发布求助
文献互助 智能选刊 最新文献

Trends in Microbiology最新文献

筛选
英文 中文
Moonlighting antibiotics: the extra job of modulating biofilm formation. 兼职抗生素：调节生物膜形成的额外工作。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2025-01-18 DOI: 10.1016/j.tim.2024.12.011
Estefanía Cordisco, Diego Omar Serra
{"title":"Moonlighting antibiotics: the extra job of modulating biofilm formation.","authors":"Estefanía Cordisco, Diego Omar Serra","doi":"10.1016/j.tim.2024.12.011","DOIUrl":"10.1016/j.tim.2024.12.011","url":null,"abstract":"<p><p>The widespread use of antibiotics to treat bacterial infections has led to the common perception that their only function is to inhibit growth or kill bacteria. However, it has become clear that when antibiotics reach susceptible bacteria at non-lethal concentrations, they perform additional functions that significantly impact bacterial physiology, shaping both individual and collective behaviors. A key bacterial behavior influenced by sub-lethal antibiotic doses is biofilm formation, a multicellular, surface-associated mode of growth. This review explores different contexts in which natural and clinical antibiotics act as modulators of bacterial biofilm formation. We discuss cases that provide mechanistic insights into antibiotic modes of action, highlighting emerging common patterns and novel findings that pave the way for future research.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"459-471"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Funding and collaboration inequalities in infectious disease research - why does it matter? 传染病研究中的资金和合作不平等——为什么这很重要？
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2024-12-12 DOI: 10.1016/j.tim.2024.11.006
Gathsaurie Neelika Malavige, Guruprasad R Medigeshi, R Tedjo Sasmono, Chanaki Amaratunga
{"title":"Funding and collaboration inequalities in infectious disease research - why does it matter?","authors":"Gathsaurie Neelika Malavige, Guruprasad R Medigeshi, R Tedjo Sasmono, Chanaki Amaratunga","doi":"10.1016/j.tim.2024.11.006","DOIUrl":"10.1016/j.tim.2024.11.006","url":null,"abstract":"<p><p>To face the current and emerging challenges due to infectious diseases, global research communities must comprehend the challenges faced by scientists in low-income and lower-middle-income countries. Here we address pertinent issues regarding funding and collaboration inequalities that could potentially cripple economic and healthcare systems, escalating to bigger global threats.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"378-381"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiome selection and evolution within wild and domesticated plants. 野生和驯化植物的微生物选择和进化。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2024-12-18 DOI: 10.1016/j.tim.2024.11.011
Christopher James Barnes, Mo Bahram, Mogens Nicolaisen, M Thomas P Gilbert, Mette Vestergård
{"title":"Microbiome selection and evolution within wild and domesticated plants.","authors":"Christopher James Barnes, Mo Bahram, Mogens Nicolaisen, M Thomas P Gilbert, Mette Vestergård","doi":"10.1016/j.tim.2024.11.011","DOIUrl":"10.1016/j.tim.2024.11.011","url":null,"abstract":"<p><p>Microbes are ubiquitously found across plant surfaces and even within their cells, forming the plant microbiome. Many of these microbes contribute to the functioning of the host and consequently affect its fitness. Therefore, in many contexts, including microbiome effects enables a better understanding of the phenotype of the plant rather than considering the genome alone. Changes in the microbiome composition are also associated with changes in the functioning of the host, and there has been considerable focus on how environmental variables regulate plant microbiomes. More recently, studies suggest that the host genome also preconditions the microbiome to the environment of the plant, and the microbiome is therefore subject to evolutionary forces. Here, we outline how plant microbiomes are governed by both environmental variables and evolutionary processes and how they can regulate plant health together.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"447-458"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inclusion and diversity through a geographical lens.
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2025-03-12 DOI: 10.1016/j.tim.2025.02.017
Shankar Iyer
{"title":"Inclusion and diversity through a geographical lens.","authors":"Shankar Iyer","doi":"10.1016/j.tim.2025.02.017","DOIUrl":"10.1016/j.tim.2025.02.017","url":null,"abstract":"","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"373-374"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'Candidatus Methanoperedens'.
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2025-03-03 DOI: 10.1016/j.tim.2025.01.015
Hanna Zehnle, Marie C Schoelmerich
{"title":"'Candidatus Methanoperedens'.","authors":"Hanna Zehnle, Marie C Schoelmerich","doi":"10.1016/j.tim.2025.01.015","DOIUrl":"10.1016/j.tim.2025.01.015","url":null,"abstract":"","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"472-473"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Twists, turns and jumps: T6SS evolution within species.
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2025-03-11 DOI: 10.1016/j.tim.2025.02.015
Beth A Shen, S Brook Peterson, Joseph D Mougous
{"title":"Twists, turns and jumps: T6SS evolution within species.","authors":"Beth A Shen, S Brook Peterson, Joseph D Mougous","doi":"10.1016/j.tim.2025.02.015","DOIUrl":"10.1016/j.tim.2025.02.015","url":null,"abstract":"<p><p>The type VI secretion system mediates interbacterial antagonism between Gram-negative bacteria through delivery of toxic effector proteins. A recent comprehensive genomic analysis by Habich et al. reveals interesting features of the evolution of T6SSs and their corresponding effectors in Pseudomonas aeruginosa, raising questions about functional specialization of the system.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"382-384"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges of female microbial ecologists at different stages of their academic life: a Mexican perspective. 女性微生物生态学家在学术生涯不同阶段的挑战：墨西哥视角。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2024-12-12 DOI: 10.1016/j.tim.2024.11.002
Valeria Souza, Nguyen E López-Lozano, Ana E Escalante, Mirna Vazquez-Rosas-Landa, Gabriela Olmedo-Alvarez
{"title":"Challenges of female microbial ecologists at different stages of their academic life: a Mexican perspective.","authors":"Valeria Souza, Nguyen E López-Lozano, Ana E Escalante, Mirna Vazquez-Rosas-Landa, Gabriela Olmedo-Alvarez","doi":"10.1016/j.tim.2024.11.002","DOIUrl":"10.1016/j.tim.2024.11.002","url":null,"abstract":"<p><p>Latin American women scientists face a double glass ceiling because of cultural, institutional, and geographic biases, including those from international journal editors. Despite under-representation, they advance in science, technology, engineering, and mathematics (STEM), particularly microbiology. In Mexico, more efforts are needed to create an inclusive community, driving progress enriched by women's perspectives in science.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"375-377"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Closely related and yet special - how SPβ family phages control lysis-lysogeny decisions. SPβ家族噬菌体如何控制裂解-溶原性决定？
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2024-12-06 DOI: 10.1016/j.tim.2024.11.007
Katharina Kohm, Annabel V Clanner, Robert Hertel, Fabian M Commichau
{"title":"Closely related and yet special - how SPβ family phages control lysis-lysogeny decisions.","authors":"Katharina Kohm, Annabel V Clanner, Robert Hertel, Fabian M Commichau","doi":"10.1016/j.tim.2024.11.007","DOIUrl":"10.1016/j.tim.2024.11.007","url":null,"abstract":"<p><p>Soon after the discovery of genetic competence in the Gram-positive bacterium Bacillus subtilis, lytic and temperate phages that infect this organism were isolated. For instance, the lytic phage ϕ29 became a model for studying processes such as viral DNA packaging, replication, and transcription. By contrast, only a handful of temperate B. subtilis phages have been comprehensively characterized. However, the discovery of a peptide-based quorum sensing (QS) system in 2017 has brought temperate B. subtilis phages, particularly those of the SPβ family, back into the focus of research. The QS system is used by these phages to modulate lysis-lysogeny decisions. Meanwhile, many key components of the lysis-lysogeny management system have been identified. It turned out that a complex co-adaptation between the B. subtilis host cell and SPβ-like phages occurred during evolution and that a host-encoded toxin-antitoxin system plays a key role in controlling lysis-lysogeny decisions. There are many similarities and many important differences between the two well-studied model phages. Thus, a further comparative analysis of the lysis-lysogeny systems is essential to uncover the fundamental differences between ϕ3T and SPβ. Moreover, we believe that it would be exciting to revive research on temperate B. subtilis phages that are not related to SPβ-family phages.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"387-396"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing microbiota in vivo: debugging with medical imaging. 体内微生物群评估：医学成像调试。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2025-01-02 DOI: 10.1016/j.tim.2024.12.001
Donna E Goldhawk, Kait F Al, Sarah C Donnelly, Gabriel E Varela-Mattatall, Praveen Dassanayake, Neil Gelman, Frank S Prato, Jeremy P Burton
{"title":"Assessing microbiota in vivo: debugging with medical imaging.","authors":"Donna E Goldhawk, Kait F Al, Sarah C Donnelly, Gabriel E Varela-Mattatall, Praveen Dassanayake, Neil Gelman, Frank S Prato, Jeremy P Burton","doi":"10.1016/j.tim.2024.12.001","DOIUrl":"10.1016/j.tim.2024.12.001","url":null,"abstract":"<p><p>The microbiota is integral to human health and has been mostly characterized through various ex vivo 'omic'-based approaches. To better understand the real-time function and impact of the microbiota, in vivo molecular imaging is required. With technologies such as positron emission tomography (PET), magnetic resonance imaging (MRI), and computed tomography (CT), insight into microbiological processes may be coupled to in vivo information. Noninvasive imaging enables longitudinal tracking of microbes and their components in real time; mapping of microbiota biodistribution, persistence and migration; and simultaneous monitoring of host physiological responses. The development of molecular imaging for clinical translation is an interdisciplinary science, with broad implications for deeper understanding of host-microbe interactions and the role(s) of the microbiome in health and disease.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"408-420"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cell-free DNA: a promising biomarker in infectious diseases. 无细胞 DNA：传染性疾病中一种前景广阔的生物标记物。
IF 14 1区 生物学
Trends in Microbiology Pub Date : 2025-04-01 Epub Date: 2024-07-11 DOI: 10.1016/j.tim.2024.06.005
Yuxuan Hu, Yanping Zhao, Yan Zhang, Weijun Chen, Haiqiang Zhang, Xin Jin
{"title":"Cell-free DNA: a promising biomarker in infectious diseases.","authors":"Yuxuan Hu, Yanping Zhao, Yan Zhang, Weijun Chen, Haiqiang Zhang, Xin Jin","doi":"10.1016/j.tim.2024.06.005","DOIUrl":"10.1016/j.tim.2024.06.005","url":null,"abstract":"<p><p>Infectious diseases pose serious threats to public health worldwide. Conventional diagnostic methods for infectious diseases often exhibit low sensitivity, invasiveness, and long turnaround times. User-friendly point-of-care tests are urgently needed for early diagnosis, treatment monitoring, and prognostic prediction of infectious diseases. Cell-free DNA (cfDNA), a promising non-invasive biomarker widely used in oncology and pregnancy, has shown great potential in clinical applications for diagnosing infectious diseases. Here, we discuss the most recent cfDNA research on infectious diseases from both the pathogen and host perspectives. We also discuss the technical challenges in this field and propose solutions to overcome them. Additionally, we provide an outlook on the potential of cfDNA as a diagnostic, treatment, and prognostic marker for infectious diseases.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":"421-433"},"PeriodicalIF":14.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141601808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信