A Rare Case of Non-Hodgkin Lymphoma Presenting as a Mass Originating from the Corpus Cavernosum.

Abstract

Malignant neoplasms of the penis are uncommon, the most common being squamous cell carcinoma. Non-Hodgkin's lymphoma occurs in extranodal sites in half of patients, but is extremely rare in the penis. Here, a 24 years old case of a penile mass is reported as non-Hodgkin lymphoma. On physical examination and imaging, two-centimeter lesion was detected on the left distal corpus cavernosum of the penis and extending to the proximal corpus cavernosum. Excisional biopsy from distal left corpus cavernosum performed under general anesthesia. Histopathological examination of the excision material revealed diffuse large B-cell lymphoma with a post-germinal center cell phenotype. Although it is rare in patients presenting with a penile mass, the possibility of lymphoma involvement should be kept in mind. It can mimic Peyronie's disease or corpus cavernosum thrombosis.