Travel Medicine and Infectious Disease最新文献

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Coordinated public health actions following the identification of a measles case arriving on an international flight, Spain: December 2022–January 2023 西班牙,国际航班上发现麻疹病例后的公共卫生协调行动:2022 年 12 月至 2023 年 1 月。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-10-05 DOI: 10.1016/j.tmaid.2024.102768
Noemí López-Perea , Silvia Rivera Ariza , María Magdalena Salom Castell , Conchita Izquierdo Gómez , Montserrat Guillaumes , Aurora Fernández-García , Juan E. Echevarría , María Mar Mosquera , Lourdes Oliva Íñiguez , Ana Delia Cebollada Gracia , Virtudes Gallardo García , María Victoria García Rivera , Bernardo Guzmán Herrador , Isabel Huertas-Zarco , María del Carmen Pacheco Martínez , Inmaculada Rodero Garduño , Oscar Paz Montero , Berta Suárez Rodríguez , Josefa Masa-Calles
{"title":"Coordinated public health actions following the identification of a measles case arriving on an international flight, Spain: December 2022–January 2023","authors":"Noemí López-Perea ,&nbsp;Silvia Rivera Ariza ,&nbsp;María Magdalena Salom Castell ,&nbsp;Conchita Izquierdo Gómez ,&nbsp;Montserrat Guillaumes ,&nbsp;Aurora Fernández-García ,&nbsp;Juan E. Echevarría ,&nbsp;María Mar Mosquera ,&nbsp;Lourdes Oliva Íñiguez ,&nbsp;Ana Delia Cebollada Gracia ,&nbsp;Virtudes Gallardo García ,&nbsp;María Victoria García Rivera ,&nbsp;Bernardo Guzmán Herrador ,&nbsp;Isabel Huertas-Zarco ,&nbsp;María del Carmen Pacheco Martínez ,&nbsp;Inmaculada Rodero Garduño ,&nbsp;Oscar Paz Montero ,&nbsp;Berta Suárez Rodríguez ,&nbsp;Josefa Masa-Calles","doi":"10.1016/j.tmaid.2024.102768","DOIUrl":"10.1016/j.tmaid.2024.102768","url":null,"abstract":"<div><div>Contact tracing of individual exposed to any infectious measles case deserves special attention when in the country the disease is mostly imported. We present the coordinated public health actions triggered after reporting a suspected measles case in an aircraft. Spanish public health authorities and airlines responded promptly to allow a rapid contact tracing. Even one secondary measles case was reported no further transmission was identified, revealing that giving PEP and appropriate information help to avoid transmission and to maintain measles elimination in Spain.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102768"},"PeriodicalIF":6.3,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the journey towards rabies vaccination for travellers: Results of a cross-sectional survey with patients and providers in the US, Germany, Sweden, and Switzerland 了解旅行者接种狂犬病疫苗的过程:对美国、德国、瑞典和瑞士的患者和医疗服务提供者进行横断面调查的结果。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-10-04 DOI: 10.1016/j.tmaid.2024.102767
Jennifer Cummins , Florian Lienert , Annabel Su , Elaine Melander , Rebecca L. West , Fernanda Salgado
{"title":"Understanding the journey towards rabies vaccination for travellers: Results of a cross-sectional survey with patients and providers in the US, Germany, Sweden, and Switzerland","authors":"Jennifer Cummins ,&nbsp;Florian Lienert ,&nbsp;Annabel Su ,&nbsp;Elaine Melander ,&nbsp;Rebecca L. West ,&nbsp;Fernanda Salgado","doi":"10.1016/j.tmaid.2024.102767","DOIUrl":"10.1016/j.tmaid.2024.102767","url":null,"abstract":"<div><h3>Background</h3><div>Although cases of rabies in international travellers are uncommon, they are a fatal risk which can be alleviated through vaccination prior to travel. As international travel recovers post-COVID, it is vital that travellers are made aware of the risk of rabies when travelling to endemic countries and supported to receive the vaccine when eligible.</div></div><div><h3>Methods</h3><div>Online surveys were conducted in the US, Germany, Sweden and Switzerland between November 2022–January 2023 with both patients and healthcare providers (HCPs). Eligibility criteria for patients included those eligible for rabies pre-exposure prophylaxis (PrEP) due to travel location and activity; HCPs had to be providers of travel vaccinations. In both surveys, questions were asked about discussion of rabies vaccination, decision of whether to administer a rabies vaccine, recommendation to get the rabies vaccine, and final decision to get a vaccine.</div></div><div><h3>Results</h3><div>The final patient sample included n = 1557 patients who were eligible for rabies pre-exposure prophylaxis (US n = 504, Germany n = 353, Sweden n = 350, Switzerland n = 350) and n = 219 HCPs (US n = 75, Germany n = 75, Sweden n = 32, Switzerland n = 37). Although all patients in the sample were eligible for rabies vaccination, only 15 % felt they were at risk of getting rabies, and only 18 % received the rabies vaccine before their trip. HCPs reported discussing PrEP and/or PrEP and PEP with 30 % of patients presenting for travel vaccination advice, on average.</div></div><div><h3>Conclusions</h3><div>Awareness and perception of rabies risk, and lack of consistent HCP discussion of the need for rabies PrEP may be major barriers to uptake of the vaccine for patients who are eligible to receive it.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102767"},"PeriodicalIF":6.3,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is it safe to travel? The H5N1 avian flu and the Aesop novel 旅行安全吗?H5N1 禽流感与伊索小说。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-10-03 DOI: 10.1016/j.tmaid.2024.102769
Francesco Branda, Alessandra Ciccozzi, Chiara Romano, Daria Sanna, Massimo Ciccozzi, Fabio Scarpa
{"title":"Is it safe to travel? The H5N1 avian flu and the Aesop novel","authors":"Francesco Branda,&nbsp;Alessandra Ciccozzi,&nbsp;Chiara Romano,&nbsp;Daria Sanna,&nbsp;Massimo Ciccozzi,&nbsp;Fabio Scarpa","doi":"10.1016/j.tmaid.2024.102769","DOIUrl":"10.1016/j.tmaid.2024.102769","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102769"},"PeriodicalIF":6.3,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Travellers with prosthetic limbs: A neglected population 装有假肢的旅行者:一个被忽视的群体。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-10-03 DOI: 10.1016/j.tmaid.2024.102770
Irmgard L. Bauer, Vikranth H. Nagaraja
{"title":"Travellers with prosthetic limbs: A neglected population","authors":"Irmgard L. Bauer,&nbsp;Vikranth H. Nagaraja","doi":"10.1016/j.tmaid.2024.102770","DOIUrl":"10.1016/j.tmaid.2024.102770","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102770"},"PeriodicalIF":6.3,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First imported Clade 1b Mpox case in India: Implications for travel medicine and public health surveillance 印度首例输入性 1b 支原体麻疹病例:对旅行医学和公共卫生监测的影响。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-10-01 DOI: 10.1016/j.tmaid.2024.102766
Sanjit Sah, Yogesh Kumar Dhandh, Rachana Mehta, Mahendra Pratap Singh, Ganesh Bushi, Muhammed Shabil, Kiran Bhopte, Amogh Verma
{"title":"First imported Clade 1b Mpox case in India: Implications for travel medicine and public health surveillance","authors":"Sanjit Sah,&nbsp;Yogesh Kumar Dhandh,&nbsp;Rachana Mehta,&nbsp;Mahendra Pratap Singh,&nbsp;Ganesh Bushi,&nbsp;Muhammed Shabil,&nbsp;Kiran Bhopte,&nbsp;Amogh Verma","doi":"10.1016/j.tmaid.2024.102766","DOIUrl":"10.1016/j.tmaid.2024.102766","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102766"},"PeriodicalIF":6.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142372963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demographic, epidemiological and clinical characteristics of Ukrainian war refugees with HIV infection in the Slovak Republic 斯洛伐克共和国感染艾滋病毒的乌克兰战争难民的人口、流行病学和临床特征。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-09-27 DOI: 10.1016/j.tmaid.2024.102764
Ricardo Massmann , Kristína Doležalová (Mgr) , Lubomír Soják , Olena Samsonová , Danica Valkovičová Staneková , Ondrej Zahornacký , Pavol Jarčuška , Mária Záriš Vachalíková , Diana Vološinová , Ľubica Piesecká , Veronika Vahalová , Katarína Šimeková , Terézia Smiešková , Alexandra Bražinová , Ivy Kigen , Marek Malý , Ladislav Machala
{"title":"Demographic, epidemiological and clinical characteristics of Ukrainian war refugees with HIV infection in the Slovak Republic","authors":"Ricardo Massmann ,&nbsp;Kristína Doležalová (Mgr) ,&nbsp;Lubomír Soják ,&nbsp;Olena Samsonová ,&nbsp;Danica Valkovičová Staneková ,&nbsp;Ondrej Zahornacký ,&nbsp;Pavol Jarčuška ,&nbsp;Mária Záriš Vachalíková ,&nbsp;Diana Vološinová ,&nbsp;Ľubica Piesecká ,&nbsp;Veronika Vahalová ,&nbsp;Katarína Šimeková ,&nbsp;Terézia Smiešková ,&nbsp;Alexandra Bražinová ,&nbsp;Ivy Kigen ,&nbsp;Marek Malý ,&nbsp;Ladislav Machala","doi":"10.1016/j.tmaid.2024.102764","DOIUrl":"10.1016/j.tmaid.2024.102764","url":null,"abstract":"<div><h3>Background</h3><div>The Slovak Republic, an Eastern European country, borders Ukraine, which has one of the highest rates of HIV/AIDS in Europe. This study aims to inform readers about the demographic characteristics of Ukrainian war refugees with HIV/AIDS seeking temporary protection status in Slovakia due to the Russian invasion of February 24, 2022. It focuses on their epidemiology, immunological profiles, co-infections, and treatment.</div></div><div><h3>Design</h3><div>Multicenter, retrospective study between March 1, 2022, and March 31, 2023.</div></div><div><h3>Methods</h3><div>Data were collected from all Ukrainian patients with refugee status living with HIV or newly diagnosed, who presented to any of the five HIV/AIDS centers in Slovakia. Information was obtained through medical interviews, physical examinations, laboratory tests and medical reports from the Ukrainian Ministry of Health.</div></div><div><h3>Results</h3><div>From March 1, 2022, to March 31, 2023, 141 Ukrainian refugees were included, mostly women (56.7 %, n = 80), with a median age of 41 years. The median CD4<sup>+</sup> count was 680 cells/mL; 69.2 % (n = 97) had a viral load below 40 copies/mL. On arrival, 87.8 % (n = 123) were on ART, 90.2 % (n = 111) on dolutegravir. Coinfections included hepatitis C (31 %, n = 41), hepatitis B (12.5 %, n = 17), and tuberculosis (11.3 %, n = 16). Three died from AIDS complications.</div></div><div><h3>Conclusion</h3><div>The study provides a detailed overview of the epidemiological, demographic, immunological, co-infection, and treatment characteristics of Ukrainian PLWHA displaced by the war to the Slovak republic. With the conflict ongoing, it is necessary to be prepared for more refugees in the coming months.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102764"},"PeriodicalIF":6.3,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Locally acquired cutaneous larva migrans in Ontario? 安大略省本地获得性皮肤幼虫移行症?
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-09-26 DOI: 10.1016/j.tmaid.2024.102765
Manreet Dhaliwal, Isaac I. Bogoch
{"title":"Locally acquired cutaneous larva migrans in Ontario?","authors":"Manreet Dhaliwal,&nbsp;Isaac I. Bogoch","doi":"10.1016/j.tmaid.2024.102765","DOIUrl":"10.1016/j.tmaid.2024.102765","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102765"},"PeriodicalIF":6.3,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Malaria vaccine a boon to Endemic regions - Doubling efficacy rates, at lower cost 新型疟疾疫苗为疟疾流行地区带来福音--以更低的成本将有效率提高一倍。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-09-26 DOI: 10.1016/j.tmaid.2024.102763
Amrit Kahlon, Steven Lippmann, Rachana Mehta, Vini Mehta, Jack Feehan, Vasso Apostolopoulos , Ranjit Sah
{"title":"New Malaria vaccine a boon to Endemic regions - Doubling efficacy rates, at lower cost","authors":"Amrit Kahlon,&nbsp;Steven Lippmann,&nbsp;Rachana Mehta,&nbsp;Vini Mehta,&nbsp;Jack Feehan,&nbsp;Vasso Apostolopoulos ,&nbsp;Ranjit Sah","doi":"10.1016/j.tmaid.2024.102763","DOIUrl":"10.1016/j.tmaid.2024.102763","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102763"},"PeriodicalIF":6.3,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rabies post-exposure prophylaxis: A retrospective analysis of timing of initiation and antibody responses in a Belgian cohort 狂犬病暴露后预防:对比利时队列中的启动时间和抗体反应的回顾性分析。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-09-19 DOI: 10.1016/j.tmaid.2024.102761
Matilde Hens , Steven Declercq , Nicole Berens-Riha , Ula Maniewski , Caroline Theunissen , Steven Van Den Broucke , Felix De Bièvre , Isabel Brosius , Laurens Liesenborghs , Christophe Van Dijck , Christophe Burm , Inne Nauwelaers , Katleen Balliauw , Benjamin J. Visser , Emmanuel Bottieau , Patrick Soentjens
{"title":"Rabies post-exposure prophylaxis: A retrospective analysis of timing of initiation and antibody responses in a Belgian cohort","authors":"Matilde Hens ,&nbsp;Steven Declercq ,&nbsp;Nicole Berens-Riha ,&nbsp;Ula Maniewski ,&nbsp;Caroline Theunissen ,&nbsp;Steven Van Den Broucke ,&nbsp;Felix De Bièvre ,&nbsp;Isabel Brosius ,&nbsp;Laurens Liesenborghs ,&nbsp;Christophe Van Dijck ,&nbsp;Christophe Burm ,&nbsp;Inne Nauwelaers ,&nbsp;Katleen Balliauw ,&nbsp;Benjamin J. Visser ,&nbsp;Emmanuel Bottieau ,&nbsp;Patrick Soentjens","doi":"10.1016/j.tmaid.2024.102761","DOIUrl":"10.1016/j.tmaid.2024.102761","url":null,"abstract":"<div><h3>Background</h3><div>We aimed to determine the timeliness of rabies post-exposure prophylaxis (PEP) and the proportion of individuals with an adequate antibody response post-PEP among those attending the Belgian national reference center.</div></div><div><h3>Methods</h3><div>Retrospective analysis of patient records who attended our center from 2018 to 2023. Delay was defined as rabies immunoglobulin (RIG) and vaccine initiation beyond 2 calendar days after exposure. Antibodies were measured by rapid fluorescent focus inhibition test (RFFIT) after PEP in high-risk exposures. A titer ≥0.5 IU/ml was considered adequate.</div></div><div><h3>Results</h3><div>We reviewed 317 patient records. Among individuals with inland exposure (n = 103), 85 % timely received PEP. Among travelers exposed abroad (n = 214), administration of RIG and vaccine initiation were timely in 30 % and 50 % of cases, respectively. An adequate antibody response was detected in 99.5 % (195/196) individuals.</div></div><div><h3>Conclusion</h3><div>Substantial PEP delays among travelers were observed. The robust antibody responses suggest that routine serological follow-up is not necessary for all patients.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102761"},"PeriodicalIF":6.3,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000784/pdfft?md5=f19e91b9c75bfe6b45881439671e8a65&pid=1-s2.0-S1477893924000784-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dengue fever as autochthonous infectious disease in Italy: Epidemiological, clinical and virological characteristics 登革热作为意大利本土传染病:流行病学、临床和病毒学特征。
IF 6.3 3区 医学
Travel Medicine and Infectious Disease Pub Date : 2024-09-19 DOI: 10.1016/j.tmaid.2024.102762
Serena Vita , Eleonora Lalle , Priscilla Caputi, Francesca Faraglia, Alessandra D'Abramo, Licia Bordi, Gabriella De Carli, Giuseppe Sberna, Maria Letizia Giancola, Gaetano Maffongelli, Cosmina Mija, Andrea Antinori, Stefania Cicalini, Fabrizio Maggi, Enrico Girardi, Francesco Vairo, Emanuele Nicastri
{"title":"Dengue fever as autochthonous infectious disease in Italy: Epidemiological, clinical and virological characteristics","authors":"Serena Vita ,&nbsp;Eleonora Lalle ,&nbsp;Priscilla Caputi,&nbsp;Francesca Faraglia,&nbsp;Alessandra D'Abramo,&nbsp;Licia Bordi,&nbsp;Gabriella De Carli,&nbsp;Giuseppe Sberna,&nbsp;Maria Letizia Giancola,&nbsp;Gaetano Maffongelli,&nbsp;Cosmina Mija,&nbsp;Andrea Antinori,&nbsp;Stefania Cicalini,&nbsp;Fabrizio Maggi,&nbsp;Enrico Girardi,&nbsp;Francesco Vairo,&nbsp;Emanuele Nicastri","doi":"10.1016/j.tmaid.2024.102762","DOIUrl":"10.1016/j.tmaid.2024.102762","url":null,"abstract":"<div><h3>Background</h3><div>Since August to November 2023, 82 cases of autochthonous or non-travel related Dengue virus (DENV) infection have been reported in Italy, highlighting a concerning trend of local transmission. We describe the clinical and laboratory findings of 10 autochthonous DENV in the metropolitan area of Rome admitted to the Lazzaro Spallanzani National Institute for Infectious Diseases.</div></div><div><h3>Method and results</h3><div>Ten patients (3 males, 7 females; median age: 51) with classic dengue fever symptoms were admitted between August and November 2023. Laboratory tests confirmed dengue infection through DENV non-structural protein 1 and/or immunoglobulins (IgM/IgG) positive tests, moreover leukopenia, thrombocytopenia, elevated transaminases were detected. A subset of patients underwent extensive biological sampling, including real-time RT-PCR and immunofluorescence, to monitor DENV-RNA and antibody levels over 30 days. DENV-1 was detected in 8 patients and DENV-3 in 2. Upon admission specific IgM antibodies were found in 7 patients while IgG antibodies in 4 patients. DENV RNA was consistently detected in blood within the first 8 days but was less common in saliva and urine. No DENV RNA was detected after day 24.</div></div><div><h3>Conclusion</h3><div>These findings contribute to the understanding of the clinical course of DENV infection in a non-endemic setting as integrated epidemiological and clinical model to increase syndromic surveillance and timely diagnosis of DENV infections.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102762"},"PeriodicalIF":6.3,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000796/pdfft?md5=406a09249a1a59ee06646985a531d633&pid=1-s2.0-S1477893924000796-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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