Travel Medicine and Infectious Disease最新文献

{"title":"Atypical cutaneous manifestations of leprosy in a non-endemic country: a case report","authors":"Laura Ponzetta ,&nbsp;Serena Vita ,&nbsp;Angela Corpolongo ,&nbsp;Alessandra D'Abramo ,&nbsp;Alessandra Scarabello ,&nbsp;Paola Mencarini ,&nbsp;Raffaella Libertone ,&nbsp;Virginia Di Bari ,&nbsp;Barbara Bartolini ,&nbsp;Antonella Vulcano ,&nbsp;Emanuele Nicastri","doi":"10.1016/j.tmaid.2026.102963","DOIUrl":"10.1016/j.tmaid.2026.102963","url":null,"abstract":"<div><h3>Background</h3><div>Leprosy, caused by <em>Mycobacterium leprae</em>, can pose diagnostic challenges in non-endemic regions because of its low frequency and possible atypical presentations.</div></div><div><h3>Case presentation</h3><div>This case describes the unusual clinical manifestations of leprosy in a 52-year-old Indian woman who immigrated to Italy: she presented with a granulomatous nasal plaque and hypopigmented abdominal lesion, without evidence of sensory loss or peripheral neuropathy. Initial evaluations were inconclusive, causing a significant diagnostic delay. Definitive diagnosis was achieved by molecular test for <em>Mycobacterium leprae</em> from respiratory and skin samples. After 12 months of multidrug therapy, the nasal lesion resolved completely.</div></div><div><h3>Conclusions</h3><div>This case highlights the imperative for health care providers in nonendemic settings to always consider leprosy in the differential diagnosis of chronic dermatologic conditions, especially in individuals with relevant epidemiologic background, even in absence of typical manifestations, emphasizing the need for high clinical suspicion and multidisciplinary collaboration.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102963"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147309968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the COVID-19 pandemic on travel medicine services in Taiwan, 2019–2022","authors":"Szu-Hsuan Huang ,&nbsp;Yung-Ching Lin ,&nbsp;Yi-Li Shih ,&nbsp;Jiun-Shian Kuo ,&nbsp;Li-Li Ho","doi":"10.1016/j.tmaid.2026.102956","DOIUrl":"10.1016/j.tmaid.2026.102956","url":null,"abstract":"<div><h3>Background</h3><div>The COVID-19 pandemic profoundly disrupted international travel and travel medicine services worldwide. Few studies have examined nationwide trends. We analyzed travel clinic visits and travel medicine services in Taiwan across the pandemic to assess its impact and inform future policy and preparedness planning.</div></div><div><h3>Methods</h3><div>This population-based longitudinal study utilized nationwide data from Travel Medicine Contract Hospitals from 2019 to 2022. The number of travel clinic visits, travel vaccinations, and International Certificate of Vaccination or Prophylaxis (ICVP) issuance were compared between 2019 and subsequent years using paired sample t-tests.</div></div><div><h3>Results</h3><div>During 2019–2022, 218,700 travel clinic visits, 92,218 travel vaccine doses, and 162,653 ICVPs were recorded. Clinic visits decreased by 52 % in 2020 but increased by 80 % in 2021 and 143 % in 2022, exceeding pre-pandemic levels. Travel vaccinations decreased by 70 % in 2020, increased by 229 % in 2021, and then decreased slightly by 22 % in 2022. ICVP issuance dropped by 74 % in 2020 but rose more than fivefold by 2022. The surge in travel vaccinations and ICVP issuance in 2021–2022 was mainly attributed to COVID-19 vaccinations and free yellow fever and meningococcal conjugate vaccination campaigns. The most documented vaccine in ICVPs shifted from yellow fever vaccines to COVID-19 vaccines during 2021–2022.</div></div><div><h3>Conclusions</h3><div>The pandemic reshaped Taiwan's travel medicine landscape. Coordinated government-hospital efforts enabled timely vaccine allocation, minimized wastage, and maintained service capacity. These results underscore the need for flexible vaccination strategies and the transition toward digital health documentation for future preparedness.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102956"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review on the epidemiology, diagnostics and management of leishmaniasis recidivans","authors":"Niels Vanden Bossche ,&nbsp;Matthew Willis ,&nbsp;Fabian Schlumberger ,&nbsp;Mourad Mokni ,&nbsp;Anil Fastenau","doi":"10.1016/j.tmaid.2026.102954","DOIUrl":"10.1016/j.tmaid.2026.102954","url":null,"abstract":"<div><h3>Background</h3><div>One of the most severe and least understood forms of cutaneous leishmaniasis (CL) is leishmaniasis recidivans (LR), a chronic variant in which lesions reappear months or years after apparent healing. This review aimed to consolidate fragmented information to clarify LR's epidemiological scope, diagnostic methods, and treatment strategies.</div></div><div><h3>Methods</h3><div>A comprehensive literature search according to PRISMA guidelines was conducted across multiple databases, with the final search completed on November 15, 2025. Risk of bias was assessed using JBI checklists. A study protocol for this review was registered with OSF (10.17605/OSF.IO/6NFT3). Data were synthesized narratively as meta-analysis was not feasible.</div></div><div><h3>Results</h3><div>Forty-three papers were included, thirty-two from the Old World and eleven from the New, representing seventeen countries. LR primarily affected children, and factors such as trauma, immunosuppression, or irregular treatment were stated as triggers. Cases tended to be geographically restricted, with <em>L. tropica</em> most frequently reported. Both the lesion morphology and the latency period varied widely. Microscopy and histology gave poor accuracy, limited by low parasite loads and overlapping diagnoses. Isoenzyme analysis identified distinct LR strains. Pentavalent antimonials (PA) were the main treatment, and combination regimens showed promise in overcoming LR persistence.</div></div><div><h3>Conclusion</h3><div>LR remains modestly recognized, with considerable overlap with classical CL. The evidence points to species-level differences in recurrence, compounded by the role of host factors and parasite diversity. Consistent adherence to therapy is a decisive element in managing LR. Without broader, more systematically coordinated data, both clinical guidance and effective public health strategies will not be possible.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102954"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surveillance-based insights into mosquito-borne disease trends: Implications for public health in Poland and Europe (2018–2024)","authors":"Anna Bogacka ,&nbsp;Ravi Kant ,&nbsp;Maciej Grzybek","doi":"10.1016/j.tmaid.2026.102953","DOIUrl":"10.1016/j.tmaid.2026.102953","url":null,"abstract":"<div><h3>Introduction</h3><div>Mosquito-borne diseases continue to pose a significant global health challenge, driven by environmental, climatic, and socio-demographic factors. This study investigates the epidemiological trends of malaria, dengue fever, chikungunya, and West Nile virus (WNV) in Poland and Europe, from 2018 to 2024, with a focus on regional differences, local transmission, and temporal dynamics.</div></div><div><h3>Material and methods</h3><div>Data were obtained from national and international surveillance systems. Annual case counts for each disease, including autochthonous cases, were analyzed using Poisson regression models, with calendar year as a continuous predictor. Trends were assessed for Poland (2018–2024) and Europe (2018–2023).</div></div><div><h3>Results</h3><div>In Poland, 521 cases were reported across the study period, with a significantly increasing trend in total case counts for malaria, dengue, and chikungunya. WNV showed a non-significant increase. In Europe, a significant reduction in total cases was observed from 2018 to 2023, including declines in malaria, chikungunya, and WNV, while dengue cases showed a modest but significant increase. Analysis of autochthonous cases revealed a significant overall decrease in malaria and WNV, but a significant increase in dengue cases.</div></div><div><h3>Conclusions</h3><div>The results highlight contrasting regional and transmission-specific trends, with increasing incidence in Poland, declining total and local transmission in Europe, and a rise in autochthonous dengue cases. These findings underscore the importance of strengthening surveillance and response strategies tailored to the dynamic patterns of vector-borne diseases.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102953"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145963426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral schistosomiasis masquerading as a CNS malignancy in a sudanese traveler: A diagnostic challenge and review of literature","authors":"Moustafa A. Mansour ,&nbsp;M. Wahid ,&nbsp;Mohamed A.S. El Molla ,&nbsp;Mohamed H. Helmy ,&nbsp;Taha Mohammed Adel ,&nbsp;Hamdi Nabawi Mostafa","doi":"10.1016/j.tmaid.2026.102959","DOIUrl":"10.1016/j.tmaid.2026.102959","url":null,"abstract":"<div><h3>Introduction</h3><div>Cerebral schistosomiasis is a rare condition, typically associated with <em>Schistosoma japonicum</em>. Cerebral involvement by <em>S. mansoni</em> is exceptionally uncommon and diagnostically challenging, often mimicking CNS tumors.</div></div><div><h3>Case presentation</h3><div>A 31-year-old Sudanese male presented with a simple partial seizure. MRI revealed a left cingulate gyrus mass suggestive of malignancy. Stereotactic biopsy showed granulomas with <em>S. mansoni</em> eggs, confirmed by serology despite negative stool studies. The patient received praziquantel 60 mg/kg/day and prednisolone 50 mg/day for two weeks, resulting in full symptomatic resolution and discharge.</div></div><div><h3>Conclusion</h3><div>This case highlights cerebral schistosomiasis as a critical differential diagnosis for mass lesions in patients from endemic regions, emphasizing the need for early biopsy to guide appropriate therapy and avoid unnecessary surgery.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102959"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146207180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food-borne infections originating from Turkey but detected abroad: A historical review and recommendations","authors":"Deniz Güllü ,&nbsp;Yeşim Beşli ,&nbsp;Önder Ergönül","doi":"10.1016/j.tmaid.2026.102957","DOIUrl":"10.1016/j.tmaid.2026.102957","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102957"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146047138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zika virus infection in a German traveller to the Maldives, August 2025","authors":"Hans Martin Orth ,&nbsp;David Meierkord ,&nbsp;Martha Charlotte Holtfreter ,&nbsp;Tom Luedde ,&nbsp;Jonas Schmidt-Chanasit ,&nbsp;Torsten Feldt","doi":"10.1016/j.tmaid.2026.102960","DOIUrl":"10.1016/j.tmaid.2026.102960","url":null,"abstract":"<div><h3>Background</h3><div>Zika virus (ZIKV) is a neurotropic flavivirus associated with generally mild disease but the risk of congenital abnormalities when contracted during pregnancy. Reports from the Maldives are rare.</div></div><div><h3>Methods</h3><div>We describe a ZIKV infection in a traveller returning from the Maldives in August 2025, including clinical findings and molecular diagnostics with metagenomic sequencing and phylogenetic analysis.</div></div><div><h3>Results</h3><div>ZIKV ribonucleic acid was detected by reverse transcription polymerase chain reaction, and sequencing identified the ZIKV Asian lineage. However, the limited sequence length precluded precise phylogenetic placement.</div></div><div><h3>Conclusion</h3><div>This case underlines the ongoing risk of ZIKV transmission in areas where compatible arthropod vectors are present. Since there is no systematic surveillance in the Maldives, the detection of ZIKV infections in returning travellers is becoming increasingly important for assessing the epidemiological situation.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102960"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From local burden to global threat: Neglected tropical diseases in an era of climate change and human mobility","authors":"Francisco Javier Membrillo ,&nbsp;Juan-Carlos Navarro ,&nbsp;Diana Marcela Pava-Garzón ,&nbsp;Jill Weatherhead ,&nbsp;José A. Suárez ,&nbsp;Alfonso J. Rodriguez-Morales","doi":"10.1016/j.tmaid.2026.102958","DOIUrl":"10.1016/j.tmaid.2026.102958","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102958"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146087290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imported Strongyloides stercoralis infections in Germany: descriptive study of cases over 5 years in a referral center in Berlin","authors":"Antonio Seigerschmidt ,&nbsp;Maria Cristina Moreno-del Castillo ,&nbsp;Gabriela Equihua Martinez ,&nbsp;Paul Pitzinger ,&nbsp;Janina Hammer ,&nbsp;Susanne Georgi ,&nbsp;Michael Nürnberg ,&nbsp;Julian Bernhard ,&nbsp;Franziska Olgemöller ,&nbsp;Beate Kampmann ,&nbsp;Frank P. Mockenhaupt ,&nbsp;Thomas Weitzel ,&nbsp;Andreas K. Lindner","doi":"10.1016/j.tmaid.2026.102952","DOIUrl":"10.1016/j.tmaid.2026.102952","url":null,"abstract":"<div><h3>Background</h3><div><em>Strongyloides stercoralis</em> is a widespread helminth in tropical and subtropical regions, which can persist in humans for life through autoinfection. The clinical picture varies from asymptomatic to life-threatening hyperinfection syndrome. There is concern about increasing prevalence in Europe due to the number of cases imported by migrants and travelers.</div></div><div><h3>Methods</h3><div>This is a retrospective chart review of patients evaluated at the Charité Tropical Medicine outpatient clinic in Berlin, Germany. Cases were identified based on either a positive serologic test for <em>Strongyloides</em> (i.e., probable cases) or the detection of <em>Strongyloides</em> larvae in stool samples (i.e., confirmed cases).</div></div><div><h3>Results</h3><div>From April 2018 to November 2023, 162 patients with <em>Strongyloides</em> infection were identified. Diagnosis was confirmed in 49 patients (30.2 %) and probable in 113 patients (69.8 %). About half of the patients (48.8 %) were classified as migrants, who were diagnosed through screening in 48.1 %. Eosinophilia was present in 27.6 % of all patients, with no significant differences between migrants and non-migrants, or between probable or confirmed infections. In patients with a positive stool microscopy, only 8/37 (21.6 %) had a positive serology.</div></div><div><h3>Conclusion</h3><div>Nearly half of the migrant cases were detected through serology as part of screening. Most patients had no eosinophilia, and the positivity of serological tests was very low in patients with positive stool microscopy. These findings highlight the usefulness of targeted screening strategies in risk populations and suggest implementing sensitive stool tests detecting larvae combined with serology, to improve case detection.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"70 ","pages":"Article 102952"},"PeriodicalIF":4.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145985342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Converging influenza threats: Seasonal A(H3N2) (including subclade K) dynamics and the persistent pandemic risk of A(H5N1)","authors":"Jaime David Acosta-España ,&nbsp;Jenny Belén Altamirano-Jara ,&nbsp;D. Katterine Bonilla-Aldana ,&nbsp;Erika Tatiana Chica-Granados ,&nbsp;Alfonso J. Rodriguez-Morales","doi":"10.1016/j.tmaid.2025.102949","DOIUrl":"10.1016/j.tmaid.2025.102949","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"69 ","pages":"Article 102949"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145828586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}