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Screening for Chagas disease in Latin-American pregnant women and their newborns: A prospective observational, multicenter study in Milan, Italy 拉丁美洲孕妇及其新生儿查加斯病筛查:意大利米兰的一项前瞻性观察性多中心研究
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-26 DOI: 10.1016/j.tmaid.2025.102846
Federico Sabaini , Andrea Giacomelli , Beatrice Tassis , Mariagrazia Ierardi , Anna Maria Marconi , Andrea Ronchi , Irene Cetin , Lea Testa , Valeria Savasi , Elisa Fabbri , Giulia Alabiso , Greta Nova , Michele Vignali , Nikita Alfieri , Vania Giacomet , Martina Beltrami , Giacomo Casalini , Margherita Longo , Silvia Grosso , Romualdo Grande , Spinello Antinori
{"title":"Screening for Chagas disease in Latin-American pregnant women and their newborns: A prospective observational, multicenter study in Milan, Italy","authors":"Federico Sabaini ,&nbsp;Andrea Giacomelli ,&nbsp;Beatrice Tassis ,&nbsp;Mariagrazia Ierardi ,&nbsp;Anna Maria Marconi ,&nbsp;Andrea Ronchi ,&nbsp;Irene Cetin ,&nbsp;Lea Testa ,&nbsp;Valeria Savasi ,&nbsp;Elisa Fabbri ,&nbsp;Giulia Alabiso ,&nbsp;Greta Nova ,&nbsp;Michele Vignali ,&nbsp;Nikita Alfieri ,&nbsp;Vania Giacomet ,&nbsp;Martina Beltrami ,&nbsp;Giacomo Casalini ,&nbsp;Margherita Longo ,&nbsp;Silvia Grosso ,&nbsp;Romualdo Grande ,&nbsp;Spinello Antinori","doi":"10.1016/j.tmaid.2025.102846","DOIUrl":"10.1016/j.tmaid.2025.102846","url":null,"abstract":"<div><h3>Objectives</h3><div>Chagas Disease (CD), caused by <em>Trypanosoma cruzi</em>, is endemic in Latin America (LA). However, due to migration, it is now present globally. We aimed to evaluate the prevalence of CD among LA pregnant women in Milan, Italy, and the incidence of <em>T. cruzi</em> transmission to their newborns.</div></div><div><h3>Methods</h3><div>A prospective multicenter observational study was conducted in five different Obstetrics and Gynecology outpatient clinics in Milan, Italy between September 2019 and October 2024. Pregnant women from endemic areas for CD were tested by means of two serological tests directed against <em>T. cruzi</em> antigens. Newborns from positive <em>T. cruzi</em> mothers were screened for <em>T. cruzi</em> infection at birth and at 1, 3 and 9 months.</div></div><div><h3>Results</h3><div>339 women underwent screening for <em>T. cruzi</em> infection with a median age of 33 years [IQR 28–37 years]. Most of them came from Peru (38.3 %), followed by El Salvador (20.6 %) and Ecuador (19.5 %). Six of them tested positive for <em>T. cruzi</em>, accounting for an estimated prevalence of 1.77 % (95 % CI 0.37 %–3.17 %). Two of the affected women were from Bolivia, and the remaining from El Salvador, Brazil, Ecuador and Peru. All 6 children had a negative PCR for <em>T. cruzi</em> infection, and their serology turned negative within the first year of life.</div></div><div><h3>Conclusions</h3><div>The seroprevalence of <em>T. cruzi</em> infection among LA pregnant women in Milan is significant, underscoring the potential occurrence of congenital CD in a non-endemic area like Italy. Raising awareness of this neglected tropical disease among LA women, midwives and gynecologists is crucial.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102846"},"PeriodicalIF":6.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143726082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New World screwworm (Cochliomyia hominivorax) infestation in a returned traveller from Costa Rica 哥斯达黎加归国旅行者的新世界螺旋虫感染
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-21 DOI: 10.1016/j.tmaid.2025.102843
Amna Majeed , George Ho , Antoine Corbeil , Isaac I. Bogoch
{"title":"New World screwworm (Cochliomyia hominivorax) infestation in a returned traveller from Costa Rica","authors":"Amna Majeed ,&nbsp;George Ho ,&nbsp;Antoine Corbeil ,&nbsp;Isaac I. Bogoch","doi":"10.1016/j.tmaid.2025.102843","DOIUrl":"10.1016/j.tmaid.2025.102843","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102843"},"PeriodicalIF":6.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polish travellers on the move: A study of knowledge of travel health and associated practices among polish travellers abroad 移动中的波兰旅行者:对国外波兰旅行者的旅行健康知识和相关做法的研究。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-20 DOI: 10.1016/j.tmaid.2025.102842
Anna Bogacka , Agnieszka Wroczyńska , Maciej Grzybek
{"title":"Polish travellers on the move: A study of knowledge of travel health and associated practices among polish travellers abroad","authors":"Anna Bogacka ,&nbsp;Agnieszka Wroczyńska ,&nbsp;Maciej Grzybek","doi":"10.1016/j.tmaid.2025.102842","DOIUrl":"10.1016/j.tmaid.2025.102842","url":null,"abstract":"<div><h3>Background</h3><div>Post-pandemic travel has surged, with 1.3 billion journeys recorded worldwide in 2023, reflecting a growing interest in tropical destinations despite the associated health risks. Access to travel health information has improved, yet adherence to preventive measures remains limited due to misinformation, insufficient pre-travel consultations, and concerns about malaria prophylaxis. Based on data from a three-year survey, this study examines the attitudes of Polish travellers to vaccinations, malaria prophylaxis, and COVID-19-related measures.</div></div><div><h3>Methods</h3><div>Surveys conducted during travel festivals from 2021 to 2023 targeted adult participants. A questionnaire designed by experts in travel medicine addressed the demographics, travel behaviours, and health-related practices. Statistical analyses, including chi-squared tests and logistic regression, explored the impact of demographic factors on behaviours, using Python for data analysis.</div></div><div><h3>Results</h3><div>Among 644 participants (mean age 32; 48 % male), 49.5 % reported pre-travel vaccination and 281 intended to use malaria chemoprophylaxis. Gender significantly influenced vaccination status and travel to Africa. The most cited malaria prevention methods were repellents and mosquito nets. Illnesses were reported by 317 participants, with travellers' diarrhoea (185 cases) most common, particularly in Turkey, Egypt, and India. Forty-eight individuals required medical consultations.</div></div><div><h3>Conclusions</h3><div>Education and pre-travel counseling enhance adherence to preventive measures, yet many travellers fail to follow recommendations. Malaria remains the most common travel-imported disease in the EU/EEA, with 4856 cases in 2021. The Capability, Opportunity, and Motivation Behavior (COM-B) model highlights the importance of addressing these factors to improve compliance with preventive behaviours.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102842"},"PeriodicalIF":6.3,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of climate change on travel-related vector-borne diseases: A case study on dengue virus transmission 气候变化对旅行相关病媒传播疾病的影响:以登革热病毒传播为例
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-19 DOI: 10.1016/j.tmaid.2025.102841
Ebrahim Abbasi
{"title":"The impact of climate change on travel-related vector-borne diseases: A case study on dengue virus transmission","authors":"Ebrahim Abbasi","doi":"10.1016/j.tmaid.2025.102841","DOIUrl":"10.1016/j.tmaid.2025.102841","url":null,"abstract":"<div><h3>Introduction</h3><div>Climate change significantly affects global health, particularly through the increased transmission of vector-borne diseases like dengue fever. This study examines how climate change influences the geographical spread of <em>Aedes aegypti</em> mosquitoes, the main carriers of dengue, highlighting its implications for public health worldwide.</div></div><div><h3>Materials and methods</h3><div>This study employed a comprehensive approach to evaluate the effect of climate change on dengue transmission dynamics. It included environmental data analysis, mosquito population surveys, and dengue case reports. Remote sensing data was used to track changes in temperature, precipitation, and humidity in dengue-prone areas. Field surveys measured mosquito density, while molecular techniques assessed viral load in Aedes mosquitoes. Additionally, mathematical modeling predicted dengue's future spread under various climate scenarios.</div></div><div><h3>Results</h3><div>The findings indicate a significant correlation between rising temperatures, changing rainfall patterns, and the expansion of <em>Aedes aegypti</em> habitats, resulting in increased mosquito populations in previously non-endemic areas. This ecological shift is linked to a rise in dengue incidence in regions affected by climate change. Projections suggest a 25 % increase in dengue spread by 2050, especially in Southeast Asia, sub-Saharan Africa, and parts of South America.</div></div><div><h3>Discussion</h3><div>The study highlights the significant effects of climate change on mosquito distribution and the increasing rates of dengue fever. Warmer temperatures and altered rainfall patterns enhance mosquito growth and virus transmission, while global travel aids the spread of the virus. It emphasizes the necessity for early intervention strategies, including better surveillance, vector control, and adaptations to climate changes, to tackle future dengue transmission issues.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102841"},"PeriodicalIF":6.3,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infectious diseases prevention and vaccination in migrants in Latin America: The challenges of transit through the treacherous Darien gap, Panama 拉丁美洲移民的传染病预防和疫苗接种:通过巴拿马险恶的达连峡谷过境的挑战。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-18 DOI: 10.1016/j.tmaid.2025.102839
Alfonso J. Rodriguez-Morales , María Camila Puerta-Arias , Rola Husni , Juan J. Montenegro-Idrogo , Juan Pablo Escalera-Antezana , Lucia E. Alvarado-Arnez , D. Katterine Bonilla-Aldana , German Camacho-Moreno , Henry Mendoza , Ivan Arturo Rodriguez-Sabogal , Jose Millán-Oñate , Gustavo Lopardo , Octavio A. Arce , Sergio Cimerman , Tânia do Socorro Souza Chaves , Tomas Orduna , Susana Lloveras , Maritza Cabrera , Monica Thormann , Yasemin Özsürekçi , Jose A. Suarez
{"title":"Infectious diseases prevention and vaccination in migrants in Latin America: The challenges of transit through the treacherous Darien gap, Panama","authors":"Alfonso J. Rodriguez-Morales ,&nbsp;María Camila Puerta-Arias ,&nbsp;Rola Husni ,&nbsp;Juan J. Montenegro-Idrogo ,&nbsp;Juan Pablo Escalera-Antezana ,&nbsp;Lucia E. Alvarado-Arnez ,&nbsp;D. Katterine Bonilla-Aldana ,&nbsp;German Camacho-Moreno ,&nbsp;Henry Mendoza ,&nbsp;Ivan Arturo Rodriguez-Sabogal ,&nbsp;Jose Millán-Oñate ,&nbsp;Gustavo Lopardo ,&nbsp;Octavio A. Arce ,&nbsp;Sergio Cimerman ,&nbsp;Tânia do Socorro Souza Chaves ,&nbsp;Tomas Orduna ,&nbsp;Susana Lloveras ,&nbsp;Maritza Cabrera ,&nbsp;Monica Thormann ,&nbsp;Yasemin Özsürekçi ,&nbsp;Jose A. Suarez","doi":"10.1016/j.tmaid.2025.102839","DOIUrl":"10.1016/j.tmaid.2025.102839","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102839"},"PeriodicalIF":6.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A preliminary analysis of hand disinfection use by travellers and their colonisation-risk with multi-resistant bacteria: A proof-of-concept study 旅行者手部消毒使用及其多耐药细菌定殖风险的初步分析:一项概念验证研究。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-17 DOI: 10.1016/j.tmaid.2025.102837
Tobias Kaspers , Cosima Berdin , Thérèse Staub , Barbara Gärtner , Fabian Berger , Alexander Halfmann , Sören L. Becker , Sophie Schneitler
{"title":"A preliminary analysis of hand disinfection use by travellers and their colonisation-risk with multi-resistant bacteria: A proof-of-concept study","authors":"Tobias Kaspers ,&nbsp;Cosima Berdin ,&nbsp;Thérèse Staub ,&nbsp;Barbara Gärtner ,&nbsp;Fabian Berger ,&nbsp;Alexander Halfmann ,&nbsp;Sören L. Becker ,&nbsp;Sophie Schneitler","doi":"10.1016/j.tmaid.2025.102837","DOIUrl":"10.1016/j.tmaid.2025.102837","url":null,"abstract":"<div><h3>Background</h3><div>International travellers have the potential to transmit multidrug-resistant bacteria. However, the role of hygiene measures during travel has yet to be investigated.</div></div><div><h3>Method</h3><div>Travellers were asked about their use of disinfectants and hygiene behaviour. Stool samples were analysed for Gram-negative multi-resistant bacteria (MDRO). These data were analysed, and a new MDRO risk map was developed and compared with data from existing literature.</div></div><div><h3>Result</h3><div>Of 214 travellers, 6 (2.8 %) tested positive for an MDRO before and 16 (7.5 %) after the trip, with travel in known high-risk MDRO areas. Most travellers, 174 (81.3 %), regularly used disinfectants; only 36 (16.8 %) did not. There was no statistically significant correlation between the use of a disinfectant and colonisation with MDRO. In our and comparable studies, a high-risk region on the risk map was associated with an increased number of MDRO or extended-spectrum beta-lactamase (ESBL) positive returns.</div></div><div><h3>Conclusion</h3><div>Travellers showed a high willingness to use disinfectants. This preliminary study highlights the need for larger, randomized studies to better assess the true impact of hand disinfectants on MDRO acquisition.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102837"},"PeriodicalIF":6.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imported fever in returning travellers and migrants in Spain, 2009–2021. Analysis by the +REDIVI network 2009-2021年西班牙归国旅行者和移民的输入性发热。+REDIVI网络分析。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-15 DOI: 10.1016/j.tmaid.2025.102833
Pedro Guevara-Hernández , Jara Llenas-García , Marta Díaz-Menéndez , Nuria Serre-Delcor , Clara Crespillo-Andújar , Fernando Salvador , José Manuel Ruiz-Giardin , Josune Goikoetxea-Agirre , Diego Torrús-Tendero , Fernando de la Calle-Prieto , Inés Oliveira-Souto , Pau Bosch-Nicolau , Philip Wikman , José A. Pérez-Molina , the +Redivi study group
{"title":"Imported fever in returning travellers and migrants in Spain, 2009–2021. Analysis by the +REDIVI network","authors":"Pedro Guevara-Hernández ,&nbsp;Jara Llenas-García ,&nbsp;Marta Díaz-Menéndez ,&nbsp;Nuria Serre-Delcor ,&nbsp;Clara Crespillo-Andújar ,&nbsp;Fernando Salvador ,&nbsp;José Manuel Ruiz-Giardin ,&nbsp;Josune Goikoetxea-Agirre ,&nbsp;Diego Torrús-Tendero ,&nbsp;Fernando de la Calle-Prieto ,&nbsp;Inés Oliveira-Souto ,&nbsp;Pau Bosch-Nicolau ,&nbsp;Philip Wikman ,&nbsp;José A. Pérez-Molina ,&nbsp;the +Redivi study group","doi":"10.1016/j.tmaid.2025.102833","DOIUrl":"10.1016/j.tmaid.2025.102833","url":null,"abstract":"<div><h3>Background</h3><div>Travellers and migrants commonly present to health services with febrile syndrome, which can have different causes, including some that are life-threatening. A better understanding of these causes may help guide management and determine appropriate empirical treatments.</div></div><div><h3>Objectives</h3><div>The aim was to identify the leading causes of fever and to assess their association with the region of travel and type of travellers.</div></div><div><h3>Methods</h3><div>This prospective, multicentre study was conducted within the +REDIVI network. Data were collected on febrile syndrome cases among migrants, travellers, and people visiting friends and relatives (VFRs) from 2009 to 2021. Comparative analyses were performed according to patient categories and regions of travel/origin.</div></div><div><h3>Results</h3><div>Of the 4186 patients with febrile syndrome, the most frequent diagnosis was malaria (31.0 %), followed by dengue fever (12.0 %) and nonspecific fever of less than three weeks’ duration (11.6 %). Malaria predominated in people coming from sub-Saharan Africa (58.4 %), while dengue fever was more common in the rest of the regions (19.0 % in South America, 25.0 % in Central America and the Caribbean, 34.2 % in Southeast Asia, and 18.1 % in South-Central Asia). By type of traveller, tuberculosis was more frequent in migrants, malaria in VFRs, and dengue and other arboviral infections in travellers and VFRs.</div></div><div><h3>Conclusions</h3><div>Geographical area of travel and type of traveller are the main determinants of imported fever aetiology. Malaria remains the most common cause of febrile syndrome, especially in VFRs from sub-Saharan Africa, while dengue fever prevails in the other tropical regions.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102833"},"PeriodicalIF":6.3,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HKU5-CoV-2: A silent threat looming in bats HKU5-CoV-2:蝙蝠的无声威胁
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-13 DOI: 10.1016/j.tmaid.2025.102838
Shriyansh Srivastava , Dheeraj Sharma , Sathvik Belagodu Sridhar , Sachin Kumar , Rakesh Sahu , Sumel Ashique , Aroop Mohanty , Sanjit Sah , Vini Mehta , Rachana Mehta , Vasso Apostolopoulos
{"title":"HKU5-CoV-2: A silent threat looming in bats","authors":"Shriyansh Srivastava ,&nbsp;Dheeraj Sharma ,&nbsp;Sathvik Belagodu Sridhar ,&nbsp;Sachin Kumar ,&nbsp;Rakesh Sahu ,&nbsp;Sumel Ashique ,&nbsp;Aroop Mohanty ,&nbsp;Sanjit Sah ,&nbsp;Vini Mehta ,&nbsp;Rachana Mehta ,&nbsp;Vasso Apostolopoulos","doi":"10.1016/j.tmaid.2025.102838","DOIUrl":"10.1016/j.tmaid.2025.102838","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102838"},"PeriodicalIF":6.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modelling international travel as risk of acquiring Dientamoeba fragilis: Comparison to Giardia duodenalis data 模拟国际旅行感染脆弱地阿米巴的风险:与十二指肠贾第鞭毛虫数据的比较。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-13 DOI: 10.1016/j.tmaid.2025.102836
Jukka-Pekka Pietilä , Tuuve A Häkkinen , Jukka Ollgren , Anu Kantele
{"title":"Modelling international travel as risk of acquiring Dientamoeba fragilis: Comparison to Giardia duodenalis data","authors":"Jukka-Pekka Pietilä ,&nbsp;Tuuve A Häkkinen ,&nbsp;Jukka Ollgren ,&nbsp;Anu Kantele","doi":"10.1016/j.tmaid.2025.102836","DOIUrl":"10.1016/j.tmaid.2025.102836","url":null,"abstract":"<div><h3>Background</h3><div>The intestinal parasite <em>Dientamoeba fragilis</em> (DF) is spread worldwide and can cause prolonged gastrointestinal symptoms, yet its link to international travel has been scarcely studied. To explore this connection, we examined the association between DF cases and international travel history by destination, comparing the findings to data on <em>Giardia duodenalis</em> (GD)<em>,</em> a common travel-acquired intestinal parasite.</div></div><div><h3>Methods</h3><div>We analysed clinical data from patients with DF or GD infection in the Helsinki Metropolitan Area, categorizing the patients as travellers and non-travellers on the basis of their travel history. To assess acquisition risk by destination, we devised a DF/GD risk score (RS) relating case numbers to travel volumes as denominators in each destination, with travel data retrieved from the Official Statistics of Finland (OSF).</div></div><div><h3>Results</h3><div>Travel history was reported less frequently by patients with DF (30 %) than GD (60 %). DF had the highest RSs for Africa (41.3), followed by Asia and Oceania (17.9) and the Americas (11.5). The respective GD RSs were 32.8, 25.4, and 11.9. The lowest RSs for both parasites were recorded for Eastern and Western Europe, Russia and the Baltic countries, and Scandinavia. For Asia and Oceania, the GD RS exceeded that of DF; for the other sites, DF had higher RSs than GD.</div></div><div><h3>Conclusions</h3><div><em>Dientamoeba fragilis</em> appears to be transmitted both domestically and internationally. Although the overall acquisition risk appears low, for both <em>Dientamoeba fragilis</em> and <em>Giardia duodenalis</em>, the highest RSs are linked to visits to (sub)tropical regions, with subregional differences between the two parasites.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102836"},"PeriodicalIF":6.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbaric oxygen treatment for chronic insomnia at high altitude: A prospective, randomized, open-label, parallel-group trial 高压氧治疗高原慢性失眠:一项前瞻性、随机、开放标签、平行组试验。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2025-03-13 DOI: 10.1016/j.tmaid.2025.102834
Bin Sun , Jinli He , Haibo Chen , Wenming Zeng , Tingting Tian , Mirebankez Abay , Shizhu Bian , Junyong Zhao , Xia Jin , Xiaofang Tan , Chaoan Zhu , Dan Li , Wenqi Zhou , Yuanlong Zhang , Jun Shang , Jiwei Duan , Zhiming Zhao , Tao Wang , Fan Yang , Chuan Liu , Zhexue Qin
{"title":"Hyperbaric oxygen treatment for chronic insomnia at high altitude: A prospective, randomized, open-label, parallel-group trial","authors":"Bin Sun ,&nbsp;Jinli He ,&nbsp;Haibo Chen ,&nbsp;Wenming Zeng ,&nbsp;Tingting Tian ,&nbsp;Mirebankez Abay ,&nbsp;Shizhu Bian ,&nbsp;Junyong Zhao ,&nbsp;Xia Jin ,&nbsp;Xiaofang Tan ,&nbsp;Chaoan Zhu ,&nbsp;Dan Li ,&nbsp;Wenqi Zhou ,&nbsp;Yuanlong Zhang ,&nbsp;Jun Shang ,&nbsp;Jiwei Duan ,&nbsp;Zhiming Zhao ,&nbsp;Tao Wang ,&nbsp;Fan Yang ,&nbsp;Chuan Liu ,&nbsp;Zhexue Qin","doi":"10.1016/j.tmaid.2025.102834","DOIUrl":"10.1016/j.tmaid.2025.102834","url":null,"abstract":"<div><h3>Background</h3><div>Hyperbaric oxygen (HBO) has been proposed to be effective for treating chronic insomnia at high altitudes.</div></div><div><h3>Methods</h3><div>Patients suffering from chronic insomnia at high altitude were randomly assigned at a 1:1 ratio to either the hyperbaric oxygen (HBO) treatment group or the control group for a 10-day procedure. The primary outcome was insomnia status, which was assessed via the Pittsburgh Sleep Quality Index (PSQI) and the Insomnia Severity Index (ISI). The secondary outcomes included stratified comparisons of changes in the PSQI score and ISI score, Fatigue Severity Scale (FSS) score and Hospital Anxiety and Depression Scale (HADS) score. Analyses were performed for multiple comparisons for the primary outcomes at 2-sided 0.05 significance levels with Bonferroni corrections.</div></div><div><h3>Results</h3><div>A total of 80 patients were randomized in this study, and the median age was 25.0 years (IQR, 21.25–29.75). For the primary outcome of sleep quality, the PSQI score after treatment was significantly lower in the HBO group than in the control group (4.6 ± 3.15 vs. 9.1 ± 4.02; adjusted mean difference [aMD] −3.96 [-5.26 to −2.66], <em>p</em> &lt; 0.0001). The ISI was also significantly lower in the HBO group than in the control group (5.0 ± 4.09 vs. 9.8 ± 6.47; aMD −4.10 [95 % CI, −5.68 to −2.51], <em>p</em> &lt; 0.0001). For the secondary outcomes, the HBO group showed improvements in terms of fatigue, anxiety, and depression. No serious adverse events were reported in either group.</div></div><div><h3>Conclusion</h3><div>HBO is an efficacious and safe treatment for chronic insomnia at high altitude.</div></div><div><h3>Trial registration</h3><div>ChiCTR2100046917.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102834"},"PeriodicalIF":6.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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