发布求助
文献互助 智能选刊 最新文献

Trends in Microbiology最新文献

筛选
英文 中文
Neutrophils - an understudied bystander in dengue? 中性粒细胞--登革热中未被充分研究的旁观者？
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-11-01 Epub Date: 2024-05-14 DOI: 10.1016/j.tim.2024.04.011
Caroline Lin Lin Chua, Raika Francesca Morales, Po Ying Chia, Tsin Wen Yeo, Andrew Teo
{"title":"Neutrophils - an understudied bystander in dengue?","authors":"Caroline Lin Lin Chua, Raika Francesca Morales, Po Ying Chia, Tsin Wen Yeo, Andrew Teo","doi":"10.1016/j.tim.2024.04.011","DOIUrl":"10.1016/j.tim.2024.04.011","url":null,"abstract":"<p><p>Dengue is a mosquito-borne viral disease which causes significant morbidity and mortality each year. Previous research has proposed several mechanisms of pathogenicity that mainly involve the dengue virus and host humoral immunity. However, innate immune cells, such as neutrophils, may also play an important role in dengue, albeit a much less defined role. In this review, we discuss the emerging roles of neutrophils in dengue and their involvement in pathologies associated with severe dengue. We also describe the potential use of several neutrophil proteins as biomarkers for severe dengue. These studies suggest that neutrophils are important players in dengue, and a better understanding of neutrophil-dengue biology is urgently needed.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140945959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ancient environmental microbiomes and the cryosphere. 古环境微生物群与冰冻圈。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-31 DOI: 10.1016/j.tim.2024.09.010
Alexander D Williams, Vivian W Leung, Julian W Tang, Nishimura Hidekazu, Nobuhiro Suzuki, Andrew C Clarke, David A Pearce, Tommy Tsan-Yuk Lam
{"title":"Ancient environmental microbiomes and the cryosphere.","authors":"Alexander D Williams, Vivian W Leung, Julian W Tang, Nishimura Hidekazu, Nobuhiro Suzuki, Andrew C Clarke, David A Pearce, Tommy Tsan-Yuk Lam","doi":"10.1016/j.tim.2024.09.010","DOIUrl":"https://doi.org/10.1016/j.tim.2024.09.010","url":null,"abstract":"<p><p>In this review, we delineate the unique set of characteristics associated with cryosphere environments (namely, ice and permafrost) which present both challenges and opportunities for studying ancient environmental microbiomes (AEMs). In a field currently reliant on several assumptions, we discuss the theoretical and empirical feasibility of recovering microbial nucleic acids (NAs) from ice and permafrost with varying degrees of antiquity. We also summarize contamination control best practices and highlight considerations for the latest approaches, including shotgun metagenomics, and downstream bioinformatic authentication approaches. We review the adoption of existing software and provide an overview of more recently published programs, with reference to their suitability for AEM studies. Finally, we summarize outstanding challenges and likely future directions for AEM research.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tackling coinfections. 应对合并感染。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-23 DOI: 10.1016/j.tim.2024.10.003
Gordon D Brown, Pablo R Murcia, Andrew P Waters, Jose Penades, Alberto Muñoz
{"title":"Tackling coinfections.","authors":"Gordon D Brown, Pablo R Murcia, Andrew P Waters, Jose Penades, Alberto Muñoz","doi":"10.1016/j.tim.2024.10.003","DOIUrl":"https://doi.org/10.1016/j.tim.2024.10.003","url":null,"abstract":"<p><p>Mechanistic understanding of the impact of coinfections is a critical knowledge gap. A workshop on coinfections highlighted key aspects required to advance this field, including identifying the coinfection priorities, creating research platforms for this type of research, promoting cross-expertise collaborations, and securing funding to support cross-kingdom pathogen research.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A unique bacterial family strikes again! 一个独特的细菌家族再次出现！
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-22 DOI: 10.1016/j.tim.2024.10.002
Gyanesh Shukla, Gaurav Sharma
{"title":"A unique bacterial family strikes again!","authors":"Gyanesh Shukla, Gaurav Sharma","doi":"10.1016/j.tim.2024.10.002","DOIUrl":"https://doi.org/10.1016/j.tim.2024.10.002","url":null,"abstract":"<p><p>Garcia et al. recently identified a novel myxobacterial family, Pendulisporaceae, encompassing four strains with novel biosynthetic gene clusters. This study underscores the value of exploring underrepresented microbial taxa for novel natural products, highlighting the potential of the family Pendulisporaceae as a source of new antimicrobial and therapeutic agents.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clostridium perfringens. 产气荚膜梭菌
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-18 DOI: 10.1016/j.tim.2024.09.009
Prabhat K Talukdar, Saeed Banawas, Mahfuzur R Sarker
{"title":"Clostridium perfringens.","authors":"Prabhat K Talukdar, Saeed Banawas, Mahfuzur R Sarker","doi":"10.1016/j.tim.2024.09.009","DOIUrl":"https://doi.org/10.1016/j.tim.2024.09.009","url":null,"abstract":"","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of noncoding RNAs in bacterial immunity. 非编码 RNA 在细菌免疫中的作用。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-12 DOI: 10.1016/j.tim.2024.09.006
David Mayo-Muñoz, Huijuan Li, Mario Rodríguez Mestre, Rafael Pinilla-Redondo
{"title":"The role of noncoding RNAs in bacterial immunity.","authors":"David Mayo-Muñoz, Huijuan Li, Mario Rodríguez Mestre, Rafael Pinilla-Redondo","doi":"10.1016/j.tim.2024.09.006","DOIUrl":"https://doi.org/10.1016/j.tim.2024.09.006","url":null,"abstract":"<p><p>The evolutionary arms race between bacteria and phages has driven the development of diverse anti-phage defense mechanisms. Recent studies have identified noncoding RNAs (ncRNAs) as key players in bacteria-phage conflicts, including CRISPR-Cas, toxin-antitoxin (TA), and reverse transcriptase (RT)-based defenses; however, our understanding of their roles in immunity is still emerging. In this review, we explore the multifaceted roles of ncRNAs in bacterial immunity, offering insights into their contributions to defense and anti-defense mechanisms, their influence on immune regulatory networks, and potential biotechnological applications. Finally, we highlight key outstanding questions in the field to spark future research directions.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balancing act: counteracting adverse drug effects on the microbiome. 平衡之术：抵消药物对微生物群的不良影响。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-11 DOI: 10.1016/j.tim.2024.09.011
Jacobo de la Cuesta-Zuluaga, Patrick Müller, Lisa Maier
{"title":"Balancing act: counteracting adverse drug effects on the microbiome.","authors":"Jacobo de la Cuesta-Zuluaga, Patrick Müller, Lisa Maier","doi":"10.1016/j.tim.2024.09.011","DOIUrl":"https://doi.org/10.1016/j.tim.2024.09.011","url":null,"abstract":"<p><p>The human gut microbiome, a community of microbes that plays a crucial role in our wellbeing, is highly adaptable but also vulnerable to drug treatments. This vulnerability can have serious consequences for the host, for example, increasing susceptibility to infections, immune, metabolic, and cognitive disorders. However, the microbiome's adaptability also provides opportunities to prevent, protect, or even reverse drug-induced damage. Recently, several innovative approaches have emerged aimed at minimizing the collateral damage of drugs on the microbiome. Here, we outline these approaches, discuss their applicability in different treatment scenarios, highlight current challenges, and suggest avenues that may lead to an effective protection of the microbiome.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loading and unloading plasmid cargoes. 装载和卸载质粒货物。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-10 DOI: 10.1016/j.tim.2024.09.012
James P J Hall
{"title":"Loading and unloading plasmid cargoes.","authors":"James P J Hall","doi":"10.1016/j.tim.2024.09.012","DOIUrl":"https://doi.org/10.1016/j.tim.2024.09.012","url":null,"abstract":"<p><p>Plasmids are vehicles for horizontal gene transfer between cells, but they also exchange genes with associated chromosomes in a process termed 'intracellular mobility'. I discuss a recent article by Kadibalban et al. mapping such plasmid-chromosomal sequence similarities across diverse bacteria.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142406918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diverse molecular mechanisms underpinning Staphylococcus aureus small colony variants. 金黄色葡萄球菌小菌落变异的多种分子机制。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-10 DOI: 10.1016/j.tim.2024.09.007
Maryam Mapar, Thomas Rydzak, Josefien W Hommes, Bas G J Surewaard, Ian A Lewis
{"title":"Diverse molecular mechanisms underpinning Staphylococcus aureus small colony variants.","authors":"Maryam Mapar, Thomas Rydzak, Josefien W Hommes, Bas G J Surewaard, Ian A Lewis","doi":"10.1016/j.tim.2024.09.007","DOIUrl":"https://doi.org/10.1016/j.tim.2024.09.007","url":null,"abstract":"<p><p>Small colony variants (SCVs) of Staphylococcus aureus are a relatively rare but clinically significant growth morphotype. Infections with SCVs are frequently difficult to treat, inherently antibiotic-resistant, and can lead to persistent infections. Despite a long history of research, the molecular underpinnings of this morphotype and their impact on the clinical trajectory of infections remain unclear. However, a growing body of literature indicates that SCVs are caused by a diverse range of molecular factors. These recent findings suggest that SCVs should be thought of as an ensemble collection of loosely related phenotypes, and not as a single phenomenon. This review describes the diverse mechanisms currently known to contribute to SCVs and proposes an ensemble model for conceptualizing this morphotype.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142406917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Azotobacter vinelandii. 醋兰氮杆菌
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2024-10-01 Epub Date: 2024-08-20 DOI: 10.1016/j.tim.2024.07.006
Brett M Barney
{"title":"Azotobacter vinelandii.","authors":"Brett M Barney","doi":"10.1016/j.tim.2024.07.006","DOIUrl":"10.1016/j.tim.2024.07.006","url":null,"abstract":"","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":null,"pages":null},"PeriodicalIF":14.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信