed calcified Peyronie's disease in 130 (6.6%) patients. Peyronie's disease was bilateral in 73 patients (56.1%), and unilateral in 57 (43.9%). A single plaque was observed in 44 (33.9%) patients, and multiple plaques in 86 (66.1%). The plaques werelocated in the middle portion of the penis in 98, proximal penis in 92, and distal penis in 31 cases.</p><p><strong>Conclusion: </strong>Calcified Peyronie's disease is incidentally detected on computed tomography examinations at a rate not rare. Peyronie's disease tends to be multiple, bilateral, and localized in the middle portion of thepenis.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"196-200"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acellular Tissue Engineered Pericardial Patch Urethroplasty: A New Horizon of Substitution Urethroplasty.","authors":"Sunirmal Choudhury,&nbsp;Eeshansh Khare,&nbsp;Dilip Kumar Pal","doi":"10.5152/tud.2022.22018","DOIUrl":"https://doi.org/10.5152/tud.2022.22018","url":null,"abstract":"<p><strong>Objective: </strong>Buccal mucosal graft is the best autologous material for substitution urethroplasty. However, in cases where buccal mucosa is unavailable, a non-autologous tissue like acellular tissue-engineered pericar- dial patch can be very helpful. Our study is a small approach regarding the success and durability of acellular tissue-engineered pericardial patch as a substitution tissue in urethroplasty.</p><p><strong>Material and methods: </strong>A total of 22 patients underwent acellular tissue-engineered pericardial patch substi- tution urethroplasty using dorsolateral onlay technique for long segment urethral stricture, for a period of twoyears. Observations and comparison were made in terms of postoperative change in maximum urinary flowrate (Qmax), resolution of obstructive lower urinary tract symptoms, improvement in retrograde urethrogram and complications encountered, with buccal mucosal graft urethroplasty as a historical control.</p><p><strong>Results: </strong>Out of these 22 patients, 18 patients had successful outcomes considering maximum flow rate (Qmax)> 10 mL/s on uroflowmetry, resolved obstructive lower urinary tract symptoms, and normal postoperativeretrograde urethrogram, whereas four patients were considered a failure because of Qmax <10 mL/s, unre- solved obstructed lower urinary tract symptoms and recurrence of urethral stricture on retrograde urethro-gram and development of urethrocutaneous fistula.</p><p><strong>Conclusion: </strong>Acellular tissue-engineered pericardial patch substitution urethroplasty can be a useful alternative to autologous tissue substitution, especially where the buccal mucosal graft is unavailable for urethroplasty.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"222-228"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10365114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous nephrostomy in Ureteropelvic junction obstruction with poorly functioning kidney: Is it still pertinent in adults?","authors":"Uday Pratap Singh,&nbsp;Shitangsu Kakoti,&nbsp;Sanjoy Kumar Sureka,&nbsp;Nayab Danish,&nbsp;Abhay Kumar,&nbsp;Zain Tamboli,&nbsp;Madhur Anand,&nbsp;Aneesh Srivastava","doi":"10.5152/tud.2022.22050","DOIUrl":"https://doi.org/10.5152/tud.2022.22050","url":null,"abstract":"Objective: To determine the pertinence of percutaneous nephrostomy drainage in adult patients of primary ureteropelvic junction obstruction with poorly functioning kidneys (<20% split renal function). Material and methods: Clinical records of all patients with primary ureteropelvic junction obstruction with poorly functioning kidneys who underwent percutaneous nephrostomy drainage in our institute between February 2015 and January 2020 were retrospectively reviewed. The patients were divided into 4 groups according to their split renal function obtained from the Tc-99m ethylenedicysteine diuretic renogram. Group I consisted of all patients having split renal function ≤5%, group II with split renal function 6-10%, group III with split renal function 11-15%, and finally group IV with split renal function 16-20%. Those patients in whom split renal function was improved by >10% and had daily percutaneous nephrostomy output >400 mL, underwent pyeloplasty and the rest underwent nephrectomy. Results: Seventy-two patients were studied, out of which 5 were in group I, 20 in groups II and III each, and 27 in group IV. The mean age of presentation was 34.4 ± 14 years. The split renal function improvement of >10% was seen in 55 patients (76.4%) after percutaneous nephrostomy drainage (P < .05). Pyeloplasty was done in 40 patients (55.6%) and nephrectomy was done in 32 patients (44.4%). Conclusion: In conclusion, we recommend the use of a Tc-99m ethylenedicysteine scan for estimation of split renal function during the initial presentation in every patient followed by reconstructive surgery if split renal function is above 15% and nephrectomy if it is below 5%. The trial of percutaneous nephrostomy is pertinent if split renal function is between 6% and 15%.","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"229-235"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10365115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes of Prostatic Artery Embolization in Patients with Benign Prostatic Hyperplasia: A Prospective Clinical Study.","authors":"Kazım Dogan,&nbsp;Ahmet Erbagci,&nbsp;Haluk Sen,&nbsp;Selim Kervancioglu,&nbsp;Mehmet Sakıp Erturhan,&nbsp;İlker Seckiner,&nbsp;Ömer Bayrak","doi":"10.5152/tud.2022.22004","DOIUrl":"https://doi.org/10.5152/tud.2022.22004","url":null,"abstract":"<p><strong>Objective: </strong>To determine the clinical outcomes of prostatic artery embolization applied to patients with Material and methods: The study includes 30 patients diagnosed with benign prostatic hyperplasia in the urology clinic between 2012 and 2016, for whom anesthesia was contraindicated due to advanced age and comorbidities and who underwent prostatic artery embolization. These patients were evaluated before the procedure and in the 1st, 3rd, 6th, and 12th months after the procedure.</p><p><strong>Results: </strong>The mean prostate volume of the patients was 68 cm3 before the procedure and 45 cm3 12 monthsafter the procedure. A statistically significant decrease was observed (P = .001). The mean prostate-specific antigen value was 4.9 ng/dL before the procedure and 2.8 ng/dL 12 months after the procedure (P = .008). The mean Qmax value was 0 mL/s before the procedure and 12 mL/s 12 months after the procedure (P = .001). The mean international prostatic symptom scores value was 35 before and 16 twelve months after the proce-dure (P = .001). While the international index of erectile function value was 8.25 before the procedure, it was8.46 12 months after the procedure (P = .32). The quality of life index value was measured as 3.02 before theprocedure and 3.09 twelve months after the procedure; a statistically significant difference was determined (P = .027).</p><p><strong>Conclusion: </strong>Prostatic artery embolization, which is a minimally invasive procedure, can be applied as a safe and effective method to patients with benign prostatic hyperplasia who cannot tolerate anesthesia due to advanced age and comorbidities.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"215-221"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Review on Current Controversies and Debate in Prostate Artery Embolization.","authors":"Drew Maclean,&nbsp;Charles Timothy Francis Bryant,&nbsp;Ganesh Vigneswaran,&nbsp;Timothy Jc Bryant,&nbsp;Mark Harris,&nbsp;Bhaskar Somani,&nbsp;Sachin Modi","doi":"10.5152/tud.2022.21337","DOIUrl":"https://doi.org/10.5152/tud.2022.21337","url":null,"abstract":"<p><p>Prostate artery embolization is emerging as one of the most effective therapies amidst a new era of mini- mally invasive benign prostate hyperplasia treatment and technology. However, several current controver- sies remain unanswered which could impact the widespread adoption of this novel and unique transarterial(rather than transurethral) intervention. This is reflected in the differences between the UK (NICE), European (EAU), and American (AUA) guidelines, the latter of which only recommends the use of prostate arteryembolization in a clinical trial setting. The main issues include questions over the duration of symptom response, cost-effectiveness, mechanism of action, patient selection, and other procedural technical consid- erations. These factors are the most pressing faced by proponents of prostate artery embolization, and we seek to highlight why their resolution is important to ensure men with benign prostate hyperplasia seeking a minimally invasive solution are optimally informed and most effectively managed.</p>","PeriodicalId":23366,"journal":{"name":"Turkish journal of urology","volume":"48 3","pages":"166-173"},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}