Travel Medicine and Infectious Disease最新文献

{"title":"Metagenomic next-generation sequencing enhances the diagnosis of Q fever: A retrospective observational study","authors":"Lingxiao Sun ,&nbsp;Yuyao Yin ,&nbsp;Yifan Guo,&nbsp;Hongbin Chen,&nbsp;Hui Wang","doi":"10.1016/j.tmaid.2025.102845","DOIUrl":"10.1016/j.tmaid.2025.102845","url":null,"abstract":"<div><h3>Background</h3><div>Q fever, a global zoonosis, poses a significant challenge for public health due to its varied and nonspecific clinical presentations, making diagnosis difficult. Metagenomic next-generation sequencing (mNGS) is a potential tool for diagnosing Q fever.</div></div><div><h3>Methods</h3><div>This retrospective observational study was conducted on patients with Q fever admitted to Peking University People's Hospital, from May 2023 to November 2024. mNGS was performed using the patient's peripheral blood, and the qPCR of <em>Coxiella burnetii</em> was also adopted. Subsequently, the clinical data of patients diagnosed with Q fever were systematically evaluated.</div></div><div><h3>Results</h3><div>Twelve peripheral blood samples of 12 patients were detected <em>Coxiella burnetii</em> positive by mNGS. Most patients were male (10, 83.33 %). Fever (12, 100 %), muscle soreness (8, 66.7 %), and headache (4, 33.3 %) were the most common clinical manifestations. Specific qPCR of <em>Coxiella burnetii</em> was detected positive in 8 patients. Chronic Q fever was diagnosed in two patients, who had aortic valve replacement, and their immunological markers, like anti-nuclear were elevated. Once the diagnosis was clear, proper antibiotics were used, and all patients were discharged in better health.</div></div><div><h3>Conclusion</h3><div>Metagenomic next-generation sequencing enhances the diagnosis of Q fever, especially for patients displaying atypical and various clinical symptoms and having unclear epidemiological data or histories of antibiotic use.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102845"},"PeriodicalIF":6.3,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mpox knowledge, risk perception, attitudes and willingness to vaccinate in Colombia's LGBTIQ+ communities: Online survey (CoSex)","authors":"Cándida Diaz-Brochero ,&nbsp;Miguel Barriga ,&nbsp;John Fredy Ramirez ,&nbsp;David Santiago Quevedo ,&nbsp;Geraldine Gomez ,&nbsp;Juliana Mateus ,&nbsp;Natalia Nino-Machado ,&nbsp;Juliana Cuervo-Rojas ,&nbsp;Zulma M. Cucunubá","doi":"10.1016/j.tmaid.2025.102848","DOIUrl":"10.1016/j.tmaid.2025.102848","url":null,"abstract":"<div><h3>Background</h3><div>In the 2022-23 global clade IIb mpox outbreak, Colombia was the sixth country with the most reported cases globally and the second in Latin America after Brazil. LGTBIQ + communities, especially those with extensive sexual networks, were particularly affected.</div></div><div><h3>Objective</h3><div>We aim to characterize the knowledge, risk perceptions, attitudes, and willingness to implement preventive measures against mpox among LGBTIQ + communities in Colombia.</div></div><div><h3>Methods</h3><div>This was an anonymized, cross-sectional, observational study based on a population-based online questionnaire using a participatory approach.</div></div><div><h3>Results</h3><div>Among the 784 participants from 66 municipalities, 49.1 % were aged 18–29 years, and 89.3 % were male and assigned at birth. A total of 73.9 % identified as homosexual, whereas 14.9 % reported never using condoms. Casual sexual partners were reported by 45.4 % of the participants in the past year (median: 3; range: 1–100), and 29.3 % engaged in group sex during the same period (median: 4; range: 2–100). Temporary behavioral changes to reduce mpox risk, such as limiting sexual partners and increasing condom use, were reported by 24.1 % of the participants. Suspected or confirmed mpox infection was reported by 4 % of the participants, with 77.4 % attributing potential exposure to sexual contact. Notably, 89.5 % expressed a willingness to receive mpox vaccination if it was offered.</div></div><div><h3>Conclusions</h3><div>Our findings demonstrate the importance of academic and social communities' cross-collaboration to understand the impact of mpox infection in this population and as a basis for planning epidemic responses to future mpox outbreaks in Colombia and Latin America.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102848"},"PeriodicalIF":6.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for Chagas disease in Latin-American pregnant women and their newborns: A prospective observational, multicenter study in Milan, Italy","authors":"Federico Sabaini ,&nbsp;Andrea Giacomelli ,&nbsp;Beatrice Tassis ,&nbsp;Mariagrazia Ierardi ,&nbsp;Anna Maria Marconi ,&nbsp;Andrea Ronchi ,&nbsp;Irene Cetin ,&nbsp;Lea Testa ,&nbsp;Valeria Savasi ,&nbsp;Elisa Fabbri ,&nbsp;Giulia Alabiso ,&nbsp;Greta Nova ,&nbsp;Michele Vignali ,&nbsp;Nikita Alfieri ,&nbsp;Vania Giacomet ,&nbsp;Martina Beltrami ,&nbsp;Giacomo Casalini ,&nbsp;Margherita Longo ,&nbsp;Silvia Grosso ,&nbsp;Romualdo Grande ,&nbsp;Spinello Antinori","doi":"10.1016/j.tmaid.2025.102846","DOIUrl":"10.1016/j.tmaid.2025.102846","url":null,"abstract":"<div><h3>Objectives</h3><div>Chagas Disease (CD), caused by <em>Trypanosoma cruzi</em>, is endemic in Latin America (LA). However, due to migration, it is now present globally. We aimed to evaluate the prevalence of CD among LA pregnant women in Milan, Italy, and the incidence of <em>T. cruzi</em> transmission to their newborns.</div></div><div><h3>Methods</h3><div>A prospective multicenter observational study was conducted in five different Obstetrics and Gynecology outpatient clinics in Milan, Italy between September 2019 and October 2024. Pregnant women from endemic areas for CD were tested by means of two serological tests directed against <em>T. cruzi</em> antigens. Newborns from positive <em>T. cruzi</em> mothers were screened for <em>T. cruzi</em> infection at birth and at 1, 3 and 9 months.</div></div><div><h3>Results</h3><div>339 women underwent screening for <em>T. cruzi</em> infection with a median age of 33 years [IQR 28–37 years]. Most of them came from Peru (38.3 %), followed by El Salvador (20.6 %) and Ecuador (19.5 %). Six of them tested positive for <em>T. cruzi</em>, accounting for an estimated prevalence of 1.77 % (95 % CI 0.37 %–3.17 %). Two of the affected women were from Bolivia, and the remaining from El Salvador, Brazil, Ecuador and Peru. All 6 children had a negative PCR for <em>T. cruzi</em> infection, and their serology turned negative within the first year of life.</div></div><div><h3>Conclusions</h3><div>The seroprevalence of <em>T. cruzi</em> infection among LA pregnant women in Milan is significant, underscoring the potential occurrence of congenital CD in a non-endemic area like Italy. Raising awareness of this neglected tropical disease among LA women, midwives and gynecologists is crucial.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102846"},"PeriodicalIF":6.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143726082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New World screwworm (Cochliomyia hominivorax) infestation in a returned traveller from Costa Rica","authors":"Amna Majeed ,&nbsp;George Ho ,&nbsp;Antoine Corbeil ,&nbsp;Isaac I. Bogoch","doi":"10.1016/j.tmaid.2025.102843","DOIUrl":"10.1016/j.tmaid.2025.102843","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102843"},"PeriodicalIF":6.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polish travellers on the move: A study of knowledge of travel health and associated practices among polish travellers abroad","authors":"Anna Bogacka ,&nbsp;Agnieszka Wroczyńska ,&nbsp;Maciej Grzybek","doi":"10.1016/j.tmaid.2025.102842","DOIUrl":"10.1016/j.tmaid.2025.102842","url":null,"abstract":"<div><h3>Background</h3><div>Post-pandemic travel has surged, with 1.3 billion journeys recorded worldwide in 2023, reflecting a growing interest in tropical destinations despite the associated health risks. Access to travel health information has improved, yet adherence to preventive measures remains limited due to misinformation, insufficient pre-travel consultations, and concerns about malaria prophylaxis. Based on data from a three-year survey, this study examines the attitudes of Polish travellers to vaccinations, malaria prophylaxis, and COVID-19-related measures.</div></div><div><h3>Methods</h3><div>Surveys conducted during travel festivals from 2021 to 2023 targeted adult participants. A questionnaire designed by experts in travel medicine addressed the demographics, travel behaviours, and health-related practices. Statistical analyses, including chi-squared tests and logistic regression, explored the impact of demographic factors on behaviours, using Python for data analysis.</div></div><div><h3>Results</h3><div>Among 644 participants (mean age 32; 48 % male), 49.5 % reported pre-travel vaccination and 281 intended to use malaria chemoprophylaxis. Gender significantly influenced vaccination status and travel to Africa. The most cited malaria prevention methods were repellents and mosquito nets. Illnesses were reported by 317 participants, with travellers' diarrhoea (185 cases) most common, particularly in Turkey, Egypt, and India. Forty-eight individuals required medical consultations.</div></div><div><h3>Conclusions</h3><div>Education and pre-travel counseling enhance adherence to preventive measures, yet many travellers fail to follow recommendations. Malaria remains the most common travel-imported disease in the EU/EEA, with 4856 cases in 2021. The Capability, Opportunity, and Motivation Behavior (COM-B) model highlights the importance of addressing these factors to improve compliance with preventive behaviours.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102842"},"PeriodicalIF":6.3,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Operational challenges and lessons learned from conducting febrile surveillance in a long-term randomized dengue vaccine trial in Latin America and Asia-Pacific.","authors":"Harald Pfaar, Eduardo López-Medina, Ian Escudero, Yanee Hutagalung, Nicholas Roubinis, Seloni Thakrar, Charissa Fay Corazon Borja-Tabora, Vianney Tricou, Suely Tuboi","doi":"10.1016/j.tmaid.2025.102840","DOIUrl":"https://doi.org/10.1016/j.tmaid.2025.102840","url":null,"abstract":"<p><strong>Background: </strong>In trials, dengue vaccine efficacy evaluation relies on participants presenting with febrile illness/clinically suspected dengue contacting the study site for sample collection and clinical assessment within a short timeframe. Here, we present key considerations to maintain high compliance with the febrile surveillance procedures in a trial that assessed TAK-003 efficacy.</p><p><strong>Methods: </strong>DEN-301 (NCT02747927) is a randomized phase 3 trial in children/adolescents from eight dengue-endemic countries in Latin America (LATAM) and Asia-Pacific (APAC). Febrile surveillance consisted of weekly contact with the participant to identify cases of fever (≥38°C; two of three consecutive days). Blood samples were collected for molecular testing, preferably ≤5 days of fever onset, together with thorough clinical assessment by the investigators. The data are presented descriptively.</p><p><strong>Results: </strong>Of the 20,071 (LATAM, 11,080; APAC, 8991) participants who received TAK-003/placebo, 18,260 (91.0%) completed 4.5 years of follow-up. The overall incidence of febrile illness was 30 (LATAM, 26.0; APAC, 35.1) cases per 100 person-years. The rate samples collected during the acute phase was 98.1%. The overall rate of samples collected after 5 days of fever onset (missed/out-of-window) was 6% (LATAM, 10%; APAC, 2%). A trend toward reduced missed/out-of-window samples was observed after implementing measures, such as transportation, engagement, and healthcare aid tailored per study site in 2017, which appeared to increase during the COVID-19 pandemic.</p><p><strong>Conclusion: </strong>The design of the febrile surveillance protocol ensured high compliance in the trial. Maintaining engagement and access to healthcare beyond the protocol was important in improving febrile case evaluation ≤5 days of fever onset.</p>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":" ","pages":"102840"},"PeriodicalIF":6.3,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of climate change on travel-related vector-borne diseases: A case study on dengue virus transmission","authors":"Ebrahim Abbasi","doi":"10.1016/j.tmaid.2025.102841","DOIUrl":"10.1016/j.tmaid.2025.102841","url":null,"abstract":"<div><h3>Introduction</h3><div>Climate change significantly affects global health, particularly through the increased transmission of vector-borne diseases like dengue fever. This study examines how climate change influences the geographical spread of <em>Aedes aegypti</em> mosquitoes, the main carriers of dengue, highlighting its implications for public health worldwide.</div></div><div><h3>Materials and methods</h3><div>This study employed a comprehensive approach to evaluate the effect of climate change on dengue transmission dynamics. It included environmental data analysis, mosquito population surveys, and dengue case reports. Remote sensing data was used to track changes in temperature, precipitation, and humidity in dengue-prone areas. Field surveys measured mosquito density, while molecular techniques assessed viral load in Aedes mosquitoes. Additionally, mathematical modeling predicted dengue's future spread under various climate scenarios.</div></div><div><h3>Results</h3><div>The findings indicate a significant correlation between rising temperatures, changing rainfall patterns, and the expansion of <em>Aedes aegypti</em> habitats, resulting in increased mosquito populations in previously non-endemic areas. This ecological shift is linked to a rise in dengue incidence in regions affected by climate change. Projections suggest a 25 % increase in dengue spread by 2050, especially in Southeast Asia, sub-Saharan Africa, and parts of South America.</div></div><div><h3>Discussion</h3><div>The study highlights the significant effects of climate change on mosquito distribution and the increasing rates of dengue fever. Warmer temperatures and altered rainfall patterns enhance mosquito growth and virus transmission, while global travel aids the spread of the virus. It emphasizes the necessity for early intervention strategies, including better surveillance, vector control, and adaptations to climate changes, to tackle future dengue transmission issues.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102841"},"PeriodicalIF":6.3,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infectious diseases prevention and vaccination in migrants in Latin America: The challenges of transit through the treacherous Darien gap, Panama","authors":"Alfonso J. Rodriguez-Morales ,&nbsp;María Camila Puerta-Arias ,&nbsp;Rola Husni ,&nbsp;Juan J. Montenegro-Idrogo ,&nbsp;Juan Pablo Escalera-Antezana ,&nbsp;Lucia E. Alvarado-Arnez ,&nbsp;D. Katterine Bonilla-Aldana ,&nbsp;German Camacho-Moreno ,&nbsp;Henry Mendoza ,&nbsp;Ivan Arturo Rodriguez-Sabogal ,&nbsp;Jose Millán-Oñate ,&nbsp;Gustavo Lopardo ,&nbsp;Octavio A. Arce ,&nbsp;Sergio Cimerman ,&nbsp;Tânia do Socorro Souza Chaves ,&nbsp;Tomas Orduna ,&nbsp;Susana Lloveras ,&nbsp;Maritza Cabrera ,&nbsp;Monica Thormann ,&nbsp;Yasemin Özsürekçi ,&nbsp;Jose A. Suarez","doi":"10.1016/j.tmaid.2025.102839","DOIUrl":"10.1016/j.tmaid.2025.102839","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102839"},"PeriodicalIF":6.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A preliminary analysis of hand disinfection use by travellers and their colonisation-risk with multi-resistant bacteria: A proof-of-concept study","authors":"Tobias Kaspers ,&nbsp;Cosima Berdin ,&nbsp;Thérèse Staub ,&nbsp;Barbara Gärtner ,&nbsp;Fabian Berger ,&nbsp;Alexander Halfmann ,&nbsp;Sören L. Becker ,&nbsp;Sophie Schneitler","doi":"10.1016/j.tmaid.2025.102837","DOIUrl":"10.1016/j.tmaid.2025.102837","url":null,"abstract":"<div><h3>Background</h3><div>International travellers have the potential to transmit multidrug-resistant bacteria. However, the role of hygiene measures during travel has yet to be investigated.</div></div><div><h3>Method</h3><div>Travellers were asked about their use of disinfectants and hygiene behaviour. Stool samples were analysed for Gram-negative multi-resistant bacteria (MDRO). These data were analysed, and a new MDRO risk map was developed and compared with data from existing literature.</div></div><div><h3>Result</h3><div>Of 214 travellers, 6 (2.8 %) tested positive for an MDRO before and 16 (7.5 %) after the trip, with travel in known high-risk MDRO areas. Most travellers, 174 (81.3 %), regularly used disinfectants; only 36 (16.8 %) did not. There was no statistically significant correlation between the use of a disinfectant and colonisation with MDRO. In our and comparable studies, a high-risk region on the risk map was associated with an increased number of MDRO or extended-spectrum beta-lactamase (ESBL) positive returns.</div></div><div><h3>Conclusion</h3><div>Travellers showed a high willingness to use disinfectants. This preliminary study highlights the need for larger, randomized studies to better assess the true impact of hand disinfectants on MDRO acquisition.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102837"},"PeriodicalIF":6.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imported fever in returning travellers and migrants in Spain, 2009–2021. Analysis by the +REDIVI network","authors":"Pedro Guevara-Hernández ,&nbsp;Jara Llenas-García ,&nbsp;Marta Díaz-Menéndez ,&nbsp;Nuria Serre-Delcor ,&nbsp;Clara Crespillo-Andújar ,&nbsp;Fernando Salvador ,&nbsp;José Manuel Ruiz-Giardin ,&nbsp;Josune Goikoetxea-Agirre ,&nbsp;Diego Torrús-Tendero ,&nbsp;Fernando de la Calle-Prieto ,&nbsp;Inés Oliveira-Souto ,&nbsp;Pau Bosch-Nicolau ,&nbsp;Philip Wikman ,&nbsp;José A. Pérez-Molina ,&nbsp;the +Redivi study group","doi":"10.1016/j.tmaid.2025.102833","DOIUrl":"10.1016/j.tmaid.2025.102833","url":null,"abstract":"<div><h3>Background</h3><div>Travellers and migrants commonly present to health services with febrile syndrome, which can have different causes, including some that are life-threatening. A better understanding of these causes may help guide management and determine appropriate empirical treatments.</div></div><div><h3>Objectives</h3><div>The aim was to identify the leading causes of fever and to assess their association with the region of travel and type of travellers.</div></div><div><h3>Methods</h3><div>This prospective, multicentre study was conducted within the +REDIVI network. Data were collected on febrile syndrome cases among migrants, travellers, and people visiting friends and relatives (VFRs) from 2009 to 2021. Comparative analyses were performed according to patient categories and regions of travel/origin.</div></div><div><h3>Results</h3><div>Of the 4186 patients with febrile syndrome, the most frequent diagnosis was malaria (31.0 %), followed by dengue fever (12.0 %) and nonspecific fever of less than three weeks’ duration (11.6 %). Malaria predominated in people coming from sub-Saharan Africa (58.4 %), while dengue fever was more common in the rest of the regions (19.0 % in South America, 25.0 % in Central America and the Caribbean, 34.2 % in Southeast Asia, and 18.1 % in South-Central Asia). By type of traveller, tuberculosis was more frequent in migrants, malaria in VFRs, and dengue and other arboviral infections in travellers and VFRs.</div></div><div><h3>Conclusions</h3><div>Geographical area of travel and type of traveller are the main determinants of imported fever aetiology. Malaria remains the most common cause of febrile syndrome, especially in VFRs from sub-Saharan Africa, while dengue fever prevails in the other tropical regions.</div></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"65 ","pages":"Article 102833"},"PeriodicalIF":6.3,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}