Travel Medicine and Infectious Disease最新文献

{"title":"Travel medicine in Basel - 450 years before CISTM18","authors":"Irmgard L. Bauer","doi":"10.1016/j.tmaid.2024.102720","DOIUrl":"https://doi.org/10.1016/j.tmaid.2024.102720","url":null,"abstract":"<div><p>Concern for travellers' wellbeing and safety is as old as humankind. Historic documents offer insights into how a safe journey was prepared or travel ailments treated based on the prevailing knowledge of body and (dys)function. In 1561, Guilhelmo Gratarolo published a comprehensive book on what we call today ‘travel medicine’. Many then problems are still today's travel malaises. How they were dealt with 450 years ago is uncovered in his fascinating publication.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102720"},"PeriodicalIF":12.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000346/pdfft?md5=12c00a9ce0f4f5c6fcf542499e3f3953&pid=1-s2.0-S1477893924000346-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140535955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mpox across countries from Central and Eastern Europe - 2022 outbreak","authors":"Irina Ianache ,&nbsp;Agata Skrzat-Klapaczynska ,&nbsp;David Jilich ,&nbsp;Lukas Fleischhans ,&nbsp;Ivana Gmizic ,&nbsp;Jovan Ranin ,&nbsp;Antonios Papadopoulos ,&nbsp;Konstantinos Protopapas ,&nbsp;Velida Mulabdic ,&nbsp;Botond Lakatos ,&nbsp;Eva Livia Nagy ,&nbsp;Josip Begovac ,&nbsp;Tiberiu Holban ,&nbsp;Dilek Yildiz Sevgi ,&nbsp;Alma Cicic ,&nbsp;Nina Yancheva ,&nbsp;Lubomir Sojak ,&nbsp;Nino Rukhadze ,&nbsp;Justyna Kowalska ,&nbsp;Cristiana Oprea","doi":"10.1016/j.tmaid.2024.102719","DOIUrl":"https://doi.org/10.1016/j.tmaid.2024.102719","url":null,"abstract":"<div><h3>Background</h3><p>The aim of the study was to assess socio-demographical characteristics, clinical presentation, and outcomes in patients diagnosed with mpox.</p></div><div><h3>Methods</h3><p>A survey on patients diagnosed with mpox was performed in 14 countries from Central and Eastern Europe. Data was compared according to HIV status and country of origin (EU vs. non-EU). Mpox diagnosis was confirmed by RT-PCR from oropharyngeal swabs, skin lesions, and other body fluids.</p></div><div><h3>Results</h3><p>Out of 154 patients confirmed with mpox in 2022, 99.3% were males, with a median age (years) of 35 (IQR 30–39), 90.2% MSM and 48.7% PLWH. Compared to HIV-negative subjects, PLWH had more frequent high-risk behaviours:chemsex (p = 0.015), group sex (p = 0.027), and a history of sexually transmitted infections (STIs) (p = 0.004). Persons from EU were more often PLWH (p = 0.042), MSM (p &lt; 0.0001), had multiple sexual partners (p = 0.025), practiced chemsex (p = 0.008) or group-sex (p = 0.005) and had more often history of STIs (p &lt; 0.0001). The median CD4 cell count/mL at mpox diagnosis was 713 (IQR 486–996) and 73.5% had undetectable HIV VL. The commonest clinical features were fever (108 cases), lymphadenopathy (78), and vesiculo-pustular rash: penile (76), perianal (48), limbs (67). Fifty-one (31%) persons were hospitalized due to complications or epidemiological reasons. Three patients received tecovirimat or cidofovir. The outcome was favorable for all patients, including 4 with severe forms.</p></div><div><h3>Conclusions</h3><p>Mpox was diagnosed predominantly in young MSM, with high-risk behaviors and history of STIs. Effective contact tracing and vaccination are important strategic pillars to control mpox outbreaks.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102719"},"PeriodicalIF":12.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000334/pdfft?md5=9d886ddc4897f3065cabcba454750587&pid=1-s2.0-S1477893924000334-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140350869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamics of viral DNA shedding and culture viral DNA positivity in different clinical samples collected during the 2022 mpox outbreak in Lombardy, Italy","authors":"Antonio Piralla ,&nbsp;Davide Mileto ,&nbsp;Alberto Rizzo ,&nbsp;Guglielmo Ferrari ,&nbsp;Federica Giardina ,&nbsp;Stefano Gaiarsa ,&nbsp;Greta Petazzoni ,&nbsp;Micol Bianchi ,&nbsp;Federica Salari ,&nbsp;Fiorenza Bracchitta ,&nbsp;Josè Camilla Sammartino ,&nbsp;Alessandro Ferrari ,&nbsp;Gloria Gagliardi ,&nbsp;Alessandro Mancon ,&nbsp;Claudio Fenizia ,&nbsp;Mara Biasin ,&nbsp;Francesca Rovida ,&nbsp;Stefania Paolucci ,&nbsp;Elena Percivalle ,&nbsp;Alessandra Lombardi ,&nbsp;Sara Piccinelli","doi":"10.1016/j.tmaid.2024.102698","DOIUrl":"10.1016/j.tmaid.2024.102698","url":null,"abstract":"<div><h3>Background</h3><p>Mpox virus (MPXV) has recently spread outside of sub-Saharan Africa. This large multicentre study was conducted in Lombardy, the most densely populated Italian region accounting for more than 40% of Italian cases. The present study aims to: i) evaluate the presence and the shedding duration of MPXV DNA in different body compartments correlating the MPXV viability with the time to onset of symptoms; ii) provide evidence of MPXV persistence in different body compartment as a source of infection and iii) characterize the MPXV evolution by whole genome sequencing (WGS) during the outbreak occurred in Italy.</p></div><div><h3>Material and methods</h3><p>The study included 353 patients with a laboratory-confirmed diagnosis of MPXV infection screened in several clinical specimens in the period May 24th - September 1st, 2022. Viral isolation was attempted from different biological matrices and complete genome sequencing was performed for 61 MPXV strains.</p></div><div><h3>Results</h3><p>MPXV DNA detection was more frequent in the skin (94.4%) with the longest median time of viral clearance (16 days). The actively-replicating virus in cell culture was obtained for 123/377 (32.6%) samples with a significant higher viral quantity on isolation positive samples (20 vs 31, p &lt; 0.001). The phylogenetic analysis highlighted the high genetic identity of the MPXV strains collected, both globally and within the Lombardy region.</p></div><div><h3>Conclusion</h3><p>Skin lesion is gold standard material and the high viral load and the actively-replicating virus observed in genital sites confirms that sexual contact plays a key role in the viral transmission.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102698"},"PeriodicalIF":12.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000127/pdfft?md5=7cf5e2d73167e755ec0b01a8ae144bde&pid=1-s2.0-S1477893924000127-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140331995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatitis and secondary dengue infection in Reunion island","authors":"Antoine Alvarez,&nbsp;Olivier Maillard,&nbsp;Yves-Marie Diarra,&nbsp;Antoine Bertolotti,&nbsp;Patrick Gérardin","doi":"10.1016/j.tmaid.2024.102717","DOIUrl":"10.1016/j.tmaid.2024.102717","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102717"},"PeriodicalIF":12.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000310/pdfft?md5=dc8e22967a00c952e3718a99cafed6e6&pid=1-s2.0-S1477893924000310-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140327201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous intestinal perforation due to a possible infection due to Angiostrongylus costaricensis in Colombia","authors":"Paola Marsela Pérez-Camacho ,&nbsp;Jaime A. Patiño-Niño ,&nbsp;Alejandro Restrepo Cedeño ,&nbsp;Inés Elvira Gómez ,&nbsp;Lina M. Sandoval-Calle","doi":"10.1016/j.tmaid.2024.102706","DOIUrl":"10.1016/j.tmaid.2024.102706","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102706"},"PeriodicalIF":12.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000206/pdfft?md5=2044892878adfff9d7898fccc5c5e898&pid=1-s2.0-S1477893924000206-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical hand foot and mouth disease related Coxsackievirus-A10 infection in an adult patient","authors":"Giulia Ciccarese,&nbsp;Francesco Broccolo,&nbsp;Cristian Fidanzi,&nbsp;Gaetano Serviddio,&nbsp;Francesco Drago","doi":"10.1016/j.tmaid.2024.102716","DOIUrl":"10.1016/j.tmaid.2024.102716","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102716"},"PeriodicalIF":12.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000309/pdfft?md5=7419ca6a9b71368241e9f2e4161caeea&pid=1-s2.0-S1477893924000309-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immune thrombocytopenia occurs in an aplastic anemia patient infected with scrub typhus in China","authors":"Jingyi Xin,&nbsp;Bingke Zhu,&nbsp;Haiping Yang","doi":"10.1016/j.tmaid.2024.102715","DOIUrl":"10.1016/j.tmaid.2024.102715","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102715"},"PeriodicalIF":12.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000292/pdfft?md5=a798649f674aa3d9a0bc4a338a6523c7&pid=1-s2.0-S1477893924000292-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140190176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serological evidence of louse-borne relapsing fever in northern Kenya","authors":"Flavia Reyer ,&nbsp;Martyna Olesiuk ,&nbsp;Florian Röttgerding ,&nbsp;Volker Fingerle ,&nbsp;Abdulrahman Adamu ,&nbsp;Dan Waithiru ,&nbsp;John Njeru ,&nbsp;Peter Kraiczy","doi":"10.1016/j.tmaid.2024.102714","DOIUrl":"10.1016/j.tmaid.2024.102714","url":null,"abstract":"<div><h3>Background</h3><p>Tick- and louse-borne relapsing fever are highly-neglected, vector-borne diseases caused by diverse <em>Borrelia</em> species. Presently, there are no data available on the endemicity of tick- and louse-borne relapsing fever spirochetes in Kenya. Here, we present data of a retrospective study on the seroprevalence of louse-borne relapsing fever (LBRF) in northern Kenya.</p></div><div><h3>Methods</h3><p>A novel immunoassay, recently established for the diagnosis of LBRF was utilized to screen 2005 blood samples collected from individuals with fever without a source in Turkana County, Kenya between May 2009 and November 2010 for anti-LBRF antibodies.</p></div><div><h3>Results</h3><p>Out of the 2005 sera analyzed, 287 samples (14.3 %) were considered anti-LBRF IgG positive. Subsequent analyses revealed that 87 out of 152 sera randomly selected from these 2005 samples were tested positive (57.2 %) for anti-LBRF IgM antibodies. Most of the IgG and IgM positive samples were from individuals living in northern regions of Turkana County.</p></div><div><h3>Conclusion</h3><p>Our serological finding provides strong evidence for the occurrence of LBRF in Kenya.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102714"},"PeriodicalIF":12.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000280/pdfft?md5=da6decbd88ee82aea40f1bb89f178d8c&pid=1-s2.0-S1477893924000280-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal","authors":"Ihssane Ouaddane ,&nbsp;Ndiaw Goumballa ,&nbsp;Xuan Duong Tran ,&nbsp;Coumba Diouf ,&nbsp;Seydina M. Diene ,&nbsp;Jean-Marc Rolain ,&nbsp;Cheikh Sokhna ,&nbsp;Philippe Gautret","doi":"10.1016/j.tmaid.2024.102709","DOIUrl":"10.1016/j.tmaid.2024.102709","url":null,"abstract":"<div><h3>Background</h3><p>The Grand Magal of Touba (GMT) associates with risks of infection, but no study on the circulation of resistant bacteria has yet been conducted.</p></div><div><h3>Materials and methods</h3><p>qPCR was performed on rectal samples from GMT pilgrims between 2018 and 2021, before and after their participation in the gathering. Rectal samples from between 2018 and 2020 were also cultured on specific media, and antibiotic susceptibility testing was performed.</p></div><div><h3>Results</h3><p>Forty-one of the 296 (13.8%) pilgrims had at least one gastrointestinal symptom and 91/290 (31.4%) acquired pathogenic bacteria, mostly <em>Escherichia coli</em>. A total of 54.7% of pilgrims reported washing their hands more frequently than usual and 89.2% used soap. One hundred and five (36.2%) acquired at least one resistance gene, notably CTX-M A (21.0%), SHV (16.5%) and TEM (8.2%). The strains isolated by culture were mostly <em>E. coli</em>. These bacteria were found to be sensitive to carbapenems and resistant to amoxicillin and amoxicillin-clavulanic acid. The acquisition of enteroaggregative <em>E. coli</em> was independently associated with CTX-M A and TEM acquisition.</p></div><div><h3>Conclusion</h3><p>Pilgrims presented a risk for acquisition of CTX-M A after the GMT. Surveillance of the prevalence of resistant bacteria and the occurrence of associated clinical infections among pilgrims are necessary in the future.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102709"},"PeriodicalIF":12.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000231/pdfft?md5=a745849fc8e53214b9db26118ca5d7f8&pid=1-s2.0-S1477893924000231-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140120743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imported infectious diseases in migrants from Latin America: A retrospective study from a referral centre for tropical diseases in Spain, 2017–2022","authors":"Marta Arsuaga ,&nbsp;Rosa De Miguel Buckley ,&nbsp;Fernando De La Calle-Prieto ,&nbsp;Marta Díaz-Menéndez","doi":"10.1016/j.tmaid.2024.102708","DOIUrl":"10.1016/j.tmaid.2024.102708","url":null,"abstract":"<div><h3>Introduction</h3><p>Detecting imported diseases by migrants and individuals visiting friends and relatives (VFR) is key in the prevention and management of emergent infectious diseases acquired abroad.</p></div><div><h3>Methods</h3><p>Retrospective descriptive study on migrants and VFR from Central and South America between 2017 and 2022 attended at a National Referral Centre for Tropical Diseases in Madrid, Spain. Demographic characteristics, syndromes and confirmed travel-related diagnoses were obtained from hospital patient medical records.</p></div><div><h3>Results</h3><p>1654 cases were registered, median age of 42 years, 69.1% were female, and 55.2% were migrants. Most cases came from Bolivia (49.6%), followed by Ecuador (12.9%). Health screening while asymptomatic (31.6%) was the main reason for consultation, followed by Chagas disease follow-up (31%). Of those asymptomatic at screening, 47,2% were finally diagnosed of any disease, mainly Chagas disease (19,7%) and strongyloidiasis (10,2%)</p></div><div><h3>Conclusion</h3><p>Our study emphasizes the importance of proactive health screening to detect asymptomatic conditions in migrants and VFR, enabling timely intervention and improved health outcomes. By understanding the unique health profiles of immigrant populations, targeted public health interventions can be devised to safeguard the well-being of these vulnerable groups.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"59 ","pages":"Article 102708"},"PeriodicalIF":12.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S147789392400022X/pdfft?md5=1594aa7be6f81512ef09f7e760894cc4&pid=1-s2.0-S147789392400022X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140102499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}