旅行者手部消毒使用及其多耐药细菌定殖风险的初步分析：一项概念验证研究。

IF 6.3 3区医学 Q1 INFECTIOUS DISEASES

Travel Medicine and Infectious Disease Pub Date : 2025-03-17 DOI:10.1016/j.tmaid.2025.102837

Tobias Kaspers , Cosima Berdin , Thérèse Staub , Barbara Gärtner , Fabian Berger , Alexander Halfmann , Sören L. Becker , Sophie Schneitler

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引用次数: 0

摘要

背景：国际旅行者有可能传播耐多药细菌。然而，旅行中卫生措施的作用还有待调查。方法：对出境者进行消毒水使用情况和卫生行为调查。对粪便样本进行革兰氏阴性多重耐药菌（MDRO）检测。对这些数据进行分析，绘制新的MDRO风险图，并与现有文献的数据进行比较。结果：在214名旅行者中，6人（2.8%）在旅行前检测出MDRO阳性，16人（7.5%）在旅行后检测出MDRO阳性，并在已知的MDRO高风险地区旅行。大多数旅行者（174人）（81.3%）经常使用消毒剂；只有36个（16.8%）没有。消毒剂的使用与MDRO的定植之间没有统计学上的显著相关性。在我们的研究和类似的研究中，风险图上的高风险区域与MDRO或扩展谱β -内酰胺酶（ESBL）阳性回报的增加有关。结论：旅客使用消毒剂的意愿较高。这项初步研究强调需要进行更大规模的随机研究，以更好地评估手部消毒剂对MDRO获得的真正影响。

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A preliminary analysis of hand disinfection use by travellers and their colonisation-risk with multi-resistant bacteria: A proof-of-concept study

Background

International travellers have the potential to transmit multidrug-resistant bacteria. However, the role of hygiene measures during travel has yet to be investigated.

Method

Travellers were asked about their use of disinfectants and hygiene behaviour. Stool samples were analysed for Gram-negative multi-resistant bacteria (MDRO). These data were analysed, and a new MDRO risk map was developed and compared with data from existing literature.

Result

Of 214 travellers, 6 (2.8 %) tested positive for an MDRO before and 16 (7.5 %) after the trip, with travel in known high-risk MDRO areas. Most travellers, 174 (81.3 %), regularly used disinfectants; only 36 (16.8 %) did not. There was no statistically significant correlation between the use of a disinfectant and colonisation with MDRO. In our and comparable studies, a high-risk region on the risk map was associated with an increased number of MDRO or extended-spectrum beta-lactamase (ESBL) positive returns.

Conclusion

Travellers showed a high willingness to use disinfectants. This preliminary study highlights the need for larger, randomized studies to better assess the true impact of hand disinfectants on MDRO acquisition.

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来源期刊

Travel Medicine and Infectious Disease PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECTIOUS DISEASES

CiteScore

19.40

自引率

1.70%

发文量

211

审稿时长

49 days

期刊介绍： Travel Medicine and Infectious Disease Publication Scope: Publishes original papers, reviews, and consensus papers Primary theme: infectious disease in the context of travel medicine Focus Areas: Epidemiology and surveillance of travel-related illness Prevention and treatment of travel-associated infections Malaria prevention and treatment Travellers' diarrhoea Infections associated with mass gatherings Migration-related infections Vaccines and vaccine-preventable disease Global policy/regulations for disease prevention and control Practical clinical issues for travel and tropical medicine practitioners Coverage: Addresses areas of controversy and debate in travel medicine Aims to inform guidelines and policy pertinent to travel medicine and the prevention of infectious disease Publication Features: Offers a fast peer-review process Provides early online publication of accepted manuscripts Aims to publish cutting-edge papers