American Journal of Pharmacy And Health Research最新文献_第8页

Ocular Morbidity in Population of Uttarakhand 北阿坎德邦人口的眼部发病率

American Journal of Pharmacy And Health Research Pub Date : 1900-01-01 DOI: 10.46624/ajphr.2019.v7.i8.005

B. Pant, Dr. Prashant Mathur, Dr. Yogesh Joshi

{"title":"Ocular Morbidity in Population of Uttarakhand","authors":"B. Pant, Dr. Prashant Mathur, Dr. Yogesh Joshi","doi":"10.46624/ajphr.2019.v7.i8.005","DOIUrl":"https://doi.org/10.46624/ajphr.2019.v7.i8.005","url":null,"abstract":"The visual system is the portion of the central nervous system through which human organism is able to see. Eye is very sensitive organ of our system so the care is very important. The task of the visual system is a big one. This system must have an almost innumerable amount of available information and extract only the useful information. Most important special sense in human being is the vision. For normal physical, mental, psychological development and education, vision should be normal. The aim of this review is to evaluate the ocular morbidity in the population of Uttarakhand. This study is a literature review of published studies from 2013 to 2017, held in the different journal and article and websites. Refractive error was the commonest ocular morbidity followed by disorders of conjunctiva, congenital malformations of eye, disorders of eyelid, lacrimal system and orbit, injury of eye and orbit, superficial injury of eye, disorders of sclera, cornea, iris and ciliary body, disorders of choroid and retina and presence of functional implant. Most common complaint among children was watering of the eye followed by discharge from eyes, redness of eye and headache, diminished vision, itching and inability to see clearly in dim light. Prevalence of ocular morbidity was significantly associated with age. Commonest causes of injury were contact lens wear, road traffic accidents, sports playing & recreational activities and occupational. Delay in presentation was associated with complications. Stable intervention programs targeting refractive errors, allergic conjunctivitis, infections of lid and adnexa and trauma are used to decrease the burden of ocular morbidity.","PeriodicalId":233230,"journal":{"name":"American Journal of Pharmacy And Health Research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132914777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Development and Validated RP-HPLC Method for Simultaneous Estimation of Probenecid and Cefadroxil in Pure &Combined Dosage Form 建立反相高效液相色谱法同时测定丙苯酸和头孢地洛辛纯剂型和复方剂型的含量

American Journal of Pharmacy And Health Research Pub Date : 1900-01-01 DOI: 10.46624/ajphr.2019.v7.i9.003

Gurumurthy. Telugu, Dr Madhuri. D

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Probing the Binding of Two Antibiotics to Human – Holo Transferrin: A Combined Spectroscopic and Docking study. 两种抗生素与人全息转铁蛋白的结合:光谱与对接的联合研究。

American Journal of Pharmacy And Health Research Pub Date : 1900-01-01 DOI: 10.46624/ajphr.2019.v7.i9.002

S. Bakkialakshmi, T. Anupriya

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Antipsychotic drug induced sexual dysfunction 抗精神病药物引起性功能障碍

American Journal of Pharmacy And Health Research Pub Date : 1900-01-01 DOI: 10.46624/ajphr.2019.v7.i6.003

P. Mathur, Sandeep Uniyal

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Formulation and Comparative Evaluation of Diclofenac Aqua Gel by Using Various Polymers 不同聚合物双氯芬酸凝胶的制备及对比评价

American Journal of Pharmacy And Health Research Pub Date : 1900-01-01 DOI: 10.46624/ajphr.2019.v7.i7.001

S. More, M. Upadhyay, S. Ganguly

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Development, Characterization & Statistical Optimization of Matrix Type Transdermal Patches of Almotriptan Malate for The Treatment of Migraine 基质型苹果酸阿莫曲坦透皮贴剂治疗偏头痛的研制、表征及统计优化

American Journal of Pharmacy And Health Research Pub Date : 1900-01-01 DOI: 10.46624/ajphr.2019.v7.i6.001

Akila Rm, Naseem Ak

{"title":"Development, Characterization & Statistical Optimization of Matrix Type Transdermal Patches of Almotriptan Malate for The Treatment of Migraine","authors":"Akila Rm, Naseem Ak","doi":"10.46624/ajphr.2019.v7.i6.001","DOIUrl":"https://doi.org/10.46624/ajphr.2019.v7.i6.001","url":null,"abstract":"The present work is focused on the development, evaluation and statistical optimization of almotriptan malate transdermal patches. Almotriptan malate is used as anti-migraine drug and reported to have the best-sustained pain free rate and the lowest adverse events rate of all the triptans and thus making interest in the development of new route for the therapeutic administration of the drug, So, the present research work was aimed to develop matrix type transdermal patches using polymers HPMC K15M, ERS100 and EC and plasticizers DBP and PEG400 by solvent casting method. This formulation would help to avoid non-compliance of the tablet dosage form The IR spectra of the drug and physical mixtures of drug-polymer confirmed the absence of incompatibility between drug and polymers. The in-vitro drug release studies revealed that patches made of HPMC K15M-ERS 100 with DBP as plasticizer was considered as the best formulation and incorporated in 2 factorial design and evaluated for further studies. The concentration of HPMC K 15M and ERS 100 are chosen as the independent variables. Drug content, %moisture absorption %, moisture loss, and cumulative % drug released at 12h are chosen as dependent variables. The drug release from transdermal patches followed zero order kinetics. Various physicochemical parameters of the patches were investigated. The current research work of transdermal patches of almotriptan malate may provide sustained delivery for prolonged periods in the management of migraine, which can be a good way to bypass the extensive hepatic first-pass metabolism.","PeriodicalId":233230,"journal":{"name":"American Journal of Pharmacy And Health Research","volume":"2 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132238006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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