Travel Medicine and Infectious Disease最新文献_第2页

Intermittent preventive treatment regimens for malaria in HIV-positive pregnant women: Systematic review and meta-analysis of clinical trials hiv阳性孕妇疟疾间歇预防治疗方案：临床试验的系统回顾和荟萃分析。

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-17 DOI: 10.1016/j.tmaid.2025.102908

Ammar Elgadi , Tibyan Noorallah , Egbal Abdelazim , Sara Altraifi , Hajir Altraifi , Ammar Elhaj , Walaa Elnaiem , Lina Hemmeda

{"title":"Intermittent preventive treatment regimens for malaria in HIV-positive pregnant women: Systematic review and meta-analysis of clinical trials","authors":"Ammar Elgadi , Tibyan Noorallah , Egbal Abdelazim , Sara Altraifi , Hajir Altraifi , Ammar Elhaj , Walaa Elnaiem , Lina Hemmeda","doi":"10.1016/j.tmaid.2025.102908","DOIUrl":"10.1016/j.tmaid.2025.102908","url":null,"abstract":"<div><h3>Background</h3><div>The WHO recommended the use of intermittent preventive treatment (IPT) regimens for malaria in HIV-positive pregnant women living in endemic areas to prevent malaria-related perinatal complications. However, the high drug resistance rates make the effectiveness of the various available options questionable.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis was conducted according to the PRISMA guidelines and registered in Prospero (ID: CRD42024579942). PubMed, Scopus, and Cochrane libraries were searched in June 2024 for relevant studies. Randomized clinical trials reporting the use of ITP for malaria in HIV-infected pregnant women were included. The incidence of peripheral malaria diagnosis was our primary extracted outcome. RevMan 5.3 was used for meta-analysis.</div></div><div><h3>Results</h3><div>Thirteen clinical trials with 5226 HIV-positive pregnant patients were included. ITP showed 55 % lower odds of malaria during pregnancy or at delivery (OR = 0.45, 95 % CI: 0.36, 0.56, P ≤ 0.001), with IPTp-DP (Dihydroartemisinin-Piperaquine) being the most effective regimen. However, despite reducing the odds of placental malaria by 48 % (OR = 0.52, 95 % CI: 0.39, 0.70, P ≤ 0.001), ITP showed no significant effect on low birth weight, fetal loss, stillbirth, or preterm labor. Furthermore, IPT reduces the odds of maternal anemia by 18 % (OR = 0.82, 95 % CI: 0.69, 0.97, P = 0.03).</div></div><div><h3>Conclusion</h3><div>IPT was shown to be effective in reducing malaria-related maternal complications, including malaria during pregnancy, at delivery, or placental and maternal anemia. However, it showed no effective impact on adverse birth outcomes. Further research may be necessary to explore birth-related outcomes.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"68 ","pages":"Article 102908"},"PeriodicalIF":4.7,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renaming the tropical febrile syndrome: A clinical and semantic imperative in global health. 重命名热热综合征：全球健康的临床和语义必要性。

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-15 DOI: 10.1016/j.tmaid.2025.102905

Carlos Arturo Alvarez-Moreno, Jorge Alberto Cortes, Carlos Humberto Saavedra, Álvaro A Faccini-Martínez, Sonia Isabel Cuervo-Maldonado, Alfonso J Rodriguez-Morales

引用次数: 0

Genetic characterization of enteric protozoan microorganisms in newly arrived migrants in Italy and correlation with the gut microbiome layout 意大利新移民肠道原生动物微生物的遗传特征及其与肠道微生物群布局的相关性

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-01 DOI: 10.1016/j.tmaid.2025.102901

Marianna Marangi , Giorgia Palladino , Felice Valzano , Daniel Scicchitano , Silvia Turroni , Simone Rampelli , Marco Candela , Fabio Arena

{"title":"Genetic characterization of enteric protozoan microorganisms in newly arrived migrants in Italy and correlation with the gut microbiome layout","authors":"Marianna Marangi , Giorgia Palladino , Felice Valzano , Daniel Scicchitano , Silvia Turroni , Simone Rampelli , Marco Candela , Fabio Arena","doi":"10.1016/j.tmaid.2025.102901","DOIUrl":"10.1016/j.tmaid.2025.102901","url":null,"abstract":"<div><div>The prevalence of the enteric protozoan microorganisms, its genetic characterization as well as its associated gut microbiome has been molecularly and 16S metagenomic characterized in a cohort of newly arrived migrants in Italy from African countries over the period 2022–2024. Out of 199 individuals, 92 (46.2%) were found to be carrier of protozoan microorganisms with a higher prevalence of <em>Blastocystis</em> sp. (15.5%), followed by <em>Giardia duodenalis</em> (12.6%), <em>Dientamoeba fragilis</em> (7.5%), <em>Cryptosporidium parvum</em> (6.5%), and <em>Entamoeba histolytica</em> (4%). Subtypes ST1, ST2 and ST3 were genetically characterized for <em>Blastocystis</em> sp., assemblages A and B for <em>G. duodenalis</em>, subtypes families IIa and IIc for <em>C. parvum</em> and genotype 1 for <em>D. fragilis</em>. High prevalence of <em>Butyrivibrio</em>, <em>Lachnospiraceae UGC 10</em> and <em>Paraprevotella</em>, were identified in the protozoan non-carrier individual group. This work shed lights on the circulation of enteric protozoan microorganisms in apparently healthy migrants from African countries and the potential relationship with the host-microbiome composition. Moreover, these results give an overview of the importance of microbiological surveys among migrants and asylum seekers arriving to hosting countries in order to evaluate the reliable risk of several microorganisms introduction though migration. Ultimately, further investigation of interplays between the intestinal microbiota and protozoan microorganisms will provide new approaches in the diagnosis and treatment of intestinal infections.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102901"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of health problems related to marine tourism among travelers in the Andaman Coast provinces of Southern Thailand 泰国南部安达曼海岸各省游客中与海洋旅游有关的健康问题的流行情况。

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-01 DOI: 10.1016/j.tmaid.2025.102913

Vitat Tipphayawong , Pat Chantapinya , Ranida Techasuwanna , Amornphat Kitro

{"title":"Prevalence of health problems related to marine tourism among travelers in the Andaman Coast provinces of Southern Thailand","authors":"Vitat Tipphayawong , Pat Chantapinya , Ranida Techasuwanna , Amornphat Kitro","doi":"10.1016/j.tmaid.2025.102913","DOIUrl":"10.1016/j.tmaid.2025.102913","url":null,"abstract":"<div><h3>Background</h3><div>Marine tourism is increasing in popularity in Thailand, contributing to a rise in associated medical issues. The aim of this report was to assess the prevalence and severity of marine-related health problems and associated risk factors.</div></div><div><h3>Methods</h3><div>A retrospective study was conducted from October 2021 to September 2024 across three healthcare centers in southern Thailand.</div></div><div><h3>Results</h3><div>520 cases were analyzed, 57 % (n = 295) were male and 93.7 % (n = 487) were international travelers, 62.7 % (n = 326) from Europe. Common diagnoses included marine envenomation (24.0 %, n = 125), ear infection (21.7 %, n = 113), and trauma (18.7 %, n = 97). Most health incidents occurred coastal areas (46.7 %, n = 243). 29.0 % (n = 151) visited emergency department and 6.0 % (n = 31) resulted in death. Severe outcomes were associated with male gender, age over 40 years, and sea-based activities.</div></div><div><h3>Conclusion</h3><div>Most marine-related health issues were non-severe, specific risks varied by location, highlighting the need for location-specific preventive measures.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102913"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous myiasis in a Serbian traveller returning from Kenya 从肯尼亚返回的塞尔维亚旅行者皮肤蝇蛆病。

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-01 DOI: 10.1016/j.tmaid.2025.102904

Stefan Momčilović , Anson V. Koehler , Robin B. Gasser

{"title":"Cutaneous myiasis in a Serbian traveller returning from Kenya","authors":"Stefan Momčilović , Anson V. Koehler , Robin B. Gasser","doi":"10.1016/j.tmaid.2025.102904","DOIUrl":"10.1016/j.tmaid.2025.102904","url":null,"abstract":"<div><h3>Background</h3><div>Cutaneous myiasis is an ectoparasitic disease caused by fly larvae. In non-endemic regions it is rare, often unfamiliar to clinicians and readily misdiagnosed.</div></div><div><h3>Case presentation</h3><div>A 24-year-old Serbian traveller developed painful furuncular lesions on the thigh after returning from Kenya. The lesions were initially treated as insect bites with intramuscular corticosteroid, antihistamines and topical betamethasone–gentamicin. Spontaneous expulsion of a larva led to the recognition of myiasis.</div></div><div><h3>Methods and results</h3><div>Three third-instar (L3) larvae were surgically removed. Morphological features and mitochondrial <em>cox</em>1 sequencing identified <em>Cordylobia anthropophaga</em>. Genetic analysis confirmed 99 % identity with reference sequences.</div></div><div><h3>Conclusion</h3><div>This case highlights the challenges associated with diagnosis of furuncular myiasis in travellers. Awareness of travel history, maintenance of clinical suspicion and molecular analysis are essential for accurate diagnosis. Timely larval removal and prophylactic antibiotics minimise complications and improve outcomes.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102904"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An imported case of Haplorchis taichui infection diagnosed with molecular genomics in France. 法国输入性太水单螺旋体感染1例分子基因组学诊断。

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-01 Epub Date: 2025-08-06 DOI: 10.1016/j.tmaid.2025.102888

Victor Luzarraga, Maxime Moniot, Patricia Combes, Mathilde Legay, Philippe Poirier, Céline Nourrisson

{"title":"An imported case of Haplorchis taichui infection diagnosed with molecular genomics in France.","authors":"Victor Luzarraga, Maxime Moniot, Patricia Combes, Mathilde Legay, Philippe Poirier, Céline Nourrisson","doi":"10.1016/j.tmaid.2025.102888","DOIUrl":"10.1016/j.tmaid.2025.102888","url":null,"abstract":"<p><strong>Purpose: </strong>We report here on an imported case of Haplorchis taichui infection in a Western country. Given their rarity in these countries, such diagnoses of heterophyid flukes can be particularly difficult.</p><p><strong>Methods: </strong>The stool of a 70-year-old Laotian woman with eosinophilia was sent to the laboratory for examination. Microscopic observations based on direct examination and two concentration methods were performed on the fecal sample. After extraction of DNA from the sample, Sanger sequencing of the internal transcribed spacer 2 (ITS2) region and the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene was carried out.</p><p><strong>Results: </strong>Ellipsoid eggs with a convex operculum and abopercular knob were observed on microscopic examination, suggestive of fluke eggs, but there was no morphological criterion to distinguish between opisthorchiid and heterophyid eggs. Results of ITS2 and cox1 sequencing matched the intestinal fluke Haplorchis taichui.</p><p><strong>Conclusion: </strong>This case report points out that small trematode eggs can hardly be used to distinguish between opisthorchiid and heterophyid flukes in fecal examinations, and underlines the need for molecular genomic studies to establish an accurate species diagnosis.</p>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":" ","pages":"102888"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunisation in pregnancy – Weighing the unknown to balance benefits and risks impacting women, offspring, and development 妊娠期免疫——权衡未知因素，平衡影响妇女、后代和发育的益处和风险。

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-01 DOI: 10.1016/j.tmaid.2025.102889

Stephen Toovey MBBCh PhD , Jessica A. Hellings MBBCh, M.Med

引用次数: 0

Extended Lake Louise Score: a novel standard evaluation of cognitive impairment for immigrants' rapid ascent to high altitude 扩展路易斯湖得分：移民快速上升到高海拔认知障碍的新标准评估。

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-01 DOI: 10.1016/j.tmaid.2025.102907

Tao Xu , Wen Li , Chun-Yan Zhang , Bo Dong , Tao Luo , Jian-Guo Huang , Jin-Long Shi , Jun Tang , Shi-Jun Li

{"title":"Extended Lake Louise Score: a novel standard evaluation of cognitive impairment for immigrants' rapid ascent to high altitude","authors":"Tao Xu , Wen Li , Chun-Yan Zhang , Bo Dong , Tao Luo , Jian-Guo Huang , Jin-Long Shi , Jun Tang , Shi-Jun Li","doi":"10.1016/j.tmaid.2025.102907","DOIUrl":"10.1016/j.tmaid.2025.102907","url":null,"abstract":"<div><h3>Objective</h3><div>To extend the Lake Louise Scoring (LLS) system to better assess cognitive impairment, and investigate the early changes of hematological indicators for subjects of rapid ascent to high altitude.</div></div><div><h3>Methods</h3><div>One hundred and eighty-nine subjects underwent routine hematology, urine and psychological examination at the altitude of 1500 m in February, and did that again after they had ascended to 3860 m in 2 days. Subjects were evaluated with eLLS using a combination of self-reported cognitive assessment and a diagnosis of AMS based on 4-item Lake Louise Score (LLS) of Acute Mountain Sickness (AMS). Next year, a follow-up validation was conducted in the same area.</div></div><div><h3>Results</h3><div>Sixty-eight subjects were diagnosed AMS with LLS and 92 subjects met the diagnostic criteria of eLLS among 189 subjects. The difference in hematological indicators calculated by the eLLS criteria was more significant than that calculated by the LLS criteria, which including red blood cells (P < 0.01), white blood cells (P < 0.05), hemoglobin (P < 0.01), platelets (P < 0.01) and neutrophils (P < 0.01). The eLLS identified additional risk factors comparing with LLS, which included higher white blood cells (OR 1.660, 95 % CI 1.032–2.670, P < 0.05), neutrophils (OR 1.312, 95 % CI 1.002–1.718, P < 0.05). Follow-up results showed that there were more significant differences in psychological scale scores between the groups identified using the eLLS criteria. (P < 0.05).</div></div><div><h3>Conclusion</h3><div>We proposed eLLS standard for individuals rapidly ascending to high altitude, which is more sensitive to hematological changes and can better reflect the cognitive mental state than the LLS.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102907"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reemergence of Oropouche in the Brazilian Amazon: A phylodynamic and phylogenetic analysis. 巴西亚马逊河流域大鼠的重新出现：系统动力学和系统发育分析。

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-01 Epub Date: 2025-07-25 DOI: 10.1016/j.tmaid.2025.102877

Karolaine Santos Teixeira, Hillquias Monteiro Moreira, Tárcio Peixoto Roca, Edilene Pereira Pimentel, Jackson Alves da Silva Queiroz, Jessiane Rodrigues Ribeiro, Ana Maisa Passos-Silva, Adrhyan Araújo, Kátia Ingred da Silva Maia, Felipe Gomes Naveca, Ighor Arantes, Gonzalo Bello, Jansen Fernandes de Medeiros, Marco Aurelio Krieger, Juan Miguel Villalobos Salcedo, Rita de Cássia Pontello Rampazzo, Deusilene Vieira

{"title":"Reemergence of Oropouche in the Brazilian Amazon: A phylodynamic and phylogenetic analysis.","authors":"Karolaine Santos Teixeira, Hillquias Monteiro Moreira, Tárcio Peixoto Roca, Edilene Pereira Pimentel, Jackson Alves da Silva Queiroz, Jessiane Rodrigues Ribeiro, Ana Maisa Passos-Silva, Adrhyan Araújo, Kátia Ingred da Silva Maia, Felipe Gomes Naveca, Ighor Arantes, Gonzalo Bello, Jansen Fernandes de Medeiros, Marco Aurelio Krieger, Juan Miguel Villalobos Salcedo, Rita de Cássia Pontello Rampazzo, Deusilene Vieira","doi":"10.1016/j.tmaid.2025.102877","DOIUrl":"10.1016/j.tmaid.2025.102877","url":null,"abstract":"<p><strong>Background: </strong>The distribution of arboviruses in endemic regions is experiencing a significant shift, along with the re-emergence of Oropouche virus (OROV) as a significant pathogen, characterized by dynamic vector-borne transmission. Despite growing public health relevance, OROV remains insufficiently characterized, with limited comprehensive genomic and epidemiological data. This knowledge gap affects the accuracy of diagnostic approaches and limits the effectiveness of surveillance and control strategies. This study aimed to characterize the re-emergence of OROV in endemic regions, elucidate its epidemiological distribution, and clarify the epidemiological distribution of OROV and assess its impact on diagnostic strategies and surveillance for acute febrile illness.</p><p><strong>Methods: </strong>Between January and July 2024, a total of 869 individuals with malaria-negative acute febrile illness were screened for dengue, Zika, and chikungunya viruses. Duplex RT-qPCR assays were subsequently employed to detect Mayaro and Oropouche viruses. Spatiotemporal and geospatial analyses were conducted to assess the distribution of OROV in relation to environmental factors.</p><p><strong>Findings: </strong>Among the participants, 35 % tested positive for OROV, with cases predominantly concentrated in forest and riverine areas. Considering that the significant increase in the number of cases occurred in a short space of time, the results highlight the urgent need to strengthen genomic and epidemiological surveillance to tackle emerging arboviral threats.</p>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":" ","pages":"102877"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological characteristics and environmental contamination of monkeypox in Beijing's Chaoyang district: Field evidence from 2023 to 2024 北京市朝阳区猴痘流行病学特征及环境污染：2023 - 2024年现场证据

IF 4.7 3区医学

Travel Medicine and Infectious Disease Pub Date : 2025-09-01 DOI: 10.1016/j.tmaid.2025.102896

Chenming Huang , Yunkang Zhao , Baihui Han , Ye Zhang , Huan Zhang , Xin Zhao , Zeyu Zhao , Ke Wu , Yang Lin , Dingyan Zhang , Fanglei Zhang , Han Meng , Jiaqi Wang , Tianmu Chen , Xiao Qi

{"title":"Epidemiological characteristics and environmental contamination of monkeypox in Beijing's Chaoyang district: Field evidence from 2023 to 2024","authors":"Chenming Huang , Yunkang Zhao , Baihui Han , Ye Zhang , Huan Zhang , Xin Zhao , Zeyu Zhao , Ke Wu , Yang Lin , Dingyan Zhang , Fanglei Zhang , Han Meng , Jiaqi Wang , Tianmu Chen , Xiao Qi","doi":"10.1016/j.tmaid.2025.102896","DOIUrl":"10.1016/j.tmaid.2025.102896","url":null,"abstract":"<div><h3>Objectives</h3><div>The mpox outbreak in Beijing's Chaoyang District after late May 2023, this study aims to evaluate the epidemiological characteristics and environmental contamination of this outbreak.</div></div><div><h3>Methods</h3><div>A field investigation was conducted to evaluate the epidemiological characteristics of mpox cases and their living environments in Chaoyang District, Beijing, between May 2023 and May 2024. Laboratory testing, epidemiological description, and statistical analysis were conducted subsequently.</div></div><div><h3>Results</h3><div>The outbreak resulted in 43 non-fatal cases, 97.67 % were Men who have Sex with Men (MSM) and symptomatic, tracking a peak in August 2023 and declining thereafter. Travel history was reported in 27.91 % (12 of 43), and coinfections with both HIV and syphilis were among 16.28 % of mpox cases. MPXV-positive rates were 97.67 % for rash swabs, 55.81 % for throat swabs, and 59.38 % for environmental samples. Median cycle threshold (Ct) values were 20.45 (IQR: 4.57) for rash swabs, 31.59 (IQR: 5.64) for throat swabs, and 33.33 (IQR: 4.37) for environmental samples. Contact tracing revealed a 9.09 % prevalence among close contacts and a secondary attack rate of 10.26 %. High environmental contamination was found in bedrooms and items such as electronics and cups.</div></div><div><h3>Conclusions</h3><div>The mpox outbreak in Beijing's Chaoyang District predominantly affected MSM, that transmitted through diverse transmission routes. Environmental contamination in long-lived rooms or used items highlights the importance of targeted hygiene measures.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"67 ","pages":"Article 102896"},"PeriodicalIF":4.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144921656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0