Travel Medicine and Infectious Disease最新文献

{"title":"Imported schistosomiasis in travelers: Experience from a referral tropical medicine unit in Barcelona, Spain","authors":"","doi":"10.1016/j.tmaid.2024.102742","DOIUrl":"10.1016/j.tmaid.2024.102742","url":null,"abstract":"<div><h3>Background</h3><p>Acute schistosomiasis occurs most often in travelers to endemic regions. The aim of the study is to describe the epidemiological, clinical and parasitological characteristics of patients with schistosomiasis acquired during an international travel.</p></div><div><h3>Methods</h3><p>Observational retrospective study including all travel-related schistosomiasis cases seen at the International Health Unit Vall d’Hebron-Drassanes (Barcelona, Spain) from 2009 to 2022. Diagnosis of schistosomiasis was defined by the presence of <em>Schistosoma</em> eggs in stools or urine or the positivity of a serological test. We collected demographic, epidemiological, clinical, parasitological, and therapeutic information.</p></div><div><h3>Results</h3><p>917 cases of schistosomiasis were diagnosed, from whom 96 (10.5 %) were travel-related. Mean age of the patients was 34.9 years, and 53.1 % were women. Median duration of the travel was 72 days, and geographical areas where travelers had contact with fresh water were Africa (82.3 %), Asia (12.5 %), and South America (5.2 %). Twenty (20.8 %) patients reported having had some clinical symptom, being gastrointestinal symptoms the most frequent. Two patients developed the classical Katayama syndrome. In eleven (11.5 %) cases eggs were observed in urine or feces samples, and 85 (88.5 %) cases were diagnosed by a positive serology. Ninety-one (94.8 %) patients received treatment with praziquantel with different therapeutic schemes. The two patients with Katayama syndrome received concomitant treatment with corticosteroids.</p></div><div><h3>Conclusions</h3><p>Schistosomiasis in travelers represented 10 % of the overall schistosomiasis cases in our center. Increasing the awareness in the pre-travel advice and implementing specific screening in those travelers at risk (long travelers, contact with fresh water) could reduce the incidence and associated morbidity in this group.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"60 ","pages":"Article 102742"},"PeriodicalIF":6.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000589/pdfft?md5=ae185c2b3f4a450a9e6910ca0e158836&pid=1-s2.0-S1477893924000589-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141601878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of travel-associated infection with melioidosis pneumonia and septicemia","authors":"Li Yuan,&nbsp;Si-Min Huang,&nbsp;Jia-Hao Yang,&nbsp;Qiang Qu,&nbsp;Ying Liu,&nbsp;Yi-Wen Xiao,&nbsp;Jian Qu","doi":"10.1016/j.tmaid.2024.102743","DOIUrl":"10.1016/j.tmaid.2024.102743","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"60 ","pages":"Article 102743"},"PeriodicalIF":6.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000590/pdfft?md5=8c79411722e9adde35239ad9e130a5e7&pid=1-s2.0-S1477893924000590-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141724586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Now is the time to set up formal forums for clinical advice with emerging and zoonotic infections: A shared experience","authors":"Stephen D. Woolley,&nbsp;Jeremy Nel,&nbsp;Jacqueline Weyer,&nbsp;Anne Neary,&nbsp;Lucille Blumberg,&nbsp;Michael BJ. Beadsworth,&nbsp;NHS England Airborne High Consequence Infectious Diseases Network","doi":"10.1016/j.tmaid.2024.102738","DOIUrl":"10.1016/j.tmaid.2024.102738","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"60 ","pages":"Article 102738"},"PeriodicalIF":6.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000541/pdfft?md5=6501555bbccf0b3a2150c262d33d58df&pid=1-s2.0-S1477893924000541-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141601881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical profile and management of a Spanish single-center retrospective cohort of patients with post-chikungunya associated complications.","authors":"Fernando de la Calle-Prieto, Juan J Barriga, Marta Arsuaga, Rosa de Miguel, Marta Díaz-Menéndez","doi":"10.1016/j.tmaid.2024.102726","DOIUrl":"10.1016/j.tmaid.2024.102726","url":null,"abstract":"<p><strong>Background: </strong>This study aims to describe post-chikungunya complications chronically developed cases in returning travelers from some epidemic/endemic regions, and the variables that are associated with the progression of acute or subacute cases to the chronic phase.</p><p><strong>Methods: </strong>This single-center retrospective cohort study included chikungunya fever cases treated at La Paz-Carlos III University Hospital in Madrid, Spain, April 2014 to September 2016, when the chikungunya outbreak in Latin America started through the time of its greatest impact.</p><p><strong>Results: </strong>The analysis included 119 cases. Of these, 67.2 % were male, with a median age of 41.0 years [IQR 16.0 to 76.0] years. Only 25.6 % of the patients attended a pre-travel advice consultation. Most patients reported arthralgias, which significantly impacted their daily quality of life (86 %). The mean duration of joint symptoms was 129.4 days, with a median of 90 days [IQR 0 to 715]. Factors found to be associated with chronic arthralgia include female sex, country of infection, age at diagnosis, previous diseases, symptoms during the acute phase, pain in previously injured tendons/joints, acute phase severity, and various laboratory markers such as hemoglobin, hematocrit, total serum bilirubin, and creatinine. Progression to chronic arthralgia significantly increased the need for changes in daily activity. Furthermore, 42.6 % of patients with chronic arthralgia reported recurrence of symptoms once they felt they had disappeared. Targeted treatment regimens led to significant improvements in these patients.</p><p><strong>Conclusions: </strong>The results of this study underscore the need for: (1) comprehensive pre-travel advice; (2) effective management of patients in specialized units, alongside early diagnosis and treatment, to prevent trivialization of these viral infections; and (3) the development of interdisciplinary recommendations to assist physicians in treating patients and enhancing outcomes.</p>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":" ","pages":"102726"},"PeriodicalIF":6.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunogenicity of 4-dose Essen intramuscular regimen for rabies post-exposure prophylaxis: A multi-center cross-sectional study in China","authors":"Qisheng Hou ,&nbsp;Si Liu ,&nbsp;Cheng Liu ,&nbsp;Xu Wang ,&nbsp;Jirong Shi ,&nbsp;Qingjun Chen ,&nbsp;Xinjun Lv ,&nbsp;Zhenggang Zhu ,&nbsp;Chuanlin Wang ,&nbsp;Wenwu Yin","doi":"10.1016/j.tmaid.2024.102735","DOIUrl":"10.1016/j.tmaid.2024.102735","url":null,"abstract":"<div><h3>Background</h3><p>The 4-dose Essen intramuscular (IM) regimen for rabies post-exposure prophylaxis (PEP) has been recommended by Advisory Committee on Immunization Practices (ACIP) and World Health Organization (WHO), but the large-sample clinical evidence is still limited.</p></div><div><h3>Method</h3><p>Rabies virus neutralizing antibodies of 11,752 patients were detected from 409 rabies prevention clinics in 27 provinces in China. Patients with serum collected before or no later than 1 h after injection on the day of the fifth dose (day 28) of 5-dose Essen regimen were included in Group A to observe the immune efficacy of 4-dose Essen IM regimen, and patients with serum collected 14–28 days after injection of the fifth dose were included in Group B to observe the immune efficacy of 5-dose Essen IM regimen.</p></div><div><h3>Results</h3><p>Finally, 2351 cases met the inclusion and exclusion criteria, including 2244 cases in Group A and 107 cases in Group B. The antibody titer of Group A was higher than that of Group B [12.21 (4.15, 32.10) IU/ml <em>vs.</em> 9.41 (3.87, 27.38) IU/ml] (<em>P</em> = 0.002). In Group A, the median antibody titers were 4.01IU/ml, 11.63IU/ml and 29.46IU/ml in patients vaccinated with purified hamster kidney cell vaccine (PHKCV), purified Vero cell vaccine (PVRV), and human diploid cell rabies vaccine (HDCV), respectively, with statistical significance (<em>P</em> &lt; 0.001).</p></div><div><h3>Conclusions</h3><p>The 4-dose Essen IM regimen could provide satisfactory immune effect, and HDCV induced higher antibody titer than PHKCV or PVRV.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"60 ","pages":"Article 102735"},"PeriodicalIF":6.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000516/pdfft?md5=8b2fe93044c079ef9915e86c4cd6a62a&pid=1-s2.0-S1477893924000516-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141591488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling approaches to inform travel-related policies for COVID-19 containment: A scoping review and future directions","authors":"","doi":"10.1016/j.tmaid.2024.102730","DOIUrl":"10.1016/j.tmaid.2024.102730","url":null,"abstract":"<div><h3>Background</h3><p>Travel-related strategies to reduce the spread of COVID-19 evolved rapidly in response to changes in the understanding of SARS-CoV-2 and newly available tools for prevention, diagnosis, and treatment. Modeling is an important methodology to investigate the range of outcomes that could occur from different disease containment strategies.</p></div><div><h3>Methods</h3><p>We examined 43 articles published from December 2019 through September 2022 that used modeling to evaluate travel-related COVID-19 containment strategies. We extracted and synthesized data regarding study objectives, methods, outcomes, populations, settings, strategies, and costs. We used a standardized approach to evaluate each analysis according to 26 criteria for modeling quality and rigor.</p></div><div><h3>Results</h3><p>The most frequent approaches included compartmental modeling to examine quarantine, isolation, or testing. Early in the pandemic, the goal was to prevent travel-related COVID-19 cases with a focus on individual-level outcomes and assessing strategies such as travel restrictions, quarantine without testing, social distancing, and on-arrival PCR testing. After the development of diagnostic tests and vaccines, modeling studies projected population-level outcomes and investigated these tools to limit COVID-19 spread. Very few published studies included rapid antigen screening strategies, costs, explicit model calibration, or critical evaluation of the modeling approaches.</p></div><div><h3>Conclusion</h3><p>Future modeling analyses should leverage open-source data, improve the transparency of modeling methods, incorporate newly available prevention, diagnostics, and treatments, and include costs and cost-effectiveness so that modeling analyses can be informative to address future SARS-CoV-2 variants of concern and other emerging infectious diseases (e.g., mpox and Ebola) for travel-related health policies.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"62 ","pages":"Article 102730"},"PeriodicalIF":6.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000449/pdfft?md5=977e426567d9449636030bd5c7e32e81&pid=1-s2.0-S1477893924000449-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do not forget mpox!","authors":"Luca Pipitò,&nbsp;Marcello Trizzino,&nbsp;Donatella Ferraro,&nbsp;Cinzia Calà,&nbsp;Giovanni Giammanco,&nbsp;Antonio Cascio","doi":"10.1016/j.tmaid.2024.102728","DOIUrl":"10.1016/j.tmaid.2024.102728","url":null,"abstract":"","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"60 ","pages":"Article 102728"},"PeriodicalIF":12.0,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000425/pdfft?md5=392ef594bf6dd61adff92af602edf60f&pid=1-s2.0-S1477893924000425-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Might procalcitonin help predict imported falciparum malaria in children?","authors":"Alexandra Tielli ,&nbsp;Rachidou Ouorou ,&nbsp;Lauren Pull ,&nbsp;Karamo Souare ,&nbsp;Olivier Bouchaud ,&nbsp;Laurent Brutus ,&nbsp;Frédérick Gay ,&nbsp;Jean-Yves Siriez","doi":"10.1016/j.tmaid.2024.102731","DOIUrl":"10.1016/j.tmaid.2024.102731","url":null,"abstract":"<div><h3>Background</h3><p>Procalcitonin (PCT) has been proposed as a marker for malaria severity in adults, with a threshold of 10 ng/ml for severe falciparum disease. Whether PCT is useful in children is debated.</p></div><div><h3>Patients &amp; methods</h3><p>A retrospective case-control study was conducted to compare initial PCT levels in children with uncomplicated malaria and a control group, and between children with uncomplicated and severe malaria.</p></div><div><h3>Results</h3><p>Results showed significantly higher PCT levels in malaria cases compared to the control group and in malaria severe cases compared to uncomplicated cases. A Receiving Operator Characteristic curve established a PCT threshold of 0.65 ng/ml with a negative predictive value of 98.8 % based on a prevalence of 10 %. Analyzing the pooled results of five studies suggested a threshold of 6.17 ng/ml for differentiating uncomplicated and severe malaria.</p></div><div><h3>Conclusion</h3><p>PCT might be a useful tool to help rule out malaria and predict potential disease severity in returning travelers.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"60 ","pages":"Article 102731"},"PeriodicalIF":12.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000450/pdfft?md5=5a37051faa51775e856def594f4b884a&pid=1-s2.0-S1477893924000450-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141184770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening and early detection of communicable diseases on board cruise ships: An assessment of passengers’ preferences on technical solutions","authors":"Christina Golna ,&nbsp;Ioannis Anestis Markakis ,&nbsp;Chara Tzavara ,&nbsp;Pavlos Golnas ,&nbsp;Aikaterini Ntokou ,&nbsp;Kyriakos Souliotis","doi":"10.1016/j.tmaid.2024.102729","DOIUrl":"10.1016/j.tmaid.2024.102729","url":null,"abstract":"<div><h3>Background</h3><p>Implementing technological solutions to screen for and detect early the most prevalent communicable diseases on cruise ships is contingent on, among others, willingness of passengers to accept use of such solutions.</p></div><div><h3>Method</h3><p>We surveyed passenger preferences to record their willingness to accept technological solutions for screening and early detection of communicable diseases on cruise ships. Self-reported sociodemographic characteristics, use of technology and acceptance of solutions were recorded anonymously in paper format. Multiple logistic regression analyses investigated the association of demographic and other characteristics with willingness and barriers/concerns of passengers to endorse proposed solutions.</p></div><div><h3>Results</h3><p>Of a total of 1344 passengers on two successive cruises on board CELESTYAL OLYMPIA, 336 (1 every 4) participated in the survey. The vast majority of passengers (92.3 %, n = 310) agreed with at least one solution. Passengers showed lower levels of acceptance for more personalized solutions, such as use of wearable devices (45.5 %) and monitoring with cameras (64.0 %), whereas they were more receptive to less personally invasive solutions, such as integration of cabins with air purifiers (89.6 %) and air quality sensors (80.4 %). Age, self-employment status, educational level, and fear of contacting a communicable disease were significantly correlated with passengers’ willingness to adopt proposed solutions.</p></div><div><h3>Conclusions</h3><p>To successfully integrate screening and early detection technological solutions in cruise ships, it is imperative that targeted awareness and education interventions are implemented on passengers to strengthen understanding and acceptance of such solutions and assuage concerns around monitoring and handling of personal health data.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"60 ","pages":"Article 102729"},"PeriodicalIF":12.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000437/pdfft?md5=c673e33d36e6d64ff0b6c7b788dcb256&pid=1-s2.0-S1477893924000437-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141184773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy outcomes in women with imported malaria in mainland France: A retrospective study from 2004 to 2014","authors":"P. Imbert ,&nbsp;J. Nizard ,&nbsp;G. Werkoff ,&nbsp;E. Kendjo ,&nbsp;C. Ficko ,&nbsp;M. Thellier ,&nbsp;for the “PALUFEN Group”","doi":"10.1016/j.tmaid.2024.102727","DOIUrl":"10.1016/j.tmaid.2024.102727","url":null,"abstract":"<div><h3>Objectives</h3><p>There is little data on pregnant women with imported malaria in high-income countries, especially regarding offspring outcomes. We wanted to determine pregnancy outcomes of imported malaria in pregnant women in mainland France.</p></div><div><h3>Patients and methods</h3><p>We conducted a retrospective, descriptive study of outcomes in pregnant women hospitalized with malaria from 2004 to 2014 in two regions of mainland France. An adverse outcome was defined as a miscarriage, stillbirth, preterm birth (&lt;35 weeks of gestation), low birth weight (LBW) defined as less than 2500 g, or congenital malaria.</p></div><div><h3>Results</h3><p>Of 60 pregnancies, 5 were excluded because of elective abortions; 55 were investigated, of which 11 were primigravidae and 44 multigravidae. Pregnancies were singleton (n = 51) or twin (n = 4). Mean age was 30.4 years (range:19–45 y). Among the 55 cases, 9 ended in a miscarriage (8 singletons and 1 twin pregnancy) and 1 had a stillbirth at 21 weeks of gestation, all immediately after the malarial episode. 45 gave birth (29 vaginal deliveries and 16 caesarean sections) to 48 (42 singletons and 6 twins) newborns. Amongst these, 30 were healthy full-term newborns, 10 had LBW, and 8 were preterm. Overall, 26 of 55 (47.3%) pregnancies, and 29 of 59 (49.2%) offsprings had adverse outcomes. Compared to singleton pregnancies, twin pregnancies were associated with adverse outcomes (p = 0.0438).</p></div><div><h3>Conclusions</h3><p>Imported malaria has a severe impact on pregnancy outcomes. Prevention and management of imported malaria in pregnancy should be optimized.</p></div>","PeriodicalId":23312,"journal":{"name":"Travel Medicine and Infectious Disease","volume":"60 ","pages":"Article 102727"},"PeriodicalIF":12.0,"publicationDate":"2024-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1477893924000413/pdfft?md5=23ddd735e5b4326d5f46d3936cc64f61&pid=1-s2.0-S1477893924000413-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141071588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}