Travel Medicine and Infectious Disease最新文献

{"title":"The first possible case of airport Zika virus infection in the EU/EEA","authors":"Jana Kerlik ,&nbsp;Ján Hockicko ,&nbsp;Mária Avdičová ,&nbsp;Monika Musilová ,&nbsp;Veronika Tarkovská ,&nbsp;Elena Tichá ,&nbsp;Hana Zelená","doi":"10.1016/j.tmaid.2025.102864","DOIUrl":"10.1016/j.tmaid.2025.102864","url":null,"abstract":"<div><div>Since 2019, when the first autochthonous cases of ZIKV disease were observed in EU/EEA countries, no other locally acquired ZIKV disease cases have been reported in EU/EEA.</div><div>Our case of ZIKV disease in 2024 had a history of flying from Slovakia to Italy and back through Hungary. Since other human routes of ZIKV transmission have been ruled out, we describe the first case of possible ZIKV transmission through airport mosquitoes in EU/EEA.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"66 ","pages":"Article 102864"},"PeriodicalIF":6.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143931829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital tuberculosis in a preterm neonate linked to female genital tuberculosis in a migrant mother: A case report","authors":"Ludo Mahieu ,&nbsp;Aikaterini Barka ,&nbsp;Wouter Arrazola de Oñate ,&nbsp;Veerle Matheeussen ,&nbsp;Koen Vanden Driessche","doi":"10.1016/j.tmaid.2025.102859","DOIUrl":"10.1016/j.tmaid.2025.102859","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"66 ","pages":"Article 102859"},"PeriodicalIF":6.3,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitudes, practices and vaccine acceptance towards seasonal influenza vaccination among international travelers: a cross-sectional survey in Thailand","authors":"Pathomthep Leowattana ,&nbsp;Viravarn Luvira ,&nbsp;Noppadon Tangpukdee ,&nbsp;Panita Looareesuwan ,&nbsp;Tanaya Siripoon ,&nbsp;Thundon Ngamprasertchai ,&nbsp;Suparat Phuanukoonnon ,&nbsp;Pornthep Chanthavanich","doi":"10.1016/j.tmaid.2025.102863","DOIUrl":"10.1016/j.tmaid.2025.102863","url":null,"abstract":"<div><h3>Background</h3><div>Influenza is a common but preventable disease. International travelers encounter significant risks in contracting influenza.</div></div><div><h3>Methods</h3><div>The cross-sectional, questionnaire-based study was conducted on international travelers while visiting the Thai Travel Clinic at the Hospital for Tropical Diseases in Bangkok, Thailand.</div></div><div><h3>Results</h3><div>From May to November 2024, 250 Thai and 229 non-Thai international travelers were enrolled. Most participants reported sufficient knowledge about influenza, with 86.4 % achieving a score of ≥60 % while expressing mild concern of infection [mean perceived risk score of 3.1 ± 2.4 (range from 0 to 10)]. When regarding preventive measures, 72.2 % reported regular hand hygiene, while only 19.4 % regularly wore masks in public. Influenza vaccine acceptance was 38.2 %. The most influential reason for vaccination was healthcare personnel's advice. In the multivariable analysis, the independent factors which affected vaccine acceptance were travelers' nationality, age, purpose of travel, destination country, and perceived risk score.</div></div><div><h3>Conclusion</h3><div>International travelers had sufficient influenza knowledge but low awareness relating to influenza prevention methods and influenza vaccinations. Low vaccine acceptance rates were observed among international travelers. Travel consultations should focus on influenza awareness while traveling and associated preventative measures.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"66 ","pages":"Article 102863"},"PeriodicalIF":6.3,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oropouche Fever: An imported case underscoring the importance of clinical and epidemiological vigilance","authors":"M. Migueres ,&nbsp;C. Garnier ,&nbsp;P. Trémeaux ,&nbsp;G. Durand ,&nbsp;G. Martin-Blondel ,&nbsp;L. Pezzi ,&nbsp;J.-M. Mansuy","doi":"10.1016/j.tmaid.2025.102862","DOIUrl":"10.1016/j.tmaid.2025.102862","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"66 ","pages":"Article 102862"},"PeriodicalIF":6.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rabies post-exposure treatment in metropolitan Sydney residents, 2013–2023: A retrospective case-series analysis","authors":"Alice Self ,&nbsp;Troy McNeill ,&nbsp;Andrew Ingleton ,&nbsp;Thomas R. Browne ,&nbsp;Leena Gupta","doi":"10.1016/j.tmaid.2025.102856","DOIUrl":"10.1016/j.tmaid.2025.102856","url":null,"abstract":"<div><h3>Background</h3><div>The nature and frequency of rabies and Australian Bat Lyssavirus (ABLV) exposures requiring post-exposure treatment (PET) in metropolitan Sydney residents has not previously been described. We assessed the trends in PET use in this population, the nature of exposures, geographic distribution, and timeliness and completeness of PET provided, comparing between local and overseas exposures.</div></div><div><h3>Methods</h3><div>A retrospective case series analysis of potential rabies and ABLV exposures in residents of Sydney Local Health District reported to the public health unit between January 1, 2013 and December 31, 2023.</div></div><div><h3>Results</h3><div>Data were available for 595 exposed persons; 477 (80 %) were overseas exposures, and 118 (20 %) were local ABLV exposures. PET was administered in 587 (99 %) exposures. Overseas exposures were mostly due to bites from monkeys, and the majority occurred in Asia (92 %), specifically in Indonesia. Local exposures were mostly due to megabat injuries. Bat testing occurred following 25 % of local exposures, with a 20 % ABLV positivity rate. Inadequate wound management was reported in 45 % of exposures. PET was markedly delayed (commenced greater than 14 days after exposure or a mid-schedule delay) in 26 % of overseas and 7 % of local exposures and incomplete in 15 % of overseas and 4 % of local exposures. Only 8 % of exposed persons received pre-exposure prophylaxis (PrEP).</div></div><div><h3>Conclusion</h3><div>Cost reduction strategies and measures to improve adherence and accessibility to PET, such as prepositioned stock and standing orders, should be explored. Improving public health risk communication about animal avoidance and appropriate treatment if exposed may also reduce delayed and incomplete PEP. Australian travelers to rabies-endemic countries should be routinely counselled on the benefits of PrEP.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102856"},"PeriodicalIF":6.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malaria risk perceptions and barriers for effective prophylaxis among sub-Saharan African 'visiting friends and relatives' travellers in Hamburg, Germany","authors":"Marabelle N. Essandoh ,&nbsp;Maria S. Mackroth ,&nbsp;Thomas Theo Brehm ,&nbsp;Pia Michelitsch ,&nbsp;Franck Ekoka Mbassi ,&nbsp;Maximilian Rakotonirinalalao ,&nbsp;Kayode Ijagbemi ,&nbsp;Michael Ramharter","doi":"10.1016/j.tmaid.2025.102858","DOIUrl":"10.1016/j.tmaid.2025.102858","url":null,"abstract":"<div><h3>Background</h3><div>The African visiting friends and relatives (VFR) community in the Global North is at high risk of contracting preventable travel-associated infections including malaria when travelling to sub-Saharan Africa. This study aimed to assess barriers to effective prevention and to develop tailored travel counselling.</div></div><div><h3>Methods</h3><div>A questionnaire-based survey was conducted from January to August 2023 at the Hamburg Airport among adult sub-Saharan African VFR travellers returning from malaria-endemic destinations in Africa to assess malaria risk perceptions, attitudes towards prophylaxis and counselling and their experiences with travel medicine and malaria prophylaxis.</div></div><div><h3>Results</h3><div>A total of 389 participants completed the survey. Of these, 67 % (n = 261) demonstrated adequate knowledge of malaria transmission. Fifty-one percent (n = 198) perceived minimal risk of contracting malaria in the malaria-endemic country leading to lower uptake of prophylaxis. Ten percent (n = 37) mistakenly believed they were vaccinated against malaria. Approximately half of the respondents did not seek medical travel advice prior to departure or take antimalarial prophylaxis due to perceived minimal risk of disease. Of those who took antimalarial drugs, 77 % (n = 149) completed the full course. On return, 5 % (n = 20) of the respondents had malaria-like symptoms and of these, 55 % (n = 11) either self-medicated or did not seek medical treatment.</div></div><div><h3>Conclusions</h3><div>VFR travellers mistakenly perceive a low risk of malaria, resulting in low uptake of travel medical advice and chemoprophylaxis. Mistrust of advice from healthcare providers was found. Insights from this survey are valuable for practitioners and travel medicine clinics to provide more tailored and culturally sensitive travel advice to VFR travellers.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102858"},"PeriodicalIF":6.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Olinda María Delgado Silva, PhD: A trailblazer in Venezuelan parasitology and a beloved mentor to generations","authors":"Alfonso J. Rodriguez-Morales ,&nbsp;Vanessa Aguilera-Volkman","doi":"10.1016/j.tmaid.2025.102844","DOIUrl":"10.1016/j.tmaid.2025.102844","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102844"},"PeriodicalIF":6.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe mpox clade II infection in an immunocompromised HIV patient: Case report and therapeutic approach","authors":"Serena Vita ,&nbsp;Dimitra Kontogiannis ,&nbsp;Francesca Faraglia ,&nbsp;Alessandra D'Abramo ,&nbsp;Valentina Mazzotta ,&nbsp;Alessandra Scarabello ,&nbsp;Claudia Palazzolo ,&nbsp;Angela Corpolongo ,&nbsp;Andrea Antinori ,&nbsp;Emanuele Nicastri","doi":"10.1016/j.tmaid.2025.102860","DOIUrl":"10.1016/j.tmaid.2025.102860","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102860"},"PeriodicalIF":6.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143918498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fever in travelers returning from tropical and subtropical areas: a hospital-based study of factors affecting investigations and diagnoses in children and adults","authors":"Klara Sondén ,&nbsp;Donya Satarvandi ,&nbsp;Helena Hildenwall ,&nbsp;Sara Falck-Jones ,&nbsp;Victor Yman ,&nbsp;Niclas Johansson ,&nbsp;Katja Wyss ,&nbsp;Elin Folkesson ,&nbsp;Hilmir Asgeirsson ,&nbsp;Irene Nordling ,&nbsp;Anna Löwhagen Welander ,&nbsp;Anna Färnert","doi":"10.1016/j.tmaid.2025.102861","DOIUrl":"10.1016/j.tmaid.2025.102861","url":null,"abstract":"<div><h3>Background</h3><div>As global travel surges in the post-pandemic era, healthcare systems must prepare for proper management of diseases encountered by returning travelers.</div></div><div><h3>Method</h3><div>A retrospective study of the management of returning travelers from tropical or subtropical regions, with fever at the adult and paediatric emergency departments of Karolinska University Hospital, Stockholm Sweden. Demographics, travel history, clinical and microbiology data were extracted from health records. Multivariate regression analyses identified factors affecting investigations and diagnoses.</div></div><div><h3>Results</h3><div>A total of 2441 patients (2197 adults, 244 children) were included. An etiological diagnosis was confirmed in 63.3 % (n = 1546) of patients; with malaria (5.6 %, n = 138), dengue (4.0 %, n = 98) and typhoid fever (0.9 %, n = 22) being the most common tropical infections. Patients with fever &gt;38 °C (aOR 1.48, 95 % CI 1.20–1.84) or hospitalization (aOR 4.68, 95 % CI 3.23–6.80) had higher odds of etiological diagnosis. Children were less likely than adults to have a cause of fever diagnosed (OR 0.64, 95 % CI 0.49–0.84). Malaria testing was lower in children than adults who had visited Sub-Sahara Africa (80.6 % vs 90.4 %). Overall, a lower proportion of children underwent blood cultures, compared to adults (29.5 % vs 68.7 %). VFR travelers and migrants had lower probability of other microbiological investigations when malaria testing was negative (aOR 0.69, 95 % CI 0.54–0.90; aOR 0.67, 95 % CI 0.50–0.90).</div></div><div><h3>Conclusion</h3><div>The management of febrile patients following tropical travel varied significantly across different patient groups. Children, migrants and VFR travelers often receive less thoroughly investigations. This highlights the need for equitable management and investigation, especially for these vulnerable populations.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102861"},"PeriodicalIF":6.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Operational challenges and lessons learned from conducting febrile surveillance in a long-term randomized dengue vaccine trial in Latin America and Asia-Pacific","authors":"Harald Pfaar ,&nbsp;Eduardo López-Medina ,&nbsp;Ian Escudero ,&nbsp;Yanee Hutagalung ,&nbsp;Nicholas Roubinis ,&nbsp;Seloni Thakrar ,&nbsp;Charissa Fay Corazon Borja-Tabora ,&nbsp;Vianney Tricou ,&nbsp;Suely Tuboi","doi":"10.1016/j.tmaid.2025.102840","DOIUrl":"10.1016/j.tmaid.2025.102840","url":null,"abstract":"<div><h3>Background</h3><div>In trials, dengue vaccine efficacy evaluation relies on participants presenting with febrile illness/clinically suspected dengue contacting the study site for sample collection and clinical assessment within a short timeframe. Here, we present key considerations to maintain high compliance with the febrile surveillance procedures in a trial that assessed TAK-003 efficacy.</div></div><div><h3>Methods</h3><div>DEN-301 (NCT02747927) is a randomized phase 3 trial in children/adolescents from eight dengue-endemic countries in Latin America (LATAM) and Asia-Pacific (APAC). Febrile surveillance consisted of weekly contact with the participant to identify cases of fever (≥38 °C; two of three consecutive days). Blood samples were collected for molecular testing, preferably ≤5 days of fever onset, together with thorough clinical assessment by the investigators. The data are presented descriptively.</div></div><div><h3>Results</h3><div>Of the 20,071 (LATAM, 11,080; APAC, 8991) participants who received TAK-003/placebo, 18,260 (91.0 %) completed 4.5 years of follow-up. The overall incidence of febrile illness was 30 (LATAM, 26.0; APAC, 35.1) cases per 100 person-years. The rate samples collected during the acute phase was 98.1 %. The overall rate of samples collected after 5 days of fever onset (missed/out-of-window) was 6 % (LATAM, 10 %; APAC, 2 %). A trend toward reduced missed/out-of-window samples was observed after implementing measures, such as transportation, engagement, and healthcare aid tailored per study site in 2017, which appeared to increase during the COVID-19 pandemic.</div></div><div><h3>Conclusion</h3><div>The design of the febrile surveillance protocol ensured high compliance in the trial. Maintaining engagement and access to healthcare beyond the protocol was important in improving febrile case evaluation ≤5 days of fever onset.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102840"},"PeriodicalIF":6.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}