{"title":"Tuesday 17 September 2024 SIG session","authors":"","doi":"10.1111/tme.13086","DOIUrl":"https://doi.org/10.1111/tme.13086","url":null,"abstract":"","PeriodicalId":23306,"journal":{"name":"Transfusion Medicine","volume":"14 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142267288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors for red blood cell alloimmunization in patients with hematologic malignancy","authors":"Pakthipa Pattarakosol, Nattarat Lorucharoen, Phandee Watanaboonyongcharoen, Ponlapat Rojnuckarin","doi":"10.1111/tme.13096","DOIUrl":"https://doi.org/10.1111/tme.13096","url":null,"abstract":"IntroductionPatients with hematologic malignancy have a higher risk of developing red blood cell (RBC) alloimmunization which can delay blood transfusion. Information on the risk factors for alloimmunization in this group is still limited. This study aimed to determine the prevalence and predictors of RBC alloimmunization among these patients.Materials and MethodsElectronic medical records of the patients with acute myeloid leukaemia (AML), acute lymphoid leukaemia (ALL), multiple myeloma (MM) and lymphoma from a tertiary care hospital between January 2018 and December 2022 were retrospectively reviewed. Clinical, demographic and transfusion history data of the included patients were analysed.ResultsOf the 983 patients with hematologic malignancy, 798 were included in the study. The prevalence of RBC alloantibodies in this population was 4.8% (38 patients). The alloimmunization rate of each subgroup was as followed: AML 9.1%, ALL 2.9%, MM 3.8% and lymphoma 2.5%. The most common alloantibodies were anti‐Mi<jats:sup>a</jats:sup>, anti‐E and anti‐Le<jats:sup>a</jats:sup>. The majority (29/38, 76.3%) of alloimmunization had a single alloantibody. RBC autoantibody was detected in 10 patients. The detection of autoantibodies and having AML were independently associated with RBC alloimmunization (adjusted odds ratio [aOR] 13.41, 95% confidence interval [CI] 2.00–89.72, <jats:italic>p</jats:italic> = 0.007 and aOR 11.44, 95% CI 2.02–64.72, <jats:italic>p</jats:italic> = 0.006, respectively).ConclusionThe prevalence of RBC alloimmunization in the patients with hematologic malignancy was 4.8%. The alloimmunization rate of the AML subgroup was higher than those of other hematologic malignancies. The detection of autoantibodies and the AML diagnosis were identified as potential risk factors for RBC alloimmunization.","PeriodicalId":23306,"journal":{"name":"Transfusion Medicine","volume":"27 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142217242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implementation challenges of electronic blood transfusion safety systems: Lessons from an international, multi‐site comparative case study","authors":"Stijn Horck, Nick Fahy, Trisha Greenhalgh","doi":"10.1111/tme.13095","DOIUrl":"https://doi.org/10.1111/tme.13095","url":null,"abstract":"BackgroundSevere transfusion reactions resulting from errors in matching the correct blood with the correct patient are considered never events. Despite the relative technical simplicity of barcode scanning for patient‐blood bag matching, the adoption and universal application of this safety measure are by no means universal. This study highlights the logistical and institutional challenges associated with spreading, scaling up, and sustaining such IT‐supported safety measures in healthcare.Study Design and MethodsWe report findings from a 5‐year, prospective, multi‐site case study conducted across one hospital in England and three hospitals in the Netherlands. Ethnographic methods, including interviews and observations, were used at each site to investigate the implementation of barcode scanning‐supported safety pathways for blood transfusions.ResultsSignificant variation was observed across the sites in the adoption and implementation of barcode scanning‐supported safety pathways. Despite the potential for reducing transfusion errors, the introduction of this innovation was met with varying levels of success in different settings.DiscussionThis study highlights the critical role of inter‐hospital learning and flexible system design in successfully implementing barcode scanning‐supported safety pathways for blood transfusions. A more structured, national‐level network for knowledge sharing could enhance the spread and sustainability of such innovations across healthcare settings.","PeriodicalId":23306,"journal":{"name":"Transfusion Medicine","volume":"05 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142217244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
