Demographic, epidemiological and clinical characteristics of Ukrainian war refugees with HIV infection in the Slovak Republic

IF 6.3 3区医学 Q1 INFECTIOUS DISEASES

Travel Medicine and Infectious Disease Pub Date : 2024-09-27 DOI:10.1016/j.tmaid.2024.102764

Ricardo Massmann , Kristína Doležalová (Mgr) , Lubomír Soják , Olena Samsonová , Danica Valkovičová Staneková , Ondrej Zahornacký , Pavol Jarčuška , Mária Záriš Vachalíková , Diana Vološinová , Ľubica Piesecká , Veronika Vahalová , Katarína Šimeková , Terézia Smiešková , Alexandra Bražinová , Ivy Kigen , Marek Malý , Ladislav Machala

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引用次数: 0

Abstract

Background

The Slovak Republic, an Eastern European country, borders Ukraine, which has one of the highest rates of HIV/AIDS in Europe. This study aims to inform readers about the demographic characteristics of Ukrainian war refugees with HIV/AIDS seeking temporary protection status in Slovakia due to the Russian invasion of February 24, 2022. It focuses on their epidemiology, immunological profiles, co-infections, and treatment.

Design

Multicenter, retrospective study between March 1, 2022, and March 31, 2023.

Methods

Data were collected from all Ukrainian patients with refugee status living with HIV or newly diagnosed, who presented to any of the five HIV/AIDS centers in Slovakia. Information was obtained through medical interviews, physical examinations, laboratory tests and medical reports from the Ukrainian Ministry of Health.

Results

From March 1, 2022, to March 31, 2023, 141 Ukrainian refugees were included, mostly women (56.7 %, n = 80), with a median age of 41 years. The median CD4⁺ count was 680 cells/mL; 69.2 % (n = 97) had a viral load below 40 copies/mL. On arrival, 87.8 % (n = 123) were on ART, 90.2 % (n = 111) on dolutegravir. Coinfections included hepatitis C (31 %, n = 41), hepatitis B (12.5 %, n = 17), and tuberculosis (11.3 %, n = 16). Three died from AIDS complications.

Conclusion

The study provides a detailed overview of the epidemiological, demographic, immunological, co-infection, and treatment characteristics of Ukrainian PLWHA displaced by the war to the Slovak republic. With the conflict ongoing, it is necessary to be prepared for more refugees in the coming months.

查看原文本刊更多论文

斯洛伐克共和国感染艾滋病毒的乌克兰战争难民的人口、流行病学和临床特征。

背景：斯洛伐克共和国是一个东欧国家，与乌克兰接壤，而乌克兰是欧洲艾滋病毒/艾滋病感染率最高的国家之一。本研究旨在向读者介绍因 2022 年 2 月 24 日俄罗斯入侵而在斯洛伐克寻求临时保护身份的感染艾滋病毒/艾滋病的乌克兰战争难民的人口特征。研究重点是他们的流行病学、免疫学特征、合并感染和治疗情况：设计：2022 年 3 月 1 日至 2023 年 3 月 31 日期间的多中心回顾性研究：方法：收集所有在斯洛伐克五个艾滋病中心就诊的乌克兰难民身份艾滋病感染者或新确诊患者的数据。信息通过医学访谈、身体检查、实验室检测和乌克兰卫生部的医疗报告获得：从2022年3月1日至2023年3月31日，共纳入141名乌克兰难民，其中大部分为女性（56.7%，n=80），中位年龄为41岁。CD4+ 细胞计数中位数为 680 cells/mL；69.2%（n=97）的病毒载量低于 40 copies/mL。抵达时，87.8%（n=123）的患者正在接受抗逆转录病毒疗法，90.2%（n=111）的患者正在接受多鲁曲韦治疗。合并感染包括丙型肝炎（31%，n=41）、乙型肝炎（12.5%，n=17）和肺结核（11.3%，n=16）。3 人死于艾滋病并发症：这项研究详细概述了因战争而流落到斯洛伐克共和国的乌克兰 PLWHA 的流行病学、人口统计学、免疫学、合并感染和治疗特征。随着冲突的持续，有必要为未来几个月更多的难民做好准备。

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来源期刊

Travel Medicine and Infectious Disease PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECTIOUS DISEASES

CiteScore

19.40

自引率

1.70%

发文量

211

审稿时长

49 days

期刊介绍： Travel Medicine and Infectious Disease Publication Scope: Publishes original papers, reviews, and consensus papers Primary theme: infectious disease in the context of travel medicine Focus Areas: Epidemiology and surveillance of travel-related illness Prevention and treatment of travel-associated infections Malaria prevention and treatment Travellers' diarrhoea Infections associated with mass gatherings Migration-related infections Vaccines and vaccine-preventable disease Global policy/regulations for disease prevention and control Practical clinical issues for travel and tropical medicine practitioners Coverage: Addresses areas of controversy and debate in travel medicine Aims to inform guidelines and policy pertinent to travel medicine and the prevention of infectious disease Publication Features: Offers a fast peer-review process Provides early online publication of accepted manuscripts Aims to publish cutting-edge papers