Transfusion最新文献_第7页

Genome-wide association of pica within a cohort of volunteer blood donors potentially implicates the gene encoding neuropeptide VF. 一组志愿献血者中异食癖的全基因组关联可能与编码神经肽VF的基因有关。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-02-18 DOI: 10.1111/trf.70130

Eric J Early, Hefei Liu, Bryan R Spencer, Grier P Page, Alan E Mast

{"title":"Genome-wide association of pica within a cohort of volunteer blood donors potentially implicates the gene encoding neuropeptide VF.","authors":"Eric J Early, Hefei Liu, Bryan R Spencer, Grier P Page, Alan E Mast","doi":"10.1111/trf.70130","DOIUrl":"10.1111/trf.70130","url":null,"abstract":"Background: Pica is an eating disorder characterized by the persistent craving and consumption of non-food substances such as ice, chalk, starch, or raw pasta. Pica symptoms are more common in people with iron deficiency and resolve upon treatment. Without iron supplementation, volunteer blood donors can become iron deficient after repeated donations, making them an ideal population to study pica.Study design and methods: A genome-wide association study (GWAS) was conducted with 12,157 volunteer blood donors within the Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) RBC-omics study. Three pica outcomes of interest were evaluated, including ice-only consumption, non-ice consumption, or either type of pica (combined). Candidate single nucleotide polymorphisms (SNPs) were tested for replication using all of us (AoU).Results: Within REDS-III, 2.4% of donors reported pica symptoms, and nine genome-wide significant SNPs were identified as associated with pica. Within a stratified European population of 7493 REDS-III donors, seven genome-wide significant SNPs were identified. Both overall and in the European stratum, ferritin levels were lower in pica cases than controls (36.0 ± 43.2 ng/mL vs. 53.3 ± 69.2 ng/mL overall and 33.8 ± 41.0 ng/mL vs. 43.8 ± 55.3 ng/mL). Of these, one SNP, rs73277282, near the gene encoding the neuropeptide VF (NPVF) replicated in the AoU dataset (REDS-III p = 1.53 x 10-8; AoU p = .02).Discussion: Neuropeptide VF has been previously shown to regulate food intake and energy balance, suggesting that polymorphisms associated with its expression may synergize with iron deficiency to produce pica behaviors.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"742-750"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12997437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative platelet activation profile between pooled granulocyte concentrates (PGC) versus apheresis (APC) and buffy coat (BC-PC) method. 浓缩粒细胞池法（PGC）与单采法（APC）和黄皮法（BC-PC）的血小板活化谱比较。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-03-07 DOI: 10.1111/trf.70098

Fabrice Cognasse, Karine Desseux, Véronique Artero, Veronique Duraffourg, Damien Crespe, Marie-Ange Eyraud, Charles-Antoine Arthaud, Amélie Prier, Victorine Maillot, Anne-Claire Duchez, Patricia Chavarin, Hind Hamzeh-Cognasse

{"title":"Comparative platelet activation profile between pooled granulocyte concentrates (PGC) versus apheresis (APC) and buffy coat (BC-PC) method.","authors":"Fabrice Cognasse, Karine Desseux, Véronique Artero, Veronique Duraffourg, Damien Crespe, Marie-Ange Eyraud, Charles-Antoine Arthaud, Amélie Prier, Victorine Maillot, Anne-Claire Duchez, Patricia Chavarin, Hind Hamzeh-Cognasse","doi":"10.1111/trf.70098","DOIUrl":"10.1111/trf.70098","url":null,"abstract":"Background: Granulocyte transfusion remains a therapeutic option for patients with severe neutropenia or granulocyte dysfunction, though its clinical benefit is still debated. Traditional pooled granulocyte concentrates (PGC) are produced by donor stimulation and apheresis, procedures that are costly and ethically restrictive. To overcome these limitations, PGC derived from buffy coat layers (BC) have emerged as a simpler and safer alternative, yet little is known about their platelet composition and activation profile.Study design /methods: Whole blood donations (n = 256) were processed into BC, pooled (20 BC per batch), and reconstituted to form PGC20 units. Hematologic parameters and platelet activation markers (CD41, CD62P, CD63) were analyzed by automated counting and flow cytometry and compared with standard apheresis (APC) and buffy coat-derived platelet concentrates (BC-PC).Results: PGC show a high platelet concentration comparable to BC-PC, with an increased mean platelet volume. The elevated expression of CD62P and CD63 confirms marked platelet activation, while the slight decrease in CD41 suggests membrane alteration during processing, indicating a mixed platelet-granulocyte product with immunomodulatory potential that requires optimization for safe transfusional use.Conclusions: PGC derived from buffy coat pools combines high granulocyte yield with an activated platelet population. This bioactive platelet component may enhance immune interactions but warrants further optimization to ensure transfusion safety and product standardization.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"656-663"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147373081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathogen-reduced plasma, cryoprecipitate reduced for therapeutic plasma exchange. 病原体减少血浆，低温沉淀减少治疗血浆交换。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-01-31 DOI: 10.1111/trf.70099

Florian Tupin, Clarisse Mouriaux, Beatrice Hechler, Kaja Kaastrup, Subra Yegneswaran, Laurence Corash, Pierre H Mangin

{"title":"Pathogen-reduced plasma, cryoprecipitate reduced for therapeutic plasma exchange.","authors":"Florian Tupin, Clarisse Mouriaux, Beatrice Hechler, Kaja Kaastrup, Subra Yegneswaran, Laurence Corash, Pierre H Mangin","doi":"10.1111/trf.70099","DOIUrl":"10.1111/trf.70099","url":null,"abstract":"Background: Therapeutic plasma exchange (TPE) for thrombotic thrombocytopenic purpura (TTP) and auto-immune disorders involves repeated patient exposure to allogenic plasma with the risk of transfusion-transmitted infection (TTI). Amotosalen-UVA Pathogen Reduction technology is FDA approved to manufacture pathogen-reduced plasma, cryoprecipitate reduced (PRPCR), a form of cryoprecipitate poor plasma (CPP) with potentially improved TPE outcomes and reduced TTI risk.Methods: PRPCR was manufactured from pathogen-reduced (PR) plasma. Thrombin generation, fibrinogen, Factors II, V, VII, VIII, IX, X, XI, XIII, VWF, ADAMTS13, Protein C, Protein S, α-2 plasmin inhibitor (α-2 PI), IgG, IgM, and IgA were measured. Microfluidic chamber assays at variable shear rates characterized PRPCR-mediated platelet adhesion and aggregation.Results: Compared to PR plasma, fibrinogen, Factor VIII, and VWF levels were depleted in PRPCR. Factors II, V, VII, IX, X, XI, XIII, thrombin generation, Protein C, Protein S, α-2 PI, ADAMTS13, and immunoglobulins were conserved. At low wall shear rates (300 s-1) PRPCR supported platelet adhesion. Perfusion of plasma-free blood containing PRPCR flowed over immobilized VWF binding peptide (100 μg/mL) and showed absence of platelet adhesion. Perfusion of plasma-free blood containing PRPCR flowed over immobilized collagen (200 μg/mL) at high wall shear rate (1500 s-1) and demonstrated no platelet thrombus formation.Conclusions: PRPCR retained hemostatic capacity, anti-thrombotic proteins, and ADAMTS13, but collagen induced platelet aggregation was negligible at high shear due to depletion of functional high molecular weight VWF. PRPCR is a CPP option for TPE with reduced platelet-mediated thrombotic risk and TTI risk, but with retention of plasma hemostatic capacity and immunoglobulins.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"664-676"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and feasibility of cold-stored uncrossmatched whole blood transfusion in civilian non-trauma patients. 冷藏非交叉配型全血输注平民非创伤患者的安全性和可行性。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-03-11 DOI: 10.1111/trf.70145

Emmanuel A Fadeyi, Joshua Cox-Jones, Jordan Staggs, Abdelrahman Alwan, Amit K Saha, Ashley J Crosby, Gregory J Pomper

{"title":"Safety and feasibility of cold-stored uncrossmatched whole blood transfusion in civilian non-trauma patients.","authors":"Emmanuel A Fadeyi, Joshua Cox-Jones, Jordan Staggs, Abdelrahman Alwan, Amit K Saha, Ashley J Crosby, Gregory J Pomper","doi":"10.1111/trf.70145","DOIUrl":"10.1111/trf.70145","url":null,"abstract":"Background: There is evidence in the civilian population that resuscitation using group O low titer whole blood (WB) may provide survival benefits to traumatically injured patients. However, there is limited information in the literature concerning the use of WB in non-trauma patients requiring resuscitation. The outcome of patients presenting with non-traumatic hemorrhage who received WB resuscitation was investigated.Study design and methods: Existing data of all adults ≥18 years old who received WB transfusion either as massive transfusion or emergency release blood transfusion at our institution were reviewed from April 2018 to December 2024. Non-trauma patients were stratified into three indication categories (GI bleed, nonoperative hemorrhage, and operative hemorrhage). The primary outcome measure was mortality at 24 h.Results: A total of 331 non-trauma patients received WB in our cohort. The overall 24-h mortality rate was 18.7%, whereas the overall in-hospital 30-day mortality was 46.8%. The most common etiology of non-traumatic hemorrhage was GI bleeding (43.8%, n = 145/331). Nonoperative 24-h mortality was statistically higher than other indication categories. The ICU length of stay and number of WB units transfused was also statistically higher for the operative category. Three patients experienced one allergic and two delayed hemolytic transfusion reactions.Discussion: This study demonstrates that the use of WB in non-trauma patients is associated with a decreased 24 h in-hospital mortality with either operative or GI bleed when compared to nonoperative WB transfusion. Emergent severely hemorrhaging non-trauma patients can receive WB transfusions safely without any increased transfusion related adverse effects.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"777-783"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147435643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sentinel trends in donor hemoglobin values and low-hemoglobin deferrals in a large US blood center. 美国一个大型血液中心供体血红蛋白值和低血红蛋白延迟的前哨趋势。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-02-05 DOI: 10.1111/trf.70116

Ruchika Goel, Marjorie Bravo, Courtney Hopkins, Ralph Vassallo

{"title":"Sentinel trends in donor hemoglobin values and low-hemoglobin deferrals in a large US blood center.","authors":"Ruchika Goel, Marjorie Bravo, Courtney Hopkins, Ralph Vassallo","doi":"10.1111/trf.70116","DOIUrl":"10.1111/trf.70116","url":null,"abstract":"Background: Low hemoglobin (Hb) is the leading cause of blood donor deferral yet mean Hb values are seldom examined as sentinel indicators of changes in donor recruitment, assessment, or testing. Case in point, following unexplained improvement in these parameters, U.S. blood centers observed a sharp rise in low-Hb deferrals after the 2024 introduction of a new international calibrator for some fingerstick hemoglobinometers.Methods: We retrospectively analyzed 15 years (2010-2024) of allogeneic donor data from a national blood center. Mean donor Hb and low-Hb deferral rates were trended overall and by sex, cognizant of temporal practices affecting values like a ferritin testing program, the 2016 male Hb cutoff adjustment, and acceptance of allogeneic donors with testosterone-associated polycythemia.Results: Among >11 million presentations (49.8% female), mean Hb values rose progressively from 2016 through 2023, correlating with a suspected gradual positive bias from a degrading hemoglobinometry standard. Female low-Hb deferrals declined from 12.2% (2016) to 7.7% (2023) before rebounding to 2016 levels in 2024 following recalibration. Male mean Hb trends were additionally influenced by increasing testosterone use in the donor base and the higher 13.0 g/dL Hb cutoff. Ferritin-based deferral programs temporarily raised mean Hb and reduced low-Hb deferrals, which reversed when suspended.Discussion: Hemoglobinometer calibration drift, a ferritin testing policy, and donor testosterone use together shaped long-term donor Hb trends. Surveillance of mean donor Hb should be treated as a sentinel metric, and unexpected declines and increases in related deferral rates warrant the same scrutiny to protect both donors and blood availability.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"720-727"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146120323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benefits of isovolemic hemodilution red cell exchange: Real or imagined? 等容血稀释红细胞交换的益处：真实的还是想象的？

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-03-12 DOI: 10.1111/trf.70166

Blake Nourse, Manasa Reddy, Jennifer Jones, Minh-Ha Tran

{"title":"Benefits of isovolemic hemodilution red cell exchange: Real or imagined?","authors":"Blake Nourse, Manasa Reddy, Jennifer Jones, Minh-Ha Tran","doi":"10.1111/trf.70166","DOIUrl":"10.1111/trf.70166","url":null,"abstract":"Background: Isovolemic hemodilution red cell exchange (IHD-RCE) (as compared to standard, or STD-RCE) may: reduce per-procedure RBC use, result in a lower fraction of cells remaining (FCR), and provide an \"iron unloading\" benefit. We review the published literature to explore whether these benefits have been realized in real-world settings.Methods: A literature search was conducted in PubMed, Embase, EBSCOhost, and Cochrane Library. Additional studies were identified through bibliography review. To be included, studies required STD-RCE versus IHD-RCE comparison groups. Data, including RBC utilization, actual FCR, ferritin levels, pre-hemoglobin S% (HbS%), and procedure intervals were extracted and analyzed using descriptive statistics.Results: The initial search and bibliography review yielded 70 studies; 48 were excluded for not meeting inclusion criteria; of the remainder, 3 reports met full inclusion criteria and were retained for data extraction. Compared to STD-RCE, IHD-RCE reliably reduced red cell requirements, with reduction (in mL/mL Total Blood Volume) from 0.55 (0.42-0.66) to 0.49 (0.34-0.54), among 15 patients (p = 0.02); and (in mL/kg) from 39.5 ± 4.6 to 35.5 ± 4.1 (p < 0.001) in another 20 patients. While actual FCR was lower than programmed FCR with both STD-RBCx and IHD-RBCx, the magnitude of this difference was not significantly different (n = 15). Among 26 patients for whom ferritin levels were reported, a clear reduction was not observed. Furthermore, no clear safety signals were observed.Conclusions: Conversion to IHD-RCE appears safe and reduces per-procedure RBC utilization by approximately 1 unit. IHD-RCE did not demonstrate a clear iron-unloading benefit over STD-RCE.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"763-769"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An unusual case of short tandem repeat analysis with foreign peaks due to granulocyte transfusion. 一个不寻常的短串联重复分析与外国峰由于粒细胞输血。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 DOI: 10.1111/trf.70201

Brian Nguyen, Danica Wiredja, Louise Helander, Kyle Annen

引用次数: 0

Automated cell count for blood component quality control. 用于血液成分质量控制的自动细胞计数。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-01-31 DOI: 10.1111/trf.70101

Gemma Aran, Silvia Torrents, Margarita Blanco, Nicole Somarriba, F Javier Algar, Fatima Shettiyar, Laura Galvez, Sara Lopez, Begoña Amill, Mireia Lloret, Sergi Torramade-Moix, Núria Martinez-Llonch, Glòria Soria, Margarita Codinach

{"title":"Automated cell count for blood component quality control.","authors":"Gemma Aran, Silvia Torrents, Margarita Blanco, Nicole Somarriba, F Javier Algar, Fatima Shettiyar, Laura Galvez, Sara Lopez, Begoña Amill, Mireia Lloret, Sergi Torramade-Moix, Núria Martinez-Llonch, Glòria Soria, Margarita Codinach","doi":"10.1111/trf.70101","DOIUrl":"10.1111/trf.70101","url":null,"abstract":"Background: Accurate quantification of residual leukocytes (rWBC) and red blood cells (rRBC) in leukoreduced blood components is essential to ensure product quality and transfusion safety. Conventional manual flow cytometry techniques are time-consuming and analyst-dependent. In this study, we validated the XN-1000 Blood Bank (BB) mode as an automated alternative and compared its performance with our standard quality control (QC) workflow.Study design and methods: The BB mode was validated for precision, linearity, and carry-over in detecting residual cells in red blood cell concentrates, platelet concentrates, and plasma products. Results obtained were compared to those of manual flow cytometry (for rWBC and rRBC) and impedance-based hematology analysis (for platelet counts) across over 1000 blood components.Results: Methods validation showed high linearity, acceptable precision at low cell concentrations, and no analytical interference. Comparison between workflows revealed similar results for hemoglobin, hematocrit, and leukocyte counts. rRBC values measured by BB mode were ~2.3-fold higher than those obtained by manual flow cytometry, although all values remained within product specifications. Platelet counts were consistently higher with BB mode (PLT-F) than with impedance, with a 15-51% increase depending on the product. Flow cytometry confirmed that PLT-F results better reflect the true platelet content than impedance.Conclusion: The XN-1000 BB mode is a reliable and efficient alternative to manual methods for QC monitoring of blood components. It offers accurate residual cell quantification, increases laboratory throughput, and simplifies workflows.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"784-793"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Motivations to donate blood and plasma: A scoping review of quantitative studies. 捐献血液和血浆的动机：定量研究的范围综述。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-03-09 DOI: 10.1111/trf.70137

Pedro Suárez-Artime, Julia Rey-Brandariz, Marisa López García, Beatriz Casal Acción, Alejandro de Rivero de Aguilar Pensado, Leonor Varela-Lema

{"title":"Motivations to donate blood and plasma: A scoping review of quantitative studies.","authors":"Pedro Suárez-Artime, Julia Rey-Brandariz, Marisa López García, Beatriz Casal Acción, Alejandro de Rivero de Aguilar Pensado, Leonor Varela-Lema","doi":"10.1111/trf.70137","DOIUrl":"10.1111/trf.70137","url":null,"abstract":"Introduction: Effective recruitment and retention of donors are essential for the supply of blood components and blood-derived medicines. In many high-income Western countries, there is an imbalance between demand and production of blood-derived medicines. Motivational factors behind donations range from altruism and health concerns to incentives or responding to a need from friends or family. Motivations might differ according to beliefs and social norms. The aim of this review was to identify the motivations that influence blood and plasma donation behavior in high-income Western countries.Materials and methods: We conducted a scoping review following the PRISMA-ScR guidelines. A comprehensive search was performed in MEDLINE, EMBASE and CINAHL for studies published from 2013 onwards that examined motivations for blood or plasma donation in high-income Western countries. Reported motivations were coded and grouped into predefined categories and subcategories.Results: Thirty-eight studies including 147,010 participants met the inclusion criteria. Most studies assessed motivations for blood donation, while few focused on plasma donation. Across studies, prosocial motivations were the most frequently reported drivers of donation. Among blood donors, altruistic reasons such as helping others and social responsibility predominated. Non-donors more often cited collectivist motives, such as donating when a friend or relative needed blood. For plasma donation, prosocial motivations remained important, although incentives were cited more often than for blood donation.Discussion: Prosocial motivations, particularly altruism and personal values, are the main drivers of blood and plasma donation in high-income Western countries. However, motivations vary across donor groups and between blood and plasma donation.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"853-870"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of a novel RHD*01W allele with c.175G>T on the RHD*weak partial 15 allele background. 在RHD*弱部分15等位基因背景下，一个带有c.175G>T的RHD*01W等位基因的鉴定。

IF 2 3区医学

Transfusion Pub Date : 2026-04-01 Epub Date: 2026-02-11 DOI: 10.1111/trf.70120

Xu Zhang, Zhu-Ren Zhou, Xu-Ying Huang, Li-Chun Li, Xiao-Feng Li, Jian-Ping Li

引用次数: 0