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Turkish Journal of Hematology最新文献

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Images of Temporomandibular Joint Arthropathy in a Severe Hemophilia B Patient with Inhibitor and a Type III Von Willebrand Patient with Inhibitor. 一名严重血友病 B 型患者（含抑制剂）和一名 III 型 Von Willebrand 患者（含抑制剂）的颞下颌关节关节病图像。
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-09-25 DOI: 10.4274/tjh.galenos.2024.2024.0342
Selda Yenel, Dilek Aynur Çankal, Zühre Akarslan, Merve Yazol, Zühre Kaya
{"title":"Images of Temporomandibular Joint Arthropathy in a Severe Hemophilia B Patient with Inhibitor and a Type III Von Willebrand Patient with Inhibitor.","authors":"Selda Yenel, Dilek Aynur Çankal, Zühre Akarslan, Merve Yazol, Zühre Kaya","doi":"10.4274/tjh.galenos.2024.2024.0342","DOIUrl":"https://doi.org/10.4274/tjh.galenos.2024.2024.0342","url":null,"abstract":"","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripheral Hemophagocytosis and Leukemic Blasts from Urine in de novo Pure Erythroid Leukemia. 新生纯红细胞白血病患者的外周血嗜细胞增多症和尿液中的白血病碎块
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-09-19 DOI: 10.4274/tjh.galenos.2024.2024.0126
Mei Yang, Yujing Tian, Fengling Hou, Lin Zhong, Jingyan Li, Xiaohong Li
{"title":"Peripheral Hemophagocytosis and Leukemic Blasts from Urine in <i>de novo</i> Pure Erythroid Leukemia.","authors":"Mei Yang, Yujing Tian, Fengling Hou, Lin Zhong, Jingyan Li, Xiaohong Li","doi":"10.4274/tjh.galenos.2024.2024.0126","DOIUrl":"https://doi.org/10.4274/tjh.galenos.2024.2024.0126","url":null,"abstract":"","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eosinophilia with STAT5BN642H Mutation: A Heterogeneous Entity with Overlapping Morphological Features and Poor Outcome. 嗜酸性粒细胞增多伴 STAT5BN642H 基因突变：形态特征重叠且预后不佳的异质性实体
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-08-29 DOI: 10.4274/tjh.galenos.2024.2024.0204
Venkat Shashidhar, Aishwarya Karthikeyan, Anand Balakrishnan, Sudhanshi Raina, Jasmina Ahluwalia, Reena Das, Pankaj Malhotra, Sreejesh Sreedharanunni
{"title":"Eosinophilia with <i>STAT5B</i>N642H Mutation: A Heterogeneous Entity with Overlapping Morphological Features and Poor Outcome.","authors":"Venkat Shashidhar, Aishwarya Karthikeyan, Anand Balakrishnan, Sudhanshi Raina, Jasmina Ahluwalia, Reena Das, Pankaj Malhotra, Sreejesh Sreedharanunni","doi":"10.4274/tjh.galenos.2024.2024.0204","DOIUrl":"https://doi.org/10.4274/tjh.galenos.2024.2024.0204","url":null,"abstract":"","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deficiency of Adenosine Deaminase 2 腺苷脱氨酶 2 缺乏症。
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-08-28 Epub Date: 2024-08-09 DOI: 10.4274/tjh.galenos.2024.2024.0265
Çağrı Coşkun, Şule Ünal
{"title":"Deficiency of Adenosine Deaminase 2","authors":"Çağrı Coşkun, Şule Ünal","doi":"10.4274/tjh.galenos.2024.2024.0265","DOIUrl":"10.4274/tjh.galenos.2024.2024.0265","url":null,"abstract":"<p><p>Adenosine deaminase 2 (<i>ADA2</i>) deficiency is an autosomal recessively inherited autoinflammatory disorder caused by loss-of-function mutations in the <i>ADA2</i> gene. Although the pathogenesis involves the triggering of a proinflammatory cascade due to increased production of inflammatory cytokines such as tumor necrosis factor (TNF)-α and dysregulation of neutrophil extracellular trap formation resulting from an excess accumulation of extracellular adenosine, the pathogenetic mechanism still needs further clarification due to the broad clinical spectrum. In addition to the initially described vasculitis-related symptoms, hematological, immunological, and autoinflammatory symptoms are now well recognized. The diagnosis is made by demonstration of pathogenic variants of <i>ADA2</i> with biallelic loss of function and identification of low plasma <i>ADA2</i> catalytic activity. Currently, TNF-α inhibitors are the treatment of choice for controlling vasculitis manifestations and preventing strokes. However, in patients presenting with severe hematologic findings, TNF-α inhibitors are not the treatment of choice and hematopoietic stem cell transplantation has been shown to be successful in selected cases. Recombinant <i>ADA2</i> protein and gene therapy are promising treatment modalities for the future. In conclusion, <i>ADA2</i> deficiency has a broad phenotype and should be considered in the differential diagnosis of different clinical situations. In this review, we summarize the disease manifestations of <i>ADA2</i> deficiency and available treatment options.</p>","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141907783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epstein-Barr Virus-Induced Warm Autoimmune Hemolytic Anemia Epstein Barr 病毒诱发的温热性自身免疫性溶血性贫血。
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-08-28 Epub Date: 2024-06-28 DOI: 10.4274/tjh.galenos.2024.2024.0136
Kazi Bilal, Chakrapani Anupam, Ramasubban Suresh, Das Sudipta, Kazi Chishti Marzooka
{"title":"Epstein-Barr Virus-Induced Warm Autoimmune Hemolytic Anemia","authors":"Kazi Bilal, Chakrapani Anupam, Ramasubban Suresh, Das Sudipta, Kazi Chishti Marzooka","doi":"10.4274/tjh.galenos.2024.2024.0136","DOIUrl":"10.4274/tjh.galenos.2024.2024.0136","url":null,"abstract":"","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141474680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-CD22 Calicheamicin-Inotuzumab Ozogamicin Combined with Venetoclax + Azacitidine in the Treatment of Mixed-Phenotype Acute Leukemia: A Case Report 抗 CD22 Calecheamicin-Inotuzumab Ozogamicin 联合 Venetoclax+Azatabine 治疗混合表型急性白血病：病例报告。
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-08-28 Epub Date: 2024-07-30 DOI: 10.4274/tjh.galenos.2024.2024.0044
Kongfei Li, Yuxiao Wang, Renzhi Pei, Ying Lu, Junjie Cao, Xianxu Zhuang, Jiaying Lian, Bibo Zhang
{"title":"Anti-CD22 Calicheamicin-Inotuzumab Ozogamicin Combined with Venetoclax + Azacitidine in the Treatment of Mixed-Phenotype Acute Leukemia: A Case Report","authors":"Kongfei Li, Yuxiao Wang, Renzhi Pei, Ying Lu, Junjie Cao, Xianxu Zhuang, Jiaying Lian, Bibo Zhang","doi":"10.4274/tjh.galenos.2024.2024.0044","DOIUrl":"10.4274/tjh.galenos.2024.2024.0044","url":null,"abstract":"","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Cause of Giant Intrathoracic Mass in a Woman with Sickle Cell Disease: Extramedullary Hematopoiesis 镰状细胞病女性患者胸腔内巨大肿块的罕见病因：髓外造血。
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-08-28 Epub Date: 2024-05-07 DOI: 10.4274/tjh.galenos.2024.2024.0127
Furkan Ufuk, İclal Ocak, Lydia Chelala, Luis Landeras
{"title":"A Rare Cause of Giant Intrathoracic Mass in a Woman with Sickle Cell Disease: Extramedullary Hematopoiesis","authors":"Furkan Ufuk, İclal Ocak, Lydia Chelala, Luis Landeras","doi":"10.4274/tjh.galenos.2024.2024.0127","DOIUrl":"10.4274/tjh.galenos.2024.2024.0127","url":null,"abstract":"","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cleaved Leukemic Blast Cells, Vacuolation, and Pseudopodia-like Cytoplasmic Projections in Acute Myeloid Leukemia with TLS::ERG 患有 TLS::ERG 的急性髓性白血病中的白血病碎裂细胞、空泡化和假鞭毛样胞质突起。
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-08-28 Epub Date: 2024-01-30 DOI: 10.4274/tjh.galenos.2024.2023.0386
Xingqin Huang, Linglin Jiang, Ting Li, Mei Yang
{"title":"Cleaved Leukemic Blast Cells, Vacuolation, and Pseudopodia-like Cytoplasmic Projections in Acute Myeloid Leukemia with <i>TLS::ERG</i>","authors":"Xingqin Huang, Linglin Jiang, Ting Li, Mei Yang","doi":"10.4274/tjh.galenos.2024.2023.0386","DOIUrl":"10.4274/tjh.galenos.2024.2023.0386","url":null,"abstract":"","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139576788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Turkish Hematologists’ Preferences for Related Donor Selection: Results of a Multicenter Survey 土耳其血液学专家对亲属捐献者选择的偏好：多中心调查结果。
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-08-28 Epub Date: 2024-05-27 DOI: 10.4274/tjh.galenos.2024.2024.0099
Sıdıka Gülkan Özkan, Ali Kimiaei, Ali Hakan Kaya, Mehmet Sezgin Pepeler, Hasan Atilla Özkan, Mutlu Arat
{"title":"Turkish Hematologists’ Preferences for Related Donor Selection: Results of a Multicenter Survey","authors":"Sıdıka Gülkan Özkan, Ali Kimiaei, Ali Hakan Kaya, Mehmet Sezgin Pepeler, Hasan Atilla Özkan, Mutlu Arat","doi":"10.4274/tjh.galenos.2024.2024.0099","DOIUrl":"10.4274/tjh.galenos.2024.2024.0099","url":null,"abstract":"<p><p>Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a widely utilized treatment for various hematological diseases. While selection criteria for unrelated donors are well established, there is a lack of consistency and standardization in the selection of related donors. This study investigated the current approach of hematologists to the selection of related donors at Turkish HSCT centers. The study employed a cross-sectional survey design, distributing a self-administered questionnaire to 95 adult and pediatric transplantation centers in Türkiye to investigate their approaches to related donor selection for allo-HSCT. The questionnaire collected data on various topics including the center’s experience in performing allo-HSCT, patient groups treated, number of allo-HSCT procedures conducted between 2015 and 2021, preferences for related donors, considerations in related donor selection (such as sex and past pregnancies), guidelines utilized for related donor selection, upper age limit for related donors, and the use of specialized advanced analyses for elderly donors. The response rate to the survey was 38.9%. Variability was observed across centers in terms of sex consideration and the impact of past pregnancies on related female donor rejection. Different guidelines were employed for related donor selection, with the European Bone Marrow Transplantation guidelines being the most commonly used. Regarding the upper age limit for related donors, 8.1% of centers accepted an upper age limit of 55 years, 48.7% preferred an upper age limit of 65 years, and 43.2% selected related donors aged 65 and above. The lack of standardized guidelines for related donor selection in HSCT centers leads to variability in criteria and potential risks. Collaboration among centers is essential to establish consensus and develop standardized protocols.</p>","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obinutuzumab for the Treatment of Cold Agglutinin Disease: A Case Report 奥比妥珠单抗治疗冷凝集素病：病例报告。
IF 1.5 4区 医学
Turkish Journal of Hematology Pub Date : 2024-08-28 Epub Date: 2024-06-14 DOI: 10.4274/tjh.galenos.2024.2024.0132
Siyuan Li, Kaini Shen, Lu Zhang
{"title":"Obinutuzumab for the Treatment of Cold Agglutinin Disease: A Case Report","authors":"Siyuan Li, Kaini Shen, Lu Zhang","doi":"10.4274/tjh.galenos.2024.2024.0132","DOIUrl":"10.4274/tjh.galenos.2024.2024.0132","url":null,"abstract":"","PeriodicalId":23362,"journal":{"name":"Turkish Journal of Hematology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141318423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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