Travel Medicine and Infectious Disease最新文献

{"title":"Etiologies of acute febrile illness among hospitalized patients: A retrospective hospital-based study in Mogadishu, Somalia","authors":"Abyan Hassan Dimbil ,&nbsp;Marian-run Abdiwali Mohamed ,&nbsp;Phimphan Pisutsan ,&nbsp;Tanaya Siripoon ,&nbsp;Thundon Ngamprasertchai ,&nbsp;Saranath Lawpoolsri ,&nbsp;Sophie Schneitler ,&nbsp;Kesinee Chotivanich ,&nbsp;Wirongrong Chierakul ,&nbsp;Watcharapong Piyaphanee ,&nbsp;Wasin Matsee","doi":"10.1016/j.tmaid.2025.102898","DOIUrl":"10.1016/j.tmaid.2025.102898","url":null,"abstract":"<div><h3>Background</h3><div>Acute febrile illness (AFI) is a major cause of hospitalization in tropical regions. While it is often initially diagnosed as malaria in Africa, its specific causes in Somalia remain largely unknown. This study aimed to identify the etiology and clinical outcomes of AFI among hospitalized adults in Mogadishu, Somalia.</div></div><div><h3>Methods</h3><div>Medical records of adult patients presented with fever (≥15 years, temperature ≥37.5 °C) who were hospitalized from January 1, 2021 to 31 December 2023 at Somalia Mogadishu-Turkish Teaching and Research Hospital, Somalia were retrospectively examined. We described the demographic data, clinical characteristics, laboratory parameters, treatment modalities, and outcomes among these patients. Univariate and multivariate analyses were then performed to identify factors associated with severe outcomes.</div></div><div><h3>Results</h3><div>A total of 1648 cases were initially collected. After applying the inclusion criteria and removing duplicates and mislabeled files, 702 cases (42.6 %) were included in the study. Etiologies were identified in 24.2 % of these cases, with the most common being acute hepatitis A (9.5 %) and malaria (7.7 %). Antibiotics were used in 83.3 % of patients. Factors associated with an identified etiology included pre-existing medical conditions, genitourinary involvement, and a shorter fever duration. Overall, 61.4 % of patients recovered, while the mortality rate was 10.5 %, with the highest rate attributed to urinary tract sepsis (2.7 %). Poor outcomes were significantly associated with an elevated white blood cell count, elevated serum creatinine, and advanced age.</div></div><div><h3>Conclusion</h3><div>These findings underscore diagnostic limitations and antimicrobial misuse, emphasizing the need for expanded laboratory capabilities with pathogen-specific testing to better identify AFI in Somalia.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102898"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144970644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First evidence of significant autochthonous transmission of strongyloidiasis in northern Spain: A retrospective study from Asturias, Spain","authors":"Mercedes Rodríguez-Pérez ,&nbsp;Belén Rivaya ,&nbsp;Fernando Vazquez ,&nbsp;José Antonio Boga ,&nbsp;Enrique de Andrés-Galiana ,&nbsp;Rebeca Cabo ,&nbsp;Juan Luis Fernández-Martínez ,&nbsp;Azucena Rodríguez- Guardado","doi":"10.1016/j.tmaid.2025.102900","DOIUrl":"10.1016/j.tmaid.2025.102900","url":null,"abstract":"<div><h3>Background</h3><div>Autochthonous strongyloidiasis in Spain has traditionally been considered a recognized but underdiagnosed condition, primarily affecting individuals in agricultural environments along the Mediterranean coast. We describe the first series of autochthonous strongyloidiasis cases diagnosed in Asturias, a region in northern Spain with no previously documented endemic transmission.</div></div><div><h3>Methods</h3><div>This is a retrospective review of all diagnosed cases of autochthonous strongyloidiasis at the Central University Hospital of Asturias, from 2016 to 2024. Inclusion required no travel history to endemic areas. Clinical records were reviewed for demographic data, symptoms, risk factors, laboratory findings, and treatment outcomes.</div><div>Diagnosis was based on stool microscopy, <em>S. stercoralis</em> IgG serology, and polymerase chain reaction.</div></div><div><h3>Results</h3><div>We identified 33 patients (54.5 % female, mean age 52 ± 20 years). The primary risk factor was residence in a rural area (63.6 %), frequently associated with gardening that was the most common risk factor (57.5 %). Symptoms were reported in 78.7 % of cases, most commonly abdominal pain (46 %) and pruritus (38.4 %). Eosinophilia was present in 33.3 % of cases. Diagnosis relied primarily on serology (71.4 %) and PCR (56.2 %). Stool microscopy detected larvae in only two patients (6 %). Three patients (9.3 %) developed severe forms, including one fatal case.</div></div><div><h3>Conclusions</h3><div>This study provides strong evidence of ongoing autochthonous transmission of <em>Strongyloides stercoralis</em> in northern Spain, affecting a younger and more gender-balanced population than previously described. Recreational rather than occupational exposure was the predominant risk factor. Routine screening should be considered in autochthonous individuals with eosinophilia or prior to immunosuppressive therapy to prevent severe outcomes.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102900"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leishmaniasis in the United Kingdom: Experience of a national multidisciplinary team meeting in a non-endemic setting","authors":"Owain Donnelly ,&nbsp;Rachel Southern-Thomas ,&nbsp;Simran Goyal ,&nbsp;Ciara Mahon ,&nbsp;Adam T. Gray ,&nbsp;Peter L. Chiodini ,&nbsp;June Minton ,&nbsp;Jonathan Joseph ,&nbsp;Sarah Eisen ,&nbsp;Elinor Moore ,&nbsp;Naomi F. Walker ,&nbsp;Mark S. Bailey ,&nbsp;Laura Nabarro ,&nbsp;Stephen L. Walker ,&nbsp;Anna M. Checkley","doi":"10.1016/j.tmaid.2025.102903","DOIUrl":"10.1016/j.tmaid.2025.102903","url":null,"abstract":"<div><h3>Introduction</h3><div>Leishmaniasis is a parasitic disease caused by protozoa of the genus <em>Leishmania</em>. Disease phenotypes are heterogenous, and diagnosis is frequently delayed. Treatment is often challenging, and international guidelines recommend consultation with experts. The UK Leishmaniasis Multidisciplinary Team (UKLMDT) meeting provides an accessible online forum for clinicians to discuss cases of leishmaniasis, facilitating access to expertise and enabling local care for patients where possible.</div></div><div><h3>Methods</h3><div>Three years of UKLMDT discussions, from its inception in November 2021 to October 2024, were reviewed using electronic patient records. An anonymous feedback questionnaire was sent to referrers. Data regarding treatment outcomes for patients discussed up to June 2024 were gathered using a separate questionnaire completed by their responsible clinician.</div></div><div><h3>Results</h3><div>The UKLMDT contributed to 139 patient discussions involving 80 patients over in total over the study period. Just over half of individuals (45/80; 56.2 %) had cutaneous leishmaniasis, a quarter had visceral leishmaniasis (20/80; 25 %) and a tenth had mucosal leishmaniasis (8/80; 10 %). Seven patients (8.8 %) were found not to have leishmaniasis. In total, 24/80 (30 %) of patients were immunocompromised, but only in four cases (5 %) was HIV the cause of immunosuppression. All visceral leishmaniasis cases were acquired in Europe, and the majority acquired their disease in Spain. <em>Leishmania donovani</em> complex was the commonest causative agent overall, including in visceral and mucosal disease, whereas <em>Leishmania Viannia</em> subgenus was commonest in cutaneous leishmaniasis. Patients with mucosal or visceral leishmaniasis were more frequently immunosuppressed than those with cutaneous leishmaniasis. Outcomes and feedback on the UKLMDT were generally positive.</div></div><div><h3>Discussion</h3><div>The experience of the UKLMDT specialist forum provides insight into leishmaniasis in the UK, a non-endemic setting. Key findings include that southern Europe is the primary destination where UK-based leishmaniasis is acquired, and that <em>Leishmania donovani</em> complex (most likely <em>Leishmania infantum</em>) in immunosuppressed hosts is an important cause of mucosal leishmaniasis in Europe. The UKLMDT offers equitable access to expertise for a rare disease in the UK, as well as serving as a model for national provision of multidisciplinary advice for other rare diseases.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102903"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective efficacy of skin-applied arthropod repellents against Chrysops bites in a Loa loa hyperendemic region in Gabon: A placebo-controlled randomized clinical trial of DEET, icaridin, citriodiol, and IR3535","authors":"Ange G. Doumba Ndalembouly ,&nbsp;Stravensky T. Boussougou-Sambe ,&nbsp;Barclaye Ngossanga ,&nbsp;Ynous Djida ,&nbsp;Jacob Werner ,&nbsp;Rella Zoleko Manego ,&nbsp;Roland C. Zinga Koumba ,&nbsp;Rodrigue Mintsa ,&nbsp;Ayôla A. Adegnika ,&nbsp;Albert Eisenbarth ,&nbsp;Michael Ramharter","doi":"10.1016/j.tmaid.2025.102899","DOIUrl":"10.1016/j.tmaid.2025.102899","url":null,"abstract":"<div><h3>Background</h3><div><em>Loa loa – a filarial pathogen causing loiasis –</em>is transmitted by deer fly species <em>Chrysops dimidiata</em> and <em>C. silacea</em>. There are no established control tools available to reduce loiasis transmission in endemic regions. Although the use of repellents has been explored against other arthropods, their protective efficacy against <em>Chrysops</em> bites in humans has not yet been systematically evaluated. The aim of this randomized controlled clinical trial was to assess the efficacy of four commercial skin-applied arthropod repellents against <em>Chrysops</em> bites in a hyperendemic region in Gabon.</div></div><div><h3>Methods</h3><div>Volunteers were randomly assigned to apply the skin repellents DEET, icaridin, citriodiol, IR3535 or an inactive control. The primary endpoint was the number of blood meal attempts by <em>Chrysops</em> flies. Secondary outcomes were the frequency and duration of <em>Chrysops</em> landings on clothing and skin. This study is registered with the Pan African Clinical Trials Registry (PACTR202406779622099).</div></div><div><h3>Results</h3><div>Blood meal attempts were significantly reduced by citriodiol (−50 %, p = 0.04) and DEET (−50 %, p &lt; 0.001), but not by icaridin (0 %, p = 0.48) and IR3535 (0 %, p = 0.69). Concordantly, the time spent by the fly on the skin was significantly shortened by citriodiol (−66 %, p = 0.02) and DEET (−46 %, p &lt; 0.001), but not with icaridin (+2 %, p = 0.35) and IR3535 (0 %, p = 0.93). Conversely, the number of <em>Chrysops</em> landings on untreated clothing was not reduced by DEET and icaridin, while citriodiol and IR3535 treated individuals experienced a higher number of landings (p = 0.005 and p = 0.01, respectively).</div></div><div><h3>Conclusions</h3><div>Citriodiol and DEET showed substantial but not complete protective efficacy against the bite of loiasis vectors. Icaridin and IR3535 were ineffective.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102899"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An outbreak of acute pulmonary histoplasmosis after exposure to guano in a hollow tree in Ecuador","authors":"Andrea Giacomelli ,&nbsp;Cristina Gervasoni ,&nbsp;Giacomo Casalini ,&nbsp;Alessandro Torre ,&nbsp;Marco Schiuma ,&nbsp;Sara Lo Menzo ,&nbsp;Monica Brundu ,&nbsp;Maria Mazzitelli ,&nbsp;Samuele Gardin ,&nbsp;Anna Grancini ,&nbsp;L. Joseph Wheat ,&nbsp;Spinello Antinori ,&nbsp;Annamaria Cattelan","doi":"10.1016/j.tmaid.2025.102902","DOIUrl":"10.1016/j.tmaid.2025.102902","url":null,"abstract":"<div><h3>Background</h3><div>Outside of classic endemic areas, histoplasmosis has gained attention due to an increased incidence in immunocompetent travellers, attributable to changes in behaviours during travel.</div></div><div><h3>Methods</h3><div>A cluster of five patients who presented with acute pulmonary histoplasmosis after travelling to the Ecuadorian Amazon Region is described in this article.</div></div><div><h3>Results</h3><div>Five patients (four females and one male), all in their 20s, presented with acute pulmonary histoplasmosis between sixteen and twenty-three days after the potential airborne exposure after travelling to the Ecuadorian Amazon Region. The initial common exposure is presumed to have occurred during activities inside a hollow tree trunk with guano exposure. Initial symptoms included fever and arthro-myalgias in three cases, and gastrointestinal symptoms with asthenia and lymphadenopathy in the other two cases. Symptoms progressed variably within one week to include chest pain, dyspnoea, and night sweats. Serology was negative in 2 patients during the acute phase but subsequently turned positive in all five cases. Chest CT scans performed within one week from symptom onset in all cases revealed multiple bilateral nodules. In three cases, follow-up chest CT scans performed four-six weeks after symptom onset showed the evolution of nodules into cavitations despite treatment with itraconazole.</div></div><div><h3>Conclusions</h3><div>This cluster of histoplasmosis cases highlights the clinical variability associated with this fungal infection. The development of pulmonary cavitation during the acute phase of the disease is an infrequent finding that poses additional clinical challenges and suggests the requirement of rigorous follow-up in individuals with acute histoplasmosis returning from the Amazon region.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102902"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144996485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasmodium vivax microgametes in a Colombian malaria case: A diagnostic challenge","authors":"Diego Andrés Rodríguez Lugo ,&nbsp;Jorge A. Morcillo Muñoz ,&nbsp;Leidy J. Medina-Lozano ,&nbsp;Álvaro A. Faccini-Martínez","doi":"10.1016/j.tmaid.2025.102895","DOIUrl":"10.1016/j.tmaid.2025.102895","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102895"},"PeriodicalIF":4.7,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144903939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary screening of ESBL-producing Escherichia coli and Klebsiella pneumoniae carriage among migrant communities in Klang Valley, Malaysia","authors":"Muhammad Azreen Mat Husin ,&nbsp;Adrian Anthony Peirera ,&nbsp;Thana Seelan ,&nbsp;Ramliza Ramli ,&nbsp;Ilana Lopes Baratella da Cunha Camargo ,&nbsp;Sheila Nathan ,&nbsp;Hui-min Neoh","doi":"10.1016/j.tmaid.2025.102894","DOIUrl":"10.1016/j.tmaid.2025.102894","url":null,"abstract":"<div><div>Economic migrant workers are crucial for a country's development but may also contribute to transboundary transmission of antimicrobial resistance (AMR). This study aimed to investigate the silent carriage of ESBL-producing <em>Escherichia coli</em> (ESBLEC) and <em>Klebsiella pneumoniae</em> (ESBLKP) among economic migrants from Indonesia, Bangladesh and Nepal residing in Klang Valley, Malaysia. Between December 2023 and May 2024, 263 study participants of Indonesian, Bangladeshi, and Nepalese migrant communities were recruited and rectal swabs collected. Swabs were then cultured on CHROMagar™ ESBL; presumptive ESBL-positive strains were confirmed and antimicrobial susceptibility-tested using a VITEK 2 system. ESBL genotyping was also performed on confirmed isolates. A total of 67 and five strains were confirmed as ESBLEC and ESBLKP, respectively. Both ESBLEC and ESBLKP strains showed similar resistance to penicillin and 3rd generation cephalosporins, though more ESBLKP strains were resistant to 4th generation cephalosporins. More ESBLEC strains were resistant to ciprofloxacin. No carbapenem-resistant strains were detected. The <em>bla</em>_CTX-M-1 gene family was predominantly found in ESBLEC strains from all three nationalities, while ESBLKP strains frequently harboured <em>bla</em>_TEM, <em>bla</em>_CTX-M, and <em>bla</em>_SHV genes. The prevalence of ESBL-producing strains was highest among Bangladeshi participants (n = 16, 31.4 %), followed by Indonesians (n = 47, 29.7 %) and Nepalis (n = 9, 19.1 %) working in domestic or manufacturing sectors. These findings highlight the public health risks of high ESBLEC and ESBLKP carriage in healthy migrant workers, which may impact recruitment and retention, leading to labour shortages and higher costs. Screening and increased awareness are crucial to limit the spread of these pathogens.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102894"},"PeriodicalIF":4.7,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144912280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A decade of dengue disease burden in Africa (2013–2023): a systematic review","authors":"Gaspary O. Mwanyika ,&nbsp;Monika Moir ,&nbsp;Abdualmoniem O. Musa ,&nbsp;Jenicca Poongavanan ,&nbsp;Graeme Dor ,&nbsp;Eduan Wilkinson ,&nbsp;Cheryl Baxter ,&nbsp;Tulio de Oliveira ,&nbsp;Houriiyah Tegally","doi":"10.1016/j.tmaid.2025.102897","DOIUrl":"10.1016/j.tmaid.2025.102897","url":null,"abstract":"<div><h3>Background</h3><div>Dengue is a major mosquito-borne disease worldwide. The epidemiological trends of the disease in Africa over the past decade remain unclear. This review aims to provide insight into the epidemiological trends of dengue in Africa from 2013 to 2023.</div></div><div><h3>Methods</h3><div>We systematically searched PubMed/MEDLINE and Scopus for studies published between January 2013 and December 2023. Additionally, we collected official records from the World Health Organization for Africa and African Centre for Disease Control. We included studies that reported dengue cases in humans in Africa and excluded publications prior to 2013, review articles and non-human studies. For specific countries, the suspected cases per 100,000 population and fatality rates were estimated and the trend predicted using a negative binomial model. The statistical analyses and visualisations were performed using R programming.</div></div><div><h3>Results</h3><div>Of the 453 reports screened, 87 from 25 African countries were selected for systematic review. Of which 55.2 % (48/87) were indicator-based, 40.2 % (35/87) research and 4.6 % (4/87) event-based reports. Between 2013 and 2023, approximately 200,000 suspected dengue cases, 90,000 confirmed cases and 900 deaths were reported in Africa. Over 80 % of confirmed cases originated from West Africa, with Burkina Faso reporting over 500 cases per 100,000 population. DENV1 and DENV2 predominated at different times with transmission closely linked to rainy seasons.</div></div><div><h3>Conclusions</h3><div>The rising dengue cases across Africa, highlight the need to strengthen surveillance and implement effective regional-specific interventions against future dengue outbreaks. Further research is necessary to improve our understanding on dengue transmission dynamics and suitability of regions in Africa.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102897"},"PeriodicalIF":4.7,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144906919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climate change and dengue Fever: A 14-year study of mortality trends during 2010–2023 in Indonesia","authors":"Kurnia Ardiansyah Akbar ,&nbsp;Rosa Kumala Fatma ,&nbsp;Fauzi Elamouri ,&nbsp;Jürgen Kurt Rockstroh","doi":"10.1016/j.tmaid.2025.102893","DOIUrl":"10.1016/j.tmaid.2025.102893","url":null,"abstract":"<div><h3>Background</h3><div>Dengue fever remains a critical public health issue in Indonesia, with a significant increase in mortality cases in recent years. As a vector-borne disease, dengue fever is highly influenced by environmental conditions, making it particularly sensitive to the impacts of climate change. Indonesia, being heavily affected by global climate change, faces increasing challenges in managing dengue fever. This study aims to investigate the association between dengue fever mortality and climate variables, specifically annual rainfall, and temperature, in Indonesia from 2010 to 2023.</div></div><div><h3>Methods</h3><div>Secondary data on dengue fever cases from 2010 to 2023 were collected from the Ministry of Health of Indonesia. Data on annual rainfall and annual temperature were obtained from the Indonesia Meteorology, Climatology, and Geophysics Council, with information gathered from 116 stations across Indonesia. Linear regression analysis was used to determine the association between these variables and dengue fever mortality.</div></div><div><h3>Results</h3><div>The analysis revealed a significant association between annual temperature (p = 0.049; R² = 0.212; 95 % CI: 710.85–2.233) and dengue fever mortality. Additionally, annual dengue fever cases were significantly associated with mortality (p &lt; 0.001; R² = 1.075; 95 % CI: 0.007–0.010). However, annual rainfall was not found to be significant in this study.</div></div><div><h3>Conclusion</h3><div>These findings underscore the importance of monitoring climatic changes and their impact on public health, particularly concerning vector-borne diseases. Enhanced surveillance and targeted interventions could mitigate the adverse effects of these climatic variables on dengue fever mortality in Indonesia.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102893"},"PeriodicalIF":4.7,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144889042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latent tuberculosis infection and sexually transmitted diseases in incoming mobility students at the National Autonomous University of Mexico","authors":"Jorge B. Díaz Ramírez ,&nbsp;Luis A. Cortázar Maldonado ,&nbsp;Patricia Bautista-Carbajal ,&nbsp;Miguel L. García-León ,&nbsp;Anna Fomina ,&nbsp;Karen Chavarría-Villafuerte ,&nbsp;José A. Morales-Fernández ,&nbsp;Midori Kato-Maeda ,&nbsp;Rosa M. Wong-Chew","doi":"10.1016/j.tmaid.2025.102891","DOIUrl":"10.1016/j.tmaid.2025.102891","url":null,"abstract":"<div><h3>Background</h3><div>Little is known about latent tuberculosis infection and sexually transmitted diseases in international mobility students, due to the limited number of educational institutions that provide care for these types of health problems. The aim of this study was to determine the prevalence of latent tuberculosis infection and the presence of some sexually transmitted diseases in the population of incoming mobility students of the National Autonomous University of Mexico (UNAM), as well as their socio-demographic, migratory and health characteristics; in order to contribute to the design of strategies for the detection of asymptomatic diseases that may have an impact on the health of this population.</div></div><div><h3>Methods</h3><div>Incoming mobility students of the UNAM were invited to participate in the study, underwent a clinical history and physical examination, and informed consent was requested for the collection of blood to determine the presence of TB and some sexually transmitted diseases. Socio-demographic, migration and health characteristics were recorded.</div></div><div><h3>Results</h3><div>149 incoming mobility students were recruited, with a prevalence of 7.3 % of latent TB. None of the students were positive for HIV and HCV, and only one student was positive for syphilis.</div></div><div><h3>Conclusions</h3><div>The prevalence of latent TB was 7.3 %. LTB and sexually transmitted diseases in high-risk populations, such as international mobility students, was unknown in our country. It is important to continue with research projects aimed at reducing the burden of disease in this population and to promote the development of strategies that inform educational institutions about their presence, control and prevention.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102891"},"PeriodicalIF":4.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144889041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}