Travel Medicine and Infectious Disease最新文献

{"title":"Changes in body composition during acute exposure to high altitude is related to acute mountain sickness.","authors":"Simin Zhou, Huaping Dong, Pei Huang, Yaling Li, Zhifeng Zhong, Heng Xiao, Jiaxin Xie, Yu Wu, Peng Li","doi":"10.1016/j.tmaid.2025.102815","DOIUrl":"https://doi.org/10.1016/j.tmaid.2025.102815","url":null,"abstract":"<p><strong>Background: </strong>Acute hypoxia exposure leads to a high incidence of acute mountain sickness (AMS) and changes in body composition, while the relationship between body composition and AMS remains unclear. We designed this study to detect the body composition and discern its relationship with AMS.</p><p><strong>Methods: </strong>Eighty-one subjects were transported from the plain (300 m) to the plateau (3600 m). The body weight and body composition were measured in the plain and at the plateau. The occurrence of AMS was investigated by using the Lake Louise Scoring (LLS) system for six consecutive days. Then, the relationship between body composition and AMS was further analyzed.</p><p><strong>Results: </strong>The body weight, fat-free mass (FFM), total body water (TBW), intracellular water (ICW), extracellular water (ECW) and segmental lean mass decreased significantly with the prolonged stay at the plateau. Compared with those in the plain, FM increased significantly at the plateau, and the mineral increased significantly on the third day while decreasing significantly on the sixth day. The daily incidence of AMS during the first 6 days at the plateau was 23.46%, 7.41%, 2.47%, 2.47%, 1.23%, and 2.47%, respectively. Correlation analysis showed that the decline of FFM, TBW, and ECW was positively correlated with the LLS score. Among the AMS relevant symptoms, only fatigue was positively correlated with the decline of FFM, TBW, ICW, and ECW.</p><p><strong>Conclusions: </strong>Significant changes of body composition were observed in the early stage after ascent to plateau. The decline of FFM, TBW, and ECW might be related to the severity of AMS, and fatigue was positively correlated with the decline of FFM, TBW, ICW and ECW.</p>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":" ","pages":"102815"},"PeriodicalIF":6.3,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The next arbovirus epidemic in Latin America and beyond: A question of when, not if – Mayaro, Oropouche, Usutu or Disease X?","authors":"Salim Mattar ,&nbsp;Yesica López ,&nbsp;German Arrieta ,&nbsp;Ameth Salim Mattar ,&nbsp;Antonio Carlos Bandeira ,&nbsp;Alberto Paniz-Mondolfi ,&nbsp;Jan Felix Drexler ,&nbsp;Alfonso J. Rodriguez-Morales","doi":"10.1016/j.tmaid.2025.102818","DOIUrl":"10.1016/j.tmaid.2025.102818","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102818"},"PeriodicalIF":6.3,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commemorating Carlos Chagas: A legacy of comprehensive disease discovery and public health advancement","authors":"Jaime David Acosta-España ,&nbsp;Jenny Belén Altamirano-Jara ,&nbsp;Hugo Monteiro Faver ,&nbsp;Thiago Areas Lisboa Netto","doi":"10.1016/j.tmaid.2025.102816","DOIUrl":"10.1016/j.tmaid.2025.102816","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102816"},"PeriodicalIF":6.3,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rabies in humans: A treatment approach","authors":"Cornelis A. De Pijper ,&nbsp;Pieter P.A.M. van Thiel ,&nbsp;Diederik van de Beek ,&nbsp;Matthijs C. Brouwer ,&nbsp;Eleonora Aronica ,&nbsp;Nicole P. Juffermans ,&nbsp;Ron A.A. Mathôt ,&nbsp;Corine H. GeurtsvanKessel ,&nbsp;Janke Schinkel ,&nbsp;Menno D. de Jong ,&nbsp;Martin P. Grobusch ,&nbsp;Abraham Goorhuis","doi":"10.1016/j.tmaid.2025.102813","DOIUrl":"10.1016/j.tmaid.2025.102813","url":null,"abstract":"<div><h3>Background</h3><div>Only few rabies survivors have been described in the medical literature, of whom most suffered severe neurological sequelae. Published treatment protocols have not been applied successfully. Yet, experimental treatments may be of benefit when factors associated with survival are present. Here, we describe two patients who were hospitalised at Amsterdam UMC with clinical rabies and who died despite experimental treatments.</div></div><div><h3>Methods</h3><div>We describe the clinical course and medical decisions in the treatment of two rabies patients at our hospital and compared this approach with published data on the treatment of clinical rabies, depending on the presence or absence of prognostic factors associated with survival, and regarded this information in the context of clinical practice.</div></div><div><h3>Results</h3><div>The most important factor associated with survival - the presence of high antibody titres in serum or cerebrospinal fluid (CSF) at the time of diagnosis - was not present in either of the two cases at our hospital. In addition to supportive treatment, both of our patients were treated unsuccesfully with a novel treatment approach with intrathecal and intravenous monoclonal rabies antibodies, which barely increased serum and CSF antibody levels.</div></div><div><h3>Conclusions</h3><div>Higher-dosed treatments with monoclonal antibodies in serum may be needed to yield an effect. Any experimental treatment may be most promising in patients who have other factors associated with survival. In the absence of these, initiation of palliative care still seems to remain the most rational strategy.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102813"},"PeriodicalIF":6.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of imported Plasmodium malariae infection after treated Plasmodium falciparum malaria: Possible explanations and a review of the literature","authors":"R. Paggi ,&nbsp;A. Lanari ,&nbsp;C. Malcontenti ,&nbsp;D. Boccolini ,&nbsp;A. Aiello ,&nbsp;M. L'Episcopia ,&nbsp;C. Severini ,&nbsp;C. Nencioni ,&nbsp;M. Lapini ,&nbsp;G.M. Rossolini ,&nbsp;J. Richter ,&nbsp;A. Bartoloni ,&nbsp;L. Zammarchi","doi":"10.1016/j.tmaid.2025.102810","DOIUrl":"10.1016/j.tmaid.2025.102810","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102810"},"PeriodicalIF":6.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crimean-Congo haemorrhagic fever virus screening among African individuals in Spain: Lessons to learn","authors":"Helena Miriam Lorenzo Juanes ,&nbsp;Amparo López-Bernus ,&nbsp;Belen Vicente ,&nbsp;Montserrat Alonso-Sardón ,&nbsp;Beatriz Rodríguez Alonso ,&nbsp;Josue Pendones Ulerio ,&nbsp;Pedro Fernandez Soto ,&nbsp;Juan Luis Muñoz Bellido ,&nbsp;Antonio Muro ,&nbsp;Moncef Belhassen-García","doi":"10.1016/j.tmaid.2025.102814","DOIUrl":"10.1016/j.tmaid.2025.102814","url":null,"abstract":"<div><h3>Background</h3><div>Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne viral disease. CCHF is an emerging infectious disease given the expanding distribution of its main vector. This study aimed to evaluate the importance of CCHFV infection in migrants from Africa who attended a tertiary health care centre in Spain.</div></div><div><h3>Methodology</h3><div>A seroepidemiological study was conducted among African patients referred to the University Hospital of Salamanca, Spain. Patients were retrospectively recruited from 2005 to 2023.</div></div><div><h3>Principal findings</h3><div>We screened 485 serum samples, with a mean (±SD) age of 17 years (±9.9). Among these individuals, 18 were IgG positive and 9 were IgM positive, resulting in an IgG seroprevalence against CCHFV of 3.71 % and an IgM seroprevalence of 1.85 %. Most IgG-positive samples were collected in 2010 (14/316), representing a seroprevalence of 4.43 %. Forty-seven percent of the immigrant participants were from Equatorial Guinea; thus, the IgG seroprevalence among the Equatorial Guinean immigrant population (13/228) was 5.70 %. All patients were negative according to RT‒PCR.</div></div><div><h3>Conclusions</h3><div>This is the first serosurvey conducted in Spain to suggest possible active circulation of the virus in Africans. Our results suggest the need for more extensive clinical and epidemiological studies in Africans to determine the epidemiology and transmission of CCHFV in Spain and to evaluate the relevance of control measures for clinical interventions in situations with a potential risk of transmission. Although the risk is considered very low in these collectives, clinicians should be alert to the possibility of new CCHF cases, given the high pathogenicity of CCHFV and the risk of transmission.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102814"},"PeriodicalIF":6.3,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences between Influenza H5N1, A/H1N1 2009, and SARS-CoV-2 in a pandemic risk scenario","authors":"Pablo I. Plaza,&nbsp;Sergio A. Lambertucci","doi":"10.1016/j.tmaid.2025.102811","DOIUrl":"10.1016/j.tmaid.2025.102811","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102811"},"PeriodicalIF":6.3,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Travellers’ adherence to atovaquone/proguanil malaria chemoprophylaxis after return from endemic areas","authors":"Jenny Lea Schnyder ,&nbsp;David Cornelis Birkhoff ,&nbsp;Myrthe Celine Jarings ,&nbsp;Sabine Margot Hermans ,&nbsp;Martin Peter Grobusch ,&nbsp;Hanna Katrien de Jong","doi":"10.1016/j.tmaid.2025.102812","DOIUrl":"10.1016/j.tmaid.2025.102812","url":null,"abstract":"<div><h3>Background</h3><div>According to current guidelines, atovaquone/proguanil (AP) malaria chemoprophylaxis is taken once daily during travel, and continued for seven days after return from malaria-endemic areas. However, pharmacokinetic data and studies on drug-sparing AP regimens suggest that AP could possibly be discontinued upon return without loss of protection. Besides being more cost-effective, shorter AP regimens may enhance adherence. We aimed to investigate adherence to the current AP chemoprophylaxis regimen during the seven days post-travel, and travellers’ preferences for potential drug-sparing AP regimens.</div></div><div><h3>Methods</h3><div>In this cross-sectional study, adult travellers, who were prescribed AP chemoprophylaxis during a pre-travel consultation between 01-12-2022 and 01-12-2023 at the Amsterdam UMC travel clinic, were send a post-travel online questionnaire. The primary outcome was the proportion of travellers non-adherent to AP during the seven days post-travel, defined as missing one tablet or more. Secondary outcomes were non-adherence during travel, reasons for non-adherence, and AP regimen preferences.</div></div><div><h3>Results</h3><div>The questionnaire was completed by 62 % (382/614) of contacted travellers. Of the participants, 31 % (117/382) reported non-adherence during the seven days post-travel; during stay this was 16 % (58/382). Frequently reported reasons for non-adherence were: forgetfulness, low self-perceived malaria risk, and adverse effects. An alternative AP regimen discontinuing AP upon return was deemed most appealing and easy to adhere by 73 % (276/376) of participants.</div></div><div><h3>Conclusions</h3><div>Non-adherence was high during the seven days after return. Travellers preferred an alternative AP chemoprophylaxis regimen, allowing them to discontinue upon return. Future research shall be conducted to investigate whether AP could be discontinued upon return.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102812"},"PeriodicalIF":6.3,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leukemoid-like eosinophilia in a splenectomised traveler returning from Brazil","authors":"Anna Barbiero ,&nbsp;Laura Povolo ,&nbsp;Michele Spinicci ,&nbsp;Costanza Fiorelli ,&nbsp;Sara De Chiara ,&nbsp;Alessandro Bartoloni ,&nbsp;Lorenzo Zammarchi","doi":"10.1016/j.tmaid.2025.102809","DOIUrl":"10.1016/j.tmaid.2025.102809","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102809"},"PeriodicalIF":6.3,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The EP3622 clone of CD1a for diagnosing intestinal leishmaniasis in an acquired immunodeficiency syndrome patient in Colombia","authors":"Diego Andrés Rodríguez-Lugo ,&nbsp;Jorge Alfredo Morcillo Muñoz ,&nbsp;Javier Hernández Moreno ,&nbsp;Carolina Moreno Reyes ,&nbsp;Luz Helena Patiño ,&nbsp;David F. Martínez ,&nbsp;Juan Fernando Contreras-Valero ,&nbsp;Juan David Ramírez ,&nbsp;Álvaro A. Faccini-Martínez","doi":"10.1016/j.tmaid.2025.102808","DOIUrl":"10.1016/j.tmaid.2025.102808","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"64 ","pages":"Article 102808"},"PeriodicalIF":6.3,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}